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The map label for this gene is yqcB [C]

Identifier: 157960378

GI number: 157960378

Start: 674518

End: 675456

Strand: Direct

Name: yqcB [C]

Synonym: Spea_0549

Alternate gene names: 157960378

Gene position: 674518-675456 (Clockwise)

Preceding gene: 157960377

Following gene: 157960380

Centisome position: 13.04

GC content: 47.18

Gene sequence:

>939_bases
ATGAGTTCCTCTGTTCGTGCCACCCAAGCTTCTTATGTAGTGTTACCTGAAACGGTAACCGATAAACCTACCGTGCTTAG
CTTCCTTGTGAGCCAATTTCCAGCAATAGCCGAAGCGGTTTGGCAAAAGCGCATTGTTGACGGTAAAGTCCATTGGCGTG
ATGGCACGCTTATTACGGCTCAAACGGCGTTTATTCCCCGCGAGCGGGTCTACTATTACCGAGAAGTGGAGCAGGAGTCA
TTAATTCCTTTCAAAGAAAAATGCTTGTTGCAAACAGACGAGTTTCTGTTGGTATTCAAGCCTCACTTTTTGGCGGTCAA
TCCGAGCGGCAACTTCGTCAATGAGTGTCTGGTGAATCGGTTACGCTTAAAAACGGGTAATCAGCAAATCGTCGCGGCTC
ATCGTCTAGACAGAGCGACGGCGGGGGTGATGTTACTGAGTCAGAAGAGCGAGACTCGTCATGATTATCACGAGTTGTTC
AAGAGTGGCCAGATCCAAAAGACCTACCAAGCGGTTGCACCATTAAACAATCAAATCAAGCAAATGTTAGAGCAAGGCTC
TCTGACTCTGCCTATGCATTGGACGGTGAAGAACCGGATAAGCAAAACGACTCCCAGTTTTAGAATGTGTATTAGCGACG
GGGAGGCGAATAGCCACTCAGAGATCCGTTTAATCGAGACTTTTGGAGGCTATGGCCTGTTCGAGCTAGTCCCTGTAACG
GGGCGGACTCATCAACTCAGAGTGCATATGATGAGCCTTGGCATGTCTATTCTTAATGATAGACTCTACCCCGAGTTACT
CGATAAAGCCGCTGATGATTTTGCAAAGCCACTCAAGTTAATGGCAAGGCGACTCAGTTTTACCGACCCCATCACTGATG
AAGATGTCGATGTGAGTTGCGACGGCTTTAACCTACAAGATGAAGTACAAAATCTATAA

Upstream 100 bases:

>100_bases
ATGGCAGATTGTTTATTGATAGTCGATAGTTTTTTGATAGTAGACCGAGTTTTGCTAGAGTAGCGTCACTTCTGTTTAGC
CCTCTTATGTTTTGAGTCTT

Downstream 100 bases:

>100_bases
ATGTTATTACTGACTTTTGATAGATTTATTCTTGCTAGGACCTAGGACCTAGGACCTAGGACCTAGGACCTAGGACCTAG
GACCAGGCTTAGAACGCTCG

Product: pseudouridine synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSSSVRATQASYVVLPETVTDKPTVLSFLVSQFPAIAEAVWQKRIVDGKVHWRDGTLITAQTAFIPRERVYYYREVEQES
LIPFKEKCLLQTDEFLLVFKPHFLAVNPSGNFVNECLVNRLRLKTGNQQIVAAHRLDRATAGVMLLSQKSETRHDYHELF
KSGQIQKTYQAVAPLNNQIKQMLEQGSLTLPMHWTVKNRISKTTPSFRMCISDGEANSHSEIRLIETFGGYGLFELVPVT
GRTHQLRVHMMSLGMSILNDRLYPELLDKAADDFAKPLKLMARRLSFTDPITDEDVDVSCDGFNLQDEVQNL

Sequences:

>Translated_312_residues
MSSSVRATQASYVVLPETVTDKPTVLSFLVSQFPAIAEAVWQKRIVDGKVHWRDGTLITAQTAFIPRERVYYYREVEQES
LIPFKEKCLLQTDEFLLVFKPHFLAVNPSGNFVNECLVNRLRLKTGNQQIVAAHRLDRATAGVMLLSQKSETRHDYHELF
KSGQIQKTYQAVAPLNNQIKQMLEQGSLTLPMHWTVKNRISKTTPSFRMCISDGEANSHSEIRLIETFGGYGLFELVPVT
GRTHQLRVHMMSLGMSILNDRLYPELLDKAADDFAKPLKLMARRLSFTDPITDEDVDVSCDGFNLQDEVQNL
>Mature_311_residues
SSSVRATQASYVVLPETVTDKPTVLSFLVSQFPAIAEAVWQKRIVDGKVHWRDGTLITAQTAFIPRERVYYYREVEQESL
IPFKEKCLLQTDEFLLVFKPHFLAVNPSGNFVNECLVNRLRLKTGNQQIVAAHRLDRATAGVMLLSQKSETRHDYHELFK
SGQIQKTYQAVAPLNNQIKQMLEQGSLTLPMHWTVKNRISKTTPSFRMCISDGEANSHSEIRLIETFGGYGLFELVPVTG
RTHQLRVHMMSLGMSILNDRLYPELLDKAADDFAKPLKLMARRLSFTDPITDEDVDVSCDGFNLQDEVQNL

Specific function: Unknown

COG id: COG0564

COG function: function code J; Pseudouridylate synthases, 23S RNA-specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786244, Length=205, Percent_Identity=30.7317073170732, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787327, Length=233, Percent_Identity=29.1845493562232, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534965, Length=202, Percent_Identity=27.2277227722772, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320168, Length=252, Percent_Identity=23.015873015873, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006225
- InterPro:   IPR006224
- InterPro:   IPR006145
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 35505; Mature: 35374

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS01129 PSI_RLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSVRATQASYVVLPETVTDKPTVLSFLVSQFPAIAEAVWQKRIVDGKVHWRDGTLITA
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEE
QTAFIPRERVYYYREVEQESLIPFKEKCLLQTDEFLLVFKPHFLAVNPSGNFVNECLVNR
EEHHCCHHHHHHHHHHCHHHCCCHHHHHHHCCCCEEEEEECEEEEECCCCCHHHHHHHHH
LRLKTGNQQIVAAHRLDRATAGVMLLSQKSETRHDYHELFKSGQIQKTYQAVAPLNNQIK
HHHCCCCCEEEHHHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
QMLEQGSLTLPMHWTVKNRISKTTPSFRMCISDGEANSHSEIRLIETFGGYGLFELVPVT
HHHHCCCEEEEEEEHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECC
GRTHQLRVHMMSLGMSILNDRLYPELLDKAADDFAKPLKLMARRLSFTDPITDEDVDVSC
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
DGFNLQDEVQNL
CCCCCHHHHHCC
>Mature Secondary Structure 
SSSVRATQASYVVLPETVTDKPTVLSFLVSQFPAIAEAVWQKRIVDGKVHWRDGTLITA
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEE
QTAFIPRERVYYYREVEQESLIPFKEKCLLQTDEFLLVFKPHFLAVNPSGNFVNECLVNR
EEHHCCHHHHHHHHHHCHHHCCCHHHHHHHCCCCEEEEEECEEEEECCCCCHHHHHHHHH
LRLKTGNQQIVAAHRLDRATAGVMLLSQKSETRHDYHELFKSGQIQKTYQAVAPLNNQIK
HHHCCCCCEEEHHHHHHHHHHCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
QMLEQGSLTLPMHWTVKNRISKTTPSFRMCISDGEANSHSEIRLIETFGGYGLFELVPVT
HHHHCCCEEEEEEEHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEECC
GRTHQLRVHMMSLGMSILNDRLYPELLDKAADDFAKPLKLMARRLSFTDPITDEDVDVSC
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
DGFNLQDEVQNL
CCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8661927 [H]