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The map label for this gene is ykvO [H]

Identifier: 157960361

GI number: 157960361

Start: 656680

End: 657342

Strand: Reverse

Name: ykvO [H]

Synonym: Spea_0532

Alternate gene names: 157960361

Gene position: 657342-656680 (Counterclockwise)

Preceding gene: 157960362

Following gene: 157960360

Centisome position: 12.7

GC content: 50.38

Gene sequence:

>663_bases
ATGATATTAATTTCCGGAGCCAGTAGCGGATTAGGCGCAGCGCTCGCCAAACGTTATGGCGCAGAACAACCAATTTGTAT
CAGTGGTCGCAATAGCGAGCGTTTACAGCTAGTTGCGAAAGAGGTAAGCCAGCCTTGTCAGGCCCAGGTTACCGACCTTT
GTGATGCGAGTGCCGTTGAGTCCCTATTCGATAACCTCCCAACGACGCCATCCTTGATTATCCATAGCGCAGGCAGTGGT
TATTTTGGCCCTATCGAGTCTCAGTCTCCAGAGGCCATTAAAGACCTACTCAATAACAATGTGACTTCGGCAATTTTTTT
GCTGCGCGAGGCGGTGAAACGTTATAAAGAGCAAAATGTGACAGTCGTGATAGTGATGTCGACTGCGGCGCTGGTACCTA
AGGCTGAAGAGTCAACCTACTGCGCAGCTAAGTGGGCGGTTAAGGGGTTAATTGAATCGGTGCGTCTAGAGCTTAAGAAT
AGCCCGATGAAGCTGATTGCCGTCTATCCAGGTGGCATGGACACAGACTTTTGGCCGAGCAGCGGCAAAATAGCTAACAC
CAGCAGCTTTATGAGCGCCGATGAAGCGGCTGGCATGCTAAAGCAGGCACTGCAAAGTACTGAGCATGGTTATATAGCCG
ATCTGACCATAGCCCGAGGTTAG

Upstream 100 bases:

>100_bases
TGGCCAGCAAGTAGACTTCGAACAAGCCATTCTCGAGATCGAATAAGCTCGCTTAGCCAAGATAACGCAACACGCAATTT
AGCAAAGAGTAAGGACCAAT

Downstream 100 bases:

>100_bases
TCAGCGACTCAGAGAGCAAAGGCTAAGATAAAGAACAAATAATCGCAGTGTAACTATACTTATATCAAACTAACCGATTA
TCAATCTGACTCTAAAATAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MILISGASSGLGAALAKRYGAEQPICISGRNSERLQLVAKEVSQPCQAQVTDLCDASAVESLFDNLPTTPSLIIHSAGSG
YFGPIESQSPEAIKDLLNNNVTSAIFLLREAVKRYKEQNVTVVIVMSTAALVPKAEESTYCAAKWAVKGLIESVRLELKN
SPMKLIAVYPGGMDTDFWPSSGKIANTSSFMSADEAAGMLKQALQSTEHGYIADLTIARG

Sequences:

>Translated_220_residues
MILISGASSGLGAALAKRYGAEQPICISGRNSERLQLVAKEVSQPCQAQVTDLCDASAVESLFDNLPTTPSLIIHSAGSG
YFGPIESQSPEAIKDLLNNNVTSAIFLLREAVKRYKEQNVTVVIVMSTAALVPKAEESTYCAAKWAVKGLIESVRLELKN
SPMKLIAVYPGGMDTDFWPSSGKIANTSSFMSADEAAGMLKQALQSTEHGYIADLTIARG
>Mature_220_residues
MILISGASSGLGAALAKRYGAEQPICISGRNSERLQLVAKEVSQPCQAQVTDLCDASAVESLFDNLPTTPSLIIHSAGSG
YFGPIESQSPEAIKDLLNNNVTSAIFLLREAVKRYKEQNVTVVIVMSTAALVPKAEESTYCAAKWAVKGLIESVRLELKN
SPMKLIAVYPGGMDTDFWPSSGKIANTSSFMSADEAAGMLKQALQSTEHGYIADLTIARG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787526, Length=190, Percent_Identity=28.4210526315789, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=241, Percent_Identity=26.1410788381743, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007236, Length=234, Percent_Identity=23.5042735042735, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23415; Mature: 23415

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILISGASSGLGAALAKRYGAEQPICISGRNSERLQLVAKEVSQPCQAQVTDLCDASAVE
CEEEECCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHH
SLFDNLPTTPSLIIHSAGSGYFGPIESQSPEAIKDLLNNNVTSAIFLLREAVKRYKEQNV
HHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
TVVIVMSTAALVPKAEESTYCAAKWAVKGLIESVRLELKNSPMKLIAVYPGGMDTDFWPS
EEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
SGKIANTSSFMSADEAAGMLKQALQSTEHGYIADLTIARG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MILISGASSGLGAALAKRYGAEQPICISGRNSERLQLVAKEVSQPCQAQVTDLCDASAVE
CEEEECCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHH
SLFDNLPTTPSLIIHSAGSGYFGPIESQSPEAIKDLLNNNVTSAIFLLREAVKRYKEQNV
HHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
TVVIVMSTAALVPKAEESTYCAAKWAVKGLIESVRLELKNSPMKLIAVYPGGMDTDFWPS
EEEEEEECHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
SGKIANTSSFMSADEAAGMLKQALQSTEHGYIADLTIARG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]