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The map label for this gene is ubiA

Identifier: 157960298

GI number: 157960298

Start: 579168

End: 580034

Strand: Direct

Name: ubiA

Synonym: Spea_0469

Alternate gene names: 157960298

Gene position: 579168-580034 (Clockwise)

Preceding gene: 157960297

Following gene: 157960299

Centisome position: 11.19

GC content: 47.4

Gene sequence:

>867_bases
ATGAATTTAAGGGATAAACTAGACGTTTATATGCGACTCGCGCGTATGGACCGTCCCATTGGTACTTTGTTGTTATTATG
GCCCTGTTTAATGGCCTTAACTTTTGCTGCGGGTGGCTTACCCGATCTAAAGGTGTTTATTATTTTTGTGATTGGCGTAT
TTTCGATGCGGGCTTGCGGCTGCATTATTAACGACTATGCCGATAGAAAGCTCGACGCCCATGTTGAGCGTACCAAAGGT
AGGCCGTTAGCCAGCGGCGAAGTCAGTAGCAAAGAAGCCTTACTACTATTTGTTGTTATGGCACTGTTTTCCTTTGGCTT
AGTGTTAATGCTAAACCCACTCGTGGTGCAGCTATCCGTTATCGGTATCATTCTTACCATCATCTATCCCTTTACTAAAC
GCTATACCAATATGCCGCAGATGTTTCTCGGCACGGTATGGAGCTGGTCCATTCCCATGGCTTATGCCGCGCAAACGGGA
ACGGTTCCGGTCGAGGCCTGGTGGTTATTTGCGGCTAACTGGTGCTGGACGGTGGCATACGACACCATGTATGCCATGGT
GGATCGCGATGACGATTTAAAGGTGGGGATCAAGTCGACGGCGATTCTATTTGGGCGCTATGACAGACAGATTATAGGTC
TATTCCAGCTTGCGGCACTGAGCTGCTTTATTATTGCTGGCATGGTTGCTGATCGCGGCGCTATTTATGCTGTCGGTATC
TTGGCCTTTATCGGTTTTGGCCTGTACCAACAAAAGCTAATCAATGGACGCGAACGGGCACCATGTTTTACCGCTTTTCT
CAATAATAACTGGGCAGGCATGGTGTTATTTACCGCGCTGATGCTGGATTATTTAGTGTTAGGTTAG

Upstream 100 bases:

>100_bases
GCTGTTCTTATTTATCTCGATACTGGTTGAATACTGTTACAGCTCAGTCATAATGCGGTTACAAAATTAAAGGCCGAAGA
CGTTGTAGGAGAGCCTAATC

Downstream 100 bases:

>100_bases
CCCCTCGCTTACTTAGCCCTTAAAAAGCGCCTCTAGCATGAGGCGCTTTTTTTATGCTTAACATTCATCGATATTTAAAT
CTTGCTGTGCTCAATCCAAC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNLRDKLDVYMRLARMDRPIGTLLLLWPCLMALTFAAGGLPDLKVFIIFVIGVFSMRACGCIINDYADRKLDAHVERTKG
RPLASGEVSSKEALLLFVVMALFSFGLVLMLNPLVVQLSVIGIILTIIYPFTKRYTNMPQMFLGTVWSWSIPMAYAAQTG
TVPVEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRYDRQIIGLFQLAALSCFIIAGMVADRGAIYAVGI
LAFIGFGLYQQKLINGRERAPCFTAFLNNNWAGMVLFTALMLDYLVLG

Sequences:

>Translated_288_residues
MNLRDKLDVYMRLARMDRPIGTLLLLWPCLMALTFAAGGLPDLKVFIIFVIGVFSMRACGCIINDYADRKLDAHVERTKG
RPLASGEVSSKEALLLFVVMALFSFGLVLMLNPLVVQLSVIGIILTIIYPFTKRYTNMPQMFLGTVWSWSIPMAYAAQTG
TVPVEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRYDRQIIGLFQLAALSCFIIAGMVADRGAIYAVGI
LAFIGFGLYQQKLINGRERAPCFTAFLNNNWAGMVLFTALMLDYLVLG
>Mature_288_residues
MNLRDKLDVYMRLARMDRPIGTLLLLWPCLMALTFAAGGLPDLKVFIIFVIGVFSMRACGCIINDYADRKLDAHVERTKG
RPLASGEVSSKEALLLFVVMALFSFGLVLMLNPLVVQLSVIGIILTIIYPFTKRYTNMPQMFLGTVWSWSIPMAYAAQTG
TVPVEAWWLFAANWCWTVAYDTMYAMVDRDDDLKVGIKSTAILFGRYDRQIIGLFQLAALSCFIIAGMVADRGAIYAVGI
LAFIGFGLYQQKLINGRERAPCFTAFLNNNWAGMVLFTALMLDYLVLG

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=282, Percent_Identity=31.9148936170213, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=54.4483985765125, Blast_Score=298, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17553718, Length=284, Percent_Identity=34.1549295774648, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32565247, Length=290, Percent_Identity=33.448275862069, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17553720, Length=189, Percent_Identity=38.6243386243386, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=41.8439716312057, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=41.4285714285714, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324370, Length=298, Percent_Identity=30.2013422818792, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21355567, Length=285, Percent_Identity=38.9473684210526, Blast_Score=176, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_SHEPA (A8GZR0)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001500332.1
- STRING:   A8GZR0
- GeneID:   5660869
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_0469
- NMPDR:   fig|398579.3.peg.424
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- ProtClustDB:   PRK12848
- BioCyc:   SPEA398579:SPEA_0469-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 32197; Mature: 32197

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12c35aec)-; HASH(0x1897396c)-; HASH(0x17346cdc)-; HASH(0x17a37edc)-; HASH(0x17a1ce14)-; HASH(0x18132d48)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA