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The map label for this gene is yciR [C]

Identifier: 157960295

GI number: 157960295

Start: 573816

End: 575906

Strand: Reverse

Name: yciR [C]

Synonym: Spea_0466

Alternate gene names: 157960295

Gene position: 575906-573816 (Counterclockwise)

Preceding gene: 157960300

Following gene: 157960290

Centisome position: 11.13

GC content: 45.29

Gene sequence:

>2091_bases
ATGCAAATCAGCAAAAAAATTTCAAAAAATCCATGGCTCCTTTGCCTTCTTATGACGATTTTAACCGTTGCACTGGGTAT
GCTTTGGATATTTAGCTCTCCATCACAATCCCCTGAAATCCAGATCATTATCCCCTTACTCTTATTGGCTAATGTCGCAC
TCCTCGGCACGCTTTGGCTGCATTTTTATCACCAGCCCTCCCAGATACAAGAGCTAGATGACGAGAGCTCGACTGACATT
GGACAATCCGCTAACGCTCGCTCTAATATCGCTAAGTTCCACTCATTAAAGCAATTAAAAGAAAAGCGAGAACAATGCAG
TAAACACAAGCAGTTCAAAACTGTTCAGGAGCAGAACCAAGAGAAAAACCAAGAGGAAATGCAGACAAATGATCCACTGC
TTAAGGCTGTTTTAGAGTCGGCAGCGGTTGCCATTTATGCCATCGACGATAAAGGAAAGTGCATTTTTGCCAACCCGATA
TGTGCTCAATTACTCGGATACACCAGCCCAGAGCAACTACTGAACTTCAATATGCACGAGCTGATCTATCAAAACCACTC
TTGCACAGAAGCAACGCTTCCACTCAGTAATGGAGAGGTTAAAGAGGATATTTTTTGGCGAGCCGACGGCAGTAGCTTCC
CTGTTGATTACAAATCACAACCTCTAGTACTACAGCACAACAGAAACGGTGCGGTGATCTCTTTTTATGACAATAGTGAG
CGTCTCGAAGCGGAAGCACTTATTCGCCATCAAGCCCACTACGATACCTTAACTGAGCTACCTAACAGATTTTTAGCGCT
AAAACGACTCGAACAATTAGTCGAAGCTAGTGAGAGAAGCGGTCAGATGATTGCAGTTATCTTTCTCGATTTAGATGACT
TTAAGAAGATTAATGATTCCTTAGGCCATGAAGCAGGTGACCAACTACTGATCAGTGCATCAAAGCGCTTGCTGAATGCC
ACCCGATCCGAAGATACCGTTGGCCGTTTAGGAGGCGATGAATTTATCATATTGCTGGATGGTCTATCGAGCGCTAGCGA
CGCCCAACCCCTAGCCGAGAATCTCATTGGCGGCTTTAGAAAGCCTTTCTATATCGATAATCGGCAGCTAGTGCTTACCG
CCAGTATTGGTATCGCCATCTACCCTAATGACGGCGAAACATCATCAGAGCTGTTACGAAATGCCGACTCGGCCATGTAT
CACACCAAAAGTATTGGCCGAAATACCTACTCCTACTTCACCCATGCGATGAATAAAGAGGTATCACGCCGCCTTGCGAT
TGAAGAGCAGATCCACGGAGCCTTAGAACGGGGAGAGCTACAAGCTCACTTTCAAATTCAACTCGATATCCGAGATGGCA
GTATCATGGGGGCCGAAGCCCTGCTACGTTGGAATAATCCAACCCTAGGGAACGTATCACCTGCCGAGTTCATTCCTATT
GCCGAGCAAACAGGAGTGATTGAGCCAATGGGAGAGTTTATTCTTAAATGCGCGCTAGAGGCTGCACGCACCTGGCAGAA
GTTGTTTAATGACAAGTTTCGAGTCGCCATTAACCTTTCACCAAGACAGTTTAGAAATCCAAATCTGGTCCAGCTCATTA
CAGATCAAGTTTACAAATTTGGCATGCGCCCCGATGATCTAGAACTTGAAATTACCGAAGGTGTACTGCTGAGTGGCCAC
GCCTATACTTTGGATGCCCTTAAGCAACTAAGCAATGCGGGTTTTTGTATCTCAATGGATGATTTTGGTACTGGTTACTC
CTCACTAAGCTACTTAAGAACCTATCCGTTCCAGATCCTCAAGATTGATCGCAGCTTCATTAGTGATATGAACAAAGACG
GTAAGAGTAACGAGCTGATCATCGCTACTATCGAGATGGCTCACGCTTTGGGGATCAGAGTCATTGCCGAAGGGGTCGAG
ACTCAAGAGCAATTAGATGAGCTTAGCTTTATGATGTGTGATTATGCTCAAGGCTTTCTAATCAGTAAGGCGGTACCTCT
AACTGAGTTGCTCAAAATAGGTACTCACTACAAAGAGCTCCACGAAAACTTAGCGACTCAAGAGTTGCCGATCCCACTGA
CAGCTATGTAG

Upstream 100 bases:

>100_bases
TCCTTCAGATCGCAATCAGCTTACTCTCATGAACTCGCTTAAGCCGACTTCGTTTAGCCAAAAGAGATAAAGTTTCATTA
TCAAACTCTGGATGTGATGC

Downstream 100 bases:

>100_bases
GCTTACAACGATACCATCATAGCTAAGACAGTCTTTCACCCTCTGTTTTTGTACCTTAGATAGTTTTGAAAGTGTCGAGA
GTAAATGTTGATATTCGCAA

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MQISKKISKNPWLLCLLMTILTVALGMLWIFSSPSQSPEIQIIIPLLLLANVALLGTLWLHFYHQPSQIQELDDESSTDI
GQSANARSNIAKFHSLKQLKEKREQCSKHKQFKTVQEQNQEKNQEEMQTNDPLLKAVLESAAVAIYAIDDKGKCIFANPI
CAQLLGYTSPEQLLNFNMHELIYQNHSCTEATLPLSNGEVKEDIFWRADGSSFPVDYKSQPLVLQHNRNGAVISFYDNSE
RLEAEALIRHQAHYDTLTELPNRFLALKRLEQLVEASERSGQMIAVIFLDLDDFKKINDSLGHEAGDQLLISASKRLLNA
TRSEDTVGRLGGDEFIILLDGLSSASDAQPLAENLIGGFRKPFYIDNRQLVLTASIGIAIYPNDGETSSELLRNADSAMY
HTKSIGRNTYSYFTHAMNKEVSRRLAIEEQIHGALERGELQAHFQIQLDIRDGSIMGAEALLRWNNPTLGNVSPAEFIPI
AEQTGVIEPMGEFILKCALEAARTWQKLFNDKFRVAINLSPRQFRNPNLVQLITDQVYKFGMRPDDLELEITEGVLLSGH
AYTLDALKQLSNAGFCISMDDFGTGYSSLSYLRTYPFQILKIDRSFISDMNKDGKSNELIIATIEMAHALGIRVIAEGVE
TQEQLDELSFMMCDYAQGFLISKAVPLTELLKIGTHYKELHENLATQELPIPLTAM

Sequences:

>Translated_696_residues
MQISKKISKNPWLLCLLMTILTVALGMLWIFSSPSQSPEIQIIIPLLLLANVALLGTLWLHFYHQPSQIQELDDESSTDI
GQSANARSNIAKFHSLKQLKEKREQCSKHKQFKTVQEQNQEKNQEEMQTNDPLLKAVLESAAVAIYAIDDKGKCIFANPI
CAQLLGYTSPEQLLNFNMHELIYQNHSCTEATLPLSNGEVKEDIFWRADGSSFPVDYKSQPLVLQHNRNGAVISFYDNSE
RLEAEALIRHQAHYDTLTELPNRFLALKRLEQLVEASERSGQMIAVIFLDLDDFKKINDSLGHEAGDQLLISASKRLLNA
TRSEDTVGRLGGDEFIILLDGLSSASDAQPLAENLIGGFRKPFYIDNRQLVLTASIGIAIYPNDGETSSELLRNADSAMY
HTKSIGRNTYSYFTHAMNKEVSRRLAIEEQIHGALERGELQAHFQIQLDIRDGSIMGAEALLRWNNPTLGNVSPAEFIPI
AEQTGVIEPMGEFILKCALEAARTWQKLFNDKFRVAINLSPRQFRNPNLVQLITDQVYKFGMRPDDLELEITEGVLLSGH
AYTLDALKQLSNAGFCISMDDFGTGYSSLSYLRTYPFQILKIDRSFISDMNKDGKSNELIIATIEMAHALGIRVIAEGVE
TQEQLDELSFMMCDYAQGFLISKAVPLTELLKIGTHYKELHENLATQELPIPLTAM
>Mature_696_residues
MQISKKISKNPWLLCLLMTILTVALGMLWIFSSPSQSPEIQIIIPLLLLANVALLGTLWLHFYHQPSQIQELDDESSTDI
GQSANARSNIAKFHSLKQLKEKREQCSKHKQFKTVQEQNQEKNQEEMQTNDPLLKAVLESAAVAIYAIDDKGKCIFANPI
CAQLLGYTSPEQLLNFNMHELIYQNHSCTEATLPLSNGEVKEDIFWRADGSSFPVDYKSQPLVLQHNRNGAVISFYDNSE
RLEAEALIRHQAHYDTLTELPNRFLALKRLEQLVEASERSGQMIAVIFLDLDDFKKINDSLGHEAGDQLLISASKRLLNA
TRSEDTVGRLGGDEFIILLDGLSSASDAQPLAENLIGGFRKPFYIDNRQLVLTASIGIAIYPNDGETSSELLRNADSAMY
HTKSIGRNTYSYFTHAMNKEVSRRLAIEEQIHGALERGELQAHFQIQLDIRDGSIMGAEALLRWNNPTLGNVSPAEFIPI
AEQTGVIEPMGEFILKCALEAARTWQKLFNDKFRVAINLSPRQFRNPNLVQLITDQVYKFGMRPDDLELEITEGVLLSGH
AYTLDALKQLSNAGFCISMDDFGTGYSSLSYLRTYPFQILKIDRSFISDMNKDGKSNELIIATIEMAHALGIRVIAEGVE
TQEQLDELSFMMCDYAQGFLISKAVPLTELLKIGTHYKELHENLATQELPIPLTAM

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=551, Percent_Identity=31.5789473684211, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI87081921, Length=440, Percent_Identity=30.2272727272727, Blast_Score=212, Evalue=6e-56,
Organism=Escherichia coli, GI226510982, Length=461, Percent_Identity=26.8980477223427, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=35.1239669421488, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87081845, Length=257, Percent_Identity=33.4630350194552, Blast_Score=154, Evalue=3e-38,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=33.7448559670782, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1787055, Length=262, Percent_Identity=34.3511450381679, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1786507, Length=263, Percent_Identity=30.7984790874525, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=33.6, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788381, Length=586, Percent_Identity=26.1092150170648, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=29.3650793650794, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87082096, Length=442, Percent_Identity=23.9819004524887, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=35.1190476190476, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788849, Length=256, Percent_Identity=27.734375, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081977, Length=168, Percent_Identity=33.9285714285714, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=34.1317365269461, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786584, Length=276, Percent_Identity=25, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081881, Length=213, Percent_Identity=30.5164319248826, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=36.3636363636364, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787262, Length=173, Percent_Identity=30.0578034682081, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=31.9277108433735, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787410, Length=151, Percent_Identity=29.8013245033113, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788085, Length=163, Percent_Identity=30.6748466257669, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787816, Length=166, Percent_Identity=30.1204819277108, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI87081974, Length=85, Percent_Identity=38.8235294117647, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 78189; Mature: 78189

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISKKISKNPWLLCLLMTILTVALGMLWIFSSPSQSPEIQIIIPLLLLANVALLGTLWL
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
HFYHQPSQIQELDDESSTDIGQSANARSNIAKFHSLKQLKEKREQCSKHKQFKTVQEQNQ
HHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKNQEEMQTNDPLLKAVLESAAVAIYAIDDKGKCIFANPICAQLLGYTSPEQLLNFNMHE
HCCHHHHHCCCHHHHHHHHHCEEEEEEECCCCCEEEECHHHHHHHCCCCHHHHHCCCHHH
LIYQNHSCTEATLPLSNGEVKEDIFWRADGSSFPVDYKSQPLVLQHNRNGAVISFYDNSE
HHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCC
RLEAEALIRHQAHYDTLTELPNRFLALKRLEQLVEASERSGQMIAVIFLDLDDFKKINDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHH
LGHEAGDQLLISASKRLLNATRSEDTVGRLGGDEFIILLDGLSSASDAQPLAENLIGGFR
HCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCC
KPFYIDNRQLVLTASIGIAIYPNDGETSSELLRNADSAMYHTKSIGRNTYSYFTHAMNKE
CCEEECCCEEEEEEEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHH
VSRRLAIEEQIHGALERGELQAHFQIQLDIRDGSIMGAEALLRWNNPTLGNVSPAEFIPI
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCEECCHHHEEECCCCCCCCCHHHEECC
AEQTGVIEPMGEFILKCALEAARTWQKLFNDKFRVAINLSPRQFRNPNLVQLITDQVYKF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHC
GMRPDDLELEITEGVLLSGHAYTLDALKQLSNAGFCISMDDFGTGYSSLSYLRTYPFQIL
CCCCCCCEEEEECCEEECCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHHEE
KIDRSFISDMNKDGKSNELIIATIEMAHALGIRVIAEGVETQEQLDELSFMMCDYAQGFL
EHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHH
ISKAVPLTELLKIGTHYKELHENLATQELPIPLTAM
HHCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQISKKISKNPWLLCLLMTILTVALGMLWIFSSPSQSPEIQIIIPLLLLANVALLGTLWL
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
HFYHQPSQIQELDDESSTDIGQSANARSNIAKFHSLKQLKEKREQCSKHKQFKTVQEQNQ
HHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKNQEEMQTNDPLLKAVLESAAVAIYAIDDKGKCIFANPICAQLLGYTSPEQLLNFNMHE
HCCHHHHHCCCHHHHHHHHHCEEEEEEECCCCCEEEECHHHHHHHCCCCHHHHHCCCHHH
LIYQNHSCTEATLPLSNGEVKEDIFWRADGSSFPVDYKSQPLVLQHNRNGAVISFYDNSE
HHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCC
RLEAEALIRHQAHYDTLTELPNRFLALKRLEQLVEASERSGQMIAVIFLDLDDFKKINDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHH
LGHEAGDQLLISASKRLLNATRSEDTVGRLGGDEFIILLDGLSSASDAQPLAENLIGGFR
HCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCC
KPFYIDNRQLVLTASIGIAIYPNDGETSSELLRNADSAMYHTKSIGRNTYSYFTHAMNKE
CCEEECCCEEEEEEEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHH
VSRRLAIEEQIHGALERGELQAHFQIQLDIRDGSIMGAEALLRWNNPTLGNVSPAEFIPI
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCEECCHHHEEECCCCCCCCCHHHEECC
AEQTGVIEPMGEFILKCALEAARTWQKLFNDKFRVAINLSPRQFRNPNLVQLITDQVYKF
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHC
GMRPDDLELEITEGVLLSGHAYTLDALKQLSNAGFCISMDDFGTGYSSLSYLRTYPFQIL
CCCCCCCEEEEECCEEECCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHHEE
KIDRSFISDMNKDGKSNELIIATIEMAHALGIRVIAEGVETQEQLDELSFMMCDYAQGFL
EHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHH
ISKAVPLTELLKIGTHYKELHENLATQELPIPLTAM
HHCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]