Click here to switch to the map view.

The map label for this gene is yggB [C]

Identifier: 157960286

GI number: 157960286

Start: 566318

End: 567154

Strand: Reverse

Name: yggB [C]

Synonym: Spea_0457

Alternate gene names: 157960286

Gene position: 567154-566318 (Counterclockwise)

Preceding gene: 157960288

Following gene: 157960285

Centisome position: 10.96

GC content: 43.37

Gene sequence:

>837_bases
ATGAATGAGCAAGGCCTAGACCAAGAGATCGCACAACTGCAAAACGCTTACACCGCCATCACCGAATTTCTGGTGCAATA
TAGCTTTAGTATTCTAGGTGCCATCATTATCTTCCTGATTGGTCTATGGCTAGCAGCCAAAGCGGCTAACCTTGTCACGC
GTATTTTTGAAAAGCACGAGATAGATATCACCCTCAGTAACTTTACCAGCAACTTCGTGCGCATCTTAGTTATTGTGATG
GTAGGTATTATTGCCTTAGGCAAGTTGGGGATCAGTGTCACCCCTATGGTCGCAGCAATAGGTGCAGCCTCTCTAGGTGC
AGGTTTGGCATTACAGGGCATGTTAGCTAACTACGCGGCTGGCATTACCATTATTGTCACTCGACCTTTTATTGTGGGTA
ACACCATCGAGATAAAAGGAGTTGGCGGATTAGTTAAAAATATCCACCTCGGTATGACGGTGCTGACTAACGAAGAGGGA
GAGGAGATCAACATCCCCAATAAGCATATTGTCGGCGAGATCTTACATAACTCTTTTGCCAATAAACTGGTCGAAACCAA
GTTTAATATCAGTTATCAGTCTAATACTGACGAAGTGGTAGGCATGTTAGCTAAAGTACTAGCCGATAGCCCTAGAGTCT
TTGAAGGCGATAAAGCCCAAGTCGGTATCAATGACTTTAATAGTATAGGTATTGAAATAGGCATTCGTTACTGGGTGTCT
ACCGACACTTACTTTCAAGACAAGTACCAAACTAATGCCGAACTATTTAAAGCATTAAAACAGGCGAATATCGAGATCCC
TTGCCCGGTAAAACAGATCCATATCCAAGAGCACTAA

Upstream 100 bases:

>100_bases
AAATGTCCTCATAGCAGCTCACAACTGCGCAAAAACTGAGTTACAAAACTGTTTATTTTCAGTAAGCTAATTGATAAAGG
TTGTCATAGAGGATAGATCC

Downstream 100 bases:

>100_bases
CCTGATCGATACTTAGCGGTGCCCTATATCCGCTAAGTATTCATTTTATTCATCATCCAAATCACTTATATCAAAAGCCT
GCAACCTCGCGTTTTGTCGC

Product: mechanosensitive ion channel protein MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MNEQGLDQEIAQLQNAYTAITEFLVQYSFSILGAIIIFLIGLWLAAKAANLVTRIFEKHEIDITLSNFTSNFVRILVIVM
VGIIALGKLGISVTPMVAAIGAASLGAGLALQGMLANYAAGITIIVTRPFIVGNTIEIKGVGGLVKNIHLGMTVLTNEEG
EEINIPNKHIVGEILHNSFANKLVETKFNISYQSNTDEVVGMLAKVLADSPRVFEGDKAQVGINDFNSIGIEIGIRYWVS
TDTYFQDKYQTNAELFKALKQANIEIPCPVKQIHIQEH

Sequences:

>Translated_278_residues
MNEQGLDQEIAQLQNAYTAITEFLVQYSFSILGAIIIFLIGLWLAAKAANLVTRIFEKHEIDITLSNFTSNFVRILVIVM
VGIIALGKLGISVTPMVAAIGAASLGAGLALQGMLANYAAGITIIVTRPFIVGNTIEIKGVGGLVKNIHLGMTVLTNEEG
EEINIPNKHIVGEILHNSFANKLVETKFNISYQSNTDEVVGMLAKVLADSPRVFEGDKAQVGINDFNSIGIEIGIRYWVS
TDTYFQDKYQTNAELFKALKQANIEIPCPVKQIHIQEH
>Mature_278_residues
MNEQGLDQEIAQLQNAYTAITEFLVQYSFSILGAIIIFLIGLWLAAKAANLVTRIFEKHEIDITLSNFTSNFVRILVIVM
VGIIALGKLGISVTPMVAAIGAASLGAGLALQGMLANYAAGITIIVTRPFIVGNTIEIKGVGGLVKNIHLGMTVLTNEEG
EEINIPNKHIVGEILHNSFANKLVETKFNISYQSNTDEVVGMLAKVLADSPRVFEGDKAQVGINDFNSIGIEIGIRYWVS
TDTYFQDKYQTNAELFKALKQANIEIPCPVKQIHIQEH

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=258, Percent_Identity=29.8449612403101, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786670, Length=190, Percent_Identity=28.4210526315789, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367355, Length=209, Percent_Identity=23.9234449760766, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 30345; Mature: 30345

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQGLDQEIAQLQNAYTAITEFLVQYSFSILGAIIIFLIGLWLAAKAANLVTRIFEKHE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDITLSNFTSNFVRILVIVMVGIIALGKLGISVTPMVAAIGAASLGAGLALQGMLANYAA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GITIIVTRPFIVGNTIEIKGVGGLVKNIHLGMTVLTNEEGEEINIPNKHIVGEILHNSFA
CEEEEEECCEEECCEEEEEECCHHHHHHHCCEEEEECCCCCEECCCCHHHHHHHHHHHHH
NKLVETKFNISYQSNTDEVVGMLAKVLADSPRVFEGDKAQVGINDFNSIGIEIGIRYWVS
HHHHHHHEEEEECCCHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCCEEEEEEEEEEE
TDTYFQDKYQTNAELFKALKQANIEIPCPVKQIHIQEH
CCCEEHHHHCCCHHHHHHHHHCCCCCCCCHHHEEECCC
>Mature Secondary Structure
MNEQGLDQEIAQLQNAYTAITEFLVQYSFSILGAIIIFLIGLWLAAKAANLVTRIFEKHE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IDITLSNFTSNFVRILVIVMVGIIALGKLGISVTPMVAAIGAASLGAGLALQGMLANYAA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GITIIVTRPFIVGNTIEIKGVGGLVKNIHLGMTVLTNEEGEEINIPNKHIVGEILHNSFA
CEEEEEECCEEECCEEEEEECCHHHHHHHCCEEEEECCCCCEECCCCHHHHHHHHHHHHH
NKLVETKFNISYQSNTDEVVGMLAKVLADSPRVFEGDKAQVGINDFNSIGIEIGIRYWVS
HHHHHHHEEEEECCCHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCCEEEEEEEEEEE
TDTYFQDKYQTNAELFKALKQANIEIPCPVKQIHIQEH
CCCEEHHHHCCCHHHHHHHHHCCCCCCCCHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]