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The map label for this gene is nahR [H]

Identifier: 157960283

GI number: 157960283

Start: 562872

End: 563810

Strand: Reverse

Name: nahR [H]

Synonym: Spea_0454

Alternate gene names: 157960283

Gene position: 563810-562872 (Counterclockwise)

Preceding gene: 157960284

Following gene: 157960281

Centisome position: 10.9

GC content: 47.18

Gene sequence:

>939_bases
ATGAATCCAACTGACTTAAAAATTATTCAACAGTGCGACCTCAACTTATTGCTGAGCCTAGCTATTCTAATTGAGGAACA
GAGCGTATCTAAGAGTGCAGACAGGCTAGACATATCCCAGCCTGCCATGAGCCAAAACTTGAAGAAGTTGCGCACTATGT
TCGATGACCCCCTTTTTGTAAAACAGGGCCAAGGCATTCGTGCGACTAGCAAGGCATTGAGATTATATGGCTCACTCACA
GAGTGGCTGCAGATGAGCGATCGACTGATCTCGCAGACCGCTTTCGATCCGATGGAAAGTCACGGGGTGATCCGCATTGC
ATTTATGGATGACCTCACCCAGAGCATGATCCCTATTATGCTAGACAAGATCCTCACTTTTGCGCCCAATGTAGAACTTG
AGTTTGTGCACAAGCCTAGAGATGTATTTTCTTTACTCGAGTCAGGCGAAATTGATATTGCCGCTGCGGGAACTGACACA
CCACCCGCAAATATTCATGGCCGCCATATCAGCACAGATAATTACTGCGCCGCCTATAGCTTAACGCATCCCTTAGCAAA
AATTGCACAGCCAACGCTGGCGCAGATTTTCGCTTATGATACTGCCGAATATTCAGCTTCAAACCTAGTCGAGCAGGAAA
TCACCCAGTTAGCATTGCAGAATCAATTGCAACGCAAGATCACCTTTGCGACAGGCTCGTTTCTAGTCTTGCTGCAGGGG
TTACTCAGCGGAAAACACGTAGGCTTTTTGCCCCAACGTGTACTCAATTCCGAGAAGTGGCGTTCACAATTAAAGGGAGT
CGTACTCACCGAGCTCCCCCAGCTAGACAGTACCCTTTATTGGCACGCAAGAGTGCACAAAGATCCATTGATCCAATGGT
TTAAAGATCAATGCTTGGATATTGTCAGCCAACTACAGCTGCAAAGCGGCAACTCCTGA

Upstream 100 bases:

>100_bases
TCTGTTGGGATCGTCACCAAAGAGCCCCTGAACTACAGCAGTGGTTTAGACGTCAATTGGTCACGCTTTTTCACAAACAC
TTTCCTTTAAAACAAGTCCT

Downstream 100 bases:

>100_bases
GTCAACAGGCTCAATTTAAAGCCCTCTTTGCCACTCTTGCCGTAACTGAATTTGCTCAGGCGTGTTCATTGCAGCCTCTA
CTTCTGCCAGCAATGCTTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNPTDLKIIQQCDLNLLLSLAILIEEQSVSKSADRLDISQPAMSQNLKKLRTMFDDPLFVKQGQGIRATSKALRLYGSLT
EWLQMSDRLISQTAFDPMESHGVIRIAFMDDLTQSMIPIMLDKILTFAPNVELEFVHKPRDVFSLLESGEIDIAAAGTDT
PPANIHGRHISTDNYCAAYSLTHPLAKIAQPTLAQIFAYDTAEYSASNLVEQEITQLALQNQLQRKITFATGSFLVLLQG
LLSGKHVGFLPQRVLNSEKWRSQLKGVVLTELPQLDSTLYWHARVHKDPLIQWFKDQCLDIVSQLQLQSGNS

Sequences:

>Translated_312_residues
MNPTDLKIIQQCDLNLLLSLAILIEEQSVSKSADRLDISQPAMSQNLKKLRTMFDDPLFVKQGQGIRATSKALRLYGSLT
EWLQMSDRLISQTAFDPMESHGVIRIAFMDDLTQSMIPIMLDKILTFAPNVELEFVHKPRDVFSLLESGEIDIAAAGTDT
PPANIHGRHISTDNYCAAYSLTHPLAKIAQPTLAQIFAYDTAEYSASNLVEQEITQLALQNQLQRKITFATGSFLVLLQG
LLSGKHVGFLPQRVLNSEKWRSQLKGVVLTELPQLDSTLYWHARVHKDPLIQWFKDQCLDIVSQLQLQSGNS
>Mature_312_residues
MNPTDLKIIQQCDLNLLLSLAILIEEQSVSKSADRLDISQPAMSQNLKKLRTMFDDPLFVKQGQGIRATSKALRLYGSLT
EWLQMSDRLISQTAFDPMESHGVIRIAFMDDLTQSMIPIMLDKILTFAPNVELEFVHKPRDVFSLLESGEIDIAAAGTDT
PPANIHGRHISTDNYCAAYSLTHPLAKIAQPTLAQIFAYDTAEYSASNLVEQEITQLALQNQLQRKITFATGSFLVLLQG
LLSGKHVGFLPQRVLNSEKWRSQLKGVVLTELPQLDSTLYWHARVHKDPLIQWFKDQCLDIVSQLQLQSGNS

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=326, Percent_Identity=26.6871165644172, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790147, Length=310, Percent_Identity=23.8709677419355, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786820, Length=309, Percent_Identity=25.2427184466019, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35004; Mature: 35004

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTDLKIIQQCDLNLLLSLAILIEEQSVSKSADRLDISQPAMSQNLKKLRTMFDDPLFV
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEE
KQGQGIRATSKALRLYGSLTEWLQMSDRLISQTAFDPMESHGVIRIAFMDDLTQSMIPIM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEHHHHHHHHHHHH
LDKILTFAPNVELEFVHKPRDVFSLLESGEIDIAAAGTDTPPANIHGRHISTDNYCAAYS
HHHHHHHCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCEECCCCCEEEHH
LTHPLAKIAQPTLAQIFAYDTAEYSASNLVEQEITQLALQNQLQRKITFATGSFLVLLQG
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LLSGKHVGFLPQRVLNSEKWRSQLKGVVLTELPQLDSTLYWHARVHKDPLIQWFKDQCLD
HHCCCCCCCCHHHHHCHHHHHHHHCCCHHHHCCCCCCCEEEEEHHCCCHHHHHHHHHHHH
IVSQLQLQSGNS
HHHHHHHCCCCC
>Mature Secondary Structure
MNPTDLKIIQQCDLNLLLSLAILIEEQSVSKSADRLDISQPAMSQNLKKLRTMFDDPLFV
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEE
KQGQGIRATSKALRLYGSLTEWLQMSDRLISQTAFDPMESHGVIRIAFMDDLTQSMIPIM
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEHHHHHHHHHHHH
LDKILTFAPNVELEFVHKPRDVFSLLESGEIDIAAAGTDTPPANIHGRHISTDNYCAAYS
HHHHHHHCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCEECCCCCEEEHH
LTHPLAKIAQPTLAQIFAYDTAEYSASNLVEQEITQLALQNQLQRKITFATGSFLVLLQG
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LLSGKHVGFLPQRVLNSEKWRSQLKGVVLTELPQLDSTLYWHARVHKDPLIQWFKDQCLD
HHCCCCCCCCHHHHHCHHHHHHHHCCCHHHHCCCCCCCEEEEEHHCCCHHHHHHHHHHHH
IVSQLQLQSGNS
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]