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The map label for this gene is dsbA [H]

Identifier: 157960264

GI number: 157960264

Start: 541687

End: 542343

Strand: Direct

Name: dsbA [H]

Synonym: Spea_0435

Alternate gene names: 157960264

Gene position: 541687-542343 (Clockwise)

Preceding gene: 157960263

Following gene: 157960265

Centisome position: 10.47

GC content: 46.58

Gene sequence:

>657_bases
ATGATCAAAATTCTAGTCACATTATTTCTCGTTCTAGCAATGAGTGCCTGTTCAGAACCCTCTCATCTAGGCAGTGACGG
TAACTACGTCGCAGGTGTGCATTACCGTGAATTAGCGACCCCGATCCCAGCTAGTGGTGATGATATCTCGGTGACAGAGT
TTTTCTGGTATGGCTGCCCACATTGTGAGCTGTTTGAAAAGCCACTACACAAATGGCAGCAAACCATGGCTGATGGAGTC
GTGCTTGTGCAGTCACCTGCAGTATGGAATGAGGCGATGAAGCTGCATGCCAAGGTATTCTTTATCGTGCAGCAGATGCC
AGACAAGCAAAAGATCCATGCGGCTCTGTTTAATGAGATTGTTGGACTGCGTGAGATAACCGATCTGGATGAGCAGCAGG
CTAAGCTTAGTGATTTTTTAGCGGGCTATGGCCTAAGCGAGCAAGCGTTTAACGACAAGCTTAATTCGGCCGATATTATT
TCCAAGCTTAAGCAGGCGATGCTACTCATGTCGTCGGCAGGGATCCAAGGCACGCCAACCATCTTAGTTAATGGTCGCTA
TATTATTCTCAATGAGTCGGCAAACTCAGCAGAACAAGTGATGGATATTGCCAGTTACTTGGTTGAGCTTGAAAGGCAAA
ATTTGTTAGCCATGTAG

Upstream 100 bases:

>100_bases
TTAGGGCTAAAATGAGATGAGTAAACGCGATGGAGCTAATCGGTAATAGCCAGCTATATTGTTAAGCACATCGCTAACTA
CGCCAACAAAAGGAGTTGTC

Downstream 100 bases:

>100_bases
ACTCACATAACATTGGTTGTAAGCGTCATGCCTAGTGAAAAAGCCGTAGTGATATTCGATGGTGCTTGCAACCTGTGTGA
TGGCGCTGTGTGTGTTATTA

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIKILVTLFLVLAMSACSEPSHLGSDGNYVAGVHYRELATPIPASGDDISVTEFFWYGCPHCELFEKPLHKWQQTMADGV
VLVQSPAVWNEAMKLHAKVFFIVQQMPDKQKIHAALFNEIVGLREITDLDEQQAKLSDFLAGYGLSEQAFNDKLNSADII
SKLKQAMLLMSSAGIQGTPTILVNGRYIILNESANSAEQVMDIASYLVELERQNLLAM

Sequences:

>Translated_218_residues
MIKILVTLFLVLAMSACSEPSHLGSDGNYVAGVHYRELATPIPASGDDISVTEFFWYGCPHCELFEKPLHKWQQTMADGV
VLVQSPAVWNEAMKLHAKVFFIVQQMPDKQKIHAALFNEIVGLREITDLDEQQAKLSDFLAGYGLSEQAFNDKLNSADII
SKLKQAMLLMSSAGIQGTPTILVNGRYIILNESANSAEQVMDIASYLVELERQNLLAM
>Mature_218_residues
MIKILVTLFLVLAMSACSEPSHLGSDGNYVAGVHYRELATPIPASGDDISVTEFFWYGCPHCELFEKPLHKWQQTMADGV
VLVQSPAVWNEAMKLHAKVFFIVQQMPDKQKIHAALFNEIVGLREITDLDEQQAKLSDFLAGYGLSEQAFNDKLNSADII
SKLKQAMLLMSSAGIQGTPTILVNGRYIILNESANSAEQVMDIASYLVELERQNLLAM

Specific function: Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1348 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023205
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: 5.3.4.1

Molecular weight: Translated: 24176; Mature: 24176

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKILVTLFLVLAMSACSEPSHLGSDGNYVAGVHYRELATPIPASGDDISVTEFFWYGCP
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCHHHHHHCCCC
HCELFEKPLHKWQQTMADGVVLVQSPAVWNEAMKLHAKVFFIVQQMPDKQKIHAALFNEI
CHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VGLREITDLDEQQAKLSDFLAGYGLSEQAFNDKLNSADIISKLKQAMLLMSSAGIQGTPT
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
ILVNGRYIILNESANSAEQVMDIASYLVELERQNLLAM
EEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKILVTLFLVLAMSACSEPSHLGSDGNYVAGVHYRELATPIPASGDDISVTEFFWYGCP
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCHHHHHHCCCC
HCELFEKPLHKWQQTMADGVVLVQSPAVWNEAMKLHAKVFFIVQQMPDKQKIHAALFNEI
CHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VGLREITDLDEQQAKLSDFLAGYGLSEQAFNDKLNSADIISKLKQAMLLMSSAGIQGTPT
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
ILVNGRYIILNESANSAEQVMDIASYLVELERQNLLAM
EEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10051655 [H]