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The map label for this gene is fis [H]

Identifier: 157960218

GI number: 157960218

Start: 471188

End: 471493

Strand: Reverse

Name: fis [H]

Synonym: Spea_0389

Alternate gene names: 157960218

Gene position: 471493-471188 (Counterclockwise)

Preceding gene: 157960219

Following gene: 157960217

Centisome position: 9.11

GC content: 44.77

Gene sequence:

>306_bases
ATGTTTGATCAGACTACTCACACTGAAGTTCACCCACTTACTGTTGGCAAAATCGAAACCGCAAGTGGTGCAATCAAGCC
ACAACTACTACGTGATGCGGTAAAGCGTGCTGTCACTAACTTTTTCGCTCAGATGGACGGGCAAGAAGCTGAAGAAGTAT
ATGAAATGGTGTTAAGCGAAGTTGAAGCACCTCTGCTAGATATCATCATGCAACACACTCGTGGCAACCAAACTCGCGCT
GCCAACATGCTAGGTATCAACCGTGGTACACTACGCAAGAAATTAAAGAAATACGGCATGAACTAA

Upstream 100 bases:

>100_bases
GAGCCGAGTTTAATCGACTCGAAACCGTTGAAGAACAATGTTCCATGGTGGAACGCTATTTTGATGAATTTGTTGCATAT
TAATAAAGAGCAGAATACGA

Downstream 100 bases:

>100_bases
GACTAACGTCTTAACGTGTTGTATTAAAACGGGCTTTCCAGCAATGGAAAGCCCGTTTTGCTTTATATGTACCCTCATAT
GTACCCCGCCCTTACTTCCC

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MFDQTTHTEVHPLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSEVEAPLLDIIMQHTRGNQTRA
ANMLGINRGTLRKKLKKYGMN

Sequences:

>Translated_101_residues
MFDQTTHTEVHPLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSEVEAPLLDIIMQHTRGNQTRA
ANMLGINRGTLRKKLKKYGMN
>Mature_101_residues
MFDQTTHTEVHPLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSEVEAPLLDIIMQHTRGNQTRA
ANMLGINRGTLRKKLKKYGMN

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters [H]

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=102, Percent_Identity=59.8039215686275, Blast_Score=125, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 11344; Mature: 11344

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDQTTHTEVHPLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
HCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFDQTTHTEVHPLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
HCHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA