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The map label for this gene is hemY [H]

Identifier: 157960199

GI number: 157960199

Start: 448956

End: 450125

Strand: Reverse

Name: hemY [H]

Synonym: Spea_0370

Alternate gene names: 157960199

Gene position: 450125-448956 (Counterclockwise)

Preceding gene: 157960200

Following gene: 157960198

Centisome position: 8.7

GC content: 45.04

Gene sequence:

>1170_bases
ATGGTCAGAGCGCTCGTCTATCTTGTCATTATCTTATTAGGACTGTGCATCAGTCCTTTTCTTGTGGGCAGCAAAGGCTA
CCTTTATCTAGCGATTGGCGACTATCAGGTTGAAACTAGTATCTTTTTTGCCGTCATTGCACTCATCATCTTTTACAGCT
TATTGCAGTTAGTTGAGTTCGTTGTTGTTTGGCTATTAAACATGGTACTCAGTAGCCGCTACCTTCCTGAAAGATGGCGC
AAAAAAGCAGCAAGAAAACACACCCTTCTTGGCGCACTAGCGTTAGCGGAAGAAGACTGGCTTGCTGCCGAAAAAGCCAT
GGCAAAAGGTGCAGAGAAAGGTGAGATCCCAGCGCTTAACTTACTCGCCGCAGCTCGAGCCGCGCACCATCAAGATAACC
ACCAAGCCCGTGATGAATATCTCGCTAAGGCGCAACTAGAACCGCTAGCCGCTAAAGCGGTAGGTACCACTCGTACTCGT
TATTTATTGCAACAAGGTGACTTAATCGCCGCGAGAGAAGAGTTAGATAAGCTTAATCCGACCAGTAAGAGTAAGTTACC
TGTGCTCAAGCTAGCTATAGAGCTTTATCAGGCACAACAAGATTGGCAGGCGCTGAAGTTACTACTACCTATCGTGAGTA
AAAAACAAATCCTGGCCGATGACGCACTCCAAGCCTTGTCGTTAAAAACCAATCTGGCGCTATTAACTCAAGCCGCTAAA
GCTAACGAGCAAGAGCTAGAAAAGTGCTGGCACTGGCTCTCTCGAGCTGAAAGAAAACAAGCTGAATATATTGCACTCTA
TGCCATTGGATTGAGCCGTTTTGAACGAAAAGATGAAGCGGTGAAGATGTTACTTAAGCAAGTAAAAACCTCTGCCTCGC
CATCCATTTTTAAGGCTGTAGCCGAAGTGCTAACACCAGCAGATGTTGAAGCTAAAAAGCAGTTGCTTGCCTTAGAAACT
CAATTTGAAAATAACGTCGACTATCAAACATGCTTAGCTAAGCTGTATCAGCAAAATCATGATTATCACCAAGCTAAAAT
CTGGTGGCAAAAGGCCTGTTATCTACAAGATGACAAGAATAGTTTGCATGCTCTCGCTGATGCCCAAGAGCACTTGGGTG
AGCTTAACAGAGCGTTACAATCCAGACGTAATGCGGCTAAACTCGGTTAG

Upstream 100 bases:

>100_bases
CACTGAAGATCCAAACGACCAGTATTGAACGCTTCGAAGCATCTAATTTACTTAATCAGTTAGTCACTTACGGCAACTTG
ATGACAGAGGAGGCGCAGTA

Downstream 100 bases:

>100_bases
CACTTATACTTTTTTAAACTAAAGGTCGTCTTTTTGGCGGCCTTTTTTTATTTAGCGAAACAGCTCTATCATTTAAAAGT
ATTCTAAGCACCTGATAATA

Product: HemY domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MVRALVYLVIILLGLCISPFLVGSKGYLYLAIGDYQVETSIFFAVIALIIFYSLLQLVEFVVVWLLNMVLSSRYLPERWR
KKAARKHTLLGALALAEEDWLAAEKAMAKGAEKGEIPALNLLAAARAAHHQDNHQARDEYLAKAQLEPLAAKAVGTTRTR
YLLQQGDLIAAREELDKLNPTSKSKLPVLKLAIELYQAQQDWQALKLLLPIVSKKQILADDALQALSLKTNLALLTQAAK
ANEQELEKCWHWLSRAERKQAEYIALYAIGLSRFERKDEAVKMLLKQVKTSASPSIFKAVAEVLTPADVEAKKQLLALET
QFENNVDYQTCLAKLYQQNHDYHQAKIWWQKACYLQDDKNSLHALADAQEHLGELNRALQSRRNAAKLG

Sequences:

>Translated_389_residues
MVRALVYLVIILLGLCISPFLVGSKGYLYLAIGDYQVETSIFFAVIALIIFYSLLQLVEFVVVWLLNMVLSSRYLPERWR
KKAARKHTLLGALALAEEDWLAAEKAMAKGAEKGEIPALNLLAAARAAHHQDNHQARDEYLAKAQLEPLAAKAVGTTRTR
YLLQQGDLIAAREELDKLNPTSKSKLPVLKLAIELYQAQQDWQALKLLLPIVSKKQILADDALQALSLKTNLALLTQAAK
ANEQELEKCWHWLSRAERKQAEYIALYAIGLSRFERKDEAVKMLLKQVKTSASPSIFKAVAEVLTPADVEAKKQLLALET
QFENNVDYQTCLAKLYQQNHDYHQAKIWWQKACYLQDDKNSLHALADAQEHLGELNRALQSRRNAAKLG
>Mature_389_residues
MVRALVYLVIILLGLCISPFLVGSKGYLYLAIGDYQVETSIFFAVIALIIFYSLLQLVEFVVVWLLNMVLSSRYLPERWR
KKAARKHTLLGALALAEEDWLAAEKAMAKGAEKGEIPALNLLAAARAAHHQDNHQARDEYLAKAQLEPLAAKAVGTTRTR
YLLQQGDLIAAREELDKLNPTSKSKLPVLKLAIELYQAQQDWQALKLLLPIVSKKQILADDALQALSLKTNLALLTQAAK
ANEQELEKCWHWLSRAERKQAEYIALYAIGLSRFERKDEAVKMLLKQVKTSASPSIFKAVAEVLTPADVEAKKQLLALET
QFENNVDYQTCLAKLYQQNHDYHQAKIWWQKACYLQDDKNSLHALADAQEHLGELNRALQSRRNAAKLG

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790234, Length=381, Percent_Identity=25.9842519685039, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07219 HemY_N [H]

EC number: NA

Molecular weight: Translated: 43838; Mature: 43838

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRALVYLVIILLGLCISPFLVGSKGYLYLAIGDYQVETSIFFAVIALIIFYSLLQLVEF
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
VVVWLLNMVLSSRYLPERWRKKAARKHTLLGALALAEEDWLAAEKAMAKGAEKGEIPALN
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LLAAARAAHHQDNHQARDEYLAKAQLEPLAAKAVGTTRTRYLLQQGDLIAAREELDKLNP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
TSKSKLPVLKLAIELYQAQQDWQALKLLLPIVSKKQILADDALQALSLKTNLALLTQAAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANEQELEKCWHWLSRAERKQAEYIALYAIGLSRFERKDEAVKMLLKQVKTSASPSIFKAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AEVLTPADVEAKKQLLALETQFENNVDYQTCLAKLYQQNHDYHQAKIWWQKACYLQDDKN
HHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCH
SLHALADAQEHLGELNRALQSRRNAAKLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVRALVYLVIILLGLCISPFLVGSKGYLYLAIGDYQVETSIFFAVIALIIFYSLLQLVEF
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHH
VVVWLLNMVLSSRYLPERWRKKAARKHTLLGALALAEEDWLAAEKAMAKGAEKGEIPALN
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LLAAARAAHHQDNHQARDEYLAKAQLEPLAAKAVGTTRTRYLLQQGDLIAAREELDKLNP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
TSKSKLPVLKLAIELYQAQQDWQALKLLLPIVSKKQILADDALQALSLKTNLALLTQAAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANEQELEKCWHWLSRAERKQAEYIALYAIGLSRFERKDEAVKMLLKQVKTSASPSIFKAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AEVLTPADVEAKKQLLALETQFENNVDYQTCLAKLYQQNHDYHQAKIWWQKACYLQDDKN
HHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCH
SLHALADAQEHLGELNRALQSRRNAAKLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]