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The map label for this gene is frdA [C]

Identifier: 157960169

GI number: 157960169

Start: 384142

End: 385644

Strand: Reverse

Name: frdA [C]

Synonym: Spea_0340

Alternate gene names: 157960169

Gene position: 385644-384142 (Counterclockwise)

Preceding gene: 157960172

Following gene: 157960168

Centisome position: 7.45

GC content: 47.77

Gene sequence:

>1503_bases
ATGAAAAGAAGAGACTTTCTAACTAAAAGCATGGGCGTTACCGCAGCAATGGCTTTACCATTTTCAGCGACAGCGGTTTC
ATCTGAAAATAGTTGGGACCGAGAATACGACTTAATCATTGTAGGCAGTGGTTTTGCGGGGTTAGCTGCTGCTTATTCGG
CTAACAAAGCAGGCTTAAAAAACATACTTATCCTTGAAAAGATGGAAACTTGGGGCGGCAACTCAGCGATTTGCGGCGGT
ATTGCTTGTATGCCGAATACCTCTCTACAGAAAAAGCACGGCATTGAAGACTCTGCCGAACTCATGATCAAAGACATGGT
GAAAGCGGGTCGTGGTTTTAATCACCCAGAGCTATGTAAAACTTTAGCTACCGAGGCGCATACCGTATACGACATGCTCA
TTGGTTGTGGCGTCGAATTTATGGATAAGATCATTCGCCTTGGTGGACACAGCGCACCAAGAGCGCATATCCCAGCTAAT
GCCTCTGGCGGCGGAATCGTGGTTCCTATGCACAAGTACCTAGTGAATAAAGGTGTGCAGTTCCAAAACCGAACTCAAGT
CACCAGCTTGCTGCGTGATAAGAATAACGCCATTACCGGCGTTGCCGTACAGGAAAAATTTGATTTTGAAACCGAAGAGT
TCAAAGCCGAGCAAACTTACAAGTCACGTCACGGTGTAGTCGTTGCGACAGGTGGCTGGGGACAAGATAAGAAGTTCGTT
AAAACCACTATGCCTATCTACGCTCACCTAGAAGCGACTGCGCATCCAGGCGCGACAGCAGGCATGATCAAATCGCTACT
TGCTGTTGGCTCGCTACCTATCATGCTCGATATGTATCAGCTTGGCCCTTGGGCTTCTCCTGATGAAAAAGGGGCCGGCC
CAGCTTCCTTCTTTGCCGATTACTCATTCAGTGAAGGTATTGCCATCGACCCAATGACAGGCAAGCGCTTTATGAATGAA
CTTGCCGATCGTCGCACCCGCGCTGAAGCACAGTTGGTCGTATTAGAAAAAGGCAGTGAAGAAAAGCCTAACTACCCATT
CACTTTCTGCAGCGAAGCGACCACTAAACGCGCGGAAGGATTTAAGGGAGCTTACCGCGATGGCGCGGTTAACAAATCTA
ACTCTGTTGCGGAACTCGCCAAACATCACGGCGTCGATGAAGCAGTACTCAGTCAATCTATTGCAGACTGGAACGAGATT
GTTGAGGGCAAGCCTGATCCATTTAATAAGCCACTCGATAGAAGAACCGAATTAAAGCCACCATTTTACTCTCTGAGATT
ATCGCCAAAATTGCATTACTGCATGGGCGGCGTTGCTATCACCCCTAATGCTGAAGTAATTGATGCAACGACTTGTGAGC
CAATCAAAGGTCTATTTGCTGCAGGAGAAGTCGCAGGTGGTACCCACGGTATGGATCGTTTAGGCGGTTGTTCGTCAGTT
GACGGCTTGGTTTTTGGTCAGATTGCAGGCAGAACTGCAGCAAATTATAAGGCGAATGCGTAA

Upstream 100 bases:

>100_bases
TTTATACCTACATATATCAGATAACAATCACAATCTATGCTCGGCACGATTCATATCATCTACCCAGAATGATGACTAAT
ATAAAATTCGTGGAATAATA

Downstream 100 bases:

>100_bases
TGAAAACTTCTTTTGCCGTTGCAGTTATCGCAACGCTATTGTCTTGCAGCGCATTAGCCGCTAAACCGACGATCAAGCAG
CACCATATCGACGCTCTTGG

Product: flavocytochrome c

Products: NA

Alternate protein names: Flavocytochrome c; FL cyt [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MKRRDFLTKSMGVTAAMALPFSATAVSSENSWDREYDLIIVGSGFAGLAAAYSANKAGLKNILILEKMETWGGNSAICGG
IACMPNTSLQKKHGIEDSAELMIKDMVKAGRGFNHPELCKTLATEAHTVYDMLIGCGVEFMDKIIRLGGHSAPRAHIPAN
ASGGGIVVPMHKYLVNKGVQFQNRTQVTSLLRDKNNAITGVAVQEKFDFETEEFKAEQTYKSRHGVVVATGGWGQDKKFV
KTTMPIYAHLEATAHPGATAGMIKSLLAVGSLPIMLDMYQLGPWASPDEKGAGPASFFADYSFSEGIAIDPMTGKRFMNE
LADRRTRAEAQLVVLEKGSEEKPNYPFTFCSEATTKRAEGFKGAYRDGAVNKSNSVAELAKHHGVDEAVLSQSIADWNEI
VEGKPDPFNKPLDRRTELKPPFYSLRLSPKLHYCMGGVAITPNAEVIDATTCEPIKGLFAAGEVAGGTHGMDRLGGCSSV
DGLVFGQIAGRTAANYKANA

Sequences:

>Translated_500_residues
MKRRDFLTKSMGVTAAMALPFSATAVSSENSWDREYDLIIVGSGFAGLAAAYSANKAGLKNILILEKMETWGGNSAICGG
IACMPNTSLQKKHGIEDSAELMIKDMVKAGRGFNHPELCKTLATEAHTVYDMLIGCGVEFMDKIIRLGGHSAPRAHIPAN
ASGGGIVVPMHKYLVNKGVQFQNRTQVTSLLRDKNNAITGVAVQEKFDFETEEFKAEQTYKSRHGVVVATGGWGQDKKFV
KTTMPIYAHLEATAHPGATAGMIKSLLAVGSLPIMLDMYQLGPWASPDEKGAGPASFFADYSFSEGIAIDPMTGKRFMNE
LADRRTRAEAQLVVLEKGSEEKPNYPFTFCSEATTKRAEGFKGAYRDGAVNKSNSVAELAKHHGVDEAVLSQSIADWNEI
VEGKPDPFNKPLDRRTELKPPFYSLRLSPKLHYCMGGVAITPNAEVIDATTCEPIKGLFAAGEVAGGTHGMDRLGGCSSV
DGLVFGQIAGRTAANYKANA
>Mature_500_residues
MKRRDFLTKSMGVTAAMALPFSATAVSSENSWDREYDLIIVGSGFAGLAAAYSANKAGLKNILILEKMETWGGNSAICGG
IACMPNTSLQKKHGIEDSAELMIKDMVKAGRGFNHPELCKTLATEAHTVYDMLIGCGVEFMDKIIRLGGHSAPRAHIPAN
ASGGGIVVPMHKYLVNKGVQFQNRTQVTSLLRDKNNAITGVAVQEKFDFETEEFKAEQTYKSRHGVVVATGGWGQDKKFV
KTTMPIYAHLEATAHPGATAGMIKSLLAVGSLPIMLDMYQLGPWASPDEKGAGPASFFADYSFSEGIAIDPMTGKRFMNE
LADRRTRAEAQLVVLEKGSEEKPNYPFTFCSEATTKRAEGFKGAYRDGAVNKSNSVAELAKHHGVDEAVLSQSIADWNEI
VEGKPDPFNKPLDRRTELKPPFYSLRLSPKLHYCMGGVAITPNAEVIDATTCEPIKGLFAAGEVAGGTHGMDRLGGCSSV
DGLVFGQIAGRTAANYKANA

Specific function: Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to tr

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=466, Percent_Identity=29.6137339055794, Blast_Score=154, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6322511, Length=482, Percent_Identity=27.3858921161826, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6320788, Length=484, Percent_Identity=27.6859504132231, Blast_Score=136, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031
- InterPro:   IPR012286 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 53785; Mature: 53785

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRDFLTKSMGVTAAMALPFSATAVSSENSWDREYDLIIVGSGFAGLAAAYSANKAGLK
CCCHHHHHHHCCCEEEEECCCCCEEECCCCCCCCEEEEEEEECCHHHHHHHHCCCCCCCH
NILILEKMETWGGNSAICGGIACMPNTSLQKKHGIEDSAELMIKDMVKAGRGFNHPELCK
HEEEEEEHHHCCCCCCEECCEEECCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHH
TLATEAHTVYDMLIGCGVEFMDKIIRLGGHSAPRAHIPANASGGGIVVPMHKYLVNKGVQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCC
FQNRTQVTSLLRDKNNAITGVAVQEKFDFETEEFKAEQTYKSRHGVVVATGGWGQDKKFV
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHH
KTTMPIYAHLEATAHPGATAGMIKSLLAVGSLPIMLDMYQLGPWASPDEKGAGPASFFAD
HHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHEEEHHHCCCCCCCCCCCCCCHHHHCC
YSFSEGIAIDPMTGKRFMNELADRRTRAEAQLVVLEKGSEEKPNYPFTFCSEATTKRAEG
CCCCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCHHHHHHHHC
FKGAYRDGAVNKSNSVAELAKHHGVDEAVLSQSIADWNEIVEGKPDPFNKPLDRRTELKP
CCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PFYSLRLSPKLHYCMGGVAITPNAEVIDATTCEPIKGLFAAGEVAGGTHGMDRLGGCSSV
CCEEEEECCCEEEHCCCEEECCCCCEEECCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCC
DGLVFGQIAGRTAANYKANA
CCCEEHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKRRDFLTKSMGVTAAMALPFSATAVSSENSWDREYDLIIVGSGFAGLAAAYSANKAGLK
CCCHHHHHHHCCCEEEEECCCCCEEECCCCCCCCEEEEEEEECCHHHHHHHHCCCCCCCH
NILILEKMETWGGNSAICGGIACMPNTSLQKKHGIEDSAELMIKDMVKAGRGFNHPELCK
HEEEEEEHHHCCCCCCEECCEEECCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHH
TLATEAHTVYDMLIGCGVEFMDKIIRLGGHSAPRAHIPANASGGGIVVPMHKYLVNKGVQ
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCC
FQNRTQVTSLLRDKNNAITGVAVQEKFDFETEEFKAEQTYKSRHGVVVATGGWGQDKKFV
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHH
KTTMPIYAHLEATAHPGATAGMIKSLLAVGSLPIMLDMYQLGPWASPDEKGAGPASFFAD
HHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHEEEHHHCCCCCCCCCCCCCCHHHHCC
YSFSEGIAIDPMTGKRFMNELADRRTRAEAQLVVLEKGSEEKPNYPFTFCSEATTKRAEG
CCCCCCCEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCHHHHHHHHC
FKGAYRDGAVNKSNSVAELAKHHGVDEAVLSQSIADWNEIVEGKPDPFNKPLDRRTELKP
CCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PFYSLRLSPKLHYCMGGVAITPNAEVIDATTCEPIKGLFAAGEVAGGTHGMDRLGGCSSV
CCEEEEECCCEEEHCCCEEECCCCCEEECCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCC
DGLVFGQIAGRTAANYKANA
CCCEEHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11425747; 12368813; 10581551 [H]