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The map label for this gene is gmhA [H]

Identifier: 157960079

GI number: 157960079

Start: 279330

End: 279923

Strand: Reverse

Name: gmhA [H]

Synonym: Spea_0250

Alternate gene names: 157960079

Gene position: 279923-279330 (Counterclockwise)

Preceding gene: 157960080

Following gene: 157960078

Centisome position: 5.41

GC content: 48.32

Gene sequence:

>594_bases
ATGTTAGAACGCATAAAAGACAGCTTTACCGAATCAATTCAAACTAAGATTGATGCATCTGAAGCCCTGCCAGAGTCAAT
CGCAAAAGCCGCAGAGATGATGGTTAACTGTCTACTCGGTGGTAATAAAATTTTGGCCTGTGGTAATGGCGGTAGTGCTG
GCGATGCGCAGCACTTCTCTGCTGAACTGTTGAACCGCTATGAAATTGAGCGTCCACCGCTACCTGCGATTGCATTAAGC
TGTGATACTTCAACCATCACTGCGATTGCTAACGATTACAGCTATGATGAGATTTTCTCTAAGCAGATCATGGCACTGGG
TCAGCCTGGCGATATCCTGCTAGCCATTTCAACTAGTGGTAATTCAGGTAACGTAATTAAGGCGATGGAAGCAGCCCTAA
GCCGTGATATGACGATTGTCTCGTTAACCGGTAAAGACGGCGGCGCGATGGCTGGCCTTCTGAGCGTCAATGACGTTGAG
ATCCGCGTACCTTCAAACGTGACGGCACGTATTCAGGAAGTTCACCTGCTAGCGATTCACTGCCTATGTGACAATATCGA
CCGCACACTATTCCCGCAGGACGAGCAGGCATGA

Upstream 100 bases:

>100_bases
ATGCAGTGGATCCGCGATGCTTTTTAAATAGCTTAATTTTCATATGCTCAGTTCGGTAAAATACCGTTATACCAAGCATA
TATAAACATAGGGTTTATCC

Downstream 100 bases:

>100_bases
GAGCACTGCTCCCATTAATCGCCGTTGTATTAATGCTGCAAGGCTGCGCAGGAGCCATTATGGTCGGCGCAGTTGGCGGT
GCAATGATGGTTAATGACGA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MLERIKDSFTESIQTKIDASEALPESIAKAAEMMVNCLLGGNKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALS
CDTSTITAIANDYSYDEIFSKQIMALGQPGDILLAISTSGNSGNVIKAMEAALSRDMTIVSLTGKDGGAMAGLLSVNDVE
IRVPSNVTARIQEVHLLAIHCLCDNIDRTLFPQDEQA

Sequences:

>Translated_197_residues
MLERIKDSFTESIQTKIDASEALPESIAKAAEMMVNCLLGGNKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALS
CDTSTITAIANDYSYDEIFSKQIMALGQPGDILLAISTSGNSGNVIKAMEAALSRDMTIVSLTGKDGGAMAGLLSVNDVE
IRVPSNVTARIQEVHLLAIHCLCDNIDRTLFPQDEQA
>Mature_197_residues
MLERIKDSFTESIQTKIDASEALPESIAKAAEMMVNCLLGGNKILACGNGGSAGDAQHFSAELLNRYEIERPPLPAIALS
CDTSTITAIANDYSYDEIFSKQIMALGQPGDILLAISTSGNSGNVIKAMEAALSRDMTIVSLTGKDGGAMAGLLSVNDVE
IRVPSNVTARIQEVHLLAIHCLCDNIDRTLFPQDEQA

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=195, Percent_Identity=62.5641025641026, Blast_Score=260, Evalue=5e-71,
Organism=Escherichia coli, GI1786416, Length=189, Percent_Identity=45.5026455026455, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20956; Mature: 20956

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERIKDSFTESIQTKIDASEALPESIAKAAEMMVNCLLGGNKILACGNGGSAGDAQHFS
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
AELLNRYEIERPPLPAIALSCDTSTITAIANDYSYDEIFSKQIMALGQPGDILLAISTSG
HHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCC
NSGNVIKAMEAALSRDMTIVSLTGKDGGAMAGLLSVNDVEIRVPSNVTARIQEVHLLAIH
CCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECEEEEEECCCCHHHHHHHHHHHHH
CLCDNIDRTLFPQDEQA
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLERIKDSFTESIQTKIDASEALPESIAKAAEMMVNCLLGGNKILACGNGGSAGDAQHFS
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
AELLNRYEIERPPLPAIALSCDTSTITAIANDYSYDEIFSKQIMALGQPGDILLAISTSG
HHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCC
NSGNVIKAMEAALSRDMTIVSLTGKDGGAMAGLLSVNDVEIRVPSNVTARIQEVHLLAIH
CCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECEEEEEECCCCHHHHHHHHHHHHH
CLCDNIDRTLFPQDEQA
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA