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The map label for this gene is cysQ [H]

Identifier: 157959987

GI number: 157959987

Start: 171797

End: 172606

Strand: Direct

Name: cysQ [H]

Synonym: Spea_0157

Alternate gene names: 157959987

Gene position: 171797-172606 (Clockwise)

Preceding gene: 157959986

Following gene: 157959988

Centisome position: 3.32

GC content: 45.43

Gene sequence:

>810_bases
ATGAAGCCAGAGAATTATGTAGATCAAGTCATTGAAATTGCTACGCTCGCGGGTAGCAAAATCCGTGAAATTTATCAGAA
AGGCGATTTTGAGCGAGAGATAAAATCTGATAATACGCCAGTGACTTCTGCCGATCTCGCTGCTCATGAAATCATAACTA
AGGCTTTGATGGCGCTAACGCCAGATATCCCGGTCTTATCTGAAGAAGATGCCGATATCCCATTTGCTGAACGTTGTGAT
TGGCAACGTTATTGGTTGGTGGATCCGCTAGACGGAACCGGTGAGTTTATTGCTGGTAGTGGTGATTTTTCGGTGATCAT
TGCCCTCGTTGAGCATAACCGGCCGATTTTAGGCGTGGTGTATGTGCCAATGACAGAGGTCTGCTATTACGGTATTGCAG
GTCTAGGTTCTTATAAGCGTAAAGATGGTACAGAAGTGCGGATCAGCAGCAAGCAACTGACTAAAGACTCGAATGGGTTA
CGTTTAGCTGTGAGTCGCCGTCAAGATCCTAAGTCAGTGATTAAGTTATTTAATCAAGAAAAGCACTGTGAGTTAGTAGT
GCTTGGTGGAGCGGCATTAAAGAGCTGTTTGGTAGCAGAAGGTCGCGCCGACTGCTACGTGCGTATTGGCCCGACGGGTG
AGTGGGATACAGGTGCTGCGCAGATTATCGTTGAGGAGGCGGGTGGTCAGATAATGGATCTTAACCTGCAGCCATTGACT
TATAACGAGCGAGAAAGCTTAGAAAATCCTAATTTTATTGTCGTGGGGTCTCCTGCATTAGAATGGGATAAAATCTTAAT
CAATGAATGA

Upstream 100 bases:

>100_bases
AGTCTCGCAGTGTAAGCGCTTTATTTTTAGCTCAGAAACATCTACAACTTAGATAGTTTAAATTGGCACTCGTTATTGGT
ATTAGGCTGTTGGAGTCATT

Downstream 100 bases:

>100_bases
TCCGATTGAGCTTTGCCTCGCGAGTAAACCTGAACTCACCGCGATTGATGCCCTCGAACAACAATGTTTTGCTGGGCATT
GCTATCCCGACTTTTTCTTT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MKPENYVDQVIEIATLAGSKIREIYQKGDFEREIKSDNTPVTSADLAAHEIITKALMALTPDIPVLSEEDADIPFAERCD
WQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVVYVPMTEVCYYGIAGLGSYKRKDGTEVRISSKQLTKDSNGL
RLAVSRRQDPKSVIKLFNQEKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPLT
YNERESLENPNFIVVGSPALEWDKILINE

Sequences:

>Translated_269_residues
MKPENYVDQVIEIATLAGSKIREIYQKGDFEREIKSDNTPVTSADLAAHEIITKALMALTPDIPVLSEEDADIPFAERCD
WQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVVYVPMTEVCYYGIAGLGSYKRKDGTEVRISSKQLTKDSNGL
RLAVSRRQDPKSVIKLFNQEKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPLT
YNERESLENPNFIVVGSPALEWDKILINE
>Mature_269_residues
MKPENYVDQVIEIATLAGSKIREIYQKGDFEREIKSDNTPVTSADLAAHEIITKALMALTPDIPVLSEEDADIPFAERCD
WQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVVYVPMTEVCYYGIAGLGSYKRKDGTEVRISSKQLTKDSNGL
RLAVSRRQDPKSVIKLFNQEKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPLT
YNERESLENPNFIVVGSPALEWDKILINE

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI221625487, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI5031789, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1790659, Length=251, Percent_Identity=43.4262948207171, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1788882, Length=233, Percent_Identity=31.7596566523605, Blast_Score=84, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193202572, Length=253, Percent_Identity=28.0632411067194, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193202570, Length=257, Percent_Identity=26.8482490272374, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995897, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=239, Percent_Identity=27.6150627615063, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24664922, Length=278, Percent_Identity=26.2589928057554, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24664926, Length=238, Percent_Identity=26.4705882352941, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24664918, Length=267, Percent_Identity=26.2172284644195, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357329, Length=237, Percent_Identity=26.1603375527426, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29729; Mature: 29729

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPENYVDQVIEIATLAGSKIREIYQKGDFEREIKSDNTPVTSADLAAHEIITKALMALT
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PDIPVLSEEDADIPFAERCDWQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVV
CCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCEEEEE
YVPMTEVCYYGIAGLGSYKRKDGTEVRISSKQLTKDSNGLRLAVSRRQDPKSVIKLFNQE
ECCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHCCC
KHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPLT
CCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCC
YNERESLENPNFIVVGSPALEWDKILINE
CCHHHCCCCCCEEEECCCCCCCCEEEECC
>Mature Secondary Structure
MKPENYVDQVIEIATLAGSKIREIYQKGDFEREIKSDNTPVTSADLAAHEIITKALMALT
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PDIPVLSEEDADIPFAERCDWQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVV
CCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCEEEEE
YVPMTEVCYYGIAGLGSYKRKDGTEVRISSKQLTKDSNGLRLAVSRRQDPKSVIKLFNQE
ECCHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHCCC
KHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPLT
CCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCC
YNERESLENPNFIVVGSPALEWDKILINE
CCHHHCCCCCCEEEECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]