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The map label for this gene is ribB [H]

Identifier: 157959961

GI number: 157959961

Start: 145678

End: 146316

Strand: Reverse

Name: ribB [H]

Synonym: Spea_0131

Alternate gene names: 157959961

Gene position: 146316-145678 (Counterclockwise)

Preceding gene: 157959964

Following gene: 157959960

Centisome position: 2.83

GC content: 50.08

Gene sequence:

>639_bases
ATGAATCAGTCTTTACTTGCCCCTTATGGCAATCCAATCGAACGTGTTAATGCAGCGCTTAGCGCACTTCGCCAAGGCAA
AGGTGTGTTAGTGGTCGATGATGAAGATCGTGAAAATGAAGGCGATCTGATCTATTCAGCCGAAACGCTTACCAACCAAC
AGATGGCACTACTCATTCGCGAATGCAGTGGTATTGTTTGTCTATGTCTAACCGATGAACGTATCAAGCAGTTACAACTT
CCACCTATGGTGAGTGACAACAATAGCCAATATGGCACCGCCTTTACCGTTAGCATCGAAGCCAAACAAGGTGTCACCAC
TGGTGTTTCGGCAGCCGATCGCGTGACGACCATCAAGGCAGCTATCGCCGATGATGCTAAGCCCGATGATTTAGCCCGCC
CAGGCCATGTGTACCCGCTGCGTGCTCGTCCAGGTGGCGTATTAGAGCGTCGTGGCCATACAGAAGGCACGGTTGATCTG
ATGAAACTCGCCGGATTACAGCCTTTTGGCGTGCTTTGTGAAGTCACTCTACCCGACGGCACCATGGCCCGCTTGCCTGA
AATTGTCGAATTTGCTCAGCAGCATGATATGCCGGTACTGACCATCGAAGACATTGTTGCTTACCGTAATACTCAGTAA

Upstream 100 bases:

>100_bases
GCACATCAGCTTGTGTCGATCCGTTCGACTCTGACGATGTGTCATTTTCTGTACGCCCTGATTCTGGTCAACCCAATGTT
GTATTTTAAGGATGTTATCC

Downstream 100 bases:

>100_bases
TTAAGATCGGAATCAACAGCCGCTGCCTATGCGGCTGTTTTATATCCTATTTAAGCTTTACTATCACTTAGTTATATTCA
TTAAATATAAAAAACGGGTT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNQSLLAPYGNPIERVNAALSALRQGKGVLVVDDEDRENEGDLIYSAETLTNQQMALLIRECSGIVCLCLTDERIKQLQL
PPMVSDNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIKAAIADDAKPDDLARPGHVYPLRARPGGVLERRGHTEGTVDL
MKLAGLQPFGVLCEVTLPDGTMARLPEIVEFAQQHDMPVLTIEDIVAYRNTQ

Sequences:

>Translated_212_residues
MNQSLLAPYGNPIERVNAALSALRQGKGVLVVDDEDRENEGDLIYSAETLTNQQMALLIRECSGIVCLCLTDERIKQLQL
PPMVSDNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIKAAIADDAKPDDLARPGHVYPLRARPGGVLERRGHTEGTVDL
MKLAGLQPFGVLCEVTLPDGTMARLPEIVEFAQQHDMPVLTIEDIVAYRNTQ
>Mature_212_residues
MNQSLLAPYGNPIERVNAALSALRQGKGVLVVDDEDRENEGDLIYSAETLTNQQMALLIRECSGIVCLCLTDERIKQLQL
PPMVSDNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIKAAIADDAKPDDLARPGHVYPLRARPGGVLERRGHTEGTVDL
MKLAGLQPFGVLCEVTLPDGTMARLPEIVEFAQQHDMPVLTIEDIVAYRNTQ

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=212, Percent_Identity=67.4528301886792, Blast_Score=307, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=42.7860696517413, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23016; Mature: 23016

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSLLAPYGNPIERVNAALSALRQGKGVLVVDDEDRENEGDLIYSAETLTNQQMALLIR
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEHHHHCCHHHHHHHH
ECSGIVCLCLTDERIKQLQLPPMVSDNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIKA
HCCCEEEEEECHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHH
AIADDAKPDDLARPGHVYPLRARPGGVLERRGHTEGTVDLMKLAGLQPFGVLCEVTLPDG
HHCCCCCCCCCCCCCCEEEECCCCCCCHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCC
TMARLPEIVEFAQQHDMPVLTIEDIVAYRNTQ
HHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCC
>Mature Secondary Structure
MNQSLLAPYGNPIERVNAALSALRQGKGVLVVDDEDRENEGDLIYSAETLTNQQMALLIR
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEHHHHCCHHHHHHHH
ECSGIVCLCLTDERIKQLQLPPMVSDNNSQYGTAFTVSIEAKQGVTTGVSAADRVTTIKA
HCCCEEEEEECHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHH
AIADDAKPDDLARPGHVYPLRARPGGVLERRGHTEGTVDLMKLAGLQPFGVLCEVTLPDG
HHCCCCCCCCCCCCCCEEEECCCCCCCHHCCCCCCCHHHHHHHCCCCCCCEEEEEECCCC
TMARLPEIVEFAQQHDMPVLTIEDIVAYRNTQ
HHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA