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The map label for this gene is kdkA [H]

Identifier: 157959940

GI number: 157959940

Start: 123700

End: 124431

Strand: Reverse

Name: kdkA [H]

Synonym: Spea_0110

Alternate gene names: 157959940

Gene position: 124431-123700 (Counterclockwise)

Preceding gene: 157959945

Following gene: 157959938

Centisome position: 2.4

GC content: 47.4

Gene sequence:

>732_bases
ATGAAGTTTAAAAAAACTGCCAAAGGCAGTATCGCTTATTGCCAATACACACCATCAAGTATCGAACCTAACTGGTTTGC
TGCCGACTTTTGGCGTCAGCAATCTGCCATTACTGGTTCGTCGAAGGGGCGTTACACCACCTGGTTCGTCGATGCTAACA
GCGTTGGCAAAGCTCAAAACCAGTGGGTACTTCGTCACTACTATCGTGGTGGTTTGATAGAAAAAATTAGCCGTGACCAA
TATCTGTTTACCGGTTTAGAAAAAACCCGTGCGGTAGCTGAACTAGCGCTGCTAGAAAACCTTTACCAGCAAGGCTTTGC
CGTACCTAAGCCGATCGCCGCCAATGTTGAGCGCTCAGGTCTGTTCTATCGTGCCGACTTAATTATAGAGCGGGTAGAAG
GTGCCGAAGACTTAGTCGCCAGATTAAGCAAAGCCGCTATGACGGATGCGCAGTGGCTGGTTCTCGGTGAAACCATTGCC
GAATTTCACAATCACGGCGTTTACCACGCGGACCTCAACGCTAAGAATATCCTTATCTGTGATGACAAGTTTTATCTGAT
TGATTTTGACCGTGGTGAGCTAAGAAAGCCCAACAGTCAATGGCAGCAAGCCAACATGAGTCGTTTGTTGCGCTCCTTTA
GAAAGGAGCTGGGTAAATTGCCAACGCTGGCGTTTAATGATGGCAATTGGCAGCAACTGCATCAAGGCTATCTAGCCAAG
CTCAATCATTAG

Upstream 100 bases:

>100_bases
AGTTGATAGGCTCATTAGTGCTCGAAGGTTATTTAACGCAATCTACCGATCTTAATGTAGAATGCCTGCAGGTTCCACGC
TTTAGCTTACAATTCTATCT

Downstream 100 bases:

>100_bases
TGTTAGCAATCAAATTCAATAAAAAAGGTCAGCGCAAAGCTGACCTTTTTTGCTGATATCACCACACTAACGCTGAATAT
AACTTTCCACTACTGCCAGC

Product: 3-deoxy-D-manno-octulosonic-acid kinase

Products: NA

Alternate protein names: KDO kinase; SPS1 protein [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKFKKTAKGSIAYCQYTPSSIEPNWFAADFWRQQSAITGSSKGRYTTWFVDANSVGKAQNQWVLRHYYRGGLIEKISRDQ
YLFTGLEKTRAVAELALLENLYQQGFAVPKPIAANVERSGLFYRADLIIERVEGAEDLVARLSKAAMTDAQWLVLGETIA
EFHNHGVYHADLNAKNILICDDKFYLIDFDRGELRKPNSQWQQANMSRLLRSFRKELGKLPTLAFNDGNWQQLHQGYLAK
LNH

Sequences:

>Translated_243_residues
MKFKKTAKGSIAYCQYTPSSIEPNWFAADFWRQQSAITGSSKGRYTTWFVDANSVGKAQNQWVLRHYYRGGLIEKISRDQ
YLFTGLEKTRAVAELALLENLYQQGFAVPKPIAANVERSGLFYRADLIIERVEGAEDLVARLSKAAMTDAQWLVLGETIA
EFHNHGVYHADLNAKNILICDDKFYLIDFDRGELRKPNSQWQQANMSRLLRSFRKELGKLPTLAFNDGNWQQLHQGYLAK
LNH
>Mature_243_residues
MKFKKTAKGSIAYCQYTPSSIEPNWFAADFWRQQSAITGSSKGRYTTWFVDANSVGKAQNQWVLRHYYRGGLIEKISRDQ
YLFTGLEKTRAVAELALLENLYQQGFAVPKPIAANVERSGLFYRADLIIERVEGAEDLVARLSKAAMTDAQWLVLGETIA
EFHNHGVYHADLNAKNILICDDKFYLIDFDRGELRKPNSQWQQANMSRLLRSFRKELGKLPTLAFNDGNWQQLHQGYLAK
LNH

Specific function: ATP-dependent phosphorylation of 3-deoxy-D-manno- octulosonic acid at the 4-OH position [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022826
- InterPro:   IPR011009
- InterPro:   IPR010440 [H]

Pfam domain/function: PF06293 Kdo [H]

EC number: NA

Molecular weight: Translated: 27871; Mature: 27871

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKKTAKGSIAYCQYTPSSIEPNWFAADFWRQQSAITGSSKGRYTTWFVDANSVGKAQN
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHH
QWVLRHYYRGGLIEKISRDQYLFTGLEKTRAVAELALLENLYQQGFAVPKPIAANVERSG
HHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHCC
LFYRADLIIERVEGAEDLVARLSKAAMTDAQWLVLGETIAEFHNHGVYHADLNAKNILIC
CEEHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEECCCCEEEEE
DDKFYLIDFDRGELRKPNSQWQQANMSRLLRSFRKELGKLPTLAFNDGNWQQLHQGYLAK
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
LNH
CCC
>Mature Secondary Structure
MKFKKTAKGSIAYCQYTPSSIEPNWFAADFWRQQSAITGSSKGRYTTWFVDANSVGKAQN
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHH
QWVLRHYYRGGLIEKISRDQYLFTGLEKTRAVAELALLENLYQQGFAVPKPIAANVERSG
HHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHCC
LFYRADLIIERVEGAEDLVARLSKAAMTDAQWLVLGETIAEFHNHGVYHADLNAKNILIC
CEEHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCEEEECCCCEEEEE
DDKFYLIDFDRGELRKPNSQWQQANMSRLLRSFRKELGKLPTLAFNDGNWQQLHQGYLAK
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
LNH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA