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The map label for this gene is fabH [H]

Identifier: 157826224

GI number: 157826224

Start: 1066419

End: 1067372

Strand: Reverse

Name: fabH [H]

Synonym: A1C_06015

Alternate gene names: 157826224

Gene position: 1067372-1066419 (Counterclockwise)

Preceding gene: 157826225

Following gene: 157826223

Centisome position: 86.7

GC content: 36.16

Gene sequence:

>954_bases
ATGACCTGTAAAATTATTGGTTGCGGCGGGTATCTTCCTTCAAAAATAGTTAGTAATGATGAGCTTGCAAAATTTGTAGA
GACTAATGATGAATGGATTAGAACAAGAAGCGGCATCTCACAACGTCATATAGCAGACGATAATGAATATACTTCCCATC
TTGCTTTAAAATCAGCTGAACAAGCTATAGCAGATGCGAGGGTGTCGGCAAATGATGTTGATTTAATTATTACATGTACT
ACTACTTCCGATAATAGTTTTCCTTCTGTTGCTACTAAACTACATGGCTATCTTGGTTTAACTAATATACCATCTTTTGA
TTTACAAGCAGTATGTGCCGGTTTTGTTTATGGTTTACAAGTGGCGGATTCTCTTATTGCGTCCGGTAAATATAAAACTA
TTTTGCTTATAGGAGCCGAGAAAATGACCTCGCTCTTAGATTGGAATGACAGGTCTACTTGTGTTTTATTCGGTGATGGA
GCAGGTAGCGTAATATTACAGCGTAGTAGTGATGATTCCGGATTAATAGATAGTAATATCTTTTCAAGCGGGGCTGATTA
TGAAATATTATACACAAGCGGTGGTATAAGCATGAACGGTACTAGCGGGAAAATAATAATGCAGGGCCAAAAATTATTTC
GTCATGCAATAGAAAAAATGCAACAATCTATAGAAGATTTGCTGCATACTAATCAATTCAGTGTGAGCGGTATTGATTAT
TTTATACCTCATCAAGCAAATATCCGTATTATAAATAAACTCGCTGAACTATTAAATATAGAAGAGCATAAAGTAGTGAA
AACCGTAGAAAAACACGCTAACTGCTCTGCTGCTTCTATTCCGCTTGCTTTGAGTACTCTAAAAGCATCAGGCAAAATAA
AAAAAGGTGATATTCTACTATTTTCAGCTATCGGTGCAGGTTTAACTTGGGGTAGTGCATTAATTAGATGGTGA

Upstream 100 bases:

>100_bases
AAACTTCCGCATCACGTTTCTTTAGTCGATGGTACTTATAATAATCGTCAAGTAGTAACAAAGAGAATTGAAACGGAAGA
AGCAGTAGCCTAAAGATTTT

Downstream 100 bases:

>100_bases
GTATACTCGTTTTATTTCAAAAATTGTCGTCGTTGTCTAATATTGCTTGATCCTCACATATTATATATATGTTGCCGGTT
ATAAGCTTCAAAATCGATTC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTCKIIGCGGYLPSKIVSNDELAKFVETNDEWIRTRSGISQRHIADDNEYTSHLALKSAEQAIADARVSANDVDLIITCT
TTSDNSFPSVATKLHGYLGLTNIPSFDLQAVCAGFVYGLQVADSLIASGKYKTILLIGAEKMTSLLDWNDRSTCVLFGDG
AGSVILQRSSDDSGLIDSNIFSSGADYEILYTSGGISMNGTSGKIIMQGQKLFRHAIEKMQQSIEDLLHTNQFSVSGIDY
FIPHQANIRIINKLAELLNIEEHKVVKTVEKHANCSAASIPLALSTLKASGKIKKGDILLFSAIGAGLTWGSALIRW

Sequences:

>Translated_317_residues
MTCKIIGCGGYLPSKIVSNDELAKFVETNDEWIRTRSGISQRHIADDNEYTSHLALKSAEQAIADARVSANDVDLIITCT
TTSDNSFPSVATKLHGYLGLTNIPSFDLQAVCAGFVYGLQVADSLIASGKYKTILLIGAEKMTSLLDWNDRSTCVLFGDG
AGSVILQRSSDDSGLIDSNIFSSGADYEILYTSGGISMNGTSGKIIMQGQKLFRHAIEKMQQSIEDLLHTNQFSVSGIDY
FIPHQANIRIINKLAELLNIEEHKVVKTVEKHANCSAASIPLALSTLKASGKIKKGDILLFSAIGAGLTWGSALIRW
>Mature_316_residues
TCKIIGCGGYLPSKIVSNDELAKFVETNDEWIRTRSGISQRHIADDNEYTSHLALKSAEQAIADARVSANDVDLIITCTT
TSDNSFPSVATKLHGYLGLTNIPSFDLQAVCAGFVYGLQVADSLIASGKYKTILLIGAEKMTSLLDWNDRSTCVLFGDGA
GSVILQRSSDDSGLIDSNIFSSGADYEILYTSGGISMNGTSGKIIMQGQKLFRHAIEKMQQSIEDLLHTNQFSVSGIDYF
IPHQANIRIINKLAELLNIEEHKVVKTVEKHANCSAASIPLALSTLKASGKIKKGDILLFSAIGAGLTWGSALIRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=318, Percent_Identity=39.3081761006289, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34253; Mature: 34122

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCKIIGCGGYLPSKIVSNDELAKFVETNDEWIRTRSGISQRHIADDNEYTSHLALKSAE
CEEEEEEECCCCCHHHCCCHHHHHHHHCCHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHH
QAIADARVSANDVDLIITCTTTSDNSFPSVATKLHGYLGLTNIPSFDLQAVCAGFVYGLQ
HHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VADSLIASGKYKTILLIGAEKMTSLLDWNDRSTCVLFGDGAGSVILQRSSDDSGLIDSNI
HHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCHH
FSSGADYEILYTSGGISMNGTSGKIIMQGQKLFRHAIEKMQQSIEDLLHTNQFSVSGIDY
HCCCCCEEEEEECCCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEECCEEE
FIPHQANIRIINKLAELLNIEEHKVVKTVEKHANCSAASIPLALSTLKASGKIKKGDILL
ECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHEEEHHCCCCEECCCEEE
FSAIGAGLTWGSALIRW
EEECCCCCHHHHHHHCC
>Mature Secondary Structure 
TCKIIGCGGYLPSKIVSNDELAKFVETNDEWIRTRSGISQRHIADDNEYTSHLALKSAE
EEEEEEECCCCCHHHCCCHHHHHHHHCCHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHH
QAIADARVSANDVDLIITCTTTSDNSFPSVATKLHGYLGLTNIPSFDLQAVCAGFVYGLQ
HHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VADSLIASGKYKTILLIGAEKMTSLLDWNDRSTCVLFGDGAGSVILQRSSDDSGLIDSNI
HHHHHHHCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCHH
FSSGADYEILYTSGGISMNGTSGKIIMQGQKLFRHAIEKMQQSIEDLLHTNQFSVSGIDY
HCCCCCEEEEEECCCEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEECCEEE
FIPHQANIRIINKLAELLNIEEHKVVKTVEKHANCSAASIPLALSTLKASGKIKKGDILL
ECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHEEEHHCCCCEECCCEEE
FSAIGAGLTWGSALIRW
EEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]