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The map label for this gene is addA [H]

Identifier: 157826193

GI number: 157826193

Start: 1039676

End: 1042132

Strand: Reverse

Name: addA [H]

Synonym: A1C_05850

Alternate gene names: 157826193

Gene position: 1042132-1039676 (Counterclockwise)

Preceding gene: 157826194

Following gene: 157826192

Centisome position: 84.65

GC content: 31.3

Gene sequence:

>2457_bases
ATGAGCAATCTACAACAACAAGCCTCCGATCCTAATTATTCTGTGTGGGTATCGGCATCTGCCGGTACAGGTAAAACCAA
AATCCTGACCGATCGATTTTTACGTTTGTTAATAACAGGCGTAGAACCTACCAATATTTTATGTCTTACTTTTACTAATT
CTGCAGCTATAGAGATGAAAGCAAGAATTAATAGTAAGCTTAAACATCTTTCTCTTTGTGATGCAGAAAATTTAGAAAAT
GAACTCTTCTTAATGAGTGGTAATAAGCCGCTACCTCAAGAAATAGAAAATGCAAAAACTTTATACGATAAAATACTAAA
GAGCAACGAGCCTTTAAATATCTATACAATTCATGCATTTTGTCAAAAAATCCTTAACACTTTTCCTTTAGAAGCAGGTA
TCACACCGGAATTTAAAATTCTTGAAGAAACTAAATTACAAGATATCTTCCTAAATATCAGAAATGAAATCTACTTAAGT
GATGAGCATAATGACTTCATTAAAATTTTACTTAACCGCTTTCATGAAATAACCCTGCAAGATATTTTTAATGAAATAAT
CGATCAGAAAATTAAATTCAAGAAGTTATTTACTCATAAAACTATTCCAAATGAAATATATAATAAAAGATTAGCGTTTG
TGGAATTAAATAATATTTACGATAAGGTAAAAAGCTTATTTGCAGAATATGATTTGGAAATAGAGCCGAAAGAAATCTTT
TTTACAAAAGACGGAAAAAAACGTAAAAGCCTTTTATCGAAAGAATTAAGAAGAAAATATCCTAAATTATTGCTAGAGCT
AGAAAAAATTATCTCTGAAATTTACCGTTTAGATGAGTTGCATCGCATAGAGAAGCTAGAATATCATACGAACTTACTTA
CTAAACTTGCTCATATTATTTTAAAAAAATACGATTCATATAAAGAAGAAAATAATTTACTCGATTACGATGATCTAATT
TACTACACCGAAAAATTGCTGAATAATAACACTACGCATGAGTGGTTGTTGCACAAGCTTGAAAACGAGATAAAACACAT
TCTTGTTGACGAAGCACAGGACACAAGCCCCCCGCAGTGGAATATTATCACTACTTTAATAACAGCGTTTAATGCGGCAG
ATAAACCAAGTAATAGTACCTTTATAGTTGGTGACGATAAACAGTCCATCTTCAGTTTTCAAGGGTCTGATCTTCATAAT
TTCAGCTTAGTAAAGGAGCAACTAAAAGCAAACCTTACAAGTGCTAATAAAAAATTCAAAAATATCACCCTTGAATTTTC
TTATAGATCATGTGCAGAGATTTTACAATTTACTCATAATGTTTTGAAAAATATAAAATCCAATTACCCTAGTTTATTCC
TTGCGGATAATCCTTTAATATCCTCATGTCGTACACATCAAGGCCTAGTGACAATTTGGCCTTTAGTAATGAGTGAAAAA
CAAGAAGAGCTTTTTTGGGCATTGCCTGAAGATTATGAACATTCTAAATCTGCTGCTGATTTACTTATAGAAAAAATTGT
AAATTTCATACAAGAACAAATAGAAAGCAAAGAAATTTTACCGTCTACCGTAAGCACAATATCTGAAAAAGATTTCATAA
TATTAGTAAGAAAGAGAGATGAATTTAGCAATAATCTTATAAAAGAACTTAGTAACGCTAAGCTTAACGTTGAGATAAGC
GATAGAATTAATATTAAAGAAAATCTAACTATAATGGATTTAATGTCCGTGGCTAAATTTGTATTACTACCAGATGATGA
TCTAAACCTTGCCGGTTTACTAAAATCACCGATTATCGGCATTAACGAAAAGCAATTATACGTACTTCTTATAAATAAAA
ACGATAATAGTTTATGGGATAATCTATCTGCTTGTGAAGCAATATACGCTAAGTTAAATGCCCTAATTGAAATTTATAAA
ATATCGACTGTTGAGAATTTCTTTGATTTAGTGGTGCATAATCTAAATTTACGAGAGCTTTACGATGATGATAGTGATGA
TATGATAAATGAGCTATTAACGTTAAGCAAACACTATGCAAATGATATAGATAATTCACTGCAAGGCTTCGTTGCTTGGT
TTGAGAATAACGATATCTACATCAAACGTGATATGGAGCATTCAGATAAAATAAGAGTAATGACCGTACACGGCTCTAAA
GGACTTGAAGCTCCTATTGTTATATTATGCGATTCTACTACTTTGCCTGTAAGTAGCAATCAATTTATTTGGGACGATAA
AGGGGAAATGTTCTTCTCTGCTAATATTGTAGATACGCCGGAGTTCCTACAAGAATTAAAAGAAGCTGCAAAATTACAAG
ATTTGCAAGAATATATAAGACTACTCTATGTTGCAATGACAAGAGCTAAAGACCGGCTAATTATATGCGGTTTTAGTAAT
AAATCTAACACTCCTGAAAATTGCTGGTATGAAATAGTCAAGCAAACTTTTGATTAA

Upstream 100 bases:

>100_bases
CGTGGATGTCATCCCACGACTTGATCGCTGGATCCAGAAAAATAATTAAAAAGACTGGACCACGTGGTCAAGCCACGTGG
TGACAGTAAGCGATACATAA

Downstream 100 bases:

>100_bases
CAGCTGCTTTATTAAGTCATTATTCGGCTTTCCAACTCTCCTAAACGTTACTCAATTCTCTCTATATCTTCTTTTGTGAA
AGGATTTCTTAATAAAAATG

Product: ATP-dependent helicase

Products: NA

Alternate protein names: ATP-dependent helicase/nuclease AddA [H]

Number of amino acids: Translated: 818; Mature: 817

Protein sequence:

>818_residues
MSNLQQQASDPNYSVWVSASAGTGKTKILTDRFLRLLITGVEPTNILCLTFTNSAAIEMKARINSKLKHLSLCDAENLEN
ELFLMSGNKPLPQEIENAKTLYDKILKSNEPLNIYTIHAFCQKILNTFPLEAGITPEFKILEETKLQDIFLNIRNEIYLS
DEHNDFIKILLNRFHEITLQDIFNEIIDQKIKFKKLFTHKTIPNEIYNKRLAFVELNNIYDKVKSLFAEYDLEIEPKEIF
FTKDGKKRKSLLSKELRRKYPKLLLELEKIISEIYRLDELHRIEKLEYHTNLLTKLAHIILKKYDSYKEENNLLDYDDLI
YYTEKLLNNNTTHEWLLHKLENEIKHILVDEAQDTSPPQWNIITTLITAFNAADKPSNSTFIVGDDKQSIFSFQGSDLHN
FSLVKEQLKANLTSANKKFKNITLEFSYRSCAEILQFTHNVLKNIKSNYPSLFLADNPLISSCRTHQGLVTIWPLVMSEK
QEELFWALPEDYEHSKSAADLLIEKIVNFIQEQIESKEILPSTVSTISEKDFIILVRKRDEFSNNLIKELSNAKLNVEIS
DRINIKENLTIMDLMSVAKFVLLPDDDLNLAGLLKSPIIGINEKQLYVLLINKNDNSLWDNLSACEAIYAKLNALIEIYK
ISTVENFFDLVVHNLNLRELYDDDSDDMINELLTLSKHYANDIDNSLQGFVAWFENNDIYIKRDMEHSDKIRVMTVHGSK
GLEAPIVILCDSTTLPVSSNQFIWDDKGEMFFSANIVDTPEFLQELKEAAKLQDLQEYIRLLYVAMTRAKDRLIICGFSN
KSNTPENCWYEIVKQTFD

Sequences:

>Translated_818_residues
MSNLQQQASDPNYSVWVSASAGTGKTKILTDRFLRLLITGVEPTNILCLTFTNSAAIEMKARINSKLKHLSLCDAENLEN
ELFLMSGNKPLPQEIENAKTLYDKILKSNEPLNIYTIHAFCQKILNTFPLEAGITPEFKILEETKLQDIFLNIRNEIYLS
DEHNDFIKILLNRFHEITLQDIFNEIIDQKIKFKKLFTHKTIPNEIYNKRLAFVELNNIYDKVKSLFAEYDLEIEPKEIF
FTKDGKKRKSLLSKELRRKYPKLLLELEKIISEIYRLDELHRIEKLEYHTNLLTKLAHIILKKYDSYKEENNLLDYDDLI
YYTEKLLNNNTTHEWLLHKLENEIKHILVDEAQDTSPPQWNIITTLITAFNAADKPSNSTFIVGDDKQSIFSFQGSDLHN
FSLVKEQLKANLTSANKKFKNITLEFSYRSCAEILQFTHNVLKNIKSNYPSLFLADNPLISSCRTHQGLVTIWPLVMSEK
QEELFWALPEDYEHSKSAADLLIEKIVNFIQEQIESKEILPSTVSTISEKDFIILVRKRDEFSNNLIKELSNAKLNVEIS
DRINIKENLTIMDLMSVAKFVLLPDDDLNLAGLLKSPIIGINEKQLYVLLINKNDNSLWDNLSACEAIYAKLNALIEIYK
ISTVENFFDLVVHNLNLRELYDDDSDDMINELLTLSKHYANDIDNSLQGFVAWFENNDIYIKRDMEHSDKIRVMTVHGSK
GLEAPIVILCDSTTLPVSSNQFIWDDKGEMFFSANIVDTPEFLQELKEAAKLQDLQEYIRLLYVAMTRAKDRLIICGFSN
KSNTPENCWYEIVKQTFD
>Mature_817_residues
SNLQQQASDPNYSVWVSASAGTGKTKILTDRFLRLLITGVEPTNILCLTFTNSAAIEMKARINSKLKHLSLCDAENLENE
LFLMSGNKPLPQEIENAKTLYDKILKSNEPLNIYTIHAFCQKILNTFPLEAGITPEFKILEETKLQDIFLNIRNEIYLSD
EHNDFIKILLNRFHEITLQDIFNEIIDQKIKFKKLFTHKTIPNEIYNKRLAFVELNNIYDKVKSLFAEYDLEIEPKEIFF
TKDGKKRKSLLSKELRRKYPKLLLELEKIISEIYRLDELHRIEKLEYHTNLLTKLAHIILKKYDSYKEENNLLDYDDLIY
YTEKLLNNNTTHEWLLHKLENEIKHILVDEAQDTSPPQWNIITTLITAFNAADKPSNSTFIVGDDKQSIFSFQGSDLHNF
SLVKEQLKANLTSANKKFKNITLEFSYRSCAEILQFTHNVLKNIKSNYPSLFLADNPLISSCRTHQGLVTIWPLVMSEKQ
EELFWALPEDYEHSKSAADLLIEKIVNFIQEQIESKEILPSTVSTISEKDFIILVRKRDEFSNNLIKELSNAKLNVEISD
RINIKENLTIMDLMSVAKFVLLPDDDLNLAGLLKSPIIGINEKQLYVLLINKNDNSLWDNLSACEAIYAKLNALIEIYKI
STVENFFDLVVHNLNLRELYDDDSDDMINELLTLSKHYANDIDNSLQGFVAWFENNDIYIKRDMEHSDKIRVMTVHGSKG
LEAPIVILCDSTTLPVSSNQFIWDDKGEMFFSANIVDTPEFLQELKEAAKLQDLQEYIRLLYVAMTRAKDRLIICGFSNK
SNTPENCWYEIVKQTFD

Specific function: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domai

COG id: COG1074

COG function: function code L; ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789183, Length=504, Percent_Identity=22.0238095238095, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI48994965, Length=458, Percent_Identity=25.9825327510917, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014152
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR011604
- InterPro:   IPR014016
- InterPro:   IPR011335 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 94874; Mature: 94743

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLQQQASDPNYSVWVSASAGTGKTKILTDRFLRLLITGVEPTNILCLTFTNSAAIEMK
CCCCHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEH
ARINSKLKHLSLCDAENLENELFLMSGNKPLPQEIENAKTLYDKILKSNEPLNIYTIHAF
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHH
CQKILNTFPLEAGITPEFKILEETKLQDIFLNIRNEIYLSDEHNDFIKILLNRFHEITLQ
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHH
DIFNEIIDQKIKFKKLFTHKTIPNEIYNKRLAFVELNNIYDKVKSLFAEYDLEIEPKEIF
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEEEHHHHHHHHHHHHHHCCCCCCCCEEE
FTKDGKKRKSLLSKELRRKYPKLLLELEKIISEIYRLDELHRIEKLEYHTNLLTKLAHII
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKYDSYKEENNLLDYDDLIYYTEKLLNNNTTHEWLLHKLENEIKHILVDEAQDTSPPQW
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NIITTLITAFNAADKPSNSTFIVGDDKQSIFSFQGSDLHNFSLVKEQLKANLTSANKKFK
HHHHHHHHHHCCCCCCCCCEEEEECCHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCHHH
NITLEFSYRSCAEILQFTHNVLKNIKSNYPSLFLADNPLISSCRTHQGLVTIWPLVMSEK
EEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHCCC
QEELFWALPEDYEHSKSAADLLIEKIVNFIQEQIESKEILPSTVSTISEKDFIILVRKRD
CHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCC
EFSNNLIKELSNAKLNVEISDRINIKENLTIMDLMSVAKFVLLPDDDLNLAGLLKSPIIG
HHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHEEECCCCCCCHHHHHHCCCCC
INEKQLYVLLINKNDNSLWDNLSACEAIYAKLNALIEIYKISTVENFFDLVVHNLNLREL
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
YDDDSDDMINELLTLSKHYANDIDNSLQGFVAWFENNDIYIKRDMEHSDKIRVMTVHGSK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCCCCCEEEEEEECCC
GLEAPIVILCDSTTLPVSSNQFIWDDKGEMFFSANIVDTPEFLQELKEAAKLQDLQEYIR
CCCCCEEEEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LLYVAMTRAKDRLIICGFSNKSNTPENCWYEIVKQTFD
HHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNLQQQASDPNYSVWVSASAGTGKTKILTDRFLRLLITGVEPTNILCLTFTNSAAIEMK
CCCHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEH
ARINSKLKHLSLCDAENLENELFLMSGNKPLPQEIENAKTLYDKILKSNEPLNIYTIHAF
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHH
CQKILNTFPLEAGITPEFKILEETKLQDIFLNIRNEIYLSDEHNDFIKILLNRFHEITLQ
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHH
DIFNEIIDQKIKFKKLFTHKTIPNEIYNKRLAFVELNNIYDKVKSLFAEYDLEIEPKEIF
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEEEHHHHHHHHHHHHHHCCCCCCCCEEE
FTKDGKKRKSLLSKELRRKYPKLLLELEKIISEIYRLDELHRIEKLEYHTNLLTKLAHII
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKYDSYKEENNLLDYDDLIYYTEKLLNNNTTHEWLLHKLENEIKHILVDEAQDTSPPQW
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NIITTLITAFNAADKPSNSTFIVGDDKQSIFSFQGSDLHNFSLVKEQLKANLTSANKKFK
HHHHHHHHHHCCCCCCCCCEEEEECCHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCHHH
NITLEFSYRSCAEILQFTHNVLKNIKSNYPSLFLADNPLISSCRTHQGLVTIWPLVMSEK
EEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHCCC
QEELFWALPEDYEHSKSAADLLIEKIVNFIQEQIESKEILPSTVSTISEKDFIILVRKRD
CHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCC
EFSNNLIKELSNAKLNVEISDRINIKENLTIMDLMSVAKFVLLPDDDLNLAGLLKSPIIG
HHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHEEECCCCCCCHHHHHHCCCCC
INEKQLYVLLINKNDNSLWDNLSACEAIYAKLNALIEIYKISTVENFFDLVVHNLNLREL
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
YDDDSDDMINELLTLSKHYANDIDNSLQGFVAWFENNDIYIKRDMEHSDKIRVMTVHGSK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCCCCCEEEEEEECCC
GLEAPIVILCDSTTLPVSSNQFIWDDKGEMFFSANIVDTPEFLQELKEAAKLQDLQEYIR
CCCCCEEEEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LLYVAMTRAKDRLIICGFSNKSNTPENCWYEIVKQTFD
HHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA