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The map label for this gene is lolC [H]

Identifier: 157826123

GI number: 157826123

Start: 972263

End: 973510

Strand: Direct

Name: lolC [H]

Synonym: A1C_05490

Alternate gene names: 157826123

Gene position: 972263-973510 (Clockwise)

Preceding gene: 157826122

Following gene: 157826124

Centisome position: 78.98

GC content: 30.53

Gene sequence:

>1248_bases
ATGATCAATAACAACTTTATTTTCAATATAGCTTTCAGATATTTTAGAGCTAAGAAAAACGAAAAATTTGTTTCTATTAT
TTCTGCATTTTCTTTAGTAGGCGTAATGATTGGCGTTGCAGCATTGATAGTAGTCATGTCCGTTATGAACGGTTTTCATA
TAGAGCTTACTAAAAATATTATCGGGTTAAATGGGGATATAGTAATAAATCGGCAAGGCGCTAGTATTGATAACTATGAA
GAAATTAAAACTAAACTCCTAAAACAAGATTACGTAAAACATGTAACATTCATTGCTCACGGTCAAGCTCTAGCTCTTGG
TAAAAGTAATAATAGCGGTGTGCTTGTTAAAGGCATGAAATTAAAGGATTTAAGTTTAAGAAATGAAATTTTTAAAAATG
TAAATTTTGGTAGTTTTGATAATTTTTACGGCAAAAACGTAATAGCACTCGGAGAACAATTAGCAAGCAATTTAGGAGTA
ACTGTTGGGGATAAGATTAGATTAATTTCACCACATTCGGTTTCTACCGCCTTTGGCAGTATGCCAAGATCAAAAGAATT
TAAAGTTATCGCAATTTTCAATAGCGGTATGTATGATTATGATTTGACAACGATATTAATGCCGCTTACTGCAGCACAAA
ATTTCTTATCTCTCGGCAACGATATTAATTTAATCGAAATTAATAGTCTAGACCCAGATAAAGCTCTCACATATTCATAT
AAAATACAATCATTATTAGGTCCAAACCTATACGTATTTAATTGGCAAACCCTAAATTCACAATTTTTAAGTGCCCTTGC
TGTTGAGCGTACGGCTATGTTTACTATTCTATCTTTAATTATTACGGTTGCTGCATTTAATATTATTTCAAGCTTATTTA
TGCTTGTTAAAGATAAAACTTCAGATATTGCAATTCTTAGAACTATGGGAGCAAGCACTAAGCAAATAATGCTTATTTTT
ATCTATAACGGAATGTTTATAGGATTACTTGGCACGACACTAGGTATAATTCTTGGTGTTACTTTTTCTTATAATATTCA
AACTATAAAAAATTATTTGGAGCGTATAACAGGTACTAAAATTTTTGAAGCAGCTATTTATTTTCTTTATAGTTTACCGT
CAAAAGTAAGAACTGAGGATATTATTTTAATTACCTCTTTATCTATAATATTGTGTTTTCTTGCAACAATTTATCCTTCT
TATAGAGCCTCAAAATTAAATCCAGTGGATGCCCTAAGATATGAGTAA

Upstream 100 bases:

>100_bases
GTGGCGTCATTGCGAGCGACTACAAGGAGCGTGGCAATCTTCAGGAAATAAAAACTAGATTGCCGCGTCACTCCTCGCAA
TGACAGTTTGGATGTAAAAA

Downstream 100 bases:

>100_bases
TACAATCCTCATTTTAAAAAAAATCTCAAAACATTACAGCCAAGGCAACACTATTGTTAAAGTACTCGATGATCTTAATC
TAACGGTTAATGAAGGTGAA

Product: lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MINNNFIFNIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNIIGLNGDIVINRQGASIDNYE
EIKTKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMKLKDLSLRNEIFKNVNFGSFDNFYGKNVIALGEQLASNLGV
TVGDKIRLISPHSVSTAFGSMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYSY
KIQSLLGPNLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKTSDIAILRTMGASTKQIMLIF
IYNGMFIGLLGTTLGIILGVTFSYNIQTIKNYLERITGTKIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYPS
YRASKLNPVDALRYE

Sequences:

>Translated_415_residues
MINNNFIFNIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNIIGLNGDIVINRQGASIDNYE
EIKTKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMKLKDLSLRNEIFKNVNFGSFDNFYGKNVIALGEQLASNLGV
TVGDKIRLISPHSVSTAFGSMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYSY
KIQSLLGPNLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKTSDIAILRTMGASTKQIMLIF
IYNGMFIGLLGTTLGIILGVTFSYNIQTIKNYLERITGTKIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYPS
YRASKLNPVDALRYE
>Mature_415_residues
MINNNFIFNIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNIIGLNGDIVINRQGASIDNYE
EIKTKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMKLKDLSLRNEIFKNVNFGSFDNFYGKNVIALGEQLASNLGV
TVGDKIRLISPHSVSTAFGSMPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYSY
KIQSLLGPNLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKTSDIAILRTMGASTKQIMLIF
IYNGMFIGLLGTTLGIILGVTFSYNIQTIKNYLERITGTKIFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYPS
YRASKLNPVDALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=413, Percent_Identity=33.1719128329298, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787362, Length=413, Percent_Identity=30.2663438256659, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46160; Mature: 46160

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINNNFIFNIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNI
CCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCE
IGLNGDIVINRQGASIDNYEEIKTKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMK
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCEEEECCE
LKDLSLRNEIFKNVNFGSFDNFYGKNVIALGEQLASNLGVTVGDKIRLISPHSVSTAFGS
ECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCEEEEECCCCHHHHHCC
MPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYSY
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEEE
KIQSLLGPNLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKT
EHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SDIAILRTMGASTKQIMLIFIYNGMFIGLLGTTLGIILGVTFSYNIQTIKNYLERITGTK
CCEEEEEECCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCH
IFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYPSYRASKLNPVDALRYE
HHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MINNNFIFNIAFRYFRAKKNEKFVSIISAFSLVGVMIGVAALIVVMSVMNGFHIELTKNI
CCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCE
IGLNGDIVINRQGASIDNYEEIKTKLLKQDYVKHVTFIAHGQALALGKSNNSGVLVKGMK
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCEEEECCE
LKDLSLRNEIFKNVNFGSFDNFYGKNVIALGEQLASNLGVTVGDKIRLISPHSVSTAFGS
ECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECCEEEEECCCCHHHHHCC
MPRSKEFKVIAIFNSGMYDYDLTTILMPLTAAQNFLSLGNDINLIEINSLDPDKALTYSY
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEEE
KIQSLLGPNLYVFNWQTLNSQFLSALAVERTAMFTILSLIITVAAFNIISSLFMLVKDKT
EHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SDIAILRTMGASTKQIMLIFIYNGMFIGLLGTTLGIILGVTFSYNIQTIKNYLERITGTK
CCEEEEEECCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCH
IFEAAIYFLYSLPSKVRTEDIILITSLSIILCFLATIYPSYRASKLNPVDALRYE
HHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]