Click here to switch to the map view.

The map label for this gene is ydgK [H]

Identifier: 157826122

GI number: 157826122

Start: 970979

End: 972154

Strand: Direct

Name: ydgK [H]

Synonym: A1C_05485

Alternate gene names: 157826122

Gene position: 970979-972154 (Clockwise)

Preceding gene: 157826121

Following gene: 157826123

Centisome position: 78.87

GC content: 31.89

Gene sequence:

>1176_bases
ATGAAATTACTTATTACCGTAATCATCATGGAAATACTCGCAGGCGCGGAAATAGATTTATTCGTTCCAAGCTTCCCTGA
AATACAAGATACATTCAACCTTTCAACTTTTATGATGGAACTATTACTTGGTGTAAATCTAACCGCTTATTCTATTACTT
CGCTTATAGTCGGTAATTTAGGAGATAGGTACGGACGCAGACCGATTATTATACTCGGTTTACTGATTTTTAATCTTGGT
AGTTTATTTTGTGTATTTGCAAATAATTATGAATCCATATTATTTGGAAGATTTTTGCAAGGATGTGGGATATCATCGGT
TGCAGTGCTAGTATATGTTGTTCTTGCCGATATTTATTCTGTACAAGAGCAGCAAAGATTAATGGGTATTATAAACGGCA
ATGTTGCACTTTCTATGGCAATAGCGCCGGTTATAGGTAGCTATGTCAATTTATTTTGGGGCTGGCGTGGTAATTTTGTT
TTATTGCTTATAGTAGGTTTGACTAGTCTAATTCTTGGTATGTTATTTATTCCGAAAAGAAAAGTTAATAAAAAAATACG
TATTGCCTTAAAAGAATATATACCTATCTTCAAATCACCAAAAGCTATATATTATATACTTACAATGATATTTCTTGAAC
AAGGATATTGGATATTTATTGGGATTGCTCCTATTTTATATATGCAAAATTTAGGTGTAACTTTAGAATATTTCGGACTT
TATCAAGGAGCAATGGCGGCTTTATTCTCAATTATGAGCTTTTCAAGCGGTTATTGTTTTAAAAAATTTGGAATTAGAAA
TTGCTTCTATTTTGGAGTTATATTTATAATACTATTCCTACTAGGCAATAGTATATTAGTTATCTATAATATTAATCATC
CTTTAACTATAACAATAGTTACTTTATTATTATCTCTTGGTGTGATATATCCGATTAACATATTATGGCCACTGCTTTTA
GAAGCTATTCCGGACGGCAAAGCTCGAATGACGGCTATGTTTACTGCGGCTAGATTGATTTTAACGGCATTTGGGTTGCA
AGTAGTAGGATTGTTATATAACGGTACTTTTAACCCTATTTGCATTACTATATCCATTGTTACGCTATTTGGGTTAGTAA
CATTACCTAAATTATTTAAGTACGATCAAGTCTTTGAGATTTCTAATAGGGTATAG

Upstream 100 bases:

>100_bases
CACGCGATCAAATTGCAGGATGACATGGATAGAAGCGATCCACGCAGCAATGCCTCGCTGGCATGATATCGTCAACACAA
CCTCAAACTGACAATTACTT

Downstream 100 bases:

>100_bases
AGGCCTTTGTGGCGTCATTGCGAGCGACTACAAGGAGCGTGGCAATCTTCAGGAAATAAAAACTAGATTGCCGCGTCACT
CCTCGCAATGACAGTTTGGA

Product: bicyclomycin resistance protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKLLITVIIMEILAGAEIDLFVPSFPEIQDTFNLSTFMMELLLGVNLTAYSITSLIVGNLGDRYGRRPIIILGLLIFNLG
SLFCVFANNYESILFGRFLQGCGISSVAVLVYVVLADIYSVQEQQRLMGIINGNVALSMAIAPVIGSYVNLFWGWRGNFV
LLLIVGLTSLILGMLFIPKRKVNKKIRIALKEYIPIFKSPKAIYYILTMIFLEQGYWIFIGIAPILYMQNLGVTLEYFGL
YQGAMAALFSIMSFSSGYCFKKFGIRNCFYFGVIFIILFLLGNSILVIYNINHPLTITIVTLLLSLGVIYPINILWPLLL
EAIPDGKARMTAMFTAARLILTAFGLQVVGLLYNGTFNPICITISIVTLFGLVTLPKLFKYDQVFEISNRV

Sequences:

>Translated_391_residues
MKLLITVIIMEILAGAEIDLFVPSFPEIQDTFNLSTFMMELLLGVNLTAYSITSLIVGNLGDRYGRRPIIILGLLIFNLG
SLFCVFANNYESILFGRFLQGCGISSVAVLVYVVLADIYSVQEQQRLMGIINGNVALSMAIAPVIGSYVNLFWGWRGNFV
LLLIVGLTSLILGMLFIPKRKVNKKIRIALKEYIPIFKSPKAIYYILTMIFLEQGYWIFIGIAPILYMQNLGVTLEYFGL
YQGAMAALFSIMSFSSGYCFKKFGIRNCFYFGVIFIILFLLGNSILVIYNINHPLTITIVTLLLSLGVIYPINILWPLLL
EAIPDGKARMTAMFTAARLILTAFGLQVVGLLYNGTFNPICITISIVTLFGLVTLPKLFKYDQVFEISNRV
>Mature_391_residues
MKLLITVIIMEILAGAEIDLFVPSFPEIQDTFNLSTFMMELLLGVNLTAYSITSLIVGNLGDRYGRRPIIILGLLIFNLG
SLFCVFANNYESILFGRFLQGCGISSVAVLVYVVLADIYSVQEQQRLMGIINGNVALSMAIAPVIGSYVNLFWGWRGNFV
LLLIVGLTSLILGMLFIPKRKVNKKIRIALKEYIPIFKSPKAIYYILTMIFLEQGYWIFIGIAPILYMQNLGVTLEYFGL
YQGAMAALFSIMSFSSGYCFKKFGIRNCFYFGVIFIILFLLGNSILVIYNINHPLTITIVTLLLSLGVIYPINILWPLLL
EAIPDGKARMTAMFTAARLILTAFGLQVVGLLYNGTFNPICITISIVTLFGLVTLPKLFKYDQVFEISNRV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=164, Percent_Identity=30.4878048780488, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788509, Length=264, Percent_Identity=22.7272727272727, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790146, Length=271, Percent_Identity=23.6162361623616, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790794, Length=195, Percent_Identity=24.6153846153846, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082312, Length=192, Percent_Identity=23.9583333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081738, Length=169, Percent_Identity=26.6272189349112, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324264, Length=183, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322071, Length=162, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43742; Mature: 43742

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLITVIIMEILAGAEIDLFVPSFPEIQDTFNLSTFMMELLLGVNLTAYSITSLIVGNL
CHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GDRYGRRPIIILGLLIFNLGSLFCVFANNYESILFGRFLQGCGISSVAVLVYVVLADIYS
CHHHCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VQEQQRLMGIINGNVALSMAIAPVIGSYVNLFWGWRGNFVLLLIVGLTSLILGMLFIPKR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
KVNKKIRIALKEYIPIFKSPKAIYYILTMIFLEQGYWIFIGIAPILYMQNLGVTLEYFGL
HHCHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHH
YQGAMAALFSIMSFSSGYCFKKFGIRNCFYFGVIFIILFLLGNSILVIYNINHPLTITIV
HHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHH
TLLLSLGVIYPINILWPLLLEAIPDGKARMTAMFTAARLILTAFGLQVVGLLYNGTFNPI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
CITISIVTLFGLVTLPKLFKYDQVFEISNRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLLITVIIMEILAGAEIDLFVPSFPEIQDTFNLSTFMMELLLGVNLTAYSITSLIVGNL
CHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
GDRYGRRPIIILGLLIFNLGSLFCVFANNYESILFGRFLQGCGISSVAVLVYVVLADIYS
CHHHCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VQEQQRLMGIINGNVALSMAIAPVIGSYVNLFWGWRGNFVLLLIVGLTSLILGMLFIPKR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
KVNKKIRIALKEYIPIFKSPKAIYYILTMIFLEQGYWIFIGIAPILYMQNLGVTLEYFGL
HHCHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHH
YQGAMAALFSIMSFSSGYCFKKFGIRNCFYFGVIFIILFLLGNSILVIYNINHPLTITIV
HHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHH
TLLLSLGVIYPINILWPLLLEAIPDGKARMTAMFTAARLILTAFGLQVVGLLYNGTFNPI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
CITISIVTLFGLVTLPKLFKYDQVFEISNRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9202461 [H]