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The map label for this gene is ccmE

Identifier: 157825969

GI number: 157825969

Start: 824579

End: 824965

Strand: Direct

Name: ccmE

Synonym: A1C_04575

Alternate gene names: 157825969

Gene position: 824579-824965 (Clockwise)

Preceding gene: 157825968

Following gene: 157825970

Centisome position: 66.98

GC content: 32.82

Gene sequence:

>387_bases
ATGCAAAAGAGAGTAAGAAATAGATTAATAACAATAATTATTTGTTTCTGCTCAGCTGCTCTCGGAATTAGTATAATACT
TTACAATTTAGAGAAAAATATAGTATTTTTTTTGCCGCCGTCAAAAATTAATGAGATAGAAGAAGGCAAAGAGTTAAGAG
TAGGCGGGCTTGTTAAAATAGACTCAATCAATAAAATTGCTGCTGATAAGATAAGTTTTGTTATTACCGATAATATTAAG
GATTTAGATATATTATATCAAGGGGTCCTCCCTGCCCTATTTCGTGAAGGACAAGGAATTATTGCCATAGGGCAATTGTT
GGACAGGAAATTTATAGCAAGGCAATTACTTGCAAAGCATGATGAAAATTACAGACCTCCGAGTTAA

Upstream 100 bases:

>100_bases
TATATATTGGTAGCGTATTTATTTACCTTCTTAACCTTATCCATACTATTAATCGTAATTTTTTTAAATTACAAGTCACT
GAAAAATAAACAGAACTTTA

Downstream 100 bases:

>100_bases
AGAACTCGGTGTCATACCGTGGCTTGACCACGGTATCCATAAAAACAACTTAAAACACAAGTTGTTTTTATATTTTTAAC
TAGATGACGTGGTCAAGCCA

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MQKRVRNRLITIIICFCSAALGISIILYNLEKNIVFFLPPSKINEIEEGKELRVGGLVKIDSINKIAADKISFVITDNIK
DLDILYQGVLPALFREGQGIIAIGQLLDRKFIARQLLAKHDENYRPPS

Sequences:

>Translated_128_residues
MQKRVRNRLITIIICFCSAALGISIILYNLEKNIVFFLPPSKINEIEEGKELRVGGLVKIDSINKIAADKISFVITDNIK
DLDILYQGVLPALFREGQGIIAIGQLLDRKFIARQLLAKHDENYRPPS
>Mature_128_residues
MQKRVRNRLITIIICFCSAALGISIILYNLEKNIVFFLPPSKINEIEEGKELRVGGLVKIDSINKIAADKISFVITDNIK
DLDILYQGVLPALFREGQGIIAIGQLLDRKFIARQLLAKHDENYRPPS

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=137, Percent_Identity=40.1459854014599, Blast_Score=95, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_RICAH (A8GP56)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493689.1
- ProteinModelPortal:   A8GP56
- SMR:   A8GP56
- STRING:   A8GP56
- GeneID:   5645530
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_04575
- NMPDR:   fig|293614.3.peg.852
- eggNOG:   COG2332
- HOGENOM:   HBG296631
- OMA:   ICFCSAC
- ProtClustDB:   PRK13254
- BioCyc:   RAKA293614:A1C_04575-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 14449; Mature: 14449

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: BINDING 120-120

Signals:

None

Transmembrane regions:

HASH(0x12b49b00)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRVRNRLITIIICFCSAALGISIILYNLEKNIVFFLPPSKINEIEEGKELRVGGLVKI
CCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHHCCCEEEECCEEEE
DSINKIAADKISFVITDNIKDLDILYQGVLPALFREGQGIIAIGQLLDRKFIARQLLAKH
CCCCHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHC
DENYRPPS
CCCCCCCH
>Mature Secondary Structure
MQKRVRNRLITIIICFCSAALGISIILYNLEKNIVFFLPPSKINEIEEGKELRVGGLVKI
CCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHHCCCEEEECCEEEE
DSINKIAADKISFVITDNIKDLDILYQGVLPALFREGQGIIAIGQLLDRKFIARQLLAKH
CCCCHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHC
DENYRPPS
CCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA