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The map label for this gene is secD [H]

Identifier: 157825967

GI number: 157825967

Start: 822061

End: 823617

Strand: Direct

Name: secD [H]

Synonym: A1C_04565

Alternate gene names: 157825967

Gene position: 822061-823617 (Clockwise)

Preceding gene: 157825966

Following gene: 157825968

Centisome position: 66.78

GC content: 34.55

Gene sequence:

>1557_bases
GTGCAAAATCTTCCTAAGTGGAAAATTTTTCTTTCAATTATATGTACGGTTTTTGCGGTTATTTGTGCCTTACCTAATTT
TATGCATATAAACTCTAAGTTTCTGCCTCATGATTCAGTAAATTTAGGGCTTGACCTTAGAGGAGGAGCGCATTTATTAC
TCGATGTTGATTTTGATACCTACTTAAATGATTTAATGGAAAATCTTGCTGATACTTTACGCAAAAATTTTCGCAAGGAT
AAAATCGGCTATAAAAATCTGTTAGTTAGACAAAATAATATTCAATTAGAAGTAAGATCGCCTGAGGAATTAAAACCTTT
AAAGAAAATAATTAATAAAATCGATCCGGAAATTATCACTGACGTAAATAAAAATAAAATAAAGCTTAGCTACAGCGAAT
CTAGATTAAATGACTTACTTAATAAGGTAGTAGACCAATCTATTGAGATCGTTCGCATGAGAGTTGATAGTACCGGCACT
AAGGAGCCAACACTACAGAAGCAAGGCGATAAGCATATATTACTGCAAGTGCCCGGAGAAGAAAATCCCTCTTACCTGAA
GAATCTATTAGGAAAAACTGCAAAACTAACTTTTCATTTAGTTGATGAAAATGCCAATATCGAAGAAGCGGTAAAAGGAC
ATGTCCCTGTCGGTTCAATGCTAGTTAAGGGAGCTAACGAAAGTCATGGGGAGTATTATGTAGTTATAAAGAAAAAAGTT
GTTTTAGGTGGGGATCAACTTACAACTGCTTCAGCTTCTTTTGACCAAAATTCACAAGCGGTAGTTGCCTTTTCTTTCAA
TAATTTAGGTAGTAAAATATTCGGTGAAATAACAAAAAATAATATCGGTAAACGCCTTGCTATAGTTTTAGACAATAAAT
TACTAAGTGCTCCAACGATAAACGGAGCGATTATTGGCGGAAGCGGTATAATAACGGGAAATTTTACCGTTGAGTCGGCA
AATGAACTTGCAATATTATTGCGTGCCGGTTCGCTCCCTGCCCCACTTAAAATTATTGAAGAGAGAAGTATAGGTCCAAA
TTTAGGTGCTGACTCTATAGAGTCGGGCAAAAAGGCATGGCTTATAGGATTTATAGCAGTTTGTATATTTATGGTTTGGT
CTTACGGCGTGCTTGGTTTATTCGCCAATATAGCATTAAGCCTTGCATTGTTATATATTCTAGCTTTACTTTCACTTTTC
CAAGCTACTTTAACTATGCCGGGAATTGCAGGAATAATACTAACTATGGGTATGGCTGTTGATGCTAATGTATTGATTTA
CGAAAGGATTAAAGAAGAATTGCATAAAGGTGTTTCTAATCTTTATGCCATTAGAACCGGTTTTGAATTTGCATTTGCTA
CTATCCTTGATTCTAACTTAACTACGTTAATTGTTGCTTTTTTACTTTATATATTCGGAGTCGGGGCAATAAAAGGTTTT
GCCGTTGCATTAACGATCGGGATTATATCTTCAATGTTTTCGGCAATGATCATTACTAAATTGTTAATAGATATTTGGGT
AAAATATTTTAAACCTAAGAAATTAGGTTTGGTGTAA

Upstream 100 bases:

>100_bases
CGTATTAAAGCTTTAAAAAGTGCTATTATCGATATAACTAGTCGTACAAAAAAAGTAGCAGTAAAAAAAGAAAATAACAA
AAAAGATAAGAGGGTAAACG

Downstream 100 bases:

>100_bases
AAGAGTAGACTTTGTGGTAGTCGTAGTTTTAACGTCATTGCGAGGAAAAACTTGCGTTGTTGCATAGCTCATTTATGTCA
TTCCCGCGTAGGCGGTAATC

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MQNLPKWKIFLSIICTVFAVICALPNFMHINSKFLPHDSVNLGLDLRGGAHLLLDVDFDTYLNDLMENLADTLRKNFRKD
KIGYKNLLVRQNNIQLEVRSPEELKPLKKIINKIDPEIITDVNKNKIKLSYSESRLNDLLNKVVDQSIEIVRMRVDSTGT
KEPTLQKQGDKHILLQVPGEENPSYLKNLLGKTAKLTFHLVDENANIEEAVKGHVPVGSMLVKGANESHGEYYVVIKKKV
VLGGDQLTTASASFDQNSQAVVAFSFNNLGSKIFGEITKNNIGKRLAIVLDNKLLSAPTINGAIIGGSGIITGNFTVESA
NELAILLRAGSLPAPLKIIEERSIGPNLGADSIESGKKAWLIGFIAVCIFMVWSYGVLGLFANIALSLALLYILALLSLF
QATLTMPGIAGIILTMGMAVDANVLIYERIKEELHKGVSNLYAIRTGFEFAFATILDSNLTTLIVAFLLYIFGVGAIKGF
AVALTIGIISSMFSAMIITKLLIDIWVKYFKPKKLGLV

Sequences:

>Translated_518_residues
MQNLPKWKIFLSIICTVFAVICALPNFMHINSKFLPHDSVNLGLDLRGGAHLLLDVDFDTYLNDLMENLADTLRKNFRKD
KIGYKNLLVRQNNIQLEVRSPEELKPLKKIINKIDPEIITDVNKNKIKLSYSESRLNDLLNKVVDQSIEIVRMRVDSTGT
KEPTLQKQGDKHILLQVPGEENPSYLKNLLGKTAKLTFHLVDENANIEEAVKGHVPVGSMLVKGANESHGEYYVVIKKKV
VLGGDQLTTASASFDQNSQAVVAFSFNNLGSKIFGEITKNNIGKRLAIVLDNKLLSAPTINGAIIGGSGIITGNFTVESA
NELAILLRAGSLPAPLKIIEERSIGPNLGADSIESGKKAWLIGFIAVCIFMVWSYGVLGLFANIALSLALLYILALLSLF
QATLTMPGIAGIILTMGMAVDANVLIYERIKEELHKGVSNLYAIRTGFEFAFATILDSNLTTLIVAFLLYIFGVGAIKGF
AVALTIGIISSMFSAMIITKLLIDIWVKYFKPKKLGLV
>Mature_518_residues
MQNLPKWKIFLSIICTVFAVICALPNFMHINSKFLPHDSVNLGLDLRGGAHLLLDVDFDTYLNDLMENLADTLRKNFRKD
KIGYKNLLVRQNNIQLEVRSPEELKPLKKIINKIDPEIITDVNKNKIKLSYSESRLNDLLNKVVDQSIEIVRMRVDSTGT
KEPTLQKQGDKHILLQVPGEENPSYLKNLLGKTAKLTFHLVDENANIEEAVKGHVPVGSMLVKGANESHGEYYVVIKKKV
VLGGDQLTTASASFDQNSQAVVAFSFNNLGSKIFGEITKNNIGKRLAIVLDNKLLSAPTINGAIIGGSGIITGNFTVESA
NELAILLRAGSLPAPLKIIEERSIGPNLGADSIESGKKAWLIGFIAVCIFMVWSYGVLGLFANIALSLALLYILALLSLF
QATLTMPGIAGIILTMGMAVDANVLIYERIKEELHKGVSNLYAIRTGFEFAFATILDSNLTTLIVAFLLYIFGVGAIKGF
AVALTIGIISSMFSAMIITKLLIDIWVKYFKPKKLGLV

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=502, Percent_Identity=38.8446215139442, Blast_Score=319, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 56845; Mature: 56845

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLPKWKIFLSIICTVFAVICALPNFMHINSKFLPHDSVNLGLDLRGGAHLLLDVDFDT
CCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCEEEEEEECHHH
YLNDLMENLADTLRKNFRKDKIGYKNLLVRQNNIQLEVRSPEELKPLKKIINKIDPEIIT
HHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCEEEEECCCHHHHHHHHHHHHHCCHHCC
DVNKNKIKLSYSESRLNDLLNKVVDQSIEIVRMRVDSTGTKEPTLQKQGDKHILLQVPGE
CCCCCEEEEEECHHHHHHHHHHHHHCHHHEEEEEECCCCCCCCCHHCCCCCEEEEECCCC
ENPSYLKNLLGKTAKLTFHLVDENANIEEAVKGHVPVGSMLVKGANESHGEYYVVIKKKV
CCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCHHHHHEECCCCCCCCEEEEEEEEE
VLGGDQLTTASASFDQNSQAVVAFSFNNLGSKIFGEITKNNIGKRLAIVLDNKLLSAPTI
EECCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEECCCCC
NGAIIGGSGIITGNFTVESANELAILLRAGSLPAPLKIIEERSIGPNLGADSIESGKKAW
CCEEECCCEEEEECEEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHH
LIGFIAVCIFMVWSYGVLGLFANIALSLALLYILALLSLFQATLTMPGIAGIILTMGMAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
DANVLIYERIKEELHKGVSNLYAIRTGFEFAFATILDSNLTTLIVAFLLYIFGVGAIKGF
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AVALTIGIISSMFSAMIITKLLIDIWVKYFKPKKLGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQNLPKWKIFLSIICTVFAVICALPNFMHINSKFLPHDSVNLGLDLRGGAHLLLDVDFDT
CCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEECCCEEEEEEECHHH
YLNDLMENLADTLRKNFRKDKIGYKNLLVRQNNIQLEVRSPEELKPLKKIINKIDPEIIT
HHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCEEEEECCCHHHHHHHHHHHHHCCHHCC
DVNKNKIKLSYSESRLNDLLNKVVDQSIEIVRMRVDSTGTKEPTLQKQGDKHILLQVPGE
CCCCCEEEEEECHHHHHHHHHHHHHCHHHEEEEEECCCCCCCCCHHCCCCCEEEEECCCC
ENPSYLKNLLGKTAKLTFHLVDENANIEEAVKGHVPVGSMLVKGANESHGEYYVVIKKKV
CCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCHHHHHEECCCCCCCCEEEEEEEEE
VLGGDQLTTASASFDQNSQAVVAFSFNNLGSKIFGEITKNNIGKRLAIVLDNKLLSAPTI
EECCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCEECCCCC
NGAIIGGSGIITGNFTVESANELAILLRAGSLPAPLKIIEERSIGPNLGADSIESGKKAW
CCEEECCCEEEEECEEEECCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHH
LIGFIAVCIFMVWSYGVLGLFANIALSLALLYILALLSLFQATLTMPGIAGIILTMGMAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
DANVLIYERIKEELHKGVSNLYAIRTGFEFAFATILDSNLTTLIVAFLLYIFGVGAIKGF
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AVALTIGIISSMFSAMIITKLLIDIWVKYFKPKKLGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]