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The map label for this gene is acpS

Identifier: 157825957

GI number: 157825957

Start: 809625

End: 810005

Strand: Reverse

Name: acpS

Synonym: A1C_04495

Alternate gene names: 157825957

Gene position: 810005-809625 (Counterclockwise)

Preceding gene: 157825958

Following gene: 157825955

Centisome position: 65.8

GC content: 32.28

Gene sequence:

>381_bases
ATGCTTATCGGTGTCGGTACTGATATAGTACAAATTCTTAGAATCGAAAAAATATTGCATTTATATCCAGAACTTTTTGC
TAAAAGAATTCTAGCCTCAAAAGAATTAAGACAGTTTGCTTTATTAAATAAAACAAGTCATGCTACTTTTTTAGCAAAAC
GTTTTGCTGCTAAAGAAGCTGTTAGTAAAGCTTTTGGCATTGGTATCGGTCAAGGCATAAACTTTAAAGACATTACTATA
CTCAATGATGATTTAGGCAAACCTATAGTAGAAGTTAGTGCAAGCTATACAAAAAAATACTCTTCTTTTAATATTCACCT
TTCTCTTTCTGATGATTATCCTGTATGCGTGGCGTTTGCCATAGTTGAGAGTAGTTGTTAG

Upstream 100 bases:

>100_bases
TGAGTACTTATCTGAAGTTTGTATAACGGAAGATTATTCTGATTTAGATGATCAAATCTTTATTGATGAGAATGGCGAAG
ATTATGACCCCGATAAGTAA

Downstream 100 bases:

>100_bases
GTGTAATTCTTGGGTAGGACCGATCTGTTATTGAGAGTAGGCATAGACCGTTGTGTTGCATGTGGTTCAAAAAATCTACC
CGATGTCATTCCCGCAAAGG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MLIGVGTDIVQILRIEKILHLYPELFAKRILASKELRQFALLNKTSHATFLAKRFAAKEAVSKAFGIGIGQGINFKDITI
LNDDLGKPIVEVSASYTKKYSSFNIHLSLSDDYPVCVAFAIVESSC

Sequences:

>Translated_126_residues
MLIGVGTDIVQILRIEKILHLYPELFAKRILASKELRQFALLNKTSHATFLAKRFAAKEAVSKAFGIGIGQGINFKDITI
LNDDLGKPIVEVSASYTKKYSSFNIHLSLSDDYPVCVAFAIVESSC
>Mature_126_residues
MLIGVGTDIVQILRIEKILHLYPELFAKRILASKELRQFALLNKTSHATFLAKRFAAKEAVSKAFGIGIGQGINFKDITI
LNDDLGKPIVEVSASYTKKYSSFNIHLSLSDDYPVCVAFAIVESSC

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=39.84375, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_RICAH (A8GP44)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493677.1
- ProteinModelPortal:   A8GP44
- SMR:   A8GP44
- STRING:   A8GP44
- GeneID:   5645343
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_04495
- NMPDR:   fig|293614.3.peg.839
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   RAKA293614:A1C_04495-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13906; Mature: 13906

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGVGTDIVQILRIEKILHLYPELFAKRILASKELRQFALLNKTSHATFLAKRFAAKEA
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VSKAFGIGIGQGINFKDITILNDDLGKPIVEVSASYTKKYSSFNIHLSLSDDYPVCVAFA
HHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVESSC
HHHCCC
>Mature Secondary Structure
MLIGVGTDIVQILRIEKILHLYPELFAKRILASKELRQFALLNKTSHATFLAKRFAAKEA
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VSKAFGIGIGQGINFKDITILNDDLGKPIVEVSASYTKKYSSFNIHLSLSDDYPVCVAFA
HHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVESSC
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA