Click here to switch to the map view.

The map label for this gene is bioC [C]

Identifier: 157825889

GI number: 157825889

Start: 747786

End: 748466

Strand: Reverse

Name: bioC [C]

Synonym: A1C_04140

Alternate gene names: 157825889

Gene position: 748466-747786 (Counterclockwise)

Preceding gene: 157825890

Following gene: 157825888

Centisome position: 60.8

GC content: 29.37

Gene sequence:

>681_bases
ATGATTGATAAGGATGTGTCGGATATTCTAGAAATATCGGCTAAGTGTGGTTATCTTACGAGCTTACTAAAAAATGCTTA
TCGAAGTGCCAATATTACCGTAACAGATATGTCGCCTTTATTGCTTGATTCTTTTGAGTATAATCACAAATTGTTAATTG
ATGATGAAGATTTAGCATTTCCAAAAGACTCTTTTGATTTAATTATTTATTCATTAGGGTTACACTGGATAAATGATGTG
CAGAGTTTTCTGTCTAATATAAAAACATTTTTAAAACCTGAGGGTATTTTTATCGGTAATTTTGTCGGAGGAAATAGTTT
AAAGAATTTACGTAAATCTTTAATAGATGCTGAAACAGCAAGTGATTTTAAACACTATCCTCATATTTCTCCCTTTATTC
ATTTTGACCATGTCCCAACGCTATTATTGCAAGCAGGATTTTCCGAAGTAATTATTGACTATGAAAATATAGAGCTAAAA
TTTGATCATCTTGTAGCTTTAATGAGGGAAATAAAAAATATCGGTGAGTCAAATTCACTAAATTCTAGTCATAATTACGC
TATTTCTAAAAAGATGTTTTCTTTACTACAAAATTATACCCACGGCTTTGAAGATAATATTAATTTAATTAGTTTTATTG
CTGCACCCAATAAGAATAGTATAAGATTAAAGTTGTTATAG

Upstream 100 bases:

>100_bases
CAGATTAAAGCTAAAAAATCACCGAAATAATGCAGTAGCGGGAATAAATAACAGCTTATTTATCAAGCATGCAGCTAATG
ATATAATCAGTCGATTAGGG

Downstream 100 bases:

>100_bases
GGCTTATAATATTGTATTGTTGCCATGTCGTGGTTTGAATATTGTTATCCCGCGCCTTGATTTTGGGATCCAGTCTTTTT
TAATTTTTTTCTGGATACCG

Product: biotin synthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIDKDVSDILEISAKCGYLTSLLKNAYRSANITVTDMSPLLLDSFEYNHKLLIDDEDLAFPKDSFDLIIYSLGLHWINDV
QSFLSNIKTFLKPEGIFIGNFVGGNSLKNLRKSLIDAETASDFKHYPHISPFIHFDHVPTLLLQAGFSEVIIDYENIELK
FDHLVALMREIKNIGESNSLNSSHNYAISKKMFSLLQNYTHGFEDNINLISFIAAPNKNSIRLKLL

Sequences:

>Translated_226_residues
MIDKDVSDILEISAKCGYLTSLLKNAYRSANITVTDMSPLLLDSFEYNHKLLIDDEDLAFPKDSFDLIIYSLGLHWINDV
QSFLSNIKTFLKPEGIFIGNFVGGNSLKNLRKSLIDAETASDFKHYPHISPFIHFDHVPTLLLQAGFSEVIIDYENIELK
FDHLVALMREIKNIGESNSLNSSHNYAISKKMFSLLQNYTHGFEDNINLISFIAAPNKNSIRLKLL
>Mature_226_residues
MIDKDVSDILEISAKCGYLTSLLKNAYRSANITVTDMSPLLLDSFEYNHKLLIDDEDLAFPKDSFDLIIYSLGLHWINDV
QSFLSNIKTFLKPEGIFIGNFVGGNSLKNLRKSLIDAETASDFKHYPHISPFIHFDHVPTLLLQAGFSEVIIDYENIELK
FDHLVALMREIKNIGESNSLNSSHNYAISKKMFSLLQNYTHGFEDNINLISFIAAPNKNSIRLKLL

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=129, Percent_Identity=41.0852713178295, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI86792933, Length=108, Percent_Identity=40.7407407407407, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17535003, Length=180, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922210, Length=183, Percent_Identity=34.4262295081967, Blast_Score=107, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 25674; Mature: 25674

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKDVSDILEISAKCGYLTSLLKNAYRSANITVTDMSPLLLDSFEYNHKLLIDDEDLAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCEEEECCCCCCC
PKDSFDLIIYSLGLHWINDVQSFLSNIKTFLKPEGIFIGNFVGGNSLKNLRKSLIDAETA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
SDFKHYPHISPFIHFDHVPTLLLQAGFSEVIIDYENIELKFDHLVALMREIKNIGESNSL
HHHHCCCCCCCEEEHHHHHHHHHHCCCHHEEEECCCCEEEHHHHHHHHHHHHHCCCCCCC
NSSHNYAISKKMFSLLQNYTHGFEDNINLISFIAAPNKNSIRLKLL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEC
>Mature Secondary Structure
MIDKDVSDILEISAKCGYLTSLLKNAYRSANITVTDMSPLLLDSFEYNHKLLIDDEDLAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCEEEECCCCCCC
PKDSFDLIIYSLGLHWINDVQSFLSNIKTFLKPEGIFIGNFVGGNSLKNLRKSLIDAETA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
SDFKHYPHISPFIHFDHVPTLLLQAGFSEVIIDYENIELKFDHLVALMREIKNIGESNSL
HHHHCCCCCCCEEEHHHHHHHHHHCCCHHEEEECCCCEEEHHHHHHHHHHHHHCCCCCCC
NSSHNYAISKKMFSLLQNYTHGFEDNINLISFIAAPNKNSIRLKLL
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]