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The map label for this gene is infB [H]

Identifier: 157825874

GI number: 157825874

Start: 732469

End: 734958

Strand: Reverse

Name: infB [H]

Synonym: A1C_04065

Alternate gene names: 157825874

Gene position: 734958-732469 (Counterclockwise)

Preceding gene: 157825875

Following gene: 157825873

Centisome position: 59.7

GC content: 35.82

Gene sequence:

>2490_bases
ATGACGGATAACCAGGAAATCAAACCCAAAAAGTTGACACTTGGCAATTCAAAATTATCGCTTAATAAGTCTTTTGACTC
TCTTACAGGAGCTCAAAGCTTTGTTAATGCTAAATCTAAGACACTAGTAGAAGTTAGAAAAAGCTCTACCGGTAGTACTA
CTACCATTTCATTAAATCAAGAAAGAAATAGTTTAGATCACACTGCTATTGATGCTAATAAGGAAGAATTTAACAGACGT
TTATCTATTCTTAAAAAAGCTGCTGAGCAATCTAAATTAAATGACACTTCACAAATCAGCACTTTAAGTAAACTTGCAAG
TATTAACCAGTCTGCTAACTCAAAAATAGAACCGCTAGAAACTGATAAAGAAGTTGAACAAAAACAGCAAAATAACGAAG
AAAATAAAGTAGAAGTTAGTGCTAAAATCGTTCAAGATAATGAACATATACCGTCACAAATATCTAAAAAGAAAGAAGAA
TCTTTTGTAAAGTCTCCTTTAGTAGGAATGCGAACACGTTACGGTATAGAATTAGAGAAAGAATTAGATAAAACAGCAGA
TAGTAAAGTAGTTGCTCCAAAGATTAAGTTAGAAGAGCCAAAAAAATTCAAAAAAGTCGATCTTTTCAATATGCTCGGCG
ATGACGAAAGCGGTAGAACTAGAAGTCTTGCTTCTATAAAAAGAGCTAGAGAAAAAGAAAAGCGTAAATTAGCATCACAA
GCACCTGAGAAGGTATATAGAGAAGTGACGATACCGGAAGTTATCGGAGTTGGCGATCTTGCAAATGCTATGTCTGAAAG
AGTAGCAGATGTAATTAAGGAATTAATGAAGCTAGGTGTTCTTGCGAATGCAAGCCAAACAATAGATACCGATACAGCGG
AACTAGTCGCAACAAATTTAGGGCATACGGTAAAAAGAGTGCAAGAATCAGATGTTGAAAATGTTTTAATTAGTGATGAT
AAGGTTGAAGATTTGAGAATGCGTGCTCCAGTTGTTACAGTAATGGGGCATGTAGATCACGGAAAAACATCATTACTTGA
CGCTCTTAAATCTACGGATATTGCTGCAAGTGAAACTGGAGGCATTACCCAGCATATCGGAGCTTATAGAGTAACTCTTG
CAGACGGTAGAGCGATTACTTTTATTGATACTCCGGGTCACGAGGCTTTTTCGGAAATGCGGTCAAGAGGTGCTAAAGTA
ACGGATATAGTTATTATAGTGGTTGCAGCAGATGATGGAATCAAAACGCAAACGGTTGAGTCAATTAATCATGCAAAAGC
AGCGGGCGTTCCTATAATTGTAGCTATTAATAAGATTGATAAGCCGGATATTGATATTGAGCGTGTAAAAAACGAATTAT
ATGTCCACGAAATTATAGGCGAAGAGGCAGGGGGTGACGTTATGGTTATTCCTATCTCGGCACTAAAAAAAATTAACTTA
GAGAAACTTGAAGAAGCGATTTTATTAGTTGCAGAAATGAAGGATTTAAAGGCAAGCCCTTTCGGTCCAGCTTCTGGTGT
TGTAATTGAATCGAAAATCGAAAAAGGCAGAGGAACGCTAACCACTATATTAGTTCAACGAGGTACCTTAAGAAATGGTG
ATATTATAATAGCAGGTAGCTCTTACGGTAAAGTTAAAAAGATGACTAATGATAAGGGACTAGAAATAGTGGAAGCAACC
CCATCTGTTCCCGTAGAAATTCAAGGTTTAAACGAAGTACCTTTTGCCGGCGATAAATTTAACGTAGTACAAAATGAGAA
ACAAGCAAAAGATATAGCCGAATATAGAATGCGTCTTGCTAAAGAAAAGAAAATATCTATTGCACCGCGTTCAAGTTTAG
AAGATTTATTTTTAAAAGCTTCCGGTAATAGTAAAATTAAGGAATTACCTTTAATTATTAAAGGTGATGTTCAAGGGTCA
GTTGAAGCTATTTTAGGTAGCTTATTAAAATTACCGAGTGATGCAATAAAGCTTCGTATACTTCATAGCGGTGTAGGTCC
GATAACGGAATCCGATGTATCTCTTGCACATGCTTCTTCAGCTATTATTGTCGGTTTTAACGTTAGAGCAGGGGCAAATG
CTTTAACTGCCGCAGAAAAAGAAAAAGTCGATATTAGATATTATAGTATAATATATAATTTAATTGATGACGTGAAAGCC
ATTATGAGCGGTATGCTTGATCCGATCGTTAGAGAGCAATATATCGGAAGCGTGGAAATTAGACAAATATTTAATATTAC
CAAAGTCGGTAAAATTGCCGGTAGCTATGTAACTAAAGGGATTATTAAGCAAGGAGCGAGCGTACGCTTATTACGTGATA
ATGTAGTCATTCACGAAGGAAAACTCAAAACTTTAAAACGCTTTAAAGATGAAGTTAAAGAAGTTAGAGAAGGATATGAG
TGTGGTATAGCATTTGAAAATTACGAAGATATTAGAGAAGGAGACACAGTTGAAGTTTTTGAGCTAGTTCAAGAACAGAG
ACAATTATAG

Upstream 100 bases:

>100_bases
TTCCCGATTTTGCGCGAATGATAGCTATGTGTACAACATTTCTACGGGAATGATGTAATAAGTAGTAGACAGAAAAAACA
GAAACACAAAGGTTTTAAAT

Downstream 100 bases:

>100_bases
TAGAATTTTTATTATATGTCATTCCCGCTTTTGCAGGGATGACATAAACGAGCCATGCAGGCAACGCAACGTTTCCGCAG
GAATAATATTTAGTAGAATG

Product: translation initiation factor IF-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 829; Mature: 828

Protein sequence:

>829_residues
MTDNQEIKPKKLTLGNSKLSLNKSFDSLTGAQSFVNAKSKTLVEVRKSSTGSTTTISLNQERNSLDHTAIDANKEEFNRR
LSILKKAAEQSKLNDTSQISTLSKLASINQSANSKIEPLETDKEVEQKQQNNEENKVEVSAKIVQDNEHIPSQISKKKEE
SFVKSPLVGMRTRYGIELEKELDKTADSKVVAPKIKLEEPKKFKKVDLFNMLGDDESGRTRSLASIKRAREKEKRKLASQ
APEKVYREVTIPEVIGVGDLANAMSERVADVIKELMKLGVLANASQTIDTDTAELVATNLGHTVKRVQESDVENVLISDD
KVEDLRMRAPVVTVMGHVDHGKTSLLDALKSTDIAASETGGITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAKV
TDIVIIVVAADDGIKTQTVESINHAKAAGVPIIVAINKIDKPDIDIERVKNELYVHEIIGEEAGGDVMVIPISALKKINL
EKLEEAILLVAEMKDLKASPFGPASGVVIESKIEKGRGTLTTILVQRGTLRNGDIIIAGSSYGKVKKMTNDKGLEIVEAT
PSVPVEIQGLNEVPFAGDKFNVVQNEKQAKDIAEYRMRLAKEKKISIAPRSSLEDLFLKASGNSKIKELPLIIKGDVQGS
VEAILGSLLKLPSDAIKLRILHSGVGPITESDVSLAHASSAIIVGFNVRAGANALTAAEKEKVDIRYYSIIYNLIDDVKA
IMSGMLDPIVREQYIGSVEIRQIFNITKVGKIAGSYVTKGIIKQGASVRLLRDNVVIHEGKLKTLKRFKDEVKEVREGYE
CGIAFENYEDIREGDTVEVFELVQEQRQL

Sequences:

>Translated_829_residues
MTDNQEIKPKKLTLGNSKLSLNKSFDSLTGAQSFVNAKSKTLVEVRKSSTGSTTTISLNQERNSLDHTAIDANKEEFNRR
LSILKKAAEQSKLNDTSQISTLSKLASINQSANSKIEPLETDKEVEQKQQNNEENKVEVSAKIVQDNEHIPSQISKKKEE
SFVKSPLVGMRTRYGIELEKELDKTADSKVVAPKIKLEEPKKFKKVDLFNMLGDDESGRTRSLASIKRAREKEKRKLASQ
APEKVYREVTIPEVIGVGDLANAMSERVADVIKELMKLGVLANASQTIDTDTAELVATNLGHTVKRVQESDVENVLISDD
KVEDLRMRAPVVTVMGHVDHGKTSLLDALKSTDIAASETGGITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAKV
TDIVIIVVAADDGIKTQTVESINHAKAAGVPIIVAINKIDKPDIDIERVKNELYVHEIIGEEAGGDVMVIPISALKKINL
EKLEEAILLVAEMKDLKASPFGPASGVVIESKIEKGRGTLTTILVQRGTLRNGDIIIAGSSYGKVKKMTNDKGLEIVEAT
PSVPVEIQGLNEVPFAGDKFNVVQNEKQAKDIAEYRMRLAKEKKISIAPRSSLEDLFLKASGNSKIKELPLIIKGDVQGS
VEAILGSLLKLPSDAIKLRILHSGVGPITESDVSLAHASSAIIVGFNVRAGANALTAAEKEKVDIRYYSIIYNLIDDVKA
IMSGMLDPIVREQYIGSVEIRQIFNITKVGKIAGSYVTKGIIKQGASVRLLRDNVVIHEGKLKTLKRFKDEVKEVREGYE
CGIAFENYEDIREGDTVEVFELVQEQRQL
>Mature_828_residues
TDNQEIKPKKLTLGNSKLSLNKSFDSLTGAQSFVNAKSKTLVEVRKSSTGSTTTISLNQERNSLDHTAIDANKEEFNRRL
SILKKAAEQSKLNDTSQISTLSKLASINQSANSKIEPLETDKEVEQKQQNNEENKVEVSAKIVQDNEHIPSQISKKKEES
FVKSPLVGMRTRYGIELEKELDKTADSKVVAPKIKLEEPKKFKKVDLFNMLGDDESGRTRSLASIKRAREKEKRKLASQA
PEKVYREVTIPEVIGVGDLANAMSERVADVIKELMKLGVLANASQTIDTDTAELVATNLGHTVKRVQESDVENVLISDDK
VEDLRMRAPVVTVMGHVDHGKTSLLDALKSTDIAASETGGITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAKVT
DIVIIVVAADDGIKTQTVESINHAKAAGVPIIVAINKIDKPDIDIERVKNELYVHEIIGEEAGGDVMVIPISALKKINLE
KLEEAILLVAEMKDLKASPFGPASGVVIESKIEKGRGTLTTILVQRGTLRNGDIIIAGSSYGKVKKMTNDKGLEIVEATP
SVPVEIQGLNEVPFAGDKFNVVQNEKQAKDIAEYRMRLAKEKKISIAPRSSLEDLFLKASGNSKIKELPLIIKGDVQGSV
EAILGSLLKLPSDAIKLRILHSGVGPITESDVSLAHASSAIIVGFNVRAGANALTAAEKEKVDIRYYSIIYNLIDDVKAI
MSGMLDPIVREQYIGSVEIRQIFNITKVGKIAGSYVTKGIIKQGASVRLLRDNVVIHEGKLKTLKRFKDEVKEVREGYEC
GIAFENYEDIREGDTVEVFELVQEQRQL

Specific function: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 7

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family [H]

Homologues:

Organism=Homo sapiens, GI53729339, Length=543, Percent_Identity=43.2780847145488, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI53729337, Length=543, Percent_Identity=43.2780847145488, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI84043963, Length=456, Percent_Identity=29.3859649122807, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI157426893, Length=244, Percent_Identity=29.9180327868852, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1789559, Length=592, Percent_Identity=53.3783783783784, Blast_Score=606, Evalue=1e-174,
Organism=Escherichia coli, GI2367247, Length=217, Percent_Identity=29.4930875576037, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1788922, Length=236, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994658, Length=542, Percent_Identity=38.0073800738007, Blast_Score=353, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI212656558, Length=549, Percent_Identity=26.5938069216758, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17557151, Length=222, Percent_Identity=31.0810810810811, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556456, Length=246, Percent_Identity=31.3008130081301, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324550, Length=658, Percent_Identity=37.3860182370821, Blast_Score=385, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319282, Length=567, Percent_Identity=25.7495590828924, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323320, Length=234, Percent_Identity=26.0683760683761, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28572034, Length=538, Percent_Identity=44.4237918215613, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI160714833, Length=75, Percent_Identity=69.3333333333333, Blast_Score=113, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24656849, Length=132, Percent_Identity=46.2121212121212, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19922690, Length=232, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006847
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000178
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2; PF04760 IF2_N [H]

EC number: NA

Molecular weight: Translated: 90894; Mature: 90763

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS01176 IF2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNQEIKPKKLTLGNSKLSLNKSFDSLTGAQSFVNAKSKTLVEVRKSSTGSTTTISLNQ
CCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECC
ERNSLDHTAIDANKEEFNRRLSILKKAAEQSKLNDTSQISTLSKLASINQSANSKIEPLE
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
TDKEVEQKQQNNEENKVEVSAKIVQDNEHIPSQISKKKEESFVKSPLVGMRTRYGIELEK
CHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
ELDKTADSKVVAPKIKLEEPKKFKKVDLFNMLGDDESGRTRSLASIKRAREKEKRKLASQ
HHCCCCCCCEECCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
APEKVYREVTIPEVIGVGDLANAMSERVADVIKELMKLGVLANASQTIDTDTAELVATNL
CHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
GHTVKRVQESDVENVLISDDKVEDLRMRAPVVTVMGHVDHGKTSLLDALKSTDIAASETG
HHHHHHHHHHCCCEEEECCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
GITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAKVTDIVIIVVAADDGIKTQTVE
CHHHHCCCEEEEEECCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHH
SINHAKAAGVPIIVAINKIDKPDIDIERVKNELYVHEIIGEEAGGDVMVIPISALKKINL
HHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCH
EKLEEAILLVAEMKDLKASPFGPASGVVIESKIEKGRGTLTTILVQRGTLRNGDIIIAGS
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHCCCCCEEEEEEECCCCCCCCEEEECC
SYGKVKKMTNDKGLEIVEATPSVPVEIQGLNEVPFAGDKFNVVQNEKQAKDIAEYRMRLA
CCCCHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
KEKKISIAPRSSLEDLFLKASGNSKIKELPLIIKGDVQGSVEAILGSLLKLPSDAIKLRI
HCCCEEECCCCCCCHHEEECCCCCCHHHCCEEEECCCCCHHHHHHHHHHHCCCHHEEEEE
LHSGVGPITESDVSLAHASSAIIVGFNVRAGANALTAAEKEKVDIRYYSIIYNLIDDVKA
EECCCCCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHCHHHCCHHHHHHHHHHHHHHHHH
IMSGMLDPIVREQYIGSVEIRQIFNITKVGKIAGSYVTKGIIKQGASVRLLRDNVVIHEG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECC
KLKTLKRFKDEVKEVREGYECGIAFENYEDIREGDTVEVFELVQEQRQL
HHHHHHHHHHHHHHHHCCHHCCEEECCHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDNQEIKPKKLTLGNSKLSLNKSFDSLTGAQSFVNAKSKTLVEVRKSSTGSTTTISLNQ
CCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECC
ERNSLDHTAIDANKEEFNRRLSILKKAAEQSKLNDTSQISTLSKLASINQSANSKIEPLE
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
TDKEVEQKQQNNEENKVEVSAKIVQDNEHIPSQISKKKEESFVKSPLVGMRTRYGIELEK
CHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
ELDKTADSKVVAPKIKLEEPKKFKKVDLFNMLGDDESGRTRSLASIKRAREKEKRKLASQ
HHCCCCCCCEECCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
APEKVYREVTIPEVIGVGDLANAMSERVADVIKELMKLGVLANASQTIDTDTAELVATNL
CHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
GHTVKRVQESDVENVLISDDKVEDLRMRAPVVTVMGHVDHGKTSLLDALKSTDIAASETG
HHHHHHHHHHCCCEEEECCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
GITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAKVTDIVIIVVAADDGIKTQTVE
CHHHHCCCEEEEEECCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHH
SINHAKAAGVPIIVAINKIDKPDIDIERVKNELYVHEIIGEEAGGDVMVIPISALKKINL
HHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCH
EKLEEAILLVAEMKDLKASPFGPASGVVIESKIEKGRGTLTTILVQRGTLRNGDIIIAGS
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHCCCCCEEEEEEECCCCCCCCEEEECC
SYGKVKKMTNDKGLEIVEATPSVPVEIQGLNEVPFAGDKFNVVQNEKQAKDIAEYRMRLA
CCCCHHHCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHH
KEKKISIAPRSSLEDLFLKASGNSKIKELPLIIKGDVQGSVEAILGSLLKLPSDAIKLRI
HCCCEEECCCCCCCHHEEECCCCCCHHHCCEEEECCCCCHHHHHHHHHHHCCCHHEEEEE
LHSGVGPITESDVSLAHASSAIIVGFNVRAGANALTAAEKEKVDIRYYSIIYNLIDDVKA
EECCCCCCCCCCCHHHCCCCEEEEEEECCCCCCHHHHCHHHCCHHHHHHHHHHHHHHHHH
IMSGMLDPIVREQYIGSVEIRQIFNITKVGKIAGSYVTKGIIKQGASVRLLRDNVVIHEG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECC
KLKTLKRFKDEVKEVREGYECGIAFENYEDIREGDTVEVFELVQEQRQL
HHHHHHHHHHHHHHHHCCHHCCEEECCHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA