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The map label for this gene is ampH [H]

Identifier: 157825474

GI number: 157825474

Start: 351424

End: 352617

Strand: Direct

Name: ampH [H]

Synonym: A1C_01875

Alternate gene names: 157825474

Gene position: 351424-352617 (Clockwise)

Preceding gene: 157825473

Following gene: 157825475

Centisome position: 28.55

GC content: 29.56

Gene sequence:

>1194_bases
GTGGAAGTTATGATTCGTAGATATTTTGTATTGCTGCTTTTTTTAATTACTAATAGTATTGGTTGTTTTGCAGATATACA
GCAAAGAATCAATGCAGCAGAAAAAGAATATATGAGTAATAGATTTTTAAATGCTGTTTTTATGTTTGCCGATGATTATA
AACCTTTATTCACCGGTGCTAAAGGAATTTTTGCTTTAAACGGTGAGCAATTAAAAGCAAATGAAATGATGCCCATTGCT
TCTGCTACAAAACCTTTTACAGCAGCAGGAATTTTAAAATTACAAGAACAGGAATTATTAAATATTAATGATAAAATCTA
TAAATATCTTGATCCGGACATGTGGGGTGGAAAAGTACCAGATTGGGCATATAAAATATCTATTCATAATTTATTAACGC
ATAGTAGCGGTATTGCTGAATATTTTAGTTTTGTTAAACTTGATTTAAATATGCCTCAGAAAGAGATTCACAAGAAAATA
TTACAATTTGTTTCTTCTAAACCTTTAGAAATATCTATAGGGACAAAATTTAAATATAGTAATACTAATTTTGTTATACT
CGGTATGATTATCGAAAAAGTAGCTAAAAAAGATTTAGGTGACTTTTTTTATGATGAATTTTTTAAACCTCTTGGCATGA
AATCTACTAGTTTTGCTTCATATAGTGATGCTGCTAGAATTCAGAAAAATGTTGTTAGTGCTAATTATCCGGTAAGATAT
TTTTTAACGCCTAATAATAGTAATAAACCTATATTTACTCCTGTAATTGCTGAGTTTTTAGCAGTTCCTTGTGGAGATGG
AGGGATCATATCAACCCCAAACGATCTAGTTAAATGGTATAGGGCATTAAATGAGGGGACAATTCTTTCTAAGAAGTCGT
ATAAACTTATGACTACTAAATATTTTTTAGCAAAAGATACAGAAGGGCGTAAGTCTTATATGGGTTACGGTATTTTTCTT
ACGGATCTTGATTCTAAGCATTTAATGATTCATTATACGGGAAAAGCCCTTGGCATACAAAGTGAAGCAGGATATGTTTT
GCCTGATAATCTTTATTTTGCTATACTTAGTAATACTATGATTAAAATTCCTGAAGAAGAAAAAGATAAAATTGACATGA
AAAATCCTTTAAATCAACTTGGAATAATTTATTTCAGAGATGCAATAATAGAGGCAGCTATAAAAAATGATTAA

Upstream 100 bases:

>100_bases
CGTATGCTTGTGTACGCTGCGGTTCGAAGTGCAGTGTCTCTGTCACATCCCTATTTGTTAGCAAACGTTTGTAAGACGTC
TACTGATCAGTTTATGGAGT

Downstream 100 bases:

>100_bases
ATAAAAACATTAAATGAAGATAGTGACTTGGAATATTAATTCATTGCGTCTACGGATTGACTTATTAAGAAAATTAGTAT
ATGAACATCAGCCGGATATT

Product: penicillin-binding protein 4*

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MEVMIRRYFVLLLFLITNSIGCFADIQQRINAAEKEYMSNRFLNAVFMFADDYKPLFTGAKGIFALNGEQLKANEMMPIA
SATKPFTAAGILKLQEQELLNINDKIYKYLDPDMWGGKVPDWAYKISIHNLLTHSSGIAEYFSFVKLDLNMPQKEIHKKI
LQFVSSKPLEISIGTKFKYSNTNFVILGMIIEKVAKKDLGDFFYDEFFKPLGMKSTSFASYSDAARIQKNVVSANYPVRY
FLTPNNSNKPIFTPVIAEFLAVPCGDGGIISTPNDLVKWYRALNEGTILSKKSYKLMTTKYFLAKDTEGRKSYMGYGIFL
TDLDSKHLMIHYTGKALGIQSEAGYVLPDNLYFAILSNTMIKIPEEEKDKIDMKNPLNQLGIIYFRDAIIEAAIKND

Sequences:

>Translated_397_residues
MEVMIRRYFVLLLFLITNSIGCFADIQQRINAAEKEYMSNRFLNAVFMFADDYKPLFTGAKGIFALNGEQLKANEMMPIA
SATKPFTAAGILKLQEQELLNINDKIYKYLDPDMWGGKVPDWAYKISIHNLLTHSSGIAEYFSFVKLDLNMPQKEIHKKI
LQFVSSKPLEISIGTKFKYSNTNFVILGMIIEKVAKKDLGDFFYDEFFKPLGMKSTSFASYSDAARIQKNVVSANYPVRY
FLTPNNSNKPIFTPVIAEFLAVPCGDGGIISTPNDLVKWYRALNEGTILSKKSYKLMTTKYFLAKDTEGRKSYMGYGIFL
TDLDSKHLMIHYTGKALGIQSEAGYVLPDNLYFAILSNTMIKIPEEEKDKIDMKNPLNQLGIIYFRDAIIEAAIKND
>Mature_397_residues
MEVMIRRYFVLLLFLITNSIGCFADIQQRINAAEKEYMSNRFLNAVFMFADDYKPLFTGAKGIFALNGEQLKANEMMPIA
SATKPFTAAGILKLQEQELLNINDKIYKYLDPDMWGGKVPDWAYKISIHNLLTHSSGIAEYFSFVKLDLNMPQKEIHKKI
LQFVSSKPLEISIGTKFKYSNTNFVILGMIIEKVAKKDLGDFFYDEFFKPLGMKSTSFASYSDAARIQKNVVSANYPVRY
FLTPNNSNKPIFTPVIAEFLAVPCGDGGIISTPNDLVKWYRALNEGTILSKKSYKLMTTKYFLAKDTEGRKSYMGYGIFL
TDLDSKHLMIHYTGKALGIQSEAGYVLPDNLYFAILSNTMIKIPEEEKDKIDMKNPLNQLGIIYFRDAIIEAAIKND

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=313, Percent_Identity=24.9201277955272, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI115533026, Length=327, Percent_Identity=25.6880733944954, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 45122; Mature: 45122

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVMIRRYFVLLLFLITNSIGCFADIQQRINAAEKEYMSNRFLNAVFMFADDYKPLFTGA
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCC
KGIFALNGEQLKANEMMPIASATKPFTAAGILKLQEQELLNINDKIYKYLDPDMWGGKVP
CEEEEECCCEEECCCCCCCCCCCCCCHHHHHHEECHHHHHCCCHHHHHHCCCCCCCCCCC
DWAYKISIHNLLTHSSGIAEYFSFVKLDLNMPQKEIHKKILQFVSSKPLEISIGTKFKYS
CEEEEEEHHHHHHCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCEEEEC
NTNFVILGMIIEKVAKKDLGDFFYDEFFKPLGMKSTSFASYSDAARIQKNVVSANYPVRY
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
FLTPNNSNKPIFTPVIAEFLAVPCGDGGIISTPNDLVKWYRALNEGTILSKKSYKLMTTK
EECCCCCCCCEEHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHCCCCEEECCCCEEEEEE
YFLAKDTEGRKSYMGYGIFLTDLDSKHLMIHYTGKALGIQSEAGYVLPDNLYFAILSNTM
EEEEECCCCCHHHCEEEEEEEECCCCEEEEEECCCEEEEECCCCEECCCCEEEEEECCCE
IKIPEEEKDKIDMKNPLNQLGIIYFRDAIIEAAIKND
EECCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEVMIRRYFVLLLFLITNSIGCFADIQQRINAAEKEYMSNRFLNAVFMFADDYKPLFTGA
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCC
KGIFALNGEQLKANEMMPIASATKPFTAAGILKLQEQELLNINDKIYKYLDPDMWGGKVP
CEEEEECCCEEECCCCCCCCCCCCCCHHHHHHEECHHHHHCCCHHHHHHCCCCCCCCCCC
DWAYKISIHNLLTHSSGIAEYFSFVKLDLNMPQKEIHKKILQFVSSKPLEISIGTKFKYS
CEEEEEEHHHHHHCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCEEEEC
NTNFVILGMIIEKVAKKDLGDFFYDEFFKPLGMKSTSFASYSDAARIQKNVVSANYPVRY
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
FLTPNNSNKPIFTPVIAEFLAVPCGDGGIISTPNDLVKWYRALNEGTILSKKSYKLMTTK
EECCCCCCCCEEHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHCCCCEEECCCCEEEEEE
YFLAKDTEGRKSYMGYGIFLTDLDSKHLMIHYTGKALGIQSEAGYVLPDNLYFAILSNTM
EEEEECCCCCHHHCEEEEEEEECCCCEEEEEECCCEEEEECCCCEECCCCEEEEEECCCE
IKIPEEEKDKIDMKNPLNQLGIIYFRDAIIEAAIKND
EECCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]