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The map label for this gene is rpoB [H]

Identifier: 157825320

GI number: 157825320

Start: 185804

End: 189925

Strand: Direct

Name: rpoB [H]

Synonym: A1C_01010

Alternate gene names: 157825320

Gene position: 185804-189925 (Clockwise)

Preceding gene: 157825319

Following gene: 157825321

Centisome position: 15.09

GC content: 34.59

Gene sequence:

>4122_bases
ATGGTTTCATTAAGGGATAATATAGAAGCACAACCCTTGTCACATAATAGAAGAATAAGAAAAAATTTCGGTCACATAAA
TTTAGTAGCAGATATACCAAATTTGATTGAAATTCAAAAAAATTCATATGAAAAAAACTTTCTACAGTTAAATATTAAAG
ATTCTGAAAGAAAAAATAAAGGTTTACAATCTATATTAAACTCAATTTTTCCTATTTCAGATTCCTCCAATATTGCTAAT
TTAGAATTTGTAAAATATGAATTCGATACTCCAAAATATGATGTAGAAGAATGTAGTCAAAGAAGTTTAAGTTATGCTGC
TCCTCTTAAAGTTACTTTAAGGTTAAGTATTTGGGATATAGATGAGGATACCGGTACTAGAGAAATTAAAGGGATTAAAG
AGCAAGAAGTATATATGGGTGATATCCCATTAATGACTAAAAACGGTACTTTTATCATTAATGGTACAGAAAGGGTAGTT
GTGTCGCAAATGCATCGCTCACCTGGTGTATTCTTTTATCATGATGAAGGAAAAGTCCACTCTTCCGGCAAGCTTTTATA
TTCTGCTCGTGTTATTCCATATAGAGGATCTTGGCTTGATTTAGAATTCGATGCTAAAGATGTTCTTTATTTCAGGATTG
ATAGAAAAAGAAAGCTTTATGCTACTACTTTGCTTAGAGCTATAGGTATGAGTACTGAAGAAATTATAAAATTTTATTAT
AATTCAGTAACTTATAAGCTTGTTAAAAAGAAAGGTTGGGCGGTTAAATTTATACCTAAGCATATTACTGCTCATCGTTT
AACCAGTGATTTAGTAGATGCAGATACTGGAAATGTTCTACTGAAGGCAGGACAAAAAATTACCCCGCGTTTGGCTCAAA
AATATTGTGCTGAAGGTATTAATAATATTTTAGTAGCTCATGAAACTTTAATCGGCAAATATCTATCCGAAGATTTAAGA
GATCCTGCAAGCGATGAAGTATTAGCAAAAATCGGTGAAATAATAACTAGCGATATGCTAAATGTTATTAATGATCTTAA
AATTAAAAATGTTAACGTATTAGTAATCAACCCTCAGTCCGGTCCATATATAAGAAATACCTTATTTGCTGATAAGAATC
AGGACCGTGAGGCAGCATTATGTGACATTTTTAGAGTTTTAAGACCAGGTGAACCTACTAATATAGAAGCGGCTGAAAGC
CTGTTTTATAATTTATTCTTTGATTCTGAAAGATATGATCTTTCAGAAGTCGGACGAATAAAAATGAATTCTAGGTTAGG
GCTTAGTATTTCTGAAGAAGTTACGGTTTTAACAATTGATGATATTAAAAATATCGTAAGAGTTTTGGTAGAGCTTAAAG
ATGGTAAAGGTATAATAGACGATATTGATCATTTAGGTAATAGAAGGGTTAGATCGGTAGGTGAATTGATAGAAAATCAA
TTTAGAATAGGTTTAGTCCGAATGGAAAAATCTGTAATTGAAAGGATGTCGGCAGGTGATGTTGATACCGTAATGCCTCA
TGATTTAGTAAATTCCAAGATTTTAGTTTCAGTCGTAAAAGAATTTTTTAGTACCTCCCAATTATCACAATTTATGGATC
AAACAAATCCATTATCGGAAATAACACATAAAAGAAGGCTGTCGGCACTCGGTCCTGGAGGTCTTAGTCGAGATCGAGCA
GGTTTTGAGGTGCGTGATGTACATCCTACTCATTACGGGCGTATTTGTCCTATTGAAACACCTGAAGGTCAGAATATCGG
GTTAATTAACTCTATGGCTACTTACGCTAGGATAAATAAACACGGTTTTATAGAGAGTCCGTATAGAAAAGTTAAAGATG
GGCGTGTAATCGATGAAGTGATATATCTTTCTGCTATTGAAGAAGGTAAATACAAAATCGGACAGGCAAATTCTAAAGTT
GATCGAGATGGAAAGCTGCAAGGAGAGTTTATTAATTGTCGTGTTGAAGGCGGTAATTTTGTAATGGTAGAACCGCATGA
GGTAGATTTTATTGATGTGACTCCTATGCAGGTAGTATCGGTTGCGGCTTCTCTTATACCGTTCTTAGAAAACGATGATG
CTAACCGTGCTTTGATGGGGTCAAACATGCAAAGACAAGCTGTTCCTTTAATTAAAACGGATGCACCTTTTGTAGGTACC
GGAGTTGAAGGGGTAGTAGCTAAAGATTCTGGAGCGTCTGTGCTTGCATTACATGACGGTATTGTTGAGCAGGTAGATTC
AAATAGAATCGTGATTAGAACTCTAGAACAAAAAATTGATGGTTCTCCTTCTGTTTATATTTATAATTTATTAAAATTCC
AAAAGTCCAATCATAATACTTGTATAAATCAAAAGCCTTTAGTTCAGGTTGGTCATTATGTTAAGAAAAACGATATTATA
GCTGACGGTCCTAGTACGGATAACGGTGAAATTGCTTTAGGTAGAAACGTGCTTGTGGCTTTCTTACCTTGGAACGGTTA
CAATTTTGAAGATTCAATTTTAATATCTGAACGTATAGTAAAAGAGGATATATTTACATCGATTCATATTGAAGAATTTG
AAGTAATAGCTAGAGATACACGCCTTGGTCCTGAAGAAATTACCCGTGATATACCGAATGTAAGTGAAGAAGCGTTGCGT
CATCTTGATGAAGTCGGAATAATTTATGTAGGTGCAGAAGTAAAAGCCGGTGATATTTTAGTCGGAAAAGTAACACCGAA
AAGTGAATCGCCTATTACTCCTGAAGAGAAGCTACTACGTGCTATTTTTGGGGAGAAAGCTTTTGATGTAAAAGATTCAT
CGCTGCATGTACCTTCTGGAGTGAGCGGAACTGTAGTAGAAGTAAGGGTCTTTTCTCGTAGGGGTGTAGAAAAAGACCAG
CGAGCTATTGCTATTGAAAAACAACAAATTGAAAAATTAGCAAAAGACAGAGATGATGAATTAGAAATTATTGAGCATTT
TGTGTTTAGTTTGCTTGAAAAGCTTTTAGTAGGGCAGGTGATTATTAACGGTCTTAAGCAAGTAAAAGCAGGACAAACTA
TTACTACTGAAATGCTAAAAGGTTTATCTAAAGGGCAGTTTTGGCAGCTTACTGTGGAAGATGCAAATGTAATGAATGAA
ATAGAGCAGATAAAGATTCATTATGATGAGAAAAAAGATGCCCTCAATAAAAGATTTGCTACTAAGGTAGAGAAATTGCA
AAGCGGTGATGATTTACCTCAGGGAGCTTTAAAAGTAGTAAAAGTATTTATCGCAACTAAGCATAAATTACAGCCTGGTG
ATAAGATGGCAGGAAGGCACGGAAATAAAGGTGTTGTTTCACGTATCGTACCTGAAGAAGATATGCCATTTTTAGAAGAT
GGAACTGTGGTAGATATTGTTCTAAATCCTCTAGGTCTTCCGTCACGTATGAATATAGGACAGATTTTAGAAACGCATCT
TGGGTGGGCATCAATAAATTTAGCACAAAAAATATCTACATTAGTAAAGGAATATAAAAATAAAAATATAGGTATTGAGA
AAATTAAGAAATTCTTACTTGAGCTATACGGAGAGAATATTAATTATATACTTGAAAGATCTGAAGAAGAGATTATCTCC
TTCTGTAATAAAGTAGGTAAAGGCGTATATTTTGCAACTCCTGTATTTGACGGAGCAAAAGTTCAGGACGTTAAAGATAT
GTTAAAACTTGCCGGTCAAGATCCTTCAGGACAAGTAAAATTAATTGATGGTAGAACCGGTGAATATTTTGACCGTCTAG
TGACTGTTGGACAGAAATATTTGCTGAAGCTGCATCACTTAGTCGATAATAAAATTCACTCTCGTTCTATAGGACCTTAT
AGCTTAGTAACGCAGCAACCGCTTGGAGGTAAGTCTCATTTCGGTGGACAGCGTTTCGGAGAAATGGAATGCTGGGCATT
ACAAGCTTACGGTGCGGCCTATACGTTACAGGAAATGTTAACTGTTAAGTCAGATGACGTAAACGGTAGGATTAAAACTT
ATGATTCTATAGTACGTGGTGAAAATAATTTTGAATCAGGTATTCCTGAATCATTTAATGTGATGATAAAAGAATTTAGA
TCTTTATGTCTTAACGTAAAGCTTGAAGTAACTTCGAGTTAA

Upstream 100 bases:

>100_bases
TTTACAGCTAAAAAGAGTCATAATTATAATTGTTCTATTAAAAATGCATAGGACCTAATCACTTCAATACGGGCAGTAAT
TTTATCAGTCGGGAGATTAT

Downstream 100 bases:

>100_bases
ATGTGTACTCGGTGAATTTCAAAAATTGGCTACGTCGTCTAGCAAATTTTGTGGTGCTAACGTATTAAGTATACGCTCCG
CTCCTCGTCTTACGGACTCC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1373; Mature: 1373

Protein sequence:

>1373_residues
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN
LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV
VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY
NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGINNILVAHETLIGKYLSEDLR
DPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAES
LFYNLFFDSERYDLSEVGRIKMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA
GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKV
DRDGKLQGEFINCRVEGGNFVMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNTCINQKPLVQVGHYVKKNDII
ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR
HLDEVGIIYVGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLKGLSKGQFWQLTVEDANVMNE
IEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLED
GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS
FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY
SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR
SLCLNVKLEVTSS

Sequences:

>Translated_1373_residues
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN
LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV
VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY
NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGINNILVAHETLIGKYLSEDLR
DPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAES
LFYNLFFDSERYDLSEVGRIKMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA
GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKV
DRDGKLQGEFINCRVEGGNFVMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNTCINQKPLVQVGHYVKKNDII
ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR
HLDEVGIIYVGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLKGLSKGQFWQLTVEDANVMNE
IEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLED
GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS
FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY
SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR
SLCLNVKLEVTSS
>Mature_1373_residues
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNKGLQSILNSIFPISDSSNIAN
LEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDIDEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVV
VSQMHRSPGVFFYHDEGKVHSSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY
NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGINNILVAHETLIGKYLSEDLR
DPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQSGPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAES
LFYNLFFDSERYDLSEVGRIKMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSEITHKRRLSALGPGGLSRDRA
GFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINKHGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKV
DRDGKLQGEFINCRVEGGNFVMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNTCINQKPLVQVGHYVKKNDII
ADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIVKEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALR
HLDEVGIIYVGAEVKAGDILVGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLKGLSKGQFWQLTVEDANVMNE
IEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVVKVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLED
GTVVDIVLNPLGLPSRMNIGQILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS
FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKYLLKLHHLVDNKIHSRSIGPY
SLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEMLTVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFR
SLCLNVKLEVTSS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908503, Length=303, Percent_Identity=29.3729372937294, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI238908505, Length=303, Percent_Identity=29.3729372937294, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI33469941, Length=291, Percent_Identity=29.8969072164948, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI212286172, Length=291, Percent_Identity=29.8969072164948, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI4505941, Length=315, Percent_Identity=29.8412698412698, Blast_Score=120, Evalue=7e-27,
Organism=Escherichia coli, GI1790419, Length=1363, Percent_Identity=54.512105649303, Blast_Score=1490, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=248, Percent_Identity=31.8548387096774, Blast_Score=123, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17552304, Length=248, Percent_Identity=32.258064516129, Blast_Score=111, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324781, Length=305, Percent_Identity=30.1639344262295, Blast_Score=126, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325267, Length=249, Percent_Identity=31.3253012048193, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324725, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17647877, Length=247, Percent_Identity=31.1740890688259, Blast_Score=118, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136444, Length=310, Percent_Identity=27.0967741935484, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17136446, Length=280, Percent_Identity=28.9285714285714, Blast_Score=104, Evalue=5e-22,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 154166; Mature: 154166

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNK
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEECCCHHHHH
GLQSILNSIFPISDSSNIANLEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDI
HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEEC
DEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVH
CCCCCCHHHCCCCHHCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCEEEECCCCCEE
SSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY
CCCCEEEEEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGI
HHHHEEEHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHH
NNILVAHETLIGKYLSEDLRDPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECEEEEEECCCC
GPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAESLFYNLFFDSERYDLSEVGRI
CCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCHHHCCEE
KMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
EECCCCCCEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHH
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
HGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKVDRDGKLQGEFINCRVEGGNF
CCCCCCHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCE
VMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
EEECCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHCCCEEECCCCEECC
GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNT
CCCEEEECCCCCEEEEECCHHHHHCCCCEEEEEEHHHHHCCCCCEEEEEEHHHHCCCCCC
CINQKPLVQVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIV
CCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHH
KEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYVGAEVKAGDIL
HHHHHHHEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCEEEEECEECCCCEE
VGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHH
RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GLSKGQFWQLTVEDANVMNEIEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVV
CCCCCCEEEEEECCHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIG
HHHHHHHCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
QILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHH
FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKY
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEML
HHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHH
TVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTSS
HHCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECC
>Mature Secondary Structure
MVSLRDNIEAQPLSHNRRIRKNFGHINLVADIPNLIEIQKNSYEKNFLQLNIKDSERKNK
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHCCCCCCCEEEEEECCCHHHHH
GLQSILNSIFPISDSSNIANLEFVKYEFDTPKYDVEECSQRSLSYAAPLKVTLRLSIWDI
HHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEEEEEEC
DEDTGTREIKGIKEQEVYMGDIPLMTKNGTFIINGTERVVVSQMHRSPGVFFYHDEGKVH
CCCCCCHHHCCCCHHCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCEEEECCCCCEE
SSGKLLYSARVIPYRGSWLDLEFDAKDVLYFRIDRKRKLYATTLLRAIGMSTEEIIKFYY
CCCCEEEEEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
NSVTYKLVKKKGWAVKFIPKHITAHRLTSDLVDADTGNVLLKAGQKITPRLAQKYCAEGI
HHHHEEEHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHH
NNILVAHETLIGKYLSEDLRDPASDEVLAKIGEIITSDMLNVINDLKIKNVNVLVINPQS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECEEEEEECCCC
GPYIRNTLFADKNQDREAALCDIFRVLRPGEPTNIEAAESLFYNLFFDSERYDLSEVGRI
CCCCHHEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCHHHCCEE
KMNSRLGLSISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGNRRVRSVGELIENQ
EECCCCCCEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHH
FRIGLVRMEKSVIERMSAGDVDTVMPHDLVNSKILVSVVKEFFSTSQLSQFMDQTNPLSE
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ITHKRRLSALGPGGLSRDRAGFEVRDVHPTHYGRICPIETPEGQNIGLINSMATYARINK
HHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
HGFIESPYRKVKDGRVIDEVIYLSAIEEGKYKIGQANSKVDRDGKLQGEFINCRVEGGNF
CCCCCCHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCEEEEEEEECCCE
VMVEPHEVDFIDVTPMQVVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPFVGT
EEECCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHCCCEEECCCCEECC
GVEGVVAKDSGASVLALHDGIVEQVDSNRIVIRTLEQKIDGSPSVYIYNLLKFQKSNHNT
CCCEEEECCCCCEEEEECCHHHHHCCCCEEEEEEHHHHHCCCCCEEEEEEHHHHCCCCCC
CINQKPLVQVGHYVKKNDIIADGPSTDNGEIALGRNVLVAFLPWNGYNFEDSILISERIV
CCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHH
KEDIFTSIHIEEFEVIARDTRLGPEEITRDIPNVSEEALRHLDEVGIIYVGAEVKAGDIL
HHHHHHHEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCEEEEECEECCCCEE
VGKVTPKSESPITPEEKLLRAIFGEKAFDVKDSSLHVPSGVSGTVVEVRVFSRRGVEKDQ
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHH
RAIAIEKQQIEKLAKDRDDELEIIEHFVFSLLEKLLVGQVIINGLKQVKAGQTITTEMLK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
GLSKGQFWQLTVEDANVMNEIEQIKIHYDEKKDALNKRFATKVEKLQSGDDLPQGALKVV
CCCCCCEEEEEECCHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KVFIATKHKLQPGDKMAGRHGNKGVVSRIVPEEDMPFLEDGTVVDIVLNPLGLPSRMNIG
HHHHHHHCCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHH
QILETHLGWASINLAQKISTLVKEYKNKNIGIEKIKKFLLELYGENINYILERSEEEIIS
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHH
FCNKVGKGVYFATPVFDGAKVQDVKDMLKLAGQDPSGQVKLIDGRTGEYFDRLVTVGQKY
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHH
LLKLHHLVDNKIHSRSIGPYSLVTQQPLGGKSHFGGQRFGEMECWALQAYGAAYTLQEML
HHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHH
TVKSDDVNGRIKTYDSIVRGENNFESGIPESFNVMIKEFRSLCLNVKLEVTSS
HHCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9555894; 9823893; 10508014 [H]