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The map label for this gene is mnmG [H]

Identifier: 157825212

GI number: 157825212

Start: 72550

End: 74418

Strand: Direct

Name: mnmG [H]

Synonym: A1C_00455

Alternate gene names: 157825212

Gene position: 72550-74418 (Clockwise)

Preceding gene: 157825211

Following gene: 157825213

Centisome position: 5.89

GC content: 32.32

Gene sequence:

>1869_bases
ATGCTAAAATATGACGTAATAGTTATAGGTGGCGGACATGCAGGCGTGGAAGCAGCAGCAGCTTCTGCACGTCTTGGAGT
TTCTACTCTCTTAATTACGTTAAAACCGGACAATTTAGGCGAAATGTCTTGCAATCCAGCAATTGGTGGCATTGCAAAGG
GTACATTAGTTAAAGAAATCGATGCCCTTGATGGGTTAATGGGTTATGTTATAGATCAAGCAGGTATACATTATAAAATG
CTGAATGAGACTAGAGGACCGGCAGTTTGGGGACCTAGAGCTCAAGCTGATCGAAAGCTTTATAAAAAAGCGATGTATCA
AATATTAACAAATTACCCTAATCTGGATATACTATATGGGAAAGTAGAAGATATAGAAATTAAATCTTCTAAAGTTGCAG
CGATTGTTTTAAATAATGATAGCAAAATTCCTTGTCAAAAAATTATATTAACTACGGGTACTTTTCTATCAGGTCTTATT
CATATTGGAAAAAAAAAAATTCCTGCCGGTAGAGTAGATGAAGAGCCTTCGTATGGATTATCAAAGACATTAAAAAAAGT
AGGATTTAAAATTGCCCGTTTAAAAACAGGTACACCACCAAGAATTGACGGGCGTACTATTGATTATAGTAAAACAGCTT
TACAGCCTGGAGATAAAGCTCCTCGTCCTTTTTCTGAATTAACAAATGTTGTCAATGTTCCTCAGATAAATTGTTTTATT
ACAAAAACAACCTCAGAAACTCATGATATTATACGTGAGAACCTTAATAAATCCGCAATGTATTCGGGGCAGATAGAAGG
AATAGGACCGCGATATTGTCCTTCTATTGAAGATAAAATAGTCAGATTTAGTACAAAATCAGAACATCGTATATTTTTAG
AACCTGAGGGGTTAGATGATTATACGATTTATCCAAATGGTATTTCTACTTCTTTGCCTGAAGATGTACAACATAAATTA
ATCAAAACAATACCAGGATTAGAAAATGTAAAGGTTTTACGTCTAGGTTATGCTATAGAATATGATTATGTTGATCCACG
TGAAATAAGTGTTACGCTAGAGACAAAAAAAATAGCTGGATTGTATTTTGCTGGGCAAATTAACGGTACTACAGGATATG
AAGAGGCCGCAGGGCAAGGTATAATAGCCGGTATAAATGCTGCTTTAGCAGTAAAAGATCAAGCACAATTTATATTAACA
AGAGCAAACAGTTATATTGGAGTAATGATTGATGATTTAACAACATTTGGTACTATAGAACCTTATCGTATGTTTACTTC
TCGTTCAGAATATAGATTATCTTTAAGAGCAGATAATGCTGATTTACGTTTAACGGAATTAGGGATCAACATTGGCGTTA
TATCAGAAAAACGTAAAAAAATATTTACAAAAAAATATGAAGATATAGAAAAAACAAAATCATTATTAAATACCTTATCT
TTCACTACTAGTAAACTTGCTAAAATGGACATACAAGTTGCACAGGATGGTACATATAAAACAGTATTAGACTTATTTAA
AATACCTAGTTTTAATATTGAACAAGCTATTAAAATTTTTCCTATGCTTAAAGAAATGCAAAATAATAATATTTTGCAAT
TACTCTATATTGAAGCAAAATATGCTTCATATTTAACTAGACAACAAGCAGATATTAATTTATTTCAAAGTGAAGAGGCA
CAGTTAATACCTAAAAATATTGACTATTTTAAAATACCAAGTATATCATTAGAGATACAGGAAAAACTTTCTTCCCATAA
ACCTACTACTATTGGTTTAGCACGTCGAATTCCAGGGATTACACCTGCAGCAATTACGTCTATTATAATTTATTTAAAAA
CTAAATATAGTGATGGAAGTTTCACGTGA

Upstream 100 bases:

>100_bases
ATCAATTGAGGCTAATAGTATTCATGGTTCAGATAGTGAAAACAGTGCGAAAAGAGAAATCGCATTTTTCTTTAACAAAT
CTGAAATTATAGAATAATTA

Downstream 100 bases:

>100_bases
AATAATTGAAAAATTAGAAATTTTTCAAAAGTTAGTTAAAAAATGGAATAAATCAATCAATCTTGTATCGGGTAATACTA
TACATAATTTTTGGCAACGT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A [H]

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MLKYDVIVIGGGHAGVEAAAASARLGVSTLLITLKPDNLGEMSCNPAIGGIAKGTLVKEIDALDGLMGYVIDQAGIHYKM
LNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYGKVEDIEIKSSKVAAIVLNNDSKIPCQKIILTTGTFLSGLI
HIGKKKIPAGRVDEEPSYGLSKTLKKVGFKIARLKTGTPPRIDGRTIDYSKTALQPGDKAPRPFSELTNVVNVPQINCFI
TKTTSETHDIIRENLNKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDDYTIYPNGISTSLPEDVQHKL
IKTIPGLENVKVLRLGYAIEYDYVDPREISVTLETKKIAGLYFAGQINGTTGYEEAAGQGIIAGINAALAVKDQAQFILT
RANSYIGVMIDDLTTFGTIEPYRMFTSRSEYRLSLRADNADLRLTELGINIGVISEKRKKIFTKKYEDIEKTKSLLNTLS
FTTSKLAKMDIQVAQDGTYKTVLDLFKIPSFNIEQAIKIFPMLKEMQNNNILQLLYIEAKYASYLTRQQADINLFQSEEA
QLIPKNIDYFKIPSISLEIQEKLSSHKPTTIGLARRIPGITPAAITSIIIYLKTKYSDGSFT

Sequences:

>Translated_622_residues
MLKYDVIVIGGGHAGVEAAAASARLGVSTLLITLKPDNLGEMSCNPAIGGIAKGTLVKEIDALDGLMGYVIDQAGIHYKM
LNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYGKVEDIEIKSSKVAAIVLNNDSKIPCQKIILTTGTFLSGLI
HIGKKKIPAGRVDEEPSYGLSKTLKKVGFKIARLKTGTPPRIDGRTIDYSKTALQPGDKAPRPFSELTNVVNVPQINCFI
TKTTSETHDIIRENLNKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDDYTIYPNGISTSLPEDVQHKL
IKTIPGLENVKVLRLGYAIEYDYVDPREISVTLETKKIAGLYFAGQINGTTGYEEAAGQGIIAGINAALAVKDQAQFILT
RANSYIGVMIDDLTTFGTIEPYRMFTSRSEYRLSLRADNADLRLTELGINIGVISEKRKKIFTKKYEDIEKTKSLLNTLS
FTTSKLAKMDIQVAQDGTYKTVLDLFKIPSFNIEQAIKIFPMLKEMQNNNILQLLYIEAKYASYLTRQQADINLFQSEEA
QLIPKNIDYFKIPSISLEIQEKLSSHKPTTIGLARRIPGITPAAITSIIIYLKTKYSDGSFT
>Mature_622_residues
MLKYDVIVIGGGHAGVEAAAASARLGVSTLLITLKPDNLGEMSCNPAIGGIAKGTLVKEIDALDGLMGYVIDQAGIHYKM
LNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYGKVEDIEIKSSKVAAIVLNNDSKIPCQKIILTTGTFLSGLI
HIGKKKIPAGRVDEEPSYGLSKTLKKVGFKIARLKTGTPPRIDGRTIDYSKTALQPGDKAPRPFSELTNVVNVPQINCFI
TKTTSETHDIIRENLNKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDDYTIYPNGISTSLPEDVQHKL
IKTIPGLENVKVLRLGYAIEYDYVDPREISVTLETKKIAGLYFAGQINGTTGYEEAAGQGIIAGINAALAVKDQAQFILT
RANSYIGVMIDDLTTFGTIEPYRMFTSRSEYRLSLRADNADLRLTELGINIGVISEKRKKIFTKKYEDIEKTKSLLNTLS
FTTSKLAKMDIQVAQDGTYKTVLDLFKIPSFNIEQAIKIFPMLKEMQNNNILQLLYIEAKYASYLTRQQADINLFQSEEA
QLIPKNIDYFKIPSISLEIQEKLSSHKPTTIGLARRIPGITPAAITSIIIYLKTKYSDGSFT

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 [H]

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family [H]

Homologues:

Organism=Homo sapiens, GI74024895, Length=631, Percent_Identity=46.5927099841521, Blast_Score=540, Evalue=1e-153,
Organism=Homo sapiens, GI19882217, Length=656, Percent_Identity=44.8170731707317, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI183227703, Length=671, Percent_Identity=43.8152011922504, Blast_Score=522, Evalue=1e-148,
Organism=Escherichia coli, GI2367273, Length=616, Percent_Identity=49.6753246753247, Blast_Score=617, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI17534255, Length=623, Percent_Identity=43.338683788122, Blast_Score=497, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6321202, Length=623, Percent_Identity=47.0304975922953, Blast_Score=580, Evalue=1e-166,
Organism=Drosophila melanogaster, GI24658174, Length=627, Percent_Identity=47.0494417862839, Blast_Score=541, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: NA

Molecular weight: Translated: 68920; Mature: 68920

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS01280 GIDA_1 ; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYDVIVIGGGHAGVEAAAASARLGVSTLLITLKPDNLGEMSCNPAIGGIAKGTLVKEI
CEEEEEEEEECCCCCHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
DALDGLMGYVIDQAGIHYKMLNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYG
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
KVEDIEIKSSKVAAIVLNNDSKIPCQKIILTTGTFLSGLIHIGKKKIPAGRVDEEPSYGL
CEECEEEECCEEEEEEECCCCCCCHHHEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
SKTLKKVGFKIARLKTGTPPRIDGRTIDYSKTALQPGDKAPRPFSELTNVVNVPQINCFI
HHHHHHHCCEEEEEECCCCCCCCCCEECCCHHCCCCCCCCCCCHHHHHHHCCCCEEEEEE
TKTTSETHDIIRENLNKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDD
EECCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHEEEEECCCCCEEEECCCCCCC
YTIYPNGISTSLPEDVQHKLIKTIPGLENVKVLRLGYAIEYDYVDPREISVTLETKKIAG
EEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCEEEEEEEEEEEEE
LYFAGQINGTTGYEEAAGQGIIAGINAALAVKDQAQFILTRANSYIGVMIDDLTTFGTIE
EEEEEEECCCCCCHHHCCCEEEEECCEEEEECCCCEEEEEECCCEEEEEEECCHHCCCCC
PYRMFTSRSEYRLSLRADNADLRLTELGINIGVISEKRKKIFTKKYEDIEKTKSLLNTLS
HHHHHCCCCCEEEEEEECCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
FTTSKLAKMDIQVAQDGTYKTVLDLFKIPSFNIEQAIKIFPMLKEMQNNNILQLLYIEAK
HHHHHHHHEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEH
YASYLTRQQADINLFQSEEAQLIPKNIDYFKIPSISLEIQEKLSSHKPTTIGLARRIPGI
HHHHHHHCCCCCEEEECCCCEECCCCCCEEECCCCCHHHHHHHHCCCCCEEEHHHHCCCC
TPAAITSIIIYLKTKYSDGSFT
CHHHHHEEEEEEEEECCCCCCC
>Mature Secondary Structure
MLKYDVIVIGGGHAGVEAAAASARLGVSTLLITLKPDNLGEMSCNPAIGGIAKGTLVKEI
CEEEEEEEEECCCCCHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
DALDGLMGYVIDQAGIHYKMLNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYG
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
KVEDIEIKSSKVAAIVLNNDSKIPCQKIILTTGTFLSGLIHIGKKKIPAGRVDEEPSYGL
CEECEEEECCEEEEEEECCCCCCCHHHEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
SKTLKKVGFKIARLKTGTPPRIDGRTIDYSKTALQPGDKAPRPFSELTNVVNVPQINCFI
HHHHHHHCCEEEEEECCCCCCCCCCEECCCHHCCCCCCCCCCCHHHHHHHCCCCEEEEEE
TKTTSETHDIIRENLNKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDD
EECCCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHEEEEECCCCCEEEECCCCCCC
YTIYPNGISTSLPEDVQHKLIKTIPGLENVKVLRLGYAIEYDYVDPREISVTLETKKIAG
EEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCEEEEEEEEEEEEE
LYFAGQINGTTGYEEAAGQGIIAGINAALAVKDQAQFILTRANSYIGVMIDDLTTFGTIE
EEEEEEECCCCCCHHHCCCEEEEECCEEEEECCCCEEEEEECCCEEEEEEECCHHCCCCC
PYRMFTSRSEYRLSLRADNADLRLTELGINIGVISEKRKKIFTKKYEDIEKTKSLLNTLS
HHHHHCCCCCEEEEEEECCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
FTTSKLAKMDIQVAQDGTYKTVLDLFKIPSFNIEQAIKIFPMLKEMQNNNILQLLYIEAK
HHHHHHHHEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEH
YASYLTRQQADINLFQSEEAQLIPKNIDYFKIPSISLEIQEKLSSHKPTTIGLARRIPGI
HHHHHHHCCCCCEEEECCCCEECCCCCCEEECCCCCHHHHHHHHCCCCCEEEHHHHCCCC
TPAAITSIIIYLKTKYSDGSFT
CHHHHHEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA