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The map label for this gene is uhpC [H]

Identifier: 157825210

GI number: 157825210

Start: 70807

End: 72096

Strand: Direct

Name: uhpC [H]

Synonym: A1C_00445

Alternate gene names: 157825210

Gene position: 70807-72096 (Clockwise)

Preceding gene: 157825209

Following gene: 157825211

Centisome position: 5.75

GC content: 35.19

Gene sequence:

>1290_bases
ATGACAGATACAAAACCCAAAATTAAAACTCCAAGATCGCCATATGTAAAAAAATATAATAGTTGGCGAGTAAGGATTTT
ATATTCTATTATTATAGGTTATGCGACTTTTTATTTGTGTCGTCAGAATTTTAATATAGCAACTCCTGCTATAAGAGAAT
ATTTTGGGGTTACTAAAACGCAAATTGGTTGGATATTAACTGCTTCATCTATTATGTATGGAGTGAGTAAAGCTTGTAAT
GGGTTTATTAGCGACAAAGTTAATGCTCGGATATTTATGGTTTTGGGTCTTTTAGTTGTCGGAATCATTACTATTCTAAT
AGGTTTTTCATATTCTTTGTGGTTTATAGGAATTTTATGGATATCCAGTAACTGGTTTCAATCGATGGGGTGGCCCCCTG
CAACAAAAATGCTTACTCACTGGTTTGCTTCAAAAGAACTTGGCACTAAATGGGCTATGGGTACAACCTCTAATCAAATA
GGTGGTGCCATTGCTATGATAAGCTGCGGTTATTTAATCGATAAATTTGATTGGAGAGCTGCTTTTTTCGTTCCTGGTGT
AGTCGCTTGTGTAGTATCGCTTTTTTTATATAATAGGCTTCGTAATTCCCCAAAAGAAGTAGGTTTATCTACCGTAGAGG
AATATAAAGAATATCCGCCTGAATCTATAGGAGATTATGAGAAGCTATTAACTCCACAATTACTTAGAATGGTCTTTTGT
AATAGGCTAATATGGTATGTTTGTTTAGCAAATATGTTTGTTTATATAATACGTTCCGGAGTAATTTATTGGGCTCCAAC
ATTTTTAAAAGATTTACGTAATATAAGCCTTGCAAATGCAGGATTACAAATTGGTTTATATGAAATGATAGGTATTCCCG
GGGCGTTGATAGCTGGCTTTTTATCGGATAAATTATTTCAAGGACGTCGCGGTCCTATTGGAGCGATATGTATGGTATTG
CTTAGCTTATTGTTAGTCTTGTTTTGGACAATTCCTATTCAAAGTGAATTATTAAGTATAGTAATTCTATCTTTAATAGG
CTTTTTTGTTGCAGGACCTCAGCTCCTTGTAGGTATAGCAGCTGCTGATTTCAGTACTCGTCAAGCTGTCGGTACGGCTA
ATGGATTATCAGGGTTATTTGGTTATTTAGGAGCCTCTATTGCAGGAATCGGCGTAGGATGGATTAGCGATCATTATGGT
TGGAATGGAGTATTTATATTTTTCAGTATTTCTGCTCTTTTAGGAGGAGGGTTGTTTGCTTTAACATGGAATCGTTCAGC
TAAAAAATAA

Upstream 100 bases:

>100_bases
ATAAAACTGAAAAATAGAATGTGTTAAAATTTAATATTATAACAAAAGTAAGCTGCTCGACTCTGAAACTTGCTTTTTTT
ATAGTCGTGGAGTTTATAAT

Downstream 100 bases:

>100_bases
ATTTAATCATTATATAAAGGTTACAAAATGACAATACAATATACTTTTTCAATGATTAAGCCTGATGCTATCAAGAGGAA
TAAAATAGGACAAGTTAATG

Product: sugar phosphate permease

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTDTKPKIKTPRSPYVKKYNSWRVRILYSIIIGYATFYLCRQNFNIATPAIREYFGVTKTQIGWILTASSIMYGVSKACN
GFISDKVNARIFMVLGLLVVGIITILIGFSYSLWFIGILWISSNWFQSMGWPPATKMLTHWFASKELGTKWAMGTTSNQI
GGAIAMISCGYLIDKFDWRAAFFVPGVVACVVSLFLYNRLRNSPKEVGLSTVEEYKEYPPESIGDYEKLLTPQLLRMVFC
NRLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGFLSDKLFQGRRGPIGAICMVL
LSLLLVLFWTIPIQSELLSIVILSLIGFFVAGPQLLVGIAAADFSTRQAVGTANGLSGLFGYLGASIAGIGVGWISDHYG
WNGVFIFFSISALLGGGLFALTWNRSAKK

Sequences:

>Translated_429_residues
MTDTKPKIKTPRSPYVKKYNSWRVRILYSIIIGYATFYLCRQNFNIATPAIREYFGVTKTQIGWILTASSIMYGVSKACN
GFISDKVNARIFMVLGLLVVGIITILIGFSYSLWFIGILWISSNWFQSMGWPPATKMLTHWFASKELGTKWAMGTTSNQI
GGAIAMISCGYLIDKFDWRAAFFVPGVVACVVSLFLYNRLRNSPKEVGLSTVEEYKEYPPESIGDYEKLLTPQLLRMVFC
NRLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGFLSDKLFQGRRGPIGAICMVL
LSLLLVLFWTIPIQSELLSIVILSLIGFFVAGPQLLVGIAAADFSTRQAVGTANGLSGLFGYLGASIAGIGVGWISDHYG
WNGVFIFFSISALLGGGLFALTWNRSAKK
>Mature_428_residues
TDTKPKIKTPRSPYVKKYNSWRVRILYSIIIGYATFYLCRQNFNIATPAIREYFGVTKTQIGWILTASSIMYGVSKACNG
FISDKVNARIFMVLGLLVVGIITILIGFSYSLWFIGILWISSNWFQSMGWPPATKMLTHWFASKELGTKWAMGTTSNQIG
GAIAMISCGYLIDKFDWRAAFFVPGVVACVVSLFLYNRLRNSPKEVGLSTVEEYKEYPPESIGDYEKLLTPQLLRMVFCN
RLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGFLSDKLFQGRRGPIGAICMVLL
SLLLVLFWTIPIQSELLSIVILSLIGFFVAGPQLLVGIAAADFSTRQAVGTANGLSGLFGYLGASIAGIGVGWISDHYGW
NGVFIFFSISALLGGGLFALTWNRSAKK

Specific function: Transport protein for sugar phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=399, Percent_Identity=26.8170426065163, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI4503847, Length=399, Percent_Identity=26.8170426065163, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI256219483, Length=399, Percent_Identity=26.8170426065163, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI256219543, Length=421, Percent_Identity=25.8907363420428, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI256219564, Length=329, Percent_Identity=26.4437689969605, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI38093649, Length=386, Percent_Identity=23.3160621761658, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI223717983, Length=386, Percent_Identity=23.3160621761658, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI46361976, Length=401, Percent_Identity=24.4389027431421, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788573, Length=424, Percent_Identity=34.9056603773585, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI87082310, Length=412, Percent_Identity=37.378640776699, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI2367259, Length=431, Percent_Identity=30.1624129930394, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=22.4390243902439, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI2367379, Length=318, Percent_Identity=24.5283018867925, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789515, Length=423, Percent_Identity=23.1678486997636, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789152, Length=431, Percent_Identity=21.8097447795824, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI2367193, Length=423, Percent_Identity=20.3309692671395, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=430, Percent_Identity=22.3255813953488, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17561094, Length=398, Percent_Identity=22.6130653266332, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI133901856, Length=430, Percent_Identity=20.9302325581395, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI133901854, Length=430, Percent_Identity=20.9302325581395, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI133930953, Length=379, Percent_Identity=24.802110817942, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564202, Length=348, Percent_Identity=21.264367816092, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=348, Percent_Identity=21.264367816092, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656866, Length=454, Percent_Identity=22.0264317180617, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550478, Length=454, Percent_Identity=22.0264317180617, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656861, Length=454, Percent_Identity=22.0264317180617, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47555; Mature: 47424

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTKPKIKTPRSPYVKKYNSWRVRILYSIIIGYATFYLCRQNFNIATPAIREYFGVTKT
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHH
QIGWILTASSIMYGVSKACNGFISDKVNARIFMVLGLLVVGIITILIGFSYSLWFIGILW
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSNWFQSMGWPPATKMLTHWFASKELGTKWAMGTTSNQIGGAIAMISCGYLIDKFDWRA
HCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHCCHHHHHHHHHHHHCCCCCH
AFFVPGVVACVVSLFLYNRLRNSPKEVGLSTVEEYKEYPPESIGDYEKLLTPQLLRMVFC
HHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NRLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGF
HHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCHHHCCCCHHHHHHHHCCCHHHHHHH
LSDKLFQGRRGPIGAICMVLLSLLLVLFWTIPIQSELLSIVILSLIGFFVAGPQLLVGIA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AADFSTRQAVGTANGLSGLFGYLGASIAGIGVGWISDHYGWNGVFIFFSISALLGGGLFA
HHCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCEEE
LTWNRSAKK
EEECCCCCC
>Mature Secondary Structure 
TDTKPKIKTPRSPYVKKYNSWRVRILYSIIIGYATFYLCRQNFNIATPAIREYFGVTKT
CCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHH
QIGWILTASSIMYGVSKACNGFISDKVNARIFMVLGLLVVGIITILIGFSYSLWFIGILW
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISSNWFQSMGWPPATKMLTHWFASKELGTKWAMGTTSNQIGGAIAMISCGYLIDKFDWRA
HCCHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHCCHHHHHHHHHHHHCCCCCH
AFFVPGVVACVVSLFLYNRLRNSPKEVGLSTVEEYKEYPPESIGDYEKLLTPQLLRMVFC
HHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NRLIWYVCLANMFVYIIRSGVIYWAPTFLKDLRNISLANAGLQIGLYEMIGIPGALIAGF
HHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCHHHCCCCHHHHHHHHCCCHHHHHHH
LSDKLFQGRRGPIGAICMVLLSLLLVLFWTIPIQSELLSIVILSLIGFFVAGPQLLVGIA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AADFSTRQAVGTANGLSGLFGYLGASIAGIGVGWISDHYGWNGVFIFFSISALLGGGLFA
HHCCHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHCCCEEE
LTWNRSAKK
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]