| Definition | Rickettsia akari str. Hartford, complete genome. |
|---|---|
| Accession | NC_009881 |
| Length | 1,231,060 |
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The map label for this gene is rfbB [H]
Identifier: 157825128
GI number: 157825128
Start: 1389
End: 2138
Strand: Direct
Name: rfbB [H]
Synonym: A1C_00015
Alternate gene names: 157825128
Gene position: 1389-2138 (Clockwise)
Preceding gene: 157825127
Following gene: 157825129
Centisome position: 0.11
GC content: 29.87
Gene sequence:
>750_bases ATGTCACTTAGCCATTCAAAAGTATTTATAGAAATAACAAATGGTTATGTAGAAGGTGTAGATACTCATAAAAGAGCTCA AGGTTTAAAGGCTTTTTTCTTGAAAAAAGGGGTTTGTCTTTCTCCAAATATACCTATATTAAACGATATTAACTTTTCTT GCCAAGAAGGAGAAAAAATAGCTTTTATAGGAAGTAACGGTTCCGGAAAAAGCTCTCTTTTGAAGCTAATCGCTGGAATA TATCCGTTAAAATCTGGTACAGTTAAGGTTCATGGAGATATTGCTGCAATTATAGATATGGGAGTCGGTTTTGAGCCGGA ACAAACTGGCCGTGAAAATATAAAAATGTTGATGCTATATAATAATATGTTAGATAAATATAGCAGAAAAATTGAAAATG AGATTATAGATTTTTCGGAACTAGGTAATAAAATCGACTTACCGATAAAAAATTATAGTTCAGGAATGTTATCACGACTT GCTTTTTCTGTATCAATATTTCAAAATCCCCAAATTCTATTACTTGATGAAATTTTTGCAGCAGGAGATAGCTGTTTTGT AGAGAAATCTATTAATTTAATGAAAAGTAAATTTAAAAATACCCCTATTTCAATAATAGTAAGTCATCAAGAAGAAATTA TAAAAGATAATTGCGAGAGATGTATTTTATTGAAAGACGGAAATATTATAGGTGATGGTACACCATCGGAAATGTTTAAA ATCTATAATCAACAACAAGGGAATTCATAA
Upstream 100 bases:
>100_bases CGATAATGTTATTTAAAAACGGTGAACAAAAAGATACTAAAATAGGTTTGCAGCAAAAAAACTCTCTTTTAGATTGGATT AATAAATCTGTTTAATAGTT
Downstream 100 bases:
>100_bases ATGATAAGGTATTTTTTTTCTAAAAAATACTGGCGGGCAATAGCATTACTAGTTAAAGCTTCTATAATTAGGCAAAATAA GGATTCTTTTTTAGGTTCTT
Product: O-antigen export system ATP-binding protein RfbE
Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 249; Mature: 248
Protein sequence:
>249_residues MSLSHSKVFIEITNGYVEGVDTHKRAQGLKAFFLKKGVCLSPNIPILNDINFSCQEGEKIAFIGSNGSGKSSLLKLIAGI YPLKSGTVKVHGDIAAIIDMGVGFEPEQTGRENIKMLMLYNNMLDKYSRKIENEIIDFSELGNKIDLPIKNYSSGMLSRL AFSVSIFQNPQILLLDEIFAAGDSCFVEKSINLMKSKFKNTPISIIVSHQEEIIKDNCERCILLKDGNIIGDGTPSEMFK IYNQQQGNS
Sequences:
>Translated_249_residues MSLSHSKVFIEITNGYVEGVDTHKRAQGLKAFFLKKGVCLSPNIPILNDINFSCQEGEKIAFIGSNGSGKSSLLKLIAGI YPLKSGTVKVHGDIAAIIDMGVGFEPEQTGRENIKMLMLYNNMLDKYSRKIENEIIDFSELGNKIDLPIKNYSSGMLSRL AFSVSIFQNPQILLLDEIFAAGDSCFVEKSINLMKSKFKNTPISIIVSHQEEIIKDNCERCILLKDGNIIGDGTPSEMFK IYNQQQGNS >Mature_248_residues SLSHSKVFIEITNGYVEGVDTHKRAQGLKAFFLKKGVCLSPNIPILNDINFSCQEGEKIAFIGSNGSGKSSLLKLIAGIY PLKSGTVKVHGDIAAIIDMGVGFEPEQTGRENIKMLMLYNNMLDKYSRKIENEIIDFSELGNKIDLPIKNYSSGMLSRLA FSVSIFQNPQILLLDEIFAAGDSCFVEKSINLMKSKFKNTPISIIVSHQEEIIKDNCERCILLKDGNIIGDGTPSEMFKI YNQQQGNS
Specific function: May form an ATP-driven O-antigen export apparatus, in association with RfbA [H]
COG id: COG1134
COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI157502203, Length=225, Percent_Identity=28, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI157502201, Length=225, Percent_Identity=28, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI89111135, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI27436953, Length=188, Percent_Identity=23.936170212766, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI9961250, Length=232, Percent_Identity=25.4310344827586, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI4505771, Length=232, Percent_Identity=25.4310344827586, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI9961252, Length=232, Percent_Identity=25.4310344827586, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI153792144, Length=217, Percent_Identity=23.0414746543779, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI27477115, Length=190, Percent_Identity=23.1578947368421, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=23.2227488151659, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI6005701, Length=190, Percent_Identity=22.6315789473684, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI21729876, Length=209, Percent_Identity=29.6650717703349, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI21729873, Length=209, Percent_Identity=29.6650717703349, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI15149474, Length=209, Percent_Identity=29.6650717703349, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI66529005, Length=203, Percent_Identity=26.1083743842365, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI27262624, Length=214, Percent_Identity=25.7009345794392, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI27262626, Length=214, Percent_Identity=25.7009345794392, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI48995001, Length=238, Percent_Identity=25.2100840336134, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI48994943, Length=206, Percent_Identity=25.2427184466019, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1786398, Length=219, Percent_Identity=25.1141552511416, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1788210, Length=210, Percent_Identity=27.1428571428571, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1789593, Length=212, Percent_Identity=22.6415094339623, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1789032, Length=214, Percent_Identity=27.5700934579439, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1788225, Length=219, Percent_Identity=24.6575342465753, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1787370, Length=207, Percent_Identity=23.6714975845411, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1790467, Length=203, Percent_Identity=25.1231527093596, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786563, Length=191, Percent_Identity=24.6073298429319, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787792, Length=210, Percent_Identity=26.1904761904762, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787547, Length=229, Percent_Identity=22.2707423580786, Blast_Score=63, Evalue=1e-11, Organism=Escherichia coli, GI1787105, Length=204, Percent_Identity=23.5294117647059, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1786703, Length=218, Percent_Identity=25.2293577981651, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17569081, Length=213, Percent_Identity=30.0469483568075, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI212646699, Length=254, Percent_Identity=30.3149606299213, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17551702, Length=219, Percent_Identity=28.7671232876712, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17551700, Length=219, Percent_Identity=28.7671232876712, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI25146765, Length=209, Percent_Identity=30.1435406698565, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71992070, Length=209, Percent_Identity=30.622009569378, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI71992066, Length=209, Percent_Identity=30.622009569378, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI86564969, Length=209, Percent_Identity=30.622009569378, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17533971, Length=216, Percent_Identity=26.8518518518519, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI115535101, Length=217, Percent_Identity=26.7281105990783, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17565938, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI281363262, Length=239, Percent_Identity=26.3598326359833, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24653245, Length=239, Percent_Identity=26.3598326359833, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24582014, Length=234, Percent_Identity=26.4957264957265, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24582012, Length=234, Percent_Identity=26.4957264957265, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281362751, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24650853, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24650855, Length=210, Percent_Identity=25.2380952380952, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24585557, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI45552437, Length=206, Percent_Identity=29.126213592233, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI28574259, Length=205, Percent_Identity=25.8536585365854, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: 3.6.3.25 [C]
Molecular weight: Translated: 27579; Mature: 27448
Theoretical pI: Translated: 6.91; Mature: 6.91
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 5.2 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLSHSKVFIEITNGYVEGVDTHKRAQGLKAFFLKKGVCLSPNIPILNDINFSCQEGEKI CCCCCCEEEEEEECCEECCCCHHHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEE AFIGSNGSGKSSLLKLIAGIYPLKSGTVKVHGDIAAIIDMGVGFEPEQTGRENIKMLMLY EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCCCCCCEEEEEHH NNMLDKYSRKIENEIIDFSELGNKIDLPIKNYSSGMLSRLAFSVSIFQNPQILLLDEIFA HHHHHHHHHHHHHHCCCHHHCCCEECCCCCCCCHHHHHHHHHHEEEECCCCEEEEEHHHH AGDSCFVEKSINLMKSKFKNTPISIIVSHQEEIIKDNCERCILLKDGNIIGDGTPSEMFK CCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCEEEEEECCCEECCCCHHHHHH IYNQQQGNS HHHHCCCCC >Mature Secondary Structure SLSHSKVFIEITNGYVEGVDTHKRAQGLKAFFLKKGVCLSPNIPILNDINFSCQEGEKI CCCCCEEEEEEECCEECCCCHHHHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEE AFIGSNGSGKSSLLKLIAGIYPLKSGTVKVHGDIAAIIDMGVGFEPEQTGRENIKMLMLY EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCCCCCCEEEEEHH NNMLDKYSRKIENEIIDFSELGNKIDLPIKNYSSGMLSRLAFSVSIFQNPQILLLDEIFA HHHHHHHHHHHHHHCCCHHHCCCEECCCCCCCCHHHHHHHHHHEEEECCCCEEEEEHHHH AGDSCFVEKSINLMKSKFKNTPISIIVSHQEEIIKDNCERCILLKDGNIIGDGTPSEMFK CCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCEEEEEECCCEECCCCHHHHHH IYNQQQGNS HHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]
Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 8626291 [H]