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The map label for this gene is glnL [H]

Identifier: 157373113

GI number: 157373113

Start: 5410275

End: 5411324

Strand: Direct

Name: glnL [H]

Synonym: Spro_4882

Alternate gene names: 157373113

Gene position: 5410275-5411324 (Clockwise)

Preceding gene: 157373112

Following gene: 157373114

Centisome position: 99.29

GC content: 58.76

Gene sequence:

>1050_bases
ATGGCAACTGGCAAGCTGCCCGATGCTGGGCAGATCCTCAATTCTCTCATCAACAGCATCCTGCTGTTGGATGACTCGCT
GGCGGTTCATTACGCCAATCCGGCGGCACAACAACTGCTGGCACAAAGTTCCCGTAAACTTTTCGGTACACCGTTACCCG
ATCTGCTCGGCTATTTTTCGCTGAATGTCGATCTGATGCGTGAGAGCCTGCGCGCTGGCCAGGGCTTTACCGATAGCGAA
GTGACCCTGGTGGTTGACGGGCGCGCGCATATCCTCTCCCTGACCGCCCAGACGCTGTCTGAAGGCTATATCCTGATCGA
ACTGGCGCCGATGGATAACCAACGTCGCCTGAGCCAGGAACAGCTGCAGCATGCCCAGCAGGTTGCCGCCCGCGATCTGG
TTCGTGGCCTGGCGCATGAGATTAAAAATCCGCTTGGCGGGCTGCGCGGTGCGGCGCAGTTGCTGGCCAAGGCTCTGCCC
GATCCGTCGCTGACCGAATACACCAAGGTGATCATTGAACAGGCCGACCGCCTGCGCAATCTGGTCGATCGCCTGCTGGG
CCCGCAACGGCCAGGCCAGCACATTACTCAAAGTATTCATCAGGTGGCGGAGCGAGTCTGCCAACTGGTGTCGCTGGAGA
AGCCGGATAACGTAACGCTGGTACGCGACTACGACCCGAGCCTGCCGGAGTTGGCGCACGACCCGGATCAAATCGAACAG
GTGCTGCTGAACATCACTCGCAATGCGCTGCAGGCGCTGGGTGAAGCCGGTGGCACCATTACGCTGCGCACCCGAACCGC
ATTCCAGATCACCCTGCACGGCACCCGCTACCGGTTAGCGGCACGTATCGATATTGAAGATGACGGCCCCGGCGTACCGG
CGCAGTTGCAGGACACGCTGTTTTACCCAATGGTCAGCGGCCGCGAAGGCGGAACCGGCCTGGGTTTATCCATCGCCCGT
AATCTTATCGATCAGCATTGCGGAAAAATTGAATTTAACAGTTGGCCAGGACATACCGAATTCTCGGTTTACCTGCCTAT
TCGCCAGTGA

Upstream 100 bases:

>100_bases
GGTTTTTTTCTCCACCGTATTTTCTGCAAAACTATTCCGTGCCGCACGCAGGGCGGATGGAGTAGGATAGATGCACTAAA
AAGGTGCAGGAGTCTGCTAT

Downstream 100 bases:

>100_bases
GGTTTTCTATGCAACGAGGGATAGTCTGGATCGTCGATGACGATAGCTCCATCCGCTGGGTGCTTGAACGCGCGCTCACT
GGAGCGGGTGTGAGTTGCGT

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MATGKLPDAGQILNSLINSILLLDDSLAVHYANPAAQQLLAQSSRKLFGTPLPDLLGYFSLNVDLMRESLRAGQGFTDSE
VTLVVDGRAHILSLTAQTLSEGYILIELAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALP
DPSLTEYTKVIIEQADRLRNLVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLVRDYDPSLPELAHDPDQIEQ
VLLNITRNALQALGEAGGTITLRTRTAFQITLHGTRYRLAARIDIEDDGPGVPAQLQDTLFYPMVSGREGGTGLGLSIAR
NLIDQHCGKIEFNSWPGHTEFSVYLPIRQ

Sequences:

>Translated_349_residues
MATGKLPDAGQILNSLINSILLLDDSLAVHYANPAAQQLLAQSSRKLFGTPLPDLLGYFSLNVDLMRESLRAGQGFTDSE
VTLVVDGRAHILSLTAQTLSEGYILIELAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALP
DPSLTEYTKVIIEQADRLRNLVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLVRDYDPSLPELAHDPDQIEQ
VLLNITRNALQALGEAGGTITLRTRTAFQITLHGTRYRLAARIDIEDDGPGVPAQLQDTLFYPMVSGREGGTGLGLSIAR
NLIDQHCGKIEFNSWPGHTEFSVYLPIRQ
>Mature_348_residues
ATGKLPDAGQILNSLINSILLLDDSLAVHYANPAAQQLLAQSSRKLFGTPLPDLLGYFSLNVDLMRESLRAGQGFTDSEV
TLVVDGRAHILSLTAQTLSEGYILIELAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALPD
PSLTEYTKVIIEQADRLRNLVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLVRDYDPSLPELAHDPDQIEQV
LLNITRNALQALGEAGGTITLRTRTAFQITLHGTRYRLAARIDIEDDGPGVPAQLQDTLFYPMVSGREGGTGLGLSIARN
LIDQHCGKIEFNSWPGHTEFSVYLPIRQ

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=85.3868194842407, Blast_Score=614, Evalue=1e-177,
Organism=Escherichia coli, GI1788549, Length=349, Percent_Identity=28.080229226361, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=31.3807531380753, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081816, Length=276, Percent_Identity=30.0724637681159, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=289, Percent_Identity=25.2595155709343, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=26.8595041322314, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=29.5652173913043, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=26.2096774193548, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=24.0909090909091, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38310; Mature: 38179

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGKLPDAGQILNSLINSILLLDDSLAVHYANPAAQQLLAQSSRKLFGTPLPDLLGYFS
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNVDLMRESLRAGQGFTDSEVTLVVDGRAHILSLTAQTLSEGYILIELAPMDNQRRLSQE
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHH
QLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALPDPSLTEYTKVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLVRDYDPSLPELAHDPDQIEQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHCCCHHHHHH
VLLNITRNALQALGEAGGTITLRTRTAFQITLHGTRYRLAARIDIEDDGPGVPAQLQDTL
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCEEEEEEEEEECCCCCCCCHHHHHHH
FYPMVSGREGGTGLGLSIARNLIDQHCGKIEFNSWPGHTEFSVYLPIRQ
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure 
ATGKLPDAGQILNSLINSILLLDDSLAVHYANPAAQQLLAQSSRKLFGTPLPDLLGYFS
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNVDLMRESLRAGQGFTDSEVTLVVDGRAHILSLTAQTLSEGYILIELAPMDNQRRLSQE
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHH
QLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLAKALPDPSLTEYTKVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LVDRLLGPQRPGQHITQSIHQVAERVCQLVSLEKPDNVTLVRDYDPSLPELAHDPDQIEQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHCCCHHHHHH
VLLNITRNALQALGEAGGTITLRTRTAFQITLHGTRYRLAARIDIEDDGPGVPAQLQDTL
HHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCEEEEEEEEEECCCCCCCCHHHHHHH
FYPMVSGREGGTGLGLSIARNLIDQHCGKIEFNSWPGHTEFSVYLPIRQ
HHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]