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The map label for this gene is recG [H]

Identifier: 157373102

GI number: 157373102

Start: 5394230

End: 5396311

Strand: Direct

Name: recG [H]

Synonym: Spro_4871

Alternate gene names: 157373102

Gene position: 5394230-5396311 (Clockwise)

Preceding gene: 157373101

Following gene: 157373104

Centisome position: 99.0

GC content: 58.69

Gene sequence:

>2082_bases
ATGAAAGGCCGCCTGCTGGATGCTGTCCCACTCACCACACTTTCCGGCGTGGGTGCCAGCCAGGCGGGAAAACTGGCCAA
AATTGGCCTGGAAACCATTCAGGATTTGCTGCTGCACCTGCCACTGCGCTACGAAGACCGCACCCGCCTCTATCCAATAA
ACGACCTGCAGCCAGGCATTTTTGCCACGGTGGAAGGTGAAGTACTGCGTACGGACATCAGTTTTGGCCGTCGACGTATG
CTGACCTGCCAGATCAGTGACGGTACCGGCCTGCTCACCATGCGCTTCTTCAACTTCAATGCGGCGATGAAAAACAGCCT
GGCAACCGGCCGTCGCGTAACCGCCTATGGTGAAGTCAAACGCGGCAATCACGGCGCAGAAATTATTCACCCGGAATACC
GTATTCAGGGAGAAAGCAGCGAGGTTGAGCTGCAAGAGTCACTGACCCCGGTCTACCCAACGACTGAAGGTATCCGGCAG
GCTACGCTGCGCAAGCTGACCGATCAGGCTCTGGAACTGTTGGATACCTGCGCCATCACCGAGCTGCTGCCGTCGGAACT
GAGCGGTGGTTTGATGAGTCTGCCACAGGCATTGCATACCCTGCACCGCCCGCCGCCGGATATCCAGCTGGTTGATTTGG
AACAGGGCAAACACCCGGCGCAAAAACGACTGATCATGGAAGAGCTGCTGGCGCATAACCTCAGTATGCTGGCGGTACGC
GCCGGCGCTCAGAGCTATCAGGCGCTGCCTCTGATGCCGGATGATCGGCTTAAAACACAATTTCTCGCCCAGTTACCCTT
TACACCGACCGGCGCCCAAGACCGCGTGGTGGCCGATATAGAAGCCGATATGCAAAAAGGCTTCCCGATGATGCGCCTGG
TACAGGGCGACGTCGGCTCCGGTAAAACGTTGGTGGCCGCACTGGCCGCGCTACGCGCTATCGCCCACGGCAAGCAGGTG
GCATTGATGGCGCCTACGGAACTGCTGGCCGAACAGCATGCCAACAATTTCCGCCAGTGGTTTGAACCGCTGGGATTAGA
AGTTGGCTGGCTGGCCGGCAAGCAAAAAGGCAAGGCGCGTATCGCACAGCAAGAGGCTATTGCCAGTGGTCAGGTGTCGA
TGGTGGTCGGCACGCACGCCATCTTCCAGGAACAGGTGAAATTTTCCGGCCTGGCACTGGTGATCATCGACGAACAGCAC
CGTTTTGGCGTCCACCAGCGACTGGCACTGTGGGAAAAGGGGGAGGAGCAAGGCTTCCATGCCCATCAGTTGATCATGAC
CGCCACGCCCATCCCACGCACGCTGGCAATGACCGCCTATGCCGATCTCGACACCTCGGTGATCGACGAGCTGCCCCCGG
GCAGAACGCCGGTCACTACCGTCGCGATACCCGATACCCGGCGCGCCGATATAATCCAGCGGGTGAAAAGCGCCTGCCTG
GAAGAAGGCCGGCAAGCATATTGGGTTTGCACGCTGATCGAAGAGTCTGAACTACTCGAAGCCCAGGCCGCAGAAGCCAC
CTGGGAAGAGCTGAAAACCGCGCTGCCGGAGCTGAAAGTCGCGTTGATACATGGCCGAATGAAAGCGCAAGAGAAGCAGG
CGGTGATGCAGGCCTTTAAACAAGGCGAGCTCCAGCTGTTGGTGGCGACGACGGTGATCGAAGTCGGTGTCGACGTGCCG
AATGCCAGCCTGATGATCATCGAAAACCCGGAGCGGTTAGGACTGGCACAGTTGCATCAGCTGCGTGGCCGCGTGGGCCG
TGGTGCCGTGGCGTCACATTGCGTGTTGCTGTACAAAACGCCACTGAGCAAAACCGCACAGAAGCGGCTGCAGGTGCTGC
GTGACAGCAATGACGGCTTCGTCATTGCCCAGCAGGATCTGGAGATCCGTGGCCCCGGGGAGCTGCTTGGCACACGCCAA
ACCGGCAGCGCCGAGTTTAAGGTAGCCGATTTACTACGCGATCAGGCGATGATCCCGGAAGTACAACGCGTCGCTCGTCA
TATCCATCAGCAATATCCGCAACATGCCCACGCCCTGATTGAACGCTGGTTACCGGAAAAAGCGCGTTACTCAAACGCCT
AA

Upstream 100 bases:

>100_bases
TGGCCAAACGTAAAAGACTGCCGCGTCCGCACATTGATGAACAGGGCCAGGTGGTCGCCGATGCCGAATGGTGGGCAGCC
ATGCAAGCGACGGTACGCAA

Downstream 100 bases:

>100_bases
TTCCCTGCCAAAACAAAGGGCGCCAATCGGCGCCCTTCTGGTTTATTGCAATCTGCTAATCAACCTATCGTCGGGAACAC
CGGCAACAGCAGATACAGCT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKGRLLDAVPLTTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYPINDLQPGIFATVEGEVLRTDISFGRRRM
LTCQISDGTGLLTMRFFNFNAAMKNSLATGRRVTAYGEVKRGNHGAEIIHPEYRIQGESSEVELQESLTPVYPTTEGIRQ
ATLRKLTDQALELLDTCAITELLPSELSGGLMSLPQALHTLHRPPPDIQLVDLEQGKHPAQKRLIMEELLAHNLSMLAVR
AGAQSYQALPLMPDDRLKTQFLAQLPFTPTGAQDRVVADIEADMQKGFPMMRLVQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHANNFRQWFEPLGLEVGWLAGKQKGKARIAQQEAIASGQVSMVVGTHAIFQEQVKFSGLALVIIDEQH
RFGVHQRLALWEKGEEQGFHAHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRADIIQRVKSACL
EEGRQAYWVCTLIEESELLEAQAAEATWEELKTALPELKVALIHGRMKAQEKQAVMQAFKQGELQLLVATTVIEVGVDVP
NASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQKRLQVLRDSNDGFVIAQQDLEIRGPGELLGTRQ
TGSAEFKVADLLRDQAMIPEVQRVARHIHQQYPQHAHALIERWLPEKARYSNA

Sequences:

>Translated_693_residues
MKGRLLDAVPLTTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYPINDLQPGIFATVEGEVLRTDISFGRRRM
LTCQISDGTGLLTMRFFNFNAAMKNSLATGRRVTAYGEVKRGNHGAEIIHPEYRIQGESSEVELQESLTPVYPTTEGIRQ
ATLRKLTDQALELLDTCAITELLPSELSGGLMSLPQALHTLHRPPPDIQLVDLEQGKHPAQKRLIMEELLAHNLSMLAVR
AGAQSYQALPLMPDDRLKTQFLAQLPFTPTGAQDRVVADIEADMQKGFPMMRLVQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHANNFRQWFEPLGLEVGWLAGKQKGKARIAQQEAIASGQVSMVVGTHAIFQEQVKFSGLALVIIDEQH
RFGVHQRLALWEKGEEQGFHAHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRADIIQRVKSACL
EEGRQAYWVCTLIEESELLEAQAAEATWEELKTALPELKVALIHGRMKAQEKQAVMQAFKQGELQLLVATTVIEVGVDVP
NASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQKRLQVLRDSNDGFVIAQQDLEIRGPGELLGTRQ
TGSAEFKVADLLRDQAMIPEVQRVARHIHQQYPQHAHALIERWLPEKARYSNA
>Mature_693_residues
MKGRLLDAVPLTTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYPINDLQPGIFATVEGEVLRTDISFGRRRM
LTCQISDGTGLLTMRFFNFNAAMKNSLATGRRVTAYGEVKRGNHGAEIIHPEYRIQGESSEVELQESLTPVYPTTEGIRQ
ATLRKLTDQALELLDTCAITELLPSELSGGLMSLPQALHTLHRPPPDIQLVDLEQGKHPAQKRLIMEELLAHNLSMLAVR
AGAQSYQALPLMPDDRLKTQFLAQLPFTPTGAQDRVVADIEADMQKGFPMMRLVQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHANNFRQWFEPLGLEVGWLAGKQKGKARIAQQEAIASGQVSMVVGTHAIFQEQVKFSGLALVIIDEQH
RFGVHQRLALWEKGEEQGFHAHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRADIIQRVKSACL
EEGRQAYWVCTLIEESELLEAQAAEATWEELKTALPELKVALIHGRMKAQEKQAVMQAFKQGELQLLVATTVIEVGVDVP
NASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQKRLQVLRDSNDGFVIAQQDLEIRGPGELLGTRQ
TGSAEFKVADLLRDQAMIPEVQRVARHIHQQYPQHAHALIERWLPEKARYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=83.982683982684, Blast_Score=1178, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=429, Percent_Identity=38.2284382284382, Blast_Score=249, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76552; Mature: 76552

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRLLDAVPLTTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYPINDLQPGI
CCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCE
FATVEGEVLRTDISFGRRRMLTCQISDGTGLLTMRFFNFNAAMKNSLATGRRVTAYGEVK
EEEECCCEEEECHHCCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHCCCCEEEEEECCC
RGNHGAEIIHPEYRIQGESSEVELQESLTPVYPTTEGIRQATLRKLTDQALELLDTCAIT
CCCCCCEEECCCEEECCCCCCEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPSELSGGLMSLPQALHTLHRPPPDIQLVDLEQGKHPAQKRLIMEELLAHNLSMLAVR
HHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHEEEC
AGAQSYQALPLMPDDRLKTQFLAQLPFTPTGAQDRVVADIEADMQKGFPMMRLVQGDVGS
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHCCCCEEEHHCCCCCC
GKTLVAALAALRAIAHGKQVALMAPTELLAEQHANNFRQWFEPLGLEVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
IAQQEAIASGQVSMVVGTHAIFQEQVKFSGLALVIIDEQHRFGVHQRLALWEKGEEQGFH
HHHHHHHCCCCEEEEEHHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
AHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRADIIQRVKSACL
HHEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
EEGRQAYWVCTLIEESELLEAQAAEATWEELKTALPELKVALIHGRMKAQEKQAVMQAFK
HCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGELQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKT
CCCEEEEEEHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHCCCCCCHHHHCEEEEEEC
PLSKTAQKRLQVLRDSNDGFVIAQQDLEIRGPGELLGTRQTGSAEFKVADLLRDQAMIPE
CCHHHHHHHHHHHHCCCCCEEEEECCCEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRVARHIHQQYPQHAHALIERWLPEKARYSNA
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKGRLLDAVPLTTLSGVGASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYPINDLQPGI
CCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCE
FATVEGEVLRTDISFGRRRMLTCQISDGTGLLTMRFFNFNAAMKNSLATGRRVTAYGEVK
EEEECCCEEEECHHCCCEEEEEEEECCCCCEEEEEEECCCHHHHHHHCCCCEEEEEECCC
RGNHGAEIIHPEYRIQGESSEVELQESLTPVYPTTEGIRQATLRKLTDQALELLDTCAIT
CCCCCCEEECCCEEECCCCCCEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPSELSGGLMSLPQALHTLHRPPPDIQLVDLEQGKHPAQKRLIMEELLAHNLSMLAVR
HHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHEEEC
AGAQSYQALPLMPDDRLKTQFLAQLPFTPTGAQDRVVADIEADMQKGFPMMRLVQGDVGS
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHCCCCEEEHHCCCCCC
GKTLVAALAALRAIAHGKQVALMAPTELLAEQHANNFRQWFEPLGLEVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
IAQQEAIASGQVSMVVGTHAIFQEQVKFSGLALVIIDEQHRFGVHQRLALWEKGEEQGFH
HHHHHHHCCCCEEEEEHHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
AHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRADIIQRVKSACL
HHEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHH
EEGRQAYWVCTLIEESELLEAQAAEATWEELKTALPELKVALIHGRMKAQEKQAVMQAFK
HCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGELQLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKT
CCCEEEEEEHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHCCCCCCHHHHCEEEEEEC
PLSKTAQKRLQVLRDSNDGFVIAQQDLEIRGPGELLGTRQTGSAEFKVADLLRDQAMIPE
CCHHHHHHHHHHHHCCCCCEEEEECCCEECCCHHHCCCCCCCCCCHHHHHHHHHHHCCHH
VQRVARHIHQQYPQHAHALIERWLPEKARYSNA
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]