| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is spoT [H]
Identifier: 157373100
GI number: 157373100
Start: 5391421
End: 5393532
Strand: Direct
Name: spoT [H]
Synonym: Spro_4869
Alternate gene names: 157373100
Gene position: 5391421-5393532 (Clockwise)
Preceding gene: 157373099
Following gene: 157373101
Centisome position: 98.95
GC content: 54.69
Gene sequence:
>2112_bases TTGTACCTGTTTGAAAGCCTGAATCTGCTGATTCAACGTTACCTGCCTGAGGAGCAGATTAAGCGCCTCAAACAGGCATA CCTCGTTGCACGTGATGCTCACGAGGGACAGACACGCTCCAGCGGTGAGCCCTACATTACTCACCCGGTTGCCGTGGCCT GCATTCTGGCGGAAATGCGTCTCGATCATGAGACGCTGATGGCAGCACTGCTGCACGACGTCATCGAAGATACCCCGGCC ACCTACCAGGATATGGAACAGCTATTCGGCAAAAGCGTTGCCGAACTGGTTGAAGGCGTATCCAAGCTCGACAAGCTGAA GTTCCAGGATAAAAAAGAAGCTCAGGCGGAAAACTTCCGCAAGATGATCATGGCGATGGTGCAGGATATCCGCGTCGTGC TGATCAAGCTGGCCGACCGTACGCACAACATGCGCACTCTCGGTTCGCTGCGTCCTGACAAACGGCGGCGTATTGCACGT GAAACCCTGGAAATCTACAGCCCCCTGGCCCATCGCCTGGGTATTCACCACCTGAAAACCGAGCTGGAAGAGCTGGGTTT TGAGGCGTTGTACCCGAACCGCTATCGCGTAATCAAAGAAGTGGTGAAAGCCGCACGCGGTAACCGTAAAGAGATGATCC AGAAGATTCTCTCCGAGATCGAAGGGCGACTGACCGAGGCCGGCATTCCCTGCCGCGTCAGCGGACGGGAAAAACATCTG TATTCCATCTACCTCAAGATGCACCTGAAAGAACAGCGTTTCCATTCGATTATGGATATCTACGCGTTCCGGGTGATCGT GAAGGAAGTCGACACCTGCTACCGCGTGCTGGGCCAGGCTCACAGCCTGTACAAACCGCGTCCGGGCAGGGTCAAAGACT ATATCGCCATTCCCAAGGCCAACGGCTATCAATCGCTGCACACCTCACTGATCGGCCCACATGGCGTACCGGTTGAAGTG CAGATCCGTACCGAAGATATGGATCAGATGGCCGAAATGGGGGTCGCCGCGCACTGGGCTTATAAAGAAAAAGAACAGGG CGAAACCGGCACCACCGCACAAATCCGCGCTCAGCGGTGGATGCAGAGCTTGCTGGAGCTGCAACAAAGCGCCGGCAGTT CGTTTGAATTTATCGAGAGCGTAAAATCCGATCTGTTCCCGGATGAGATTTACGTTTTCACCCCGGAAGGCCGCATTGTT GAATTGCCTGCGGGCGCAACGCCGGTCGACTTCGCCTACGCGGTGCACACCGATATCGGCCACGCCTGCGTTGGCGCACG TGTTGATCGCCAGCCATACCCGCTGTCACAGTCCTTGACCAGCGGGCAAACGGTCGAAATCATCACGGCTCCTGGTGCAC GGCCTAACGCCGCCTGGCTGAACTTTGTCGTCAGCTCAAAAGCGCGCGCAAAAATCCGCCAAATGCTGAAAAACCTCAAG CGCGATGATTCAGTCGGCCTCGGCCGCCGCTTGTTAAATCATGCATTGGGCGGCAGTCGCAAACTGGCAGAGGTTCCGGC AGAAAATATCCAACACGAGTTGGATCGCATGAAACTGGCGACGCTGGACGACCTGTTGGCTGAAATCGGCTTGGGCAATG CCATGAGCGTGGTGGTAGCGAAAAACCTGCAAGGTGACCAGTCTAATCTGGGGGCCTCCTCTGGGGTTCGTAATCTGGCG ATCAAGGGCTCAGACGGCGTGCTGATCACCTTCGCTAAATGCTGCCGACCTATTCCAGGCGATCCGATCATCGCCCACGT CAGCCCAGGCAAAGGCCTGGTGATCCACCATGAGTCCTGCCGAAATATCCGCGGCTACCAGAAAGAACCTGAAAAATTCA TGGCGGTAGAGTGGGATCAAGACATCGAACAGGAATTCATCGCCGAGATCAAAGTGGACATGTTTAATCATCAGGGGGCA CTGGCCAACCTGACGGCAGCCATCAATGCGGCTGAGTCCAATATTCAAAGCCTGAATACCGAAGAAAAAGACGGCCGGGT TTATAGTGCATTTATCCGTTTGACCACCCGCGATCGCATCCATCTGGCAAATATTATGCGTAAAATCCGTATCATGCCGG ATGTGATTAAAGTTAACCGTAACCGAAATTAG
Upstream 100 bases:
>100_bases GTTCGTGATCGTCAGGAGCAGCAAGAGCAGGAAGCCGCAGAGATTCAAGCGGTTACCGCCATTGCTGAAGGTCGTCGTTA ATTAGACTGCGAGTCTGCCT
Downstream 100 bases:
>100_bases CGCTTATGAGCCCTGAACGCTATGCGCGGATTTGTGAAATGCTGGCCACCCGGCAGCCGGATTTAACCGTCTGCCTGGAA CAGGTTCATAAACCGCATAA
Product: bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Products: NA
Alternate protein names: Penta-phosphate guanosine-3'-pyrophosphohydrolase; (ppGpp)ase [H]
Number of amino acids: Translated: 703; Mature: 703
Protein sequence:
>703_residues MYLFESLNLLIQRYLPEEQIKRLKQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMRLDHETLMAALLHDVIEDTPA TYQDMEQLFGKSVAELVEGVSKLDKLKFQDKKEAQAENFRKMIMAMVQDIRVVLIKLADRTHNMRTLGSLRPDKRRRIAR ETLEIYSPLAHRLGIHHLKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLTEAGIPCRVSGREKHL YSIYLKMHLKEQRFHSIMDIYAFRVIVKEVDTCYRVLGQAHSLYKPRPGRVKDYIAIPKANGYQSLHTSLIGPHGVPVEV QIRTEDMDQMAEMGVAAHWAYKEKEQGETGTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIV ELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQSLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQMLKNLK RDDSVGLGRRLLNHALGGSRKLAEVPAENIQHELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQGDQSNLGASSGVRNLA IKGSDGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDQDIEQEFIAEIKVDMFNHQGA LANLTAAINAAESNIQSLNTEEKDGRVYSAFIRLTTRDRIHLANIMRKIRIMPDVIKVNRNRN
Sequences:
>Translated_703_residues MYLFESLNLLIQRYLPEEQIKRLKQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMRLDHETLMAALLHDVIEDTPA TYQDMEQLFGKSVAELVEGVSKLDKLKFQDKKEAQAENFRKMIMAMVQDIRVVLIKLADRTHNMRTLGSLRPDKRRRIAR ETLEIYSPLAHRLGIHHLKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLTEAGIPCRVSGREKHL YSIYLKMHLKEQRFHSIMDIYAFRVIVKEVDTCYRVLGQAHSLYKPRPGRVKDYIAIPKANGYQSLHTSLIGPHGVPVEV QIRTEDMDQMAEMGVAAHWAYKEKEQGETGTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIV ELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQSLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQMLKNLK RDDSVGLGRRLLNHALGGSRKLAEVPAENIQHELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQGDQSNLGASSGVRNLA IKGSDGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDQDIEQEFIAEIKVDMFNHQGA LANLTAAINAAESNIQSLNTEEKDGRVYSAFIRLTTRDRIHLANIMRKIRIMPDVIKVNRNRN >Mature_703_residues MYLFESLNLLIQRYLPEEQIKRLKQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMRLDHETLMAALLHDVIEDTPA TYQDMEQLFGKSVAELVEGVSKLDKLKFQDKKEAQAENFRKMIMAMVQDIRVVLIKLADRTHNMRTLGSLRPDKRRRIAR ETLEIYSPLAHRLGIHHLKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLTEAGIPCRVSGREKHL YSIYLKMHLKEQRFHSIMDIYAFRVIVKEVDTCYRVLGQAHSLYKPRPGRVKDYIAIPKANGYQSLHTSLIGPHGVPVEV QIRTEDMDQMAEMGVAAHWAYKEKEQGETGTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIV ELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQSLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQMLKNLK RDDSVGLGRRLLNHALGGSRKLAEVPAENIQHELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQGDQSNLGASSGVRNLA IKGSDGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDQDIEQEFIAEIKVDMFNHQGA LANLTAAINAAESNIQSLNTEEKDGRVYSAFIRLTTRDRIHLANIMRKIRIMPDVIKVNRNRN
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into G
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HD domain [H]
Homologues:
Organism=Escherichia coli, GI1790082, Length=704, Percent_Identity=92.3295454545455, Blast_Score=1342, Evalue=0.0, Organism=Escherichia coli, GI1789147, Length=683, Percent_Identity=32.2108345534407, Blast_Score=384, Evalue=1e-108, Organism=Caenorhabditis elegans, GI25143118, Length=139, Percent_Identity=34.5323741007194, Blast_Score=69, Evalue=8e-12, Organism=Drosophila melanogaster, GI24650996, Length=123, Percent_Identity=40.650406504065, Blast_Score=78, Evalue=2e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012675 - InterPro: IPR003607 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =3.1.7.2 [H]
Molecular weight: Translated: 79267; Mature: 79267
Theoretical pI: Translated: 8.85; Mature: 8.85
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYLFESLNLLIQRYLPEEQIKRLKQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMR CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHH LDHETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSKLDKLKFQDKKEAQAENFR CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH KMIMAMVQDIRVVLIKLADRTHNMRTLGSLRPDKRRRIARETLEIYSPLAHRLGIHHLKT HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH ELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLTEAGIPCRVSGREKHL HHHHCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHH YSIYLKMHLKEQRFHSIMDIYAFRVIVKEVDTCYRVLGQAHSLYKPRPGRVKDYIAIPKA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCC NGYQSLHTSLIGPHGVPVEVQIRTEDMDQMAEMGVAAHWAYKEKEQGETGTTAQIRAQRW CCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHH MQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVELPAGATPVDFAYAVHTDIG HHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCCCHHHEEECCCCC HACVGARVDRQPYPLSQSLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQMLKNLK HHHHCCCCCCCCCCCCHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC RDDSVGLGRRLLNHALGGSRKLAEVPAENIQHELDRMKLATLDDLLAEIGLGNAMSVVVA CCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEE KNLQGDQSNLGASSGVRNLAIKGSDGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESC CCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHCCCCCCCCEEEEECCCCCEEEECHHH RNIRGYQKEPEKFMAVEWDQDIEQEFIAEIKVDMFNHQGALANLTAAINAAESNIQSLNT CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC EEKDGRVYSAFIRLTTRDRIHLANIMRKIRIMPDVIKVNRNRN CCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHCHHHHHHCCCCC >Mature Secondary Structure MYLFESLNLLIQRYLPEEQIKRLKQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMR CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHH LDHETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSKLDKLKFQDKKEAQAENFR CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH KMIMAMVQDIRVVLIKLADRTHNMRTLGSLRPDKRRRIARETLEIYSPLAHRLGIHHLKT HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH ELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLTEAGIPCRVSGREKHL HHHHCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHH YSIYLKMHLKEQRFHSIMDIYAFRVIVKEVDTCYRVLGQAHSLYKPRPGRVKDYIAIPKA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCC NGYQSLHTSLIGPHGVPVEVQIRTEDMDQMAEMGVAAHWAYKEKEQGETGTTAQIRAQRW CCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHH MQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVELPAGATPVDFAYAVHTDIG HHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCCCHHHEEECCCCC HACVGARVDRQPYPLSQSLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQMLKNLK HHHHCCCCCCCCCCCCHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC RDDSVGLGRRLLNHALGGSRKLAEVPAENIQHELDRMKLATLDDLLAEIGLGNAMSVVVA CCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEE KNLQGDQSNLGASSGVRNLAIKGSDGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESC CCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHCCCCCCCCEEEEECCCCCEEEECHHH RNIRGYQKEPEKFMAVEWDQDIEQEFIAEIKVDMFNHQGALANLTAAINAAESNIQSLNT CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC EEKDGRVYSAFIRLTTRDRIHLANIMRKIRIMPDVIKVNRNRN CCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHCHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]