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The map label for this gene is cidA [H]

Identifier: 157372661

GI number: 157372661

Start: 4900897

End: 4901319

Strand: Reverse

Name: cidA [H]

Synonym: Spro_4428

Alternate gene names: 157372661

Gene position: 4901319-4900897 (Counterclockwise)

Preceding gene: 157372663

Following gene: 157372660

Centisome position: 89.95

GC content: 57.92

Gene sequence:

>423_bases
ATGTTACTGGCGTTACGCCACGCTGCTCCTTCTTTGCTGACCCGCTTGCAGGTGCCTGTCCAGGTTGTTTTATACGCGGC
GTTATTTTTGATTGCTGACCGGCTGGTGCAGCAGTTCCATTTGCCGTTGCCCGCCAACATTATCGGCATGTTGATGCTGC
TGGCGCTGATTTCGCTGCGCATTCTGCCGCTGAACTGGGTCAGGGCCGGTTCGCGCTGGCTGCTGGCCGAGATGCTGCTG
TTCTTCGTCCCGGCGGTAGTGGCGGTGGTCAACTATGCCCAGTTGCTGATGGTTGAGGGCTGGAAGATTTTCCTGGTGAT
TGCCGTCAGCACCACGCTGACGTTGGCCGCAACGGGGCTGGTGGTCGACCGGGTCTATCGACTGGAAGTCTGGTTACAAC
GGCGAAAACAGCGCGATGAATGA

Upstream 100 bases:

>100_bases
TCCCTGATGGCATGATATTGATAATTTTAATTCATTTCAGGCGGGGTTTCCTGGCTGCGTATACTGTAATCCGTGAATTT
TTTGTTTAAGGTCATCTTCC

Downstream 100 bases:

>100_bases
TTTTATCCTGAGCATCGCCTGCTTTGTGGCAACGCTGGCGCTCTATTTCGCCAATAAAAAACTCTACCGCCGCCGTCGAA
CCTTGCTGTTGATGCCATTG

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MLLALRHAAPSLLTRLQVPVQVVLYAALFLIADRLVQQFHLPLPANIIGMLMLLALISLRILPLNWVRAGSRWLLAEMLL
FFVPAVVAVVNYAQLLMVEGWKIFLVIAVSTTLTLAATGLVVDRVYRLEVWLQRRKQRDE

Sequences:

>Translated_140_residues
MLLALRHAAPSLLTRLQVPVQVVLYAALFLIADRLVQQFHLPLPANIIGMLMLLALISLRILPLNWVRAGSRWLLAEMLL
FFVPAVVAVVNYAQLLMVEGWKIFLVIAVSTTLTLAATGLVVDRVYRLEVWLQRRKQRDE
>Mature_140_residues
MLLALRHAAPSLLTRLQVPVQVVLYAALFLIADRLVQQFHLPLPANIIGMLMLLALISLRILPLNWVRAGSRWLLAEMLL
FFVPAVVAVVNYAQLLMVEGWKIFLVIAVSTTLTLAATGLVVDRVYRLEVWLQRRKQRDE

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 15881; Mature: 15881

Theoretical pI: Translated: 11.30; Mature: 11.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLALRHAAPSLLTRLQVPVQVVLYAALFLIADRLVQQFHLPLPANIIGMLMLLALISLR
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ILPLNWVRAGSRWLLAEMLLFFVPAVVAVVNYAQLLMVEGWKIFLVIAVSTTLTLAATGL
HCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VVDRVYRLEVWLQRRKQRDE
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLALRHAAPSLLTRLQVPVQVVLYAALFLIADRLVQQFHLPLPANIIGMLMLLALISLR
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ILPLNWVRAGSRWLLAEMLLFFVPAVVAVVNYAQLLMVEGWKIFLVIAVSTTLTLAATGL
HCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VVDRVYRLEVWLQRRKQRDE
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA