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The map label for this gene is shlB [H]

Identifier: 157372636

GI number: 157372636

Start: 4871958

End: 4873631

Strand: Reverse

Name: shlB [H]

Synonym: Spro_4403

Alternate gene names: 157372636

Gene position: 4873631-4871958 (Counterclockwise)

Preceding gene: 157372637

Following gene: 157372635

Centisome position: 89.44

GC content: 58.6

Gene sequence:

>1674_bases
ATGGATTCAGTTACTCAACGGCTTTCGGCTGCTTTGCTGTGCATTTTCTTTTCTTCCGCCACCGGCGCTAACCTGCTTAG
CCCGGCGGACCGCGACACGATCCAACAACAGCAGCGCGAATTACTGGAACAAAACCAGCAGCAGCGACAGGAATTGCAAC
GCAGCCTGACGCCGACCTTGCCAGCAACCCCGGCACCCAGCGCCAACGCGGGTGGCCCTTGCTTCACCATCACCCAAATT
CAACTGGAAGGCGCCGAGCATCTGCCTGCCAGCGCGCAACGTAAACTCACCCAGAATTACCTGCAGCAATGCCTGAATCT
GGGGCAAATCCAAACGCTGGTGCAGCAGATCTCCGACTGGTATATCGGCCGTGGCTATATCACCAGCCGCGCATTTCTGA
CCGAGCAGGATCTGTCGCGTGGCGAACTGCGGTTACTGGTGCTGGAAGGCAAGCTGGAGAAAATTCAGTTGGAAAAGCAG
GACGATCGGATGCTGAAAATGGCTTTCCCGGGCCTGCAGGGCAAAATCCTTAACCTGCGTGATATCGAGCAGGGCATGGA
GCAGATCAACCGCCTGCGTCAGCAACCGGTGCAGATAGAAATCCTGCCCGGCAGCCAACCGGGTTACTCAGTGGTCAACC
TGAGCGCCAAACCCGAATTTCCGCTGATGCTCGGGCTGGGTTTCGACAACAGCGGGCAAAAAAGCACCGGGACCGGCCAG
ATCAACGGATCCTTGACCGGCAATAACCTGCTCGGGTTGGCGGACCAATGGTTTGTCGCCGGCGCCCGCAGCAGTGATTT
TGCCAACGATCACAACGCACGCAGCGTACAAACCGGCGTCAGCCTGCCCTACGGCTACTGGACGCTGGATTACAACTATT
CCTACAGCGATTACCTGACCACGCTCAATAACCAGGGTTTTGACTGGCGCTCCAGCGGTGACAGCCAGACCCATCGCCTG
GGCGTTTCGCGGGTGCTGTTCCGTGACGGCGAAATGAAAACAGGCCTGTCGCTGGGGCTGACGCACCGCATCAATCGCAA
TTACCTCAACGATACCCGGCTGGAAAGCAGCAGCCGCAAGCTGACCAGCGTCACGTTGGGGGTCAGCCACAGCCATAAAT
TGCTGGGCGGGTTCGCCACCCTGAACCCGGCCTACAGCCGTGGCGTCCCCTGGCTGGGCGCAGAAAATGACAGCGGAAAA
ATCAAGGAAGCGCCCCGGGCCGAGTTTCACAAGCTTTCGCTTTCCGGCAGCTACTATCTGCCGCTGGCGCAAGATTGGAC
CTATCTCACCAGCCTTTACAGCCAGTGGAGTAACCACCGTTTGTACGGCAGCGAACGCCTGACGATAGGTGGAGAAAGCT
CTGTGCGTGGTTTCAAGGAACAATACCTTTCCGGAGACAAGGGCGGTTACTGGCGTAACGAGGTCAATCGCACGCTGGTG
ACATTGCCGTACCTCGGCAGCATCAACGCCCTGGCGGCGCTCGATGGTGGCTATTTACAGCGTGACAAGCTGGACGCTAA
CGCCTCCGGCACGCTGTGGGGCGGCGCAGTGGGGCTGGGCAGCCGCGGCCGCTATTTCGGCAGCCAACTGACCGTCGGCT
GGCCGCTGGCGTATCCCGATTGGCTCAAACCGGATCGGGTTTCGGTTTACTACCGGGTGAATATCGTACTTTAA

Upstream 100 bases:

>100_bases
ACCAATCGGCCTGAACTACCTCATTGGCTAATGATTCAACCTTGTTACATTCCCCGTCCTGTCGTTAAAATGCTGAAAAA
ACACACGGATGGTCTTCTGA

Downstream 100 bases:

>100_bases
CGCTACTGTACAGGAAGGTTTCAAGGATGAAGCGTAAACAGAATCAACCGCTTAATACCCCTCAGCGTCTGCTGAGCTAC
ACCCTGTGCATGTTACTGGC

Product: polypeptide-transport-associated domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MDSVTQRLSAALLCIFFSSATGANLLSPADRDTIQQQQRELLEQNQQQRQELQRSLTPTLPATPAPSANAGGPCFTITQI
QLEGAEHLPASAQRKLTQNYLQQCLNLGQIQTLVQQISDWYIGRGYITSRAFLTEQDLSRGELRLLVLEGKLEKIQLEKQ
DDRMLKMAFPGLQGKILNLRDIEQGMEQINRLRQQPVQIEILPGSQPGYSVVNLSAKPEFPLMLGLGFDNSGQKSTGTGQ
INGSLTGNNLLGLADQWFVAGARSSDFANDHNARSVQTGVSLPYGYWTLDYNYSYSDYLTTLNNQGFDWRSSGDSQTHRL
GVSRVLFRDGEMKTGLSLGLTHRINRNYLNDTRLESSSRKLTSVTLGVSHSHKLLGGFATLNPAYSRGVPWLGAENDSGK
IKEAPRAEFHKLSLSGSYYLPLAQDWTYLTSLYSQWSNHRLYGSERLTIGGESSVRGFKEQYLSGDKGGYWRNEVNRTLV
TLPYLGSINALAALDGGYLQRDKLDANASGTLWGGAVGLGSRGRYFGSQLTVGWPLAYPDWLKPDRVSVYYRVNIVL

Sequences:

>Translated_557_residues
MDSVTQRLSAALLCIFFSSATGANLLSPADRDTIQQQQRELLEQNQQQRQELQRSLTPTLPATPAPSANAGGPCFTITQI
QLEGAEHLPASAQRKLTQNYLQQCLNLGQIQTLVQQISDWYIGRGYITSRAFLTEQDLSRGELRLLVLEGKLEKIQLEKQ
DDRMLKMAFPGLQGKILNLRDIEQGMEQINRLRQQPVQIEILPGSQPGYSVVNLSAKPEFPLMLGLGFDNSGQKSTGTGQ
INGSLTGNNLLGLADQWFVAGARSSDFANDHNARSVQTGVSLPYGYWTLDYNYSYSDYLTTLNNQGFDWRSSGDSQTHRL
GVSRVLFRDGEMKTGLSLGLTHRINRNYLNDTRLESSSRKLTSVTLGVSHSHKLLGGFATLNPAYSRGVPWLGAENDSGK
IKEAPRAEFHKLSLSGSYYLPLAQDWTYLTSLYSQWSNHRLYGSERLTIGGESSVRGFKEQYLSGDKGGYWRNEVNRTLV
TLPYLGSINALAALDGGYLQRDKLDANASGTLWGGAVGLGSRGRYFGSQLTVGWPLAYPDWLKPDRVSVYYRVNIVL
>Mature_557_residues
MDSVTQRLSAALLCIFFSSATGANLLSPADRDTIQQQQRELLEQNQQQRQELQRSLTPTLPATPAPSANAGGPCFTITQI
QLEGAEHLPASAQRKLTQNYLQQCLNLGQIQTLVQQISDWYIGRGYITSRAFLTEQDLSRGELRLLVLEGKLEKIQLEKQ
DDRMLKMAFPGLQGKILNLRDIEQGMEQINRLRQQPVQIEILPGSQPGYSVVNLSAKPEFPLMLGLGFDNSGQKSTGTGQ
INGSLTGNNLLGLADQWFVAGARSSDFANDHNARSVQTGVSLPYGYWTLDYNYSYSDYLTTLNNQGFDWRSSGDSQTHRL
GVSRVLFRDGEMKTGLSLGLTHRINRNYLNDTRLESSSRKLTSVTLGVSHSHKLLGGFATLNPAYSRGVPWLGAENDSGK
IKEAPRAEFHKLSLSGSYYLPLAQDWTYLTSLYSQWSNHRLYGSERLTIGGESSVRGFKEQYLSGDKGGYWRNEVNRTLV
TLPYLGSINALAALDGGYLQRDKLDANASGTLWGGAVGLGSRGRYFGSQLTVGWPLAYPDWLKPDRVSVYYRVNIVL

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 61840; Mature: 61840

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVTQRLSAALLCIFFSSATGANLLSPADRDTIQQQQRELLEQNQQQRQELQRSLTPTL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PATPAPSANAGGPCFTITQIQLEGAEHLPASAQRKLTQNYLQQCLNLGQIQTLVQQISDW
CCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
YIGRGYITSRAFLTEQDLSRGELRLLVLEGKLEKIQLEKQDDRMLKMAFPGLQGKILNLR
CCCCCEEECCEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCEEEEECCCCCCEEECHH
DIEQGMEQINRLRQQPVQIEILPGSQPGYSVVNLSAKPEFPLMLGLGFDNSGQKSTGTGQ
HHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCE
INGSLTGNNLLGLADQWFVAGARSSDFANDHNARSVQTGVSLPYGYWTLDYNYSYSDYLT
EECEECCCCEECCCCHHEEECCCCCCCCCCCCCCEECCCCCCCCEEEEEEECCCHHHHHH
TLNNQGFDWRSSGDSQTHRLGVSRVLFRDGEMKTGLSLGLTHRINRNYLNDTRLESSSRK
HHCCCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCEECEEECCCCCCCCCHHCCCCCCE
LTSVTLGVSHSHKLLGGFATLNPAYSRGVPWLGAENDSGKIKEAPRAEFHKLSLSGSYYL
EEEEEEECCCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCEEE
PLAQDWTYLTSLYSQWSNHRLYGSERLTIGGESSVRGFKEQYLSGDKGGYWRNEVNRTLV
ECCCCHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHCCCCCCCCHHCCCCEEE
TLPYLGSINALAALDGGYLQRDKLDANASGTLWGGAVGLGSRGRYFGSQLTVGWPLAYPD
EECCCCCCCHHEECCCCCEECCCCCCCCCCCEECCEECCCCCCCCCCCEEEEECCCCCCC
WLKPDRVSVYYRVNIVL
CCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MDSVTQRLSAALLCIFFSSATGANLLSPADRDTIQQQQRELLEQNQQQRQELQRSLTPTL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PATPAPSANAGGPCFTITQIQLEGAEHLPASAQRKLTQNYLQQCLNLGQIQTLVQQISDW
CCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
YIGRGYITSRAFLTEQDLSRGELRLLVLEGKLEKIQLEKQDDRMLKMAFPGLQGKILNLR
CCCCCEEECCEEEECCCCCCCCEEEEEEECCCEEEEECCCCCCEEEEECCCCCCEEECHH
DIEQGMEQINRLRQQPVQIEILPGSQPGYSVVNLSAKPEFPLMLGLGFDNSGQKSTGTGQ
HHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCE
INGSLTGNNLLGLADQWFVAGARSSDFANDHNARSVQTGVSLPYGYWTLDYNYSYSDYLT
EECEECCCCEECCCCHHEEECCCCCCCCCCCCCCEECCCCCCCCEEEEEEECCCHHHHHH
TLNNQGFDWRSSGDSQTHRLGVSRVLFRDGEMKTGLSLGLTHRINRNYLNDTRLESSSRK
HHCCCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCEECEEECCCCCCCCCHHCCCCCCE
LTSVTLGVSHSHKLLGGFATLNPAYSRGVPWLGAENDSGKIKEAPRAEFHKLSLSGSYYL
EEEEEEECCCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCEEE
PLAQDWTYLTSLYSQWSNHRLYGSERLTIGGESSVRGFKEQYLSGDKGGYWRNEVNRTLV
ECCCCHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHCCCCCCCCHHCCCCEEE
TLPYLGSINALAALDGGYLQRDKLDANASGTLWGGAVGLGSRGRYFGSQLTVGWPLAYPD
EECCCCCCCHHEECCCCCEECCCCCCCCCCCEECCEECCCCCCCCCCCEEEEECCCCCCC
WLKPDRVSVYYRVNIVL
CCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]