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The map label for this gene is yqhD [H]

Identifier: 157372448

GI number: 157372448

Start: 4672217

End: 4673380

Strand: Direct

Name: yqhD [H]

Synonym: Spro_4215

Alternate gene names: 157372448

Gene position: 4672217-4673380 (Clockwise)

Preceding gene: 157372446

Following gene: 157372449

Centisome position: 85.75

GC content: 59.45

Gene sequence:

>1164_bases
ATGCAAAACTTTATTCTCCATACCCCAACCAAAATCCTGTTCGGTCAAGACCAAATCGCCGGCCTGGCGCAGCAGATCCC
TGCCGATGCACGCATTCTGATCACCTACGGTGGCGGCAGCGTGAAGAAGAACGGCGTGCTGGATCAGGTTTATTCCGCAC
TGGCGGGTCGTAACGTGCAGGAGTTCTCCGGTATTGAACCTAACCCAACCTACGAAACGCTGATGAAAGCGGTCGAGGTC
GTGCGTGCAGAGAACATCGATTTCCTGCTGGCCGTCGGTGGCGGTTCGGTGGTCGATGGCACCAAGTTCATCGCCGCAGC
GGCCCACTATCAGGCGGATAGCGACCCATGGCATATCCTGAAAACCGTCGGCAGCGAAATCAAAGGCGCTGTGCCGATGG
GTTGCGTGCTGACACTGCCGGCTACCGGTTCTGAATCCAACAGCGGCGCGGTGATCACCCGTAAAAGCAGCGGCGACAAA
CAGCATTTCTTCTCGCCATACGTTCAGCCACTGTTTGCGGTACTGGATCCGGTAGTGACCTATTCGCTGCCACCGCGCCA
GATCGCCAACGGCGTGGTCGATGCCTTTATCCACACCATTGAGCAGTACCTGACCTACCCGGTCGATGCGAAAGTGCAGG
ATCGCTTTGCCGAAGGCCTGCTGCTGACGCTGCTGGAAGATGGCCCGCGTGCGCTGGCCGAGCCGGAAAACTATGCCGTA
CGCGCCAACGTGATGTGGAGCGCCACCATGGCATTGAACGGTCTGATCGGTGCCGGTGTGCCGCAAGACTGGGCAACCCA
TATGCTGGGCCACGAGTTAACCGCCATGCACGGTCTGGATCATGCCCAGACGCTGGCCATCGTCCTGCCGGCGCTGCTGA
ACGAGAAAAAAGCGCAGAAACGCGAAAAACTGCTGCAGTACGCCGACCGCGTCTGGGGTCTGCGTGAGGGCAGCGAAGAC
AGCCGTATCGACGGGGCCATCGCCGCCACCCGTGCCTTCTTCGAACAGATGGGCGTGCCAACCCGCATGGCCGATTACCA
GCTCGACGGCAGCTCGATCCCGGCACTGCTCGATAAGCTGCATCAGCACGGCATGACCGCGCTGGGCGAACATCAGGACA
TCACCCTGGAAGTCAGCCAACGTATTTATGAGGCGGCACGTTAA

Upstream 100 bases:

>100_bases
GGCAGGAATGAGCATTGTGCTGCGGGGCCAGGTTACTGACAATACACCCCAGATATTTTGCGCCATCCGGCGCTTGCCTC
ATGCAGAAGAGAAATCAGCC

Downstream 100 bases:

>100_bases
TCGCAAACTCGCGGTTACCTGTCAGGCTTTAATTTCAGTCTCTTGCGCCCGAGCTGTCCTCGGGCGCAGTGCCAAGCACT
ATTCTGATATCGCTGAAATT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MQNFILHTPTKILFGQDQIAGLAQQIPADARILITYGGGSVKKNGVLDQVYSALAGRNVQEFSGIEPNPTYETLMKAVEV
VRAENIDFLLAVGGGSVVDGTKFIAAAAHYQADSDPWHILKTVGSEIKGAVPMGCVLTLPATGSESNSGAVITRKSSGDK
QHFFSPYVQPLFAVLDPVVTYSLPPRQIANGVVDAFIHTIEQYLTYPVDAKVQDRFAEGLLLTLLEDGPRALAEPENYAV
RANVMWSATMALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALLNEKKAQKREKLLQYADRVWGLREGSED
SRIDGAIAATRAFFEQMGVPTRMADYQLDGSSIPALLDKLHQHGMTALGEHQDITLEVSQRIYEAAR

Sequences:

>Translated_387_residues
MQNFILHTPTKILFGQDQIAGLAQQIPADARILITYGGGSVKKNGVLDQVYSALAGRNVQEFSGIEPNPTYETLMKAVEV
VRAENIDFLLAVGGGSVVDGTKFIAAAAHYQADSDPWHILKTVGSEIKGAVPMGCVLTLPATGSESNSGAVITRKSSGDK
QHFFSPYVQPLFAVLDPVVTYSLPPRQIANGVVDAFIHTIEQYLTYPVDAKVQDRFAEGLLLTLLEDGPRALAEPENYAV
RANVMWSATMALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALLNEKKAQKREKLLQYADRVWGLREGSED
SRIDGAIAATRAFFEQMGVPTRMADYQLDGSSIPALLDKLHQHGMTALGEHQDITLEVSQRIYEAAR
>Mature_387_residues
MQNFILHTPTKILFGQDQIAGLAQQIPADARILITYGGGSVKKNGVLDQVYSALAGRNVQEFSGIEPNPTYETLMKAVEV
VRAENIDFLLAVGGGSVVDGTKFIAAAAHYQADSDPWHILKTVGSEIKGAVPMGCVLTLPATGSESNSGAVITRKSSGDK
QHFFSPYVQPLFAVLDPVVTYSLPPRQIANGVVDAFIHTIEQYLTYPVDAKVQDRFAEGLLLTLLEDGPRALAEPENYAV
RANVMWSATMALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALLNEKKAQKREKLLQYADRVWGLREGSED
SRIDGAIAATRAFFEQMGVPTRMADYQLDGSSIPALLDKLHQHGMTALGEHQDITLEVSQRIYEAAR

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=387, Percent_Identity=77.2609819121447, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=317, Percent_Identity=25.5520504731861, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082107, Length=277, Percent_Identity=26.3537906137184, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789163, Length=331, Percent_Identity=27.190332326284, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787493, Length=348, Percent_Identity=25.2873563218391, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=248, Percent_Identity=25.4032258064516, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24657991, Length=367, Percent_Identity=24.5231607629428, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 41983; Mature: 41983

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNFILHTPTKILFGQDQIAGLAQQIPADARILITYGGGSVKKNGVLDQVYSALAGRNVQ
CCCCEEECCCCEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHH
EFSGIEPNPTYETLMKAVEVVRAENIDFLLAVGGGSVVDGTKFIAAAAHYQADSDPWHIL
HHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCCHHHHH
KTVGSEIKGAVPMGCVLTLPATGSESNSGAVITRKSSGDKQHFFSPYVQPLFAVLDPVVT
HHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
YSLPPRQIANGVVDAFIHTIEQYLTYPVDAKVQDRFAEGLLLTLLEDGPRALAEPENYAV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHEEHHCCCCHHHCCCCCCEE
RANVMWSATMALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALLNEKKAQK
EEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
REKLLQYADRVWGLREGSEDSRIDGAIAATRAFFEQMGVPTRMADYQLDGSSIPALLDKL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEECCCCHHHHHHHH
HQHGMTALGEHQDITLEVSQRIYEAAR
HHCCCHHCCCCCCEEHHHHHHHHHHCC
>Mature Secondary Structure
MQNFILHTPTKILFGQDQIAGLAQQIPADARILITYGGGSVKKNGVLDQVYSALAGRNVQ
CCCCEEECCCCEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHH
EFSGIEPNPTYETLMKAVEVVRAENIDFLLAVGGGSVVDGTKFIAAAAHYQADSDPWHIL
HHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCCHHHHH
KTVGSEIKGAVPMGCVLTLPATGSESNSGAVITRKSSGDKQHFFSPYVQPLFAVLDPVVT
HHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
YSLPPRQIANGVVDAFIHTIEQYLTYPVDAKVQDRFAEGLLLTLLEDGPRALAEPENYAV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHEEHHCCCCHHHCCCCCCEE
RANVMWSATMALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALLNEKKAQK
EEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
REKLLQYADRVWGLREGSEDSRIDGAIAATRAFFEQMGVPTRMADYQLDGSSIPALLDKL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEECCCCHHHHHHHH
HQHGMTALGEHQDITLEVSQRIYEAAR
HHCCCHHCCCCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]