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The map label for this gene is 157372317

Identifier: 157372317

GI number: 157372317

Start: 4538281

End: 4539510

Strand: Direct

Name: 157372317

Synonym: Spro_4083

Alternate gene names: NA

Gene position: 4538281-4539510 (Clockwise)

Preceding gene: 157372316

Following gene: 157372318

Centisome position: 83.29

GC content: 38.13

Gene sequence:

>1230_bases
ATGAGTGTGGATAACAAGGTGCCAGAGATTCGGTTTAAGGGGTTTAGTGAGGCGTGGGTTGATAGTGATCTGAAAAGTTT
TAGTGATTCGTTTAGTTATGGTTTAAACGCTTCTGCAGTTAAATTCGATGGTGTTAATAAGTACCTTAGAATTACAGATA
TCGATGAGAAAAGTAGGAATTTTGACTATTGTCAGTTAACCTCACCAGATGCCGACTTATCAAAATCTGATAATTATTTG
TTAAAGAAAGGTGATATTTTATTTGCTAGAACTGGTGCTAGTGTCGGCAAGACTTATATTTACAACGAGCAAGACGGCAA
AGTCTATTTTGCTGGATTCCTAATTCGAGCAAGCATCAATCATGAAGCAAGTGCGCAGTTTATTTTTCAAAACACGCAAA
CTCATGAGTATGCAAGATTTGTTGCTACTACCTCTCAAAGGTCAGGGCAACCAGGAATAAATGCAAAAGAATATGGTGAA
TACCGACTATTTTCACCTACTGAACCAGAACAAACCCAAATCGGCAACTACTTCCAAAAACTCGACACGCTAATCAATCA
ACACCAACAAAAGCATGACAAGCTCAGCAGCATTAAAAAAGCTATGCTGGAAAAGATGTTTCCCAAACAAGGTGAAACCA
TTCCAGAAATCCGCTTTAAAGGGTTTAGTGGGGAGTGGGAGGAAAAAAGCGTTGGCCAGTTTGGTGAGATTATAACGGGC
TCTACACCGTCGACACAGAACTTAATTAATTATTCTAATGATGGAATACCTTGGGTTACACCAACTGATATTTCGAGAAA
CGTTACATTTAATACAGCTAAAAGGTTATCACAAACAGGCTGTAAAGTAGCTCGCATAGTCCCAAAAGATACAATTTTGG
TTACATGTATCGCCAGCATAGGAAAAAATACAATCCTAGGAACCCAAGGTGGTTTTAACCAGCAAATAAATGGCATTATT
CCAAACCAAAAAGATAACCATCCATATTTTATATTTTCTGCAAGCATATTGTGGTCAGAAAAATTAAAGCGTTCAGCTGC
TTCTGGAACCATGCAAATTGTAAATAAAACTGAGTTTTCCGAATTAAAAACCCGTGCACCAAAAAAAGAAGAACAAACCG
CCATCGGCAACTACTTCCAAAAACTCGACAGTCTGATCGACCAACACCAACAACAGATCACCAAACTCAATAACATCAAG
CAGGCCTGCTTAAGTAAAATGTTTGTCTAA

Upstream 100 bases:

>100_bases
ACCGAGCAAGAACTGGCGGAAATGATGGGTGAACTCACCGGTAATGAGTTTGATATGCAAGGCTTGGTAGAGCTCACTAA
CTTATTGAAGGATGAATAAG

Downstream 100 bases:

>100_bases
CAGGGAGTGCCATCATGACCACCTTTAAAACAGAAGCGCAATTTGAGCAGGCCTTTATTGAGGTTCTCACCAACAAAGGT
TGGGAGCCGGAGATACTCAA

Product: restriction modification system DNA specificity subunit

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSVDNKVPEIRFKGFSEAWVDSDLKSFSDSFSYGLNASAVKFDGVNKYLRITDIDEKSRNFDYCQLTSPDADLSKSDNYL
LKKGDILFARTGASVGKTYIYNEQDGKVYFAGFLIRASINHEASAQFIFQNTQTHEYARFVATTSQRSGQPGINAKEYGE
YRLFSPTEPEQTQIGNYFQKLDTLINQHQQKHDKLSSIKKAMLEKMFPKQGETIPEIRFKGFSGEWEEKSVGQFGEIITG
STPSTQNLINYSNDGIPWVTPTDISRNVTFNTAKRLSQTGCKVARIVPKDTILVTCIASIGKNTILGTQGGFNQQINGII
PNQKDNHPYFIFSASILWSEKLKRSAASGTMQIVNKTEFSELKTRAPKKEEQTAIGNYFQKLDSLIDQHQQQITKLNNIK
QACLSKMFV

Sequences:

>Translated_409_residues
MSVDNKVPEIRFKGFSEAWVDSDLKSFSDSFSYGLNASAVKFDGVNKYLRITDIDEKSRNFDYCQLTSPDADLSKSDNYL
LKKGDILFARTGASVGKTYIYNEQDGKVYFAGFLIRASINHEASAQFIFQNTQTHEYARFVATTSQRSGQPGINAKEYGE
YRLFSPTEPEQTQIGNYFQKLDTLINQHQQKHDKLSSIKKAMLEKMFPKQGETIPEIRFKGFSGEWEEKSVGQFGEIITG
STPSTQNLINYSNDGIPWVTPTDISRNVTFNTAKRLSQTGCKVARIVPKDTILVTCIASIGKNTILGTQGGFNQQINGII
PNQKDNHPYFIFSASILWSEKLKRSAASGTMQIVNKTEFSELKTRAPKKEEQTAIGNYFQKLDSLIDQHQQQITKLNNIK
QACLSKMFV
>Mature_408_residues
SVDNKVPEIRFKGFSEAWVDSDLKSFSDSFSYGLNASAVKFDGVNKYLRITDIDEKSRNFDYCQLTSPDADLSKSDNYLL
KKGDILFARTGASVGKTYIYNEQDGKVYFAGFLIRASINHEASAQFIFQNTQTHEYARFVATTSQRSGQPGINAKEYGEY
RLFSPTEPEQTQIGNYFQKLDTLINQHQQKHDKLSSIKKAMLEKMFPKQGETIPEIRFKGFSGEWEEKSVGQFGEIITGS
TPSTQNLINYSNDGIPWVTPTDISRNVTFNTAKRLSQTGCKVARIVPKDTILVTCIASIGKNTILGTQGGFNQQINGIIP
NQKDNHPYFIFSASILWSEKLKRSAASGTMQIVNKTEFSELKTRAPKKEEQTAIGNYFQKLDSLIDQHQQQITKLNNIKQ
ACLSKMFV

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 46109; Mature: 45978

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDNKVPEIRFKGFSEAWVDSDLKSFSDSFSYGLNASAVKFDGVNKYLRITDIDEKSRN
CCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCC
FDYCQLTSPDADLSKSDNYLLKKGDILFARTGASVGKTYIYNEQDGKVYFAGFLIRASIN
CCEEEECCCCCCCCCCCCEEEECCCEEEEECCCCCCCEEEEECCCCCEEEEEEEEEEECC
HEASAQFIFQNTQTHEYARFVATTSQRSGQPGINAKEYGEYRLFSPTEPEQTQIGNYFQK
CCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEECCCCCCHHHHHHHHHHH
LDTLINQHQQKHDKLSSIKKAMLEKMFPKQGETIPEIRFKGFSGEWEEKSVGQFGEIITG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCC
STPSTQNLINYSNDGIPWVTPTDISRNVTFNTAKRLSQTGCKVARIVPKDTILVTCIASI
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHC
GKNTILGTQGGFNQQINGIIPNQKDNHPYFIFSASILWSEKLKRSAASGTMQIVNKTEFS
CCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
ELKTRAPKKEEQTAIGNYFQKLDSLIDQHQQQITKLNNIKQACLSKMFV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVDNKVPEIRFKGFSEAWVDSDLKSFSDSFSYGLNASAVKFDGVNKYLRITDIDEKSRN
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCC
FDYCQLTSPDADLSKSDNYLLKKGDILFARTGASVGKTYIYNEQDGKVYFAGFLIRASIN
CCEEEECCCCCCCCCCCCEEEECCCEEEEECCCCCCCEEEEECCCCCEEEEEEEEEEECC
HEASAQFIFQNTQTHEYARFVATTSQRSGQPGINAKEYGEYRLFSPTEPEQTQIGNYFQK
CCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEECCCCCCHHHHHHHHHHH
LDTLINQHQQKHDKLSSIKKAMLEKMFPKQGETIPEIRFKGFSGEWEEKSVGQFGEIITG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCC
STPSTQNLINYSNDGIPWVTPTDISRNVTFNTAKRLSQTGCKVARIVPKDTILVTCIASI
CCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHC
GKNTILGTQGGFNQQINGIIPNQKDNHPYFIFSASILWSEKLKRSAASGTMQIVNKTEFS
CCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
ELKTRAPKKEEQTAIGNYFQKLDSLIDQHQQQITKLNNIKQACLSKMFV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]