BacMap

Definition	Serratia proteamaculans 568 chromosome, complete genome.
Accession	NC_009832
Length	5,448,853

Click here to switch to the map view.

The map label for this gene is pldh-t [H]

Identifier: 157372200

GI number: 157372200

Start: 4394951

End: 4395706

Strand: Reverse

Name: pldh-t [H]

Synonym: Spro_3966

Alternate gene names: 157372200

Gene position: 4395706-4394951 (Counterclockwise)

Preceding gene: 157372201

Following gene: 157372199

Centisome position: 80.67

GC content: 63.49

Gene sequence:

>756_bases
GTGAACGGCCTGCTGACGGGGAAACGTATTGTGGTGACTGGCGCGGCACGCGGGCTGGGGCGTAGTTTCGCCGCCGCTAT
TGCCGCCGCCGGTGCCAAGGTGGTGATGTGCGATATTCTGGCGGATGAATTGGCAGACGCTGCCGTCAGCCTGCGCGAGC
AGGGGGCTCAGGTCGAAAGCCAGGTTATCGATCTGGCCGATCCTGCCTCGATCAGCGCCGCGTTTAACGCCATCGCCGCA
GGCGGAGCGATCGACGGGTTGGTGAACAATGCGGCCCTGGCCACCGGCGTCGGCGGCAAAACCATGATGGAATACGACAT
CGATCTGTGGGATCGGGTGATGCAGGTTAACGTACGCGGCACCTGGCTGGTGAGCCAGGCGGCGGTACCGCTGCTGGCTC
AAACCCCGCATGCCAAGATCGTTAACGTGGCTTCGGATACCGCGCTGTGGGGCGCTCCGCGCTTAATGGCCTATGTGGCC
AGCAAAGGGGCGATTATCTCGATGACCCGCTCGATGGCGCGTGAGCTGGGCCCGCAGGGCATTTGCGTCAATGCCATCGC
ACCGGGCCTGACGCGGGTGGAGGCCACGGAATACGTGCCTGCCGAGCGTCACCAATTGTACGAGCAGGGCCGGGCCTTGG
CCGGGGCGCAGCATCCTGACGACGTCAACGGCACGGTGCTCTATCTGCTGTCACCGTTGGCGAACTTCGTGACCGGTCAG
TTGTTGCCGGTTAACGGCGGCTTCGTCTTTAACTAA

Upstream 100 bases:

>100_bases
ATCTGTACCAGCATGACGTCGGGCTATCTCGCCTGCGCCGCATGATGCAAAAAGAGGCGCAGAAACAGCTGGCGCGGCTC
AGTGAACTGGAGGCGGCGCA

Downstream 100 bases:

>100_bases
TCAATATTCAATTAGCCAGGAGCAGCACATGGCAGACGACCAAGGGTGTAAATATCTGATCCCAGGACTGGATCGCGGAT
TGCAACTGTTGCTGGCGTTT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: tPLDH [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNGLLTGKRIVVTGAARGLGRSFAAAIAAAGAKVVMCDILADELADAAVSLREQGAQVESQVIDLADPASISAAFNAIAA
GGAIDGLVNNAALATGVGGKTMMEYDIDLWDRVMQVNVRGTWLVSQAAVPLLAQTPHAKIVNVASDTALWGAPRLMAYVA
SKGAIISMTRSMARELGPQGICVNAIAPGLTRVEATEYVPAERHQLYEQGRALAGAQHPDDVNGTVLYLLSPLANFVTGQ
LLPVNGGFVFN

Sequences:

>Translated_251_residues
MNGLLTGKRIVVTGAARGLGRSFAAAIAAAGAKVVMCDILADELADAAVSLREQGAQVESQVIDLADPASISAAFNAIAA
GGAIDGLVNNAALATGVGGKTMMEYDIDLWDRVMQVNVRGTWLVSQAAVPLLAQTPHAKIVNVASDTALWGAPRLMAYVA
SKGAIISMTRSMARELGPQGICVNAIAPGLTRVEATEYVPAERHQLYEQGRALAGAQHPDDVNGTVLYLLSPLANFVTGQ
LLPVNGGFVFN
>Mature_251_residues
MNGLLTGKRIVVTGAARGLGRSFAAAIAAAGAKVVMCDILADELADAAVSLREQGAQVESQVIDLADPASISAAFNAIAA
GGAIDGLVNNAALATGVGGKTMMEYDIDLWDRVMQVNVRGTWLVSQAAVPLLAQTPHAKIVNVASDTALWGAPRLMAYVA
SKGAIISMTRSMARELGPQGICVNAIAPGLTRVEATEYVPAERHQLYEQGRALAGAQHPDDVNGTVLYLLSPLANFVTGQ
LLPVNGGFVFN

Specific function: Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Oxidizes pyridoxal to 4-pyridoxolactone, but does not have activity toward pyridoxal 5'-phosphate, pyridoxine, pyridoxamine, pyridoxamine 5'-phosphat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=32.6693227091633, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=29.0322580645161, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI142976729, Length=212, Percent_Identity=28.3018867924528, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=26.7441860465116, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=26.2948207171315, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=27.9166666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI210032110, Length=203, Percent_Identity=26.1083743842365, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=27.1653543307087, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40254986, Length=197, Percent_Identity=31.4720812182741, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31542939, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=31.3829787234043, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=27.979274611399, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=28.3842794759825, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI186928839, Length=212, Percent_Identity=30.188679245283, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=33.0708661417323, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=34.5381526104418, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=31.0077519379845, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=31.7647058823529, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=30.4347826086957, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=33.1983805668016, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=30.1960784313725, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=28.90625, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=30.2040816326531, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=34.5360824742268, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.5625, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=31.0756972111554, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=32.5396825396825, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=29.8804780876494, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=30.2681992337165, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=27.9693486590038, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=24.2914979757085, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=29.3436293436293, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=28.957528957529, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.2258064516129, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=30.2564102564103, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=210, Percent_Identity=33.8095238095238, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.2134831460674, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=26.6409266409266, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=29.8449612403101, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=174, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=27.4809160305344, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=197, Percent_Identity=27.9187817258883, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71997099, Length=203, Percent_Identity=30.5418719211823, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=196, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=25.1908396946565, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=27.8195488721804, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=173, Percent_Identity=28.3236994219653, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=173, Percent_Identity=26.5895953757225, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=192, Percent_Identity=32.2916666666667, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=171, Percent_Identity=26.9005847953216, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=210, Percent_Identity=29.0476190476191, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=25.3731343283582, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=27.6515151515151, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=30.6532663316583, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.2030651340996, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=26.3358778625954, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=25.3787878787879, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=258, Percent_Identity=27.1317829457364, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=247, Percent_Identity=28.7449392712551, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=32.2834645669291, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=32.9365079365079, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=31.8725099601594, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644337, Length=173, Percent_Identity=37.5722543352601, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=30.7086614173228, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=29.9492385786802, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=32.1285140562249, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737361, Length=192, Percent_Identity=35.4166666666667, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=28.2722513089005, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584752, Length=194, Percent_Identity=28.8659793814433, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.107 [H]

Molecular weight: Translated: 25993; Mature: 25993

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLLTGKRIVVTGAARGLGRSFAAAIAAAGAKVVMCDILADELADAAVSLREQGAQVES
CCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHH
QVIDLADPASISAAFNAIAAGGAIDGLVNNAALATGVGGKTMMEYDIDLWDRVMQVNVRG
HHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHEECCCCCEEEEECHHHHHHHHEECCCC
TWLVSQAAVPLLAQTPHAKIVNVASDTALWGAPRLMAYVASKGAIISMTRSMARELGPQG
EEEEHHHCCCHHCCCCCCEEEEECCCCCHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC
ICVNAIAPGLTRVEATEYVPAERHQLYEQGRALAGAQHPDDVNGTVLYLLSPLANFVTGQ
EEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
LLPVNGGFVFN
EEECCCCEEEC
>Mature Secondary Structure
MNGLLTGKRIVVTGAARGLGRSFAAAIAAAGAKVVMCDILADELADAAVSLREQGAQVES
CCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHH
QVIDLADPASISAAFNAIAAGGAIDGLVNNAALATGVGGKTMMEYDIDLWDRVMQVNVRG
HHHCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHEECCCCCEEEEECHHHHHHHHEECCCC
TWLVSQAAVPLLAQTPHAKIVNVASDTALWGAPRLMAYVASKGAIISMTRSMARELGPQG
EEEEHHHCCCHHCCCCCCEEEEECCCCCHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCC
ICVNAIAPGLTRVEATEYVPAERHQLYEQGRALAGAQHPDDVNGTVLYLLSPLANFVTGQ
EEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
LLPVNGGFVFN
EEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]