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The map label for this gene is nadX

Identifier: 157372192

GI number: 157372192

Start: 4387604

End: 4388398

Strand: Reverse

Name: nadX

Synonym: Spro_3958

Alternate gene names: 157372192

Gene position: 4388398-4387604 (Counterclockwise)

Preceding gene: 157372193

Following gene: 157372191

Centisome position: 80.54

GC content: 64.03

Gene sequence:

>795_bases
ATGAAGAAGATCATGATGATTGGCTACGGCGCAATGGCCAGAGAAGTGCTTTCCCGCTTGCCGGACGGGGTGAGTGTGGG
CTGGATCCTGGCGCGTGCGGCTCATCATGCGGCAATCGACAGTGCCTTCGGTGGCCAGGTGCAGGCGTTAACCCACCCGG
ATCAGTGTACTGAACAGCCGGATCTGGTGCTGGAATGTGCCAGCCAGCAGGCGGTGGCGGAATTTGGTGAAGCGGTGGTG
ACGCGCGGCTGGCCGTTGGCGGTGATCTCCACCGGGGCGCTGGCGGATGCGGCGCTGCAGCAGCGGTTGCAGCAGGCCTG
TCGGCAGCACCAGGGCCAGTTGATCGTCCTGTCCGGAGCGGTGGCGGGGATGGATGGGCTGGCATCGGCGCGTGAAGGCG
GGCTGGACAGCGTCACCTATCAGGCCTGTAAAAGCCCGGCGAGCTGGCGCGGCAGCATGGCGGAGCAATTGATTGATCTT
GATGCCGTGAGCGAGGCGCAGGTGTTTTTTGAAGGTTCGGCGCGTGAGGCGGCGCGGCTGTTCCCGGCCAATGCCAACGT
GGCCGCGACCATTGCGCTTAACGGATTGGGGATGGACGCCACCCGGGTGCGGCTACTGGTCGATCCCGCCACCCGGCGCA
ATACCCACCGGCTACAGGTGTGCGGCAATTTCGGTGAGTTTCAGATTGAGCTGAGCGGCAACCCGCTGGCGAGCAATCCC
AAAACATCAACCCTGGCGGCGCTGAGCGCGGTACAAGCCTGCCGCCGTCTGGTTGACGGTGGCTTTATTGCCTGA

Upstream 100 bases:

>100_bases
TGTTGTTCCTGGCTTCGCCTTTGGCGTCTTTCACTACCGGTGCGGCGCTTGACGTCTCCGGTGGCTTTAACCGCCATCTT
TAACCGCAGGGGCTGAAAAG

Downstream 100 bases:

>100_bases
ACGGCAGGAGCGAGCATGGAAAAGTTAAAGATTTTTGTAGCTGGGCGCTGGTGTGAAGGGCGTGGCGACGAGATGACCTC
GGTGTTTCCGGCCGATGGCA

Product: L-aspartate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKKIMMIGYGAMAREVLSRLPDGVSVGWILARAAHHAAIDSAFGGQVQALTHPDQCTEQPDLVLECASQQAVAEFGEAVV
TRGWPLAVISTGALADAALQQRLQQACRQHQGQLIVLSGAVAGMDGLASAREGGLDSVTYQACKSPASWRGSMAEQLIDL
DAVSEAQVFFEGSAREAARLFPANANVAATIALNGLGMDATRVRLLVDPATRRNTHRLQVCGNFGEFQIELSGNPLASNP
KTSTLAALSAVQACRRLVDGGFIA

Sequences:

>Translated_264_residues
MKKIMMIGYGAMAREVLSRLPDGVSVGWILARAAHHAAIDSAFGGQVQALTHPDQCTEQPDLVLECASQQAVAEFGEAVV
TRGWPLAVISTGALADAALQQRLQQACRQHQGQLIVLSGAVAGMDGLASAREGGLDSVTYQACKSPASWRGSMAEQLIDL
DAVSEAQVFFEGSAREAARLFPANANVAATIALNGLGMDATRVRLLVDPATRRNTHRLQVCGNFGEFQIELSGNPLASNP
KTSTLAALSAVQACRRLVDGGFIA
>Mature_264_residues
MKKIMMIGYGAMAREVLSRLPDGVSVGWILARAAHHAAIDSAFGGQVQALTHPDQCTEQPDLVLECASQQAVAEFGEAVV
TRGWPLAVISTGALADAALQQRLQQACRQHQGQLIVLSGAVAGMDGLASAREGGLDSVTYQACKSPASWRGSMAEQLIDL
DAVSEAQVFFEGSAREAARLFPANANVAATIALNGLGMDATRVRLLVDPATRRNTHRLQVCGNFGEFQIELSGNPLASNP
KTSTLAALSAVQACRRLVDGGFIA

Specific function: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate

COG id: COG1712

COG function: function code R; Predicted dinucleotide-utilizing enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-aspartate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPD_SERP5 (A8GIW3)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480181.1
- ProteinModelPortal:   A8GIW3
- SMR:   A8GIW3
- STRING:   A8GIW3
- GeneID:   5603713
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3958
- eggNOG:   COG1712
- HOGENOM:   HBG649642
- OMA:   ECAGHSA
- ProtClustDB:   PRK13303
- BioCyc:   SPRO399741:SPRO_3958-MONOMER
- HAMAP:   MF_01265
- InterPro:   IPR005106
- InterPro:   IPR002811
- InterPro:   IPR011182
- InterPro:   IPR020626
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF005227

Pfam domain/function: PF01958 DUF108; PF03447 NAD_binding_3

EC number: =1.4.1.21

Molecular weight: Translated: 27768; Mature: 27768

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: ACT_SITE 216-216 BINDING 120-120 BINDING 186-186

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIMMIGYGAMAREVLSRLPDGVSVGWILARAAHHAAIDSAFGGQVQALTHPDQCTEQP
CCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCC
DLVLECASQQAVAEFGEAVVTRGWPLAVISTGALADAALQQRLQQACRQHQGQLIVLSGA
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECC
VAGMDGLASAREGGLDSVTYQACKSPASWRGSMAEQLIDLDAVSEAQVFFEGSAREAARL
HHCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
FPANANVAATIALNGLGMDATRVRLLVDPATRRNTHRLQVCGNFGEFQIELSGNPLASNP
CCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
KTSTLAALSAVQACRRLVDGGFIA
CHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKIMMIGYGAMAREVLSRLPDGVSVGWILARAAHHAAIDSAFGGQVQALTHPDQCTEQP
CCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCC
DLVLECASQQAVAEFGEAVVTRGWPLAVISTGALADAALQQRLQQACRQHQGQLIVLSGA
CHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECC
VAGMDGLASAREGGLDSVTYQACKSPASWRGSMAEQLIDLDAVSEAQVFFEGSAREAARL
HHCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
FPANANVAATIALNGLGMDATRVRLLVDPATRRNTHRLQVCGNFGEFQIELSGNPLASNP
CCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCC
KTSTLAALSAVQACRRLVDGGFIA
CHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA