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The map label for this gene is ttuB [H]

Identifier: 157372169

GI number: 157372169

Start: 4359171

End: 4360466

Strand: Direct

Name: ttuB [H]

Synonym: Spro_3935

Alternate gene names: 157372169

Gene position: 4359171-4360466 (Clockwise)

Preceding gene: 157372168

Following gene: 157372170

Centisome position: 80.0

GC content: 58.41

Gene sequence:

>1296_bases
ATGAATATTGCCTCTGTTTCTGTCACTCAAAACCAGGCGATCCCCAAATTACGCTGGCTGCGGATCGTGCCGCCGATCCT
GATTACCTGCATCATTTCCTATATGGACCGGGTGAATATCGCCTTCGCCATGCCCGGTGGTATGGATGCCGAGCTGGGTA
TTACCGCCTCGATGGCCGGTTTGGCCGGCGGCATCTTCTTTATCGGTTATCTGTTCCTGCAGGTGCCCGGCGGCAAGTTG
GCGGTGTACGGCAACGGCAAGAAATTCATCGGTTGGTCGCTGCTGGCCTGGGCAATTATTTCGGTGCTGACCGGGCTGGT
CAGTAACCAGTATCAACTGTTGTTCCTGCGCTTTGCCCTGGGCGTCTCCGAGGGCGGCATGCTGCCGGTGGTGCTGACCA
TGATCAGCAACTGGTTCCCGGACAAGGAACGCGGCCGTGCCAACGCCATCGTCATTATGTTCGTGCCGATCGCCGGTATT
CTCACCGCCCCGCTGTCCGGCTGGATCATCACCGTCTGGGACTGGCGTATGCTGTTTCTGGTGGAAGGCGCGCTGTCGCT
GGTGGTGATGGTGCTGTGGTACTTCACCATCAGCAACCGTCCGCAGGAGGCCAAGTGGATTTCAGCAGCGGAAAAAGACT
ACCTGATCAAAACGCTGCATGACGAACAACTGCTGATCAAAGGCAAAACGGTGCGCAACGCCTCGCTGCGCCGGGTGTTG
GGCGACAAGATCATGTGGCAGCTGATCCTGGTGAACTTCTTCTACCAGACCGGGATTTACGGCTACACCCTGTGGCTGCC
GACCATCCTCAAGGGGCTGACCAACGGCAACATGGAACAGGTCGGCATACTGGCTATTCTGCCCTACATCGGTGCCATCT
TCGGCATGCTGGTGATTTCCTCACTCTCCGATCGTACCGGAAAACGCAAAATCTTCGTCGCGCTGCCACTGGCCTGCTTC
GCCATCTGCATGGCGCTGTCGGTACTGTTGAAAGATCACATCTGGTGGTCCTACGCCGCGCTGGTCGGCTGCGGGGTATT
CATCCAGGCCGCCGCCGGGGTGTTCTGGACCATTCCTCCCAAACTGTTCAATGCCGAAGTGGCCGGTGGGGCACGCGGCG
TGATCAACGCGCTGGGCAACCTGGGCGGTTTCTGCGGCCCTTATATGGTCGGCGTATTGATCAGCCTGTTCAGCAAGGAC
GTCGGCGTTTACAGCCTGGCGGTATCACTGGCCATTGCCTCGGTGCTGGCGCTGATGCTGCCGAACAAATGCGACCAAAG
CGCGAGGGCCGAATAA

Upstream 100 bases:

>100_bases
AAAGGAATCAAAGATAAAAATCATCGGCCTACGGGCGGGTGTGGGCGCCCCTGCGCCTTAAACCACCAAAACAATAAAAT
CTGACCCTACAGGTGTATAT

Downstream 100 bases:

>100_bases
TGGACTATTGGTTGGGGCTGGACTGCGGTGGCACCTTTATCAAAGCCGGGCTGTATGACCGTCAGGGGGCTGAGCTGAGC
ATCGCTCGCCGCAACCTGGA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MNIASVSVTQNQAIPKLRWLRIVPPILITCIISYMDRVNIAFAMPGGMDAELGITASMAGLAGGIFFIGYLFLQVPGGKL
AVYGNGKKFIGWSLLAWAIISVLTGLVSNQYQLLFLRFALGVSEGGMLPVVLTMISNWFPDKERGRANAIVIMFVPIAGI
LTAPLSGWIITVWDWRMLFLVEGALSLVVMVLWYFTISNRPQEAKWISAAEKDYLIKTLHDEQLLIKGKTVRNASLRRVL
GDKIMWQLILVNFFYQTGIYGYTLWLPTILKGLTNGNMEQVGILAILPYIGAIFGMLVISSLSDRTGKRKIFVALPLACF
AICMALSVLLKDHIWWSYAALVGCGVFIQAAAGVFWTIPPKLFNAEVAGGARGVINALGNLGGFCGPYMVGVLISLFSKD
VGVYSLAVSLAIASVLALMLPNKCDQSARAE

Sequences:

>Translated_431_residues
MNIASVSVTQNQAIPKLRWLRIVPPILITCIISYMDRVNIAFAMPGGMDAELGITASMAGLAGGIFFIGYLFLQVPGGKL
AVYGNGKKFIGWSLLAWAIISVLTGLVSNQYQLLFLRFALGVSEGGMLPVVLTMISNWFPDKERGRANAIVIMFVPIAGI
LTAPLSGWIITVWDWRMLFLVEGALSLVVMVLWYFTISNRPQEAKWISAAEKDYLIKTLHDEQLLIKGKTVRNASLRRVL
GDKIMWQLILVNFFYQTGIYGYTLWLPTILKGLTNGNMEQVGILAILPYIGAIFGMLVISSLSDRTGKRKIFVALPLACF
AICMALSVLLKDHIWWSYAALVGCGVFIQAAAGVFWTIPPKLFNAEVAGGARGVINALGNLGGFCGPYMVGVLISLFSKD
VGVYSLAVSLAIASVLALMLPNKCDQSARAE
>Mature_431_residues
MNIASVSVTQNQAIPKLRWLRIVPPILITCIISYMDRVNIAFAMPGGMDAELGITASMAGLAGGIFFIGYLFLQVPGGKL
AVYGNGKKFIGWSLLAWAIISVLTGLVSNQYQLLFLRFALGVSEGGMLPVVLTMISNWFPDKERGRANAIVIMFVPIAGI
LTAPLSGWIITVWDWRMLFLVEGALSLVVMVLWYFTISNRPQEAKWISAAEKDYLIKTLHDEQLLIKGKTVRNASLRRVL
GDKIMWQLILVNFFYQTGIYGYTLWLPTILKGLTNGNMEQVGILAILPYIGAIFGMLVISSLSDRTGKRKIFVALPLACF
AICMALSVLLKDHIWWSYAALVGCGVFIQAAAGVFWTIPPKLFNAEVAGGARGVINALGNLGGFCGPYMVGVLISLFSKD
VGVYSLAVSLAIASVLALMLPNKCDQSARAE

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=340, Percent_Identity=26.4705882352941, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI148743791, Length=329, Percent_Identity=25.2279635258359, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI9945322, Length=383, Percent_Identity=21.1488250652742, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI9966811, Length=389, Percent_Identity=21.0796915167095, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI148728191, Length=251, Percent_Identity=25.0996015936255, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=28.4009546539379, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789515, Length=406, Percent_Identity=24.8768472906404, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI87082320, Length=401, Percent_Identity=25.9351620947631, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI2367379, Length=279, Percent_Identity=25.4480286738351, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1789152, Length=390, Percent_Identity=22.8205128205128, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI2367193, Length=290, Percent_Identity=26.8965517241379, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17552542, Length=373, Percent_Identity=23.5924932975871, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533556, Length=340, Percent_Identity=25.8823529411765, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI115533554, Length=260, Percent_Identity=27.6923076923077, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560030, Length=349, Percent_Identity=22.0630372492837, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=264, Percent_Identity=22.3484848484848, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540458, Length=223, Percent_Identity=23.7668161434978, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=255, Percent_Identity=22.7450980392157, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=255, Percent_Identity=23.1372549019608, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=255, Percent_Identity=23.1372549019608, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25141316, Length=255, Percent_Identity=23.1372549019608, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71997452, Length=259, Percent_Identity=22.3938223938224, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193205400, Length=206, Percent_Identity=22.3300970873786, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322973, Length=253, Percent_Identity=22.5296442687747, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321698, Length=372, Percent_Identity=20.6989247311828, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641682, Length=391, Percent_Identity=24.2966751918159, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583789, Length=357, Percent_Identity=24.9299719887955, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20130167, Length=308, Percent_Identity=23.7012987012987, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20129235, Length=357, Percent_Identity=25.4901960784314, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584153, Length=407, Percent_Identity=21.8673218673219, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24648416, Length=359, Percent_Identity=23.6768802228412, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356189, Length=359, Percent_Identity=23.6768802228412, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573708, Length=232, Percent_Identity=26.7241379310345, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573707, Length=232, Percent_Identity=26.7241379310345, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654215, Length=376, Percent_Identity=24.2021276595745, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19922400, Length=376, Percent_Identity=24.2021276595745, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24580790, Length=268, Percent_Identity=24.6268656716418, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI20130135, Length=311, Percent_Identity=26.3665594855305, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573299, Length=391, Percent_Identity=24.8081841432225, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24655271, Length=311, Percent_Identity=26.3665594855305, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221474708, Length=399, Percent_Identity=22.0551378446115, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639764, Length=363, Percent_Identity=23.6914600550964, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45550460, Length=299, Percent_Identity=22.0735785953177, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24653727, Length=371, Percent_Identity=23.989218328841, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655255, Length=296, Percent_Identity=21.9594594594595, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46999; Mature: 46999

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIASVSVTQNQAIPKLRWLRIVPPILITCIISYMDRVNIAFAMPGGMDAELGITASMAG
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHH
LAGGIFFIGYLFLQVPGGKLAVYGNGKKFIGWSLLAWAIISVLTGLVSNQYQLLFLRFAL
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GVSEGGMLPVVLTMISNWFPDKERGRANAIVIMFVPIAGILTAPLSGWIITVWDWRMLFL
CCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEHHHHHHHH
VEGALSLVVMVLWYFTISNRPQEAKWISAAEKDYLIKTLHDEQLLIKGKTVRNASLRRVL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHH
GDKIMWQLILVNFFYQTGIYGYTLWLPTILKGLTNGNMEQVGILAILPYIGAIFGMLVIS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLSDRTGKRKIFVALPLACFAICMALSVLLKDHIWWSYAALVGCGVFIQAAAGVFWTIPP
HHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCH
KLFNAEVAGGARGVINALGNLGGFCGPYMVGVLISLFSKDVGVYSLAVSLAIASVLALML
HHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
PNKCDQSARAE
CCCCCCCCCCC
>Mature Secondary Structure
MNIASVSVTQNQAIPKLRWLRIVPPILITCIISYMDRVNIAFAMPGGMDAELGITASMAG
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHH
LAGGIFFIGYLFLQVPGGKLAVYGNGKKFIGWSLLAWAIISVLTGLVSNQYQLLFLRFAL
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GVSEGGMLPVVLTMISNWFPDKERGRANAIVIMFVPIAGILTAPLSGWIITVWDWRMLFL
CCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEHHHHHHHH
VEGALSLVVMVLWYFTISNRPQEAKWISAAEKDYLIKTLHDEQLLIKGKTVRNASLRRVL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHH
GDKIMWQLILVNFFYQTGIYGYTLWLPTILKGLTNGNMEQVGILAILPYIGAIFGMLVIS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLSDRTGKRKIFVALPLACFAICMALSVLLKDHIWWSYAALVGCGVFIQAAAGVFWTIPP
HHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCH
KLFNAEVAGGARGVINALGNLGGFCGPYMVGVLISLFSKDVGVYSLAVSLAIASVLALML
HHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
PNKCDQSARAE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]