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The map label for this gene is rssA [H]

Identifier: 157372145

GI number: 157372145

Start: 4329220

End: 4330626

Strand: Direct

Name: rssA [H]

Synonym: Spro_3911

Alternate gene names: 157372145

Gene position: 4329220-4330626 (Clockwise)

Preceding gene: 157372144

Following gene: 157372155

Centisome position: 79.45

GC content: 50.25

Gene sequence:

>1407_bases
ATGATAAGTTTTAAATCCTTTTTTATGCGCACCATTATTTTCCAGGTTTTAGCTATATTATTGCTCTGGGGCGCATTGAT
TGGTTGGGTAAAATATTCATATTATCCCGATGCGGAAAAGTATTTAGATAATCAGCAACGCATTGTCGCCCGGGGTATCG
CCAATATTCTTGATAAGACAGATGTTACCAACCGCAGTTATCTTGAGGTGATTAAAGATATCGAAGTCATGTATATCGAC
TCGATCAAAAACGGCATGCAGGATGAAATAGACTATCGCCCGCTATTTGTGGTTTACGATAGCAACAACCAAATGCTTTA
CGCCTCACCGTCACAGGAAAAACCGCTGTTCCTGCCGCCGTCGGTGCTGTCCGGCACCATCAGCTACGCCAATGTGAAGT
GGCATATTGCCGGCAGTTGGAGCGATAAACAGCAATTTAGAGTGATCGTCGGCGAATCCTTTGACAACCGCACCACTATT
TTCGGCAATCCGGCGGAAAGCACCGCGATCCCGCTGTTGGTCACCCTGGCAGCCATCATTGTCACTTTGCTGTTTACCGC
CTATCTCAGCCTGCGGCCTCTGCGGCAAATTGCCAGAATGATCTCTGACCGCAAGCCCGGTACTCTGTCGCCGATCAATG
CGGCCGAACAATATCAAGAAATCCGACCAATCGTTTTGGAAATCAACAAGCTGATGGCGCGCATCGATGCAGCCAATCAA
CGTGAAAAGCGCTTTATGGCCGATGCGGCGCATGAGCTGCGCACCCCGATCGCAGCCGTACTGGCACAGCTGCACCTGTT
GACCCAGGTGGCGGATAAAACCGAACGTCAGGAAATCATTGAAGACATGCAGCAAGGGTTGGATCGCGCCGCATCGCTTT
CGCGCCAACTGATTGATCTGGCCAAACTGGAGTCGGAAGACTTCCCACTGAAGATTGAAACGGTGAATATCCACGCGGAA
ATCGGCAAATGCATTGCCCAGCACGTGCCCTATGCGCTGGAGAAGAACGTCGAACTCTCGCTGGATGGCAGTGAAAATGT
GATGATTGATACCGATCGTCACTCGCTGATTACCATTTTTACCAACCTGTTGGAAAACGCCATCAAATACGCGCCTGACG
GTGGCCGAATCGAAGTCAACATCCGTTCGCTATCGCCACTGGGTTGCTATATTACTGTGCGAGACAATGGCCCCGGTATT
AACCCTGAATACCACAAACGGTTATTCGAACGTTTTTATCGCGTGCCAGGTACTCTGCAGGTCGGCAGCGGTCTGGGGCT
GGCGATTGCCAAAAATCTGGCGGATAAAATCGGTGCGCAACTGCGGGTGGCCGAAGGGCTTGATGAACGCGGCATCGGGT
TTGTTATTGATCTACCGGAGAACTATCTGGTGTCATCGGAGAGTTAA

Upstream 100 bases:

>100_bases
CTCTGGAGGTGCATATGCATAACTTGCGGCGCAAGATTGGCAAGGAAAAAATTATCACCGTGCGTGGCATCGGTTATTTA
TTAAAAAAAGAGACTCTGGG

Downstream 100 bases:

>100_bases
GCCAACATCGCCCAGCCAATTTTACTGCAACGGCATCCGCTTGATTTGCTGTGGCAAACAAATGGGCAAACTGCGGTTTG
CCCATAAATATAAAAATAGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MISFKSFFMRTIIFQVLAILLLWGALIGWVKYSYYPDAEKYLDNQQRIVARGIANILDKTDVTNRSYLEVIKDIEVMYID
SIKNGMQDEIDYRPLFVVYDSNNQMLYASPSQEKPLFLPPSVLSGTISYANVKWHIAGSWSDKQQFRVIVGESFDNRTTI
FGNPAESTAIPLLVTLAAIIVTLLFTAYLSLRPLRQIARMISDRKPGTLSPINAAEQYQEIRPIVLEINKLMARIDAANQ
REKRFMADAAHELRTPIAAVLAQLHLLTQVADKTERQEIIEDMQQGLDRAASLSRQLIDLAKLESEDFPLKIETVNIHAE
IGKCIAQHVPYALEKNVELSLDGSENVMIDTDRHSLITIFTNLLENAIKYAPDGGRIEVNIRSLSPLGCYITVRDNGPGI
NPEYHKRLFERFYRVPGTLQVGSGLGLAIAKNLADKIGAQLRVAEGLDERGIGFVIDLPENYLVSSES

Sequences:

>Translated_468_residues
MISFKSFFMRTIIFQVLAILLLWGALIGWVKYSYYPDAEKYLDNQQRIVARGIANILDKTDVTNRSYLEVIKDIEVMYID
SIKNGMQDEIDYRPLFVVYDSNNQMLYASPSQEKPLFLPPSVLSGTISYANVKWHIAGSWSDKQQFRVIVGESFDNRTTI
FGNPAESTAIPLLVTLAAIIVTLLFTAYLSLRPLRQIARMISDRKPGTLSPINAAEQYQEIRPIVLEINKLMARIDAANQ
REKRFMADAAHELRTPIAAVLAQLHLLTQVADKTERQEIIEDMQQGLDRAASLSRQLIDLAKLESEDFPLKIETVNIHAE
IGKCIAQHVPYALEKNVELSLDGSENVMIDTDRHSLITIFTNLLENAIKYAPDGGRIEVNIRSLSPLGCYITVRDNGPGI
NPEYHKRLFERFYRVPGTLQVGSGLGLAIAKNLADKIGAQLRVAEGLDERGIGFVIDLPENYLVSSES
>Mature_468_residues
MISFKSFFMRTIIFQVLAILLLWGALIGWVKYSYYPDAEKYLDNQQRIVARGIANILDKTDVTNRSYLEVIKDIEVMYID
SIKNGMQDEIDYRPLFVVYDSNNQMLYASPSQEKPLFLPPSVLSGTISYANVKWHIAGSWSDKQQFRVIVGESFDNRTTI
FGNPAESTAIPLLVTLAAIIVTLLFTAYLSLRPLRQIARMISDRKPGTLSPINAAEQYQEIRPIVLEINKLMARIDAANQ
REKRFMADAAHELRTPIAAVLAQLHLLTQVADKTERQEIIEDMQQGLDRAASLSRQLIDLAKLESEDFPLKIETVNIHAE
IGKCIAQHVPYALEKNVELSLDGSENVMIDTDRHSLITIFTNLLENAIKYAPDGGRIEVNIRSLSPLGCYITVRDNGPGI
NPEYHKRLFERFYRVPGTLQVGSGLGLAIAKNLADKIGAQLRVAEGLDERGIGFVIDLPENYLVSSES

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=456, Percent_Identity=27.1929824561404, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786783, Length=297, Percent_Identity=30.3030303030303, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=28.4518828451883, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788279, Length=274, Percent_Identity=25.9124087591241, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=25.609756097561, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=28.0487804878049, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=278, Percent_Identity=27.3381294964029, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790551, Length=306, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=28.6919831223629, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=26.9896193771626, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082128, Length=301, Percent_Identity=26.2458471760797, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787374, Length=285, Percent_Identity=24.2105263157895, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=29.6610169491525, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=25.5707762557078, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081816, Length=256, Percent_Identity=26.953125, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=24.1379310344828, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790861, Length=248, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790346, Length=258, Percent_Identity=25.1937984496124, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52631; Mature: 52631

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFKSFFMRTIIFQVLAILLLWGALIGWVKYSYYPDAEKYLDNQQRIVARGIANILDKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHCC
DVTNRSYLEVIKDIEVMYIDSIKNGMQDEIDYRPLFVVYDSNNQMLYASPSQEKPLFLPP
CCCCHHHHHHHHHHHHEEEHHHHCCCHHCCCCCCEEEEEECCCEEEEECCCCCCCEECCH
SVLSGTISYANVKWHIAGSWSDKQQFRVIVGESFDNRTTIFGNPAESTAIPLLVTLAAII
HHHHCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHH
VTLLFTAYLSLRPLRQIARMISDRKPGTLSPINAAEQYQEIRPIVLEINKLMARIDAANQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
REKRFMADAAHELRTPIAAVLAQLHLLTQVADKTERQEIIEDMQQGLDRAASLSRQLIDL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLESEDFPLKIETVNIHAEIGKCIAQHVPYALEKNVELSLDGSENVMIDTDRHSLITIF
HHHCCCCCCEEEEEEEEHHHHHHHHHHHCCHHHCCCCEEEECCCCCEEEECCCHHHHHHH
TNLLENAIKYAPDGGRIEVNIRSLSPLGCYITVRDNGPGINPEYHKRLFERFYRVPGTLQ
HHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEE
VGSGLGLAIAKNLADKIGAQLRVAEGLDERGIGFVIDLPENYLVSSES
ECCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MISFKSFFMRTIIFQVLAILLLWGALIGWVKYSYYPDAEKYLDNQQRIVARGIANILDKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHCC
DVTNRSYLEVIKDIEVMYIDSIKNGMQDEIDYRPLFVVYDSNNQMLYASPSQEKPLFLPP
CCCCHHHHHHHHHHHHEEEHHHHCCCHHCCCCCCEEEEEECCCEEEEECCCCCCCEECCH
SVLSGTISYANVKWHIAGSWSDKQQFRVIVGESFDNRTTIFGNPAESTAIPLLVTLAAII
HHHHCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHH
VTLLFTAYLSLRPLRQIARMISDRKPGTLSPINAAEQYQEIRPIVLEINKLMARIDAANQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
REKRFMADAAHELRTPIAAVLAQLHLLTQVADKTERQEIIEDMQQGLDRAASLSRQLIDL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLESEDFPLKIETVNIHAEIGKCIAQHVPYALEKNVELSLDGSENVMIDTDRHSLITIF
HHHCCCCCCEEEEEEEEHHHHHHHHHHHCCHHHCCCCEEEECCCCCEEEECCCHHHHHHH
TNLLENAIKYAPDGGRIEVNIRSLSPLGCYITVRDNGPGINPEYHKRLFERFYRVPGTLQ
HHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEE
VGSGLGLAIAKNLADKIGAQLRVAEGLDERGIGFVIDLPENYLVSSES
ECCCCHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA