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The map label for this gene is tas [H]

Identifier: 157372063

GI number: 157372063

Start: 4235449

End: 4236489

Strand: Direct

Name: tas [H]

Synonym: Spro_3828

Alternate gene names: 157372063

Gene position: 4235449-4236489 (Clockwise)

Preceding gene: 157372062

Following gene: 157372067

Centisome position: 77.73

GC content: 56.68

Gene sequence:

>1041_bases
ATGCAATACCACCGTATTCCCCACAGTTCTTTAGAAGTGAGCGTGCTGGGACTGGGCACCATGACCTTTGGCGAACAGAA
CAGTGAAGCCGATGCCCATGCGCAACTCGACTATGCATTAGCCGCTGGCGTCAACCTGATTGACACCGCAGAGATGTACC
CGGTACCGCCCCGCCCTGAAACCCAGGGGCTGACCGAGCAATACATCGGCAGTTGGATCAAGGCACGCGGCAACCGTGAA
AAGATAGTGCTGGCCAGCAAGATTGCCGGGCCGGTGCGCGGTACCGACAGCAGCATCCGCCCGCAGCAGGCGCTGGATCG
CAAAAATATTCGTGTCGCGCTGGACGCCAGCCTGAAACGACTCAACACCGATTATCTCGATCTCTACCAATTGCACTGGC
CGCAGCGCCCGACCAACTACTTCGGCAAGCTCAATTATCAATACACCGACGATAAGGCCACCGTCACCCTGCTGGAAACG
CTGGAAGCGCTGACCGAACAGGTACGCGCCGGTAAAATCCGCTATATCGGGGTGTCTAACGAAACGCCATGGGGCGTAAT
GCGTTACCTGCAACTGGCTGAAAAACATGAGTTGCCGCGCATCGTCTCGATTCAAAACCCCTATAGCCTGCTGAACCGCA
GTTTTGAGATTGCCCTGGCGGAGATCAGCCAGCACGAAGGGGTTGAACTGTTGGCCTATTCCAGCCTGGCGTTCGGCACC
CTGAGCGGCAAGTATCTCAACGGTGCCAAGCCTGCCGGTGCACGCAACACGCTATTCACTCGCTTTAACCGCTACTCTGC
GCCACAAACGCAGTTGGCGATTGCCGAGTATGTCGCGTTAGCCAAAAAGCACGGGTTGGATCCGTCGCAGATGGCACTGG
CGTTTGTGCGCCAGCAGCCGTTCGTTGCCAGCACCCTGCTGGGTGCAACCACGCTGGAACAGCTGAAAACCAACATCGAC
AGTTTCGACGTGGTATTGAATGAAGACGTACTGCAGGGGCTGGAAGAGATCCACACCCGCTTTACTATTCCGGCACCATA
A

Upstream 100 bases:

>100_bases
AGTACACCGCCTTGCAGGTTGTTTGCCACAGCCTGCCCTTTGGCTCCTGTTTCACCGGGCGGTTTAGCCCGTAAGCGCTA
ACATGAAAGGAAGGCCGTTA

Downstream 100 bases:

>100_bases
AATACGTCCTGCGCCATAAATAAGATGGGGCGCCTAATCCGCGCCCCTTCTGCTATTTTGCCCGCCGCTGCGACAGCCAC
AGCGCGCTAATTGCCAGCGC

Product: putative aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQYHRIPHSSLEVSVLGLGTMTFGEQNSEADAHAQLDYALAAGVNLIDTAEMYPVPPRPETQGLTEQYIGSWIKARGNRE
KIVLASKIAGPVRGTDSSIRPQQALDRKNIRVALDASLKRLNTDYLDLYQLHWPQRPTNYFGKLNYQYTDDKATVTLLET
LEALTEQVRAGKIRYIGVSNETPWGVMRYLQLAEKHELPRIVSIQNPYSLLNRSFEIALAEISQHEGVELLAYSSLAFGT
LSGKYLNGAKPAGARNTLFTRFNRYSAPQTQLAIAEYVALAKKHGLDPSQMALAFVRQQPFVASTLLGATTLEQLKTNID
SFDVVLNEDVLQGLEEIHTRFTIPAP

Sequences:

>Translated_346_residues
MQYHRIPHSSLEVSVLGLGTMTFGEQNSEADAHAQLDYALAAGVNLIDTAEMYPVPPRPETQGLTEQYIGSWIKARGNRE
KIVLASKIAGPVRGTDSSIRPQQALDRKNIRVALDASLKRLNTDYLDLYQLHWPQRPTNYFGKLNYQYTDDKATVTLLET
LEALTEQVRAGKIRYIGVSNETPWGVMRYLQLAEKHELPRIVSIQNPYSLLNRSFEIALAEISQHEGVELLAYSSLAFGT
LSGKYLNGAKPAGARNTLFTRFNRYSAPQTQLAIAEYVALAKKHGLDPSQMALAFVRQQPFVASTLLGATTLEQLKTNID
SFDVVLNEDVLQGLEEIHTRFTIPAP
>Mature_346_residues
MQYHRIPHSSLEVSVLGLGTMTFGEQNSEADAHAQLDYALAAGVNLIDTAEMYPVPPRPETQGLTEQYIGSWIKARGNRE
KIVLASKIAGPVRGTDSSIRPQQALDRKNIRVALDASLKRLNTDYLDLYQLHWPQRPTNYFGKLNYQYTDDKATVTLLET
LEALTEQVRAGKIRYIGVSNETPWGVMRYLQLAEKHELPRIVSIQNPYSLLNRSFEIALAEISQHEGVELLAYSSLAFGT
LSGKYLNGAKPAGARNTLFTRFNRYSAPQTQLAIAEYVALAKKHGLDPSQMALAFVRQQPFVASTLLGATTLEQLKTNID
SFDVVLNEDVLQGLEEIHTRFTIPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=334, Percent_Identity=29.940119760479, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436962, Length=334, Percent_Identity=29.940119760479, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI27436969, Length=347, Percent_Identity=28.8184438040346, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27436966, Length=334, Percent_Identity=29.6407185628743, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4504825, Length=345, Percent_Identity=28.695652173913, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI27436971, Length=337, Percent_Identity=27.893175074184, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI223718702, Length=324, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI41152114, Length=319, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=75.1445086705202, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI87081735, Length=344, Percent_Identity=28.7790697674419, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788070, Length=341, Percent_Identity=28.4457478005865, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789375, Length=338, Percent_Identity=28.9940828402367, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1788081, Length=278, Percent_Identity=32.3741007194245, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=324, Percent_Identity=27.4691358024691, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=345, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=354, Percent_Identity=25.7062146892655, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=25.2788104089219, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=356, Percent_Identity=24.1573033707865, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320576, Length=343, Percent_Identity=26.2390670553936, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38589; Mature: 38589

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYHRIPHSSLEVSVLGLGTMTFGEQNSEADAHAQLDYALAAGVNLIDTAEMYPVPPRPE
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCC
TQGLTEQYIGSWIKARGNREKIVLASKIAGPVRGTDSSIRPQQALDRKNIRVALDASLKR
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCEEEEEEHHHHH
LNTDYLDLYQLHWPQRPTNYFGKLNYQYTDDKATVTLLETLEALTEQVRAGKIRYIGVSN
HCCCHHHHHHHCCCCCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCC
ETPWGVMRYLQLAEKHELPRIVSIQNPYSLLNRSFEIALAEISQHEGVELLAYSSLAFGT
CCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHEEHHHCCCCEEEEEECCHHHCC
LSGKYLNGAKPAGARNTLFTRFNRYSAPQTQLAIAEYVALAKKHGLDPSQMALAFVRQQP
CCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
FVASTLLGATTLEQLKTNIDSFDVVLNEDVLQGLEEIHTRFTIPAP
HHHHHHHHHHHHHHHHCCCCHHHEEECHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQYHRIPHSSLEVSVLGLGTMTFGEQNSEADAHAQLDYALAAGVNLIDTAEMYPVPPRPE
CCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCC
TQGLTEQYIGSWIKARGNREKIVLASKIAGPVRGTDSSIRPQQALDRKNIRVALDASLKR
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCEEEEEEHHHHH
LNTDYLDLYQLHWPQRPTNYFGKLNYQYTDDKATVTLLETLEALTEQVRAGKIRYIGVSN
HCCCHHHHHHHCCCCCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCC
ETPWGVMRYLQLAEKHELPRIVSIQNPYSLLNRSFEIALAEISQHEGVELLAYSSLAFGT
CCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHEEHHHCCCCEEEEEECCHHHCC
LSGKYLNGAKPAGARNTLFTRFNRYSAPQTQLAIAEYVALAKKHGLDPSQMALAFVRQQP
CCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
FVASTLLGATTLEQLKTNIDSFDVVLNEDVLQGLEEIHTRFTIPAP
HHHHHHHHHHHHHHHHCCCCHHHEEECHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]