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The map label for this gene is proX [H]

Identifier: 157371970

GI number: 157371970

Start: 4124443

End: 4125438

Strand: Direct

Name: proX [H]

Synonym: Spro_3735

Alternate gene names: 157371970

Gene position: 4124443-4125438 (Clockwise)

Preceding gene: 157371969

Following gene: 157371971

Centisome position: 75.69

GC content: 57.53

Gene sequence:

>996_bases
ATGCGCTCGACAGGAATTTGGGCTTTGGCCCTGACTTCATTGCTTGGCACACAGGCGTTCGCCGTCGAACTTCCCGGCAA
AGGCGTCACGGTTAAACCCTTGCAAAGCACCCTCGCCGAAGAAAGCTTTCAGACTGAGCTGGTCAACCGTGCGCTGACCC
AGCTGGGTTATAACGTCCAGCCGACCGCCGAGGTGGAATACAACATTGCCTACACCTCAATCGCTTCCGGTGACGCCACC
TATATGGCGGTGAACTGGGATCCGCTGCAAACCGACATGTACCAAAGCGCCGGCGGCGACAAAAAGTTTTATCGCCAGGG
CGCCTATATCACTAATGCAGCGCAGGGTTATCTGATTGACAAGAAAACCGCCGATAAATATCACATCAGCGATATTTCGC
AGTTGAAAGATCCCGAGCTGGCCAGGCTGTTTGACGCCGACGGTGACGGCAAGGCCGATCTGGCCGGTTGTGAGCCTGGC
TGGGTGTGCGGCAGCGCGATCAACACGCATATCAAAACCTATGGCCTGAGCAACACGGTTACTCAGAACCAGGGTAACTA
CTCCGCCATCATCGCCGACACCCTGACCCGCTACAAACAGGGTAAACCGGTGCTGTACTTCACCTGGACGCCGTACTGGG
TCAGCGACGAGCTGGTGCCCGGCCGCGATGTGGTCTGGTTGACCGTGCCGTTCTCCGCCAGCCCGGGTTCGTTGAAAGAC
AAGGATACCGCCTTGTCGAACGGCAAAAATTACGGCTTCTTCGTCAATAACGAGCATATCGTCGCCAACAAGCAATGGGC
GCAGGCCAACCCGGCGGCGGCCAAGCTGTTCGCCATCATGAAGCTGCCGTTGGCGGACGTAAATGCGCAGAACCTGCGGA
TGCACAAGGGCGAGAACAGCGCCGACGATATACAACGCCACGTAGACGGCTGGATTAAAGCCCACCAGGCCACCTTTGAC
GGCTGGGTCAGCACCGCTGCGGCGGCAGCGAAATAA

Upstream 100 bases:

>100_bases
ACGGCCCCATCGGCCTGGTCACCCGGCCCTTCATCAAAAAGCCTTAATTGCCCTGCCCCCGGCCAGCGTCGGGGGCACCG
ATAAAATCGAAGGAACCACT

Downstream 100 bases:

>100_bases
TCCCGACGTGCCGGAAATCCCGGCTTCATAACATAAAAAAGGTATTTCACTATGCGCACTACAGGAATCTGGGCGGTTGC
CCTCACCACATTGATTAGCT

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRSTGIWALALTSLLGTQAFAVELPGKGVTVKPLQSTLAEESFQTELVNRALTQLGYNVQPTAEVEYNIAYTSIASGDAT
YMAVNWDPLQTDMYQSAGGDKKFYRQGAYITNAAQGYLIDKKTADKYHISDISQLKDPELARLFDADGDGKADLAGCEPG
WVCGSAINTHIKTYGLSNTVTQNQGNYSAIIADTLTRYKQGKPVLYFTWTPYWVSDELVPGRDVVWLTVPFSASPGSLKD
KDTALSNGKNYGFFVNNEHIVANKQWAQANPAAAKLFAIMKLPLADVNAQNLRMHKGENSADDIQRHVDGWIKAHQATFD
GWVSTAAAAAK

Sequences:

>Translated_331_residues
MRSTGIWALALTSLLGTQAFAVELPGKGVTVKPLQSTLAEESFQTELVNRALTQLGYNVQPTAEVEYNIAYTSIASGDAT
YMAVNWDPLQTDMYQSAGGDKKFYRQGAYITNAAQGYLIDKKTADKYHISDISQLKDPELARLFDADGDGKADLAGCEPG
WVCGSAINTHIKTYGLSNTVTQNQGNYSAIIADTLTRYKQGKPVLYFTWTPYWVSDELVPGRDVVWLTVPFSASPGSLKD
KDTALSNGKNYGFFVNNEHIVANKQWAQANPAAAKLFAIMKLPLADVNAQNLRMHKGENSADDIQRHVDGWIKAHQATFD
GWVSTAAAAAK
>Mature_331_residues
MRSTGIWALALTSLLGTQAFAVELPGKGVTVKPLQSTLAEESFQTELVNRALTQLGYNVQPTAEVEYNIAYTSIASGDAT
YMAVNWDPLQTDMYQSAGGDKKFYRQGAYITNAAQGYLIDKKTADKYHISDISQLKDPELARLFDADGDGKADLAGCEPG
WVCGSAINTHIKTYGLSNTVTQNQGNYSAIIADTLTRYKQGKPVLYFTWTPYWVSDELVPGRDVVWLTVPFSASPGSLKD
KDTALSNGKNYGFFVNNEHIVANKQWAQANPAAAKLFAIMKLPLADVNAQNLRMHKGENSADDIQRHVDGWIKAHQATFD
GWVSTAAAAAK

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=331, Percent_Identity=65.558912386707, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 36144; Mature: 36144

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTGIWALALTSLLGTQAFAVELPGKGVTVKPLQSTLAEESFQTELVNRALTQLGYNVQ
CCCCCHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PTAEVEYNIAYTSIASGDATYMAVNWDPLQTDMYQSAGGDKKFYRQGAYITNAAQGYLID
CCCEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCCCCHHHHHCCCEEECCCCCEEEE
KKTADKYHISDISQLKDPELARLFDADGDGKADLAGCEPGWVCGSAINTHIKTYGLSNTV
CCCCCCEECCHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCEECHHHHCEEEEECCCCCE
TQNQGNYSAIIADTLTRYKQGKPVLYFTWTPYWVSDELVPGRDVVWLTVPFSASPGSLKD
ECCCCCEEEEHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCEEEEEEECCCCCCCCCC
KDTALSNGKNYGFFVNNEHIVANKQWAQANPAAAKLFAIMKLPLADVNAQNLRMHKGENS
CHHHHCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCC
ADDIQRHVDGWIKAHQATFDGWVSTAAAAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRSTGIWALALTSLLGTQAFAVELPGKGVTVKPLQSTLAEESFQTELVNRALTQLGYNVQ
CCCCCHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PTAEVEYNIAYTSIASGDATYMAVNWDPLQTDMYQSAGGDKKFYRQGAYITNAAQGYLID
CCCEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCCCCHHHHHCCCEEECCCCCEEEE
KKTADKYHISDISQLKDPELARLFDADGDGKADLAGCEPGWVCGSAINTHIKTYGLSNTV
CCCCCCEECCHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCEECHHHHCEEEEECCCCCE
TQNQGNYSAIIADTLTRYKQGKPVLYFTWTPYWVSDELVPGRDVVWLTVPFSASPGSLKD
ECCCCCEEEEHHHHHHHHHCCCCEEEEEECCEEECCCCCCCCCEEEEEEECCCCCCCCCC
KDTALSNGKNYGFFVNNEHIVANKQWAQANPAAAKLFAIMKLPLADVNAQNLRMHKGENS
CHHHHCCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCC
ADDIQRHVDGWIKAHQATFDGWVSTAAAAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]