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The map label for this gene is acpS

Identifier: 157371900

GI number: 157371900

Start: 4058569

End: 4058949

Strand: Reverse

Name: acpS

Synonym: Spro_3665

Alternate gene names: 157371900

Gene position: 4058949-4058569 (Counterclockwise)

Preceding gene: 157371901

Following gene: 157371896

Centisome position: 74.49

GC content: 58.01

Gene sequence:

>381_bases
ATGGCAGTGCTGGGGCTGGGTACCGACATTGTCGAAATGGCGCGCATTGAAGCCGTCGTTGAGCGCAGTGGCGATCGTCT
GGCGCGCCGCGTGCTGAGCGAGGCTGAATGGGAATTGTACCAGCAACATCAGCAGCCGGTGCGCTTTCTGGCCAAACGTT
TTGCGGTGAAAGAAGCCGTCGCCAAGGCGTTTGGCACCGGTATTCGCAATGGGCTGGCGTTTAATCAGTTTGAAGTGTTC
AACGACGGTCTCGGCAAGCCGAATATTCGCCTGCATGCTCGCGCCGCCGAGCTGGCAAAGGAAATGGGGGTCACCTCGAT
CCATGTTTCGCTGGCGGATGAACGTCGCTATGCCTGTGCCACGGTGATTATCGAAGGGTAA

Upstream 100 bases:

>100_bases
AGCTAAATATCGGCCACGCTATTATCGGCCAGGCGGTGATGTGTGGGTTACCGGCAGCGGTGACTGACATGAAATTGCTG
ATGCGCGAAGCGCGTCGCTA

Downstream 100 bases:

>100_bases
TGGTTTTATCCGGCGACAAAATCAAAGGGCGCCTGTAGGCGCCGTTGTTGATCTGACTGCGTGGTCAGAGTCGGTCGGCG
TGGTGCAGCACCACAAATTT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MAVLGLGTDIVEMARIEAVVERSGDRLARRVLSEAEWELYQQHQQPVRFLAKRFAVKEAVAKAFGTGIRNGLAFNQFEVF
NDGLGKPNIRLHARAAELAKEMGVTSIHVSLADERRYACATVIIEG

Sequences:

>Translated_126_residues
MAVLGLGTDIVEMARIEAVVERSGDRLARRVLSEAEWELYQQHQQPVRFLAKRFAVKEAVAKAFGTGIRNGLAFNQFEVF
NDGLGKPNIRLHARAAELAKEMGVTSIHVSLADERRYACATVIIEG
>Mature_125_residues
AVLGLGTDIVEMARIEAVVERSGDRLARRVLSEAEWELYQQHQQPVRFLAKRFAVKEAVAKAFGTGIRNGLAFNQFEVFN
DGLGKPNIRLHARAAELAKEMGVTSIHVSLADERRYACATVIIEG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=76.8, Blast_Score=201, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_SERP5 (A8GI21)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479889.1
- ProteinModelPortal:   A8GI21
- SMR:   A8GI21
- STRING:   A8GI21
- GeneID:   5606404
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3665
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK00070
- BioCyc:   SPRO399741:SPRO_3665-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13967; Mature: 13836

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLGLGTDIVEMARIEAVVERSGDRLARRVLSEAEWELYQQHQQPVRFLAKRFAVKEAV
CEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKAFGTGIRNGLAFNQFEVFNDGLGKPNIRLHARAAELAKEMGVTSIHVSLADERRYACA
HHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCEEEEEECCCCCEEEE
TVIIEG
EEEECC
>Mature Secondary Structure 
AVLGLGTDIVEMARIEAVVERSGDRLARRVLSEAEWELYQQHQQPVRFLAKRFAVKEAV
EEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKAFGTGIRNGLAFNQFEVFNDGLGKPNIRLHARAAELAKEMGVTSIHVSLADERRYACA
HHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCEEEEEECCCCCEEEE
TVIIEG
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA