Click here to switch to the map view.

The map label for this gene is ppk [H]

Identifier: 157371776

GI number: 157371776

Start: 3910243

End: 3912306

Strand: Direct

Name: ppk [H]

Synonym: Spro_3541

Alternate gene names: 157371776

Gene position: 3910243-3912306 (Clockwise)

Preceding gene: 157371765

Following gene: 157371777

Centisome position: 71.76

GC content: 52.18

Gene sequence:

>2064_bases
ATGGGTCAGGAAAAGCTCTACATCGAAAAAGAACTAAGCTGGTTATCCTTTAATGAACGCGTATTGCAGGAAGCCGCAGA
TAAGAGCAATCCCCTGATTGAGCGCATGCGTTTTCTGGGCATTTACTCCAATAACCTTGACGAGTTCTATAAGGTCCGCT
TTGCCGATCTCAAACGACGCATTCTGATCAGCGAAGAACAAGGCTCTGGCGGCGCTTCACGCCATCTGCTGAAAAAGATC
CAGGCCAAGGTATTAAAAACCGATCAAGAATTCGACAGCCTGTATAACGATTTGCTGCTGGAAATGGCGCGTAATCAGAT
CTTCCTGATCAACGAACGTCAGGTGTCGGAGAACCAGCAAATCTGGCTGCGACAATACTTCAAGCAGCATCTGCGTCAAC
ACATCACGCCCATCCTGATCAATCACGAAACCAACCTGGTGCAGTTCCTGAAAGACGATTACACCTATCTGGCGGTGGAG
ATTATTCGCGGCATACGCATCGATTATGCGCTGCTGGAGATCCCGTCCGACAAGGTGCCGCGCTTCGTCAACCTGCCGCC
GGAAGCCCCGCGCCGTCGCAAACCGATGATCCTGCTGGACAACATTCTGCGCTACTGCCTGGACGATATTTTCAAGGGCT
TCTTCGACTACGACGCGCTCAATGCCTATTCGATGAAAATGACCCGCGACGCGGAATATGATCTGGTCACTGAGATGGAA
TCGAGCCTGTTGGAACTGATGTCCTCCAGCCTGAAACAGCGCCTGACCGCCGAGCCGGTACGTTTTGTTTATCAGCGCGA
CATGCCGAATGAAATGGTGGAGTTGCTGCGCGGCAAGCTGGGTATCTCCAACTATGACTCGGTGATCGCCGGCGGCCGCT
ATCATAACTTTAAAGACTTTATCGGCTTCCCGAACGTCGGCAAGGCCAATCTGGTCAACAAACCGCTGCCACGCCTGCGC
CATACCTGGTTCGAAAAGTTCCGCAACGGTTTTGACGCCATCCGCGAACAGGACGTGCTGCTTTACTACCCGTACCACAC
CTTTGAACACGTGCTGGAACTGGTGCGTCAGGCGTCATTTGACCCTAGCGTGCTGGCGATAAAAATCAATATTTACCGCG
TGGCGAAAGACTCACGTATCATCGAATCGATGATCCACGCCGCCCACAACGGCAAGAAAGTCACGGTGGTGGTAGAGCTG
CAGGCACGTTTTGATGAAGAGGCCAACATCCACTGGGCCAAGCGCCTGACGGAAGCCGGCGTGCACGTAATCTTCTCTGC
TCCGGGCCTGAAAATCCACGCCAAACTGTTCCTGATCTCACGCCGTGAAGGCGACGAGATTGTGCGCTATGCTCATATCG
GTACCGGCAACTTTAACGAGAAAACCGCGCGTATTTATACCGACTATTCATTGCTGACCGCCGACTCACGCATCACCAAC
GAAGTGCGTCGGGTGTTTAACTTTATCGAAAACCCGTACCGACCGGTCACCTTCGACAACCTGATGGTGTCGCCGCAGAA
CTCGCGCCTGAAGCTGTATGAGTTAATCGACCGGGAAATTGCCAATGCCGAGGCCGGGCTTCCCGCCGGCATTATGCTGA
AAATCAACAATCTGGTGGATAAAGGGCTGGTAGATCGGTTATATACCGCATCCGGCGCCGGTGTAAAAATCCGCCTGTTG
GTGCGAGGTATGTGTTCTTTGATTCCCAACCTGCCGGGGATCAGTGACAATATTCAAGTAATCAGCATCGTCGACCGTTA
TCTGGAACACGACCGGGTTTACGTTTTCGAAAACAAAGGTGACAAACTGGTTTATCTGTCCTCTGCCGACTGGATGACCC
GTAACATAGATTACCGCATCGAAGTCGCGGTCTCGCTGCTGGATCCAACGCTGAAACAACGAGTTCTGGATATTCTGGAA
ATCCTGTTCAGCGACACGGTCAAGGCACGTTACCTCGATAAAGAACTGAGCAACCAGTACGTACCGCGCGGCAACCGCCG
TAAAGTCCGTTCTCAGGTTGCCATTTACGAGTATTTAAAAGCTCTGGAACAACCAGGACAGTAG

Upstream 100 bases:

>100_bases
TTGGACTTTCCTGTCAATCTCTCGCAATAATGATGAAGGACACTGAAGCGGCATCCGGGCTGCGTCCCGGATCCTTTTCT
AAAATTGAACTGGAGTGGCA

Downstream 100 bases:

>100_bases
GCCAGCAACTATGCCGCTAAAAAGCACTGCAACAAATAAACCGCAGGAAATTGCTGCCATCGACCTCGGGTCGAACAGCT
TCCATATGGTGATTGCCCGC

Product: polyphosphate kinase

Products: NA

Alternate protein names: ATP-polyphosphate phosphotransferase; Polyphosphoric acid kinase [H]

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFADLKRRILISEEQGSGGASRHLLKKI
QAKVLKTDQEFDSLYNDLLLEMARNQIFLINERQVSENQQIWLRQYFKQHLRQHITPILINHETNLVQFLKDDYTYLAVE
IIRGIRIDYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVTEME
SSLLELMSSSLKQRLTAEPVRFVYQRDMPNEMVELLRGKLGISNYDSVIAGGRYHNFKDFIGFPNVGKANLVNKPLPRLR
HTWFEKFRNGFDAIREQDVLLYYPYHTFEHVLELVRQASFDPSVLAIKINIYRVAKDSRIIESMIHAAHNGKKVTVVVEL
QARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRREGDEIVRYAHIGTGNFNEKTARIYTDYSLLTADSRITN
EVRRVFNFIENPYRPVTFDNLMVSPQNSRLKLYELIDREIANAEAGLPAGIMLKINNLVDKGLVDRLYTASGAGVKIRLL
VRGMCSLIPNLPGISDNIQVISIVDRYLEHDRVYVFENKGDKLVYLSSADWMTRNIDYRIEVAVSLLDPTLKQRVLDILE
ILFSDTVKARYLDKELSNQYVPRGNRRKVRSQVAIYEYLKALEQPGQ

Sequences:

>Translated_687_residues
MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFADLKRRILISEEQGSGGASRHLLKKI
QAKVLKTDQEFDSLYNDLLLEMARNQIFLINERQVSENQQIWLRQYFKQHLRQHITPILINHETNLVQFLKDDYTYLAVE
IIRGIRIDYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVTEME
SSLLELMSSSLKQRLTAEPVRFVYQRDMPNEMVELLRGKLGISNYDSVIAGGRYHNFKDFIGFPNVGKANLVNKPLPRLR
HTWFEKFRNGFDAIREQDVLLYYPYHTFEHVLELVRQASFDPSVLAIKINIYRVAKDSRIIESMIHAAHNGKKVTVVVEL
QARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRREGDEIVRYAHIGTGNFNEKTARIYTDYSLLTADSRITN
EVRRVFNFIENPYRPVTFDNLMVSPQNSRLKLYELIDREIANAEAGLPAGIMLKINNLVDKGLVDRLYTASGAGVKIRLL
VRGMCSLIPNLPGISDNIQVISIVDRYLEHDRVYVFENKGDKLVYLSSADWMTRNIDYRIEVAVSLLDPTLKQRVLDILE
ILFSDTVKARYLDKELSNQYVPRGNRRKVRSQVAIYEYLKALEQPGQ
>Mature_686_residues
GQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFADLKRRILISEEQGSGGASRHLLKKIQ
AKVLKTDQEFDSLYNDLLLEMARNQIFLINERQVSENQQIWLRQYFKQHLRQHITPILINHETNLVQFLKDDYTYLAVEI
IRGIRIDYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVTEMES
SLLELMSSSLKQRLTAEPVRFVYQRDMPNEMVELLRGKLGISNYDSVIAGGRYHNFKDFIGFPNVGKANLVNKPLPRLRH
TWFEKFRNGFDAIREQDVLLYYPYHTFEHVLELVRQASFDPSVLAIKINIYRVAKDSRIIESMIHAAHNGKKVTVVVELQ
ARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRREGDEIVRYAHIGTGNFNEKTARIYTDYSLLTADSRITNE
VRRVFNFIENPYRPVTFDNLMVSPQNSRLKLYELIDREIANAEAGLPAGIMLKINNLVDKGLVDRLYTASGAGVKIRLLV
RGMCSLIPNLPGISDNIQVISIVDRYLEHDRVYVFENKGDKLVYLSSADWMTRNIDYRIEVAVSLLDPTLKQRVLDILEI
LFSDTVKARYLDKELSNQYVPRGNRRKVRSQVAIYEYLKALEQPGQ

Specific function: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) [H]

COG id: COG0855

COG function: function code P; Polyphosphate kinase

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PLD phosphodiesterase domain [H]

Homologues:

Organism=Escherichia coli, GI1788847, Length=687, Percent_Identity=88.0640465793304, Blast_Score=1246, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736
- InterPro:   IPR003414 [H]

Pfam domain/function: PF02503 PP_kinase [H]

EC number: =2.7.4.1 [H]

Molecular weight: Translated: 79961; Mature: 79830

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFADLKRR
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ILISEEQGSGGASRHLLKKIQAKVLKTDQEFDSLYNDLLLEMARNQIFLINERQVSENQQ
EEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
IWLRQYFKQHLRQHITPILINHETNLVQFLKDDYTYLAVEIIRGIRIDYALLEIPSDKVP
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCC
RFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVTEME
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHH
SSLLELMSSSLKQRLTAEPVRFVYQRDMPNEMVELLRGKLGISNYDSVIAGGRYHNFKDF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHH
IGFPNVGKANLVNKPLPRLRHTWFEKFRNGFDAIREQDVLLYYPYHTFEHVLELVRQASF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCC
DPSVLAIKINIYRVAKDSRIIESMIHAAHNGKKVTVVVELQARFDEEANIHWAKRLTEAG
CCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCC
VHVIFSAPGLKIHAKLFLISRREGDEIVRYAHIGTGNFNEKTARIYTDYSLLTADSRITN
EEEEEECCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECEEEEECCHHHHH
EVRRVFNFIENPYRPVTFDNLMVSPQNSRLKLYELIDREIANAEAGLPAGIMLKINNLVD
HHHHHHHHHCCCCCCEEECCEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEHHHHH
KGLVDRLYTASGAGVKIRLLVRGMCSLIPNLPGISDNIQVISIVDRYLEHDRVYVFENKG
HHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCC
DKLVYLSSADWMTRNIDYRIEVAVSLLDPTLKQRVLDILEILFSDTVKARYLDKELSNQY
CEEEEEECCCCEECCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
VPRGNRRKVRSQVAIYEYLKALEQPGQ
CCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFADLKRR
CCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ILISEEQGSGGASRHLLKKIQAKVLKTDQEFDSLYNDLLLEMARNQIFLINERQVSENQQ
EEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
IWLRQYFKQHLRQHITPILINHETNLVQFLKDDYTYLAVEIIRGIRIDYALLEIPSDKVP
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCC
RFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVTEME
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHH
SSLLELMSSSLKQRLTAEPVRFVYQRDMPNEMVELLRGKLGISNYDSVIAGGRYHNFKDF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHH
IGFPNVGKANLVNKPLPRLRHTWFEKFRNGFDAIREQDVLLYYPYHTFEHVLELVRQASF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHCCC
DPSVLAIKINIYRVAKDSRIIESMIHAAHNGKKVTVVVELQARFDEEANIHWAKRLTEAG
CCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCC
VHVIFSAPGLKIHAKLFLISRREGDEIVRYAHIGTGNFNEKTARIYTDYSLLTADSRITN
EEEEEECCCCEEEEEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECEEEEECCHHHHH
EVRRVFNFIENPYRPVTFDNLMVSPQNSRLKLYELIDREIANAEAGLPAGIMLKINNLVD
HHHHHHHHHCCCCCCEEECCEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEHHHHH
KGLVDRLYTASGAGVKIRLLVRGMCSLIPNLPGISDNIQVISIVDRYLEHDRVYVFENKG
HHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCC
DKLVYLSSADWMTRNIDYRIEVAVSLLDPTLKQRVLDILEILFSDTVKARYLDKELSNQY
CEEEEEECCCCEECCCCEEEEEEHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
VPRGNRRKVRSQVAIYEYLKALEQPGQ
CCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]