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The map label for this gene is mmuP [H]

Identifier: 157371707

GI number: 157371707

Start: 3841830

End: 3843239

Strand: Direct

Name: mmuP [H]

Synonym: Spro_3470

Alternate gene names: 157371707

Gene position: 3841830-3843239 (Clockwise)

Preceding gene: 157371702

Following gene: 157371708

Centisome position: 70.51

GC content: 60.0

Gene sequence:

>1410_bases
ATGCACTCAGCCGTTCCCGCCGAAGGGCAGTTCAAACGCACCATGAAGGCCCGACATTTGGTGATGCTGTCGCTGGGCGG
CGTGATTGGTACCGGGCTGTTCTTCAACACCGGCTATATCATTTCCACTACCGGTGCTCTCGGCACCCTGCTGGCCTATC
TGATCGGCGCATTGGTGGTCTATCTGGTGATGCTGTGCCTGGGTGAACTGTCGGTGGCGATGCCGGAAACCGGCGCCTTC
CACGTCTACGCATCACGCTATCTTGGCCCGGCCACCGGTTACACCGTCGCCTGGCTGTACTGGCTGACCTGGACGGTCGC
GCTGGGTTCGAGCCTGACCGCCGCCGGTTTCTGCATGCAGTATTGGTTCCCGCAATCACCGGTGTGGCTGTGGTGTTTGA
TCTTCTGCGCGGCGATTTTCCTGCTTAACGTGGTCACGACCCGCTTCTTTGCTGAGAGCGAATTCTGGTTCTCGCTGATC
AAGGTCGTTACCATTCTGGCGTTTATCATCCTCGGCGGTGCGGCCATGTTCGGCCTGCTGCCGATGAAAGACGGCACGCC
AGCGCCCTTCCTGCATAACCTGACCGCCTCCGGCTGGCTGCCAAACGGCACCTTGCCGATCCTGATGACCATGGTGGCCG
TGAATTTCGCATTCTCCGGCACTGAGCTTATCGGCATTGCCGCCGGTGAAACCGAGAACCCGGAAAAGGTGGTGCCCTGG
GCGATACGTACCACGGTGATCCGCCTGATGCTGTTCTTTATCGGGACGGTATTTATTCTGGCGGCGCTGATCCCGATGGA
TCAGGCCGGGATTGTCAAAAGCCCGTTTGTGCTGGTGTTTGAACGCATCGGGGTGCCCTATGCCGCCGATATCTTTAATT
TCGTGATCCTGACCGCCATCCTGTCGGCAGCCAATTCGGGCCTGTACGCGTCGGGCCGCATGCTGTGGTCGCTGGCCAAC
CAGCGCACCCTGCCGGCCTATTTCTCCCGCGTGAATAAACGCGGTATCCCGATCAACGCGCTGACCTTCAGCATGCTCGG
CGGCGTACTGGCATTGCTGACCAGCGTGATCGCCCCGGACACGGTGTTCGTGGCGCTGTCGGCAATTTCCGGTTTTGCAG
TGGTGGTGGTCTGGTTGAGCATCTGTGCCTCGCACTTCGCTTTCCGCCGTCATTATGTCCGCAGCGGCCAGCCCATTTCC
GGTCTTAAATACCGCGCGCCGGGTTACCCGCTAACGCCGATCGTTGGTTTCACCCTGTGCCTGCTGGCCTGCGTCGGGCT
GGCGTTCGATCCGGAGCAGCGCATCGCGCTTTACTGCGGGCTGCCCTTTGTCGCCCTGTGCTACATCGCCTATTACCTGA
CCCGCCGTGCCGGGCAAAAAACCTCTCTGGGAGAGAATCATGTCGGTTAA

Upstream 100 bases:

>100_bases
TTTTGCTTTATGGTTTCCGCTCACACATTGATTTCATGAAGTATTGCGGGTATAACTGATAGCCATTTAGCTGTTTAGAC
GTCTATACGGATAGAATATT

Downstream 100 bases:

>100_bases
CAACCCTGTCGCCACACTCTTGAGCGCCCACCCTACGCTGATTTTAGACGGCGCACTGGCCACCGAACTGGAAGCCCGCG
GCTGCGATCTGAGCGATCCG

Product: S-methylmethionine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MHSAVPAEGQFKRTMKARHLVMLSLGGVIGTGLFFNTGYIISTTGALGTLLAYLIGALVVYLVMLCLGELSVAMPETGAF
HVYASRYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQSPVWLWCLIFCAAIFLLNVVTTRFFAESEFWFSLI
KVVTILAFIILGGAAMFGLLPMKDGTPAPFLHNLTASGWLPNGTLPILMTMVAVNFAFSGTELIGIAAGETENPEKVVPW
AIRTTVIRLMLFFIGTVFILAALIPMDQAGIVKSPFVLVFERIGVPYAADIFNFVILTAILSAANSGLYASGRMLWSLAN
QRTLPAYFSRVNKRGIPINALTFSMLGGVLALLTSVIAPDTVFVALSAISGFAVVVVWLSICASHFAFRRHYVRSGQPIS
GLKYRAPGYPLTPIVGFTLCLLACVGLAFDPEQRIALYCGLPFVALCYIAYYLTRRAGQKTSLGENHVG

Sequences:

>Translated_469_residues
MHSAVPAEGQFKRTMKARHLVMLSLGGVIGTGLFFNTGYIISTTGALGTLLAYLIGALVVYLVMLCLGELSVAMPETGAF
HVYASRYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQSPVWLWCLIFCAAIFLLNVVTTRFFAESEFWFSLI
KVVTILAFIILGGAAMFGLLPMKDGTPAPFLHNLTASGWLPNGTLPILMTMVAVNFAFSGTELIGIAAGETENPEKVVPW
AIRTTVIRLMLFFIGTVFILAALIPMDQAGIVKSPFVLVFERIGVPYAADIFNFVILTAILSAANSGLYASGRMLWSLAN
QRTLPAYFSRVNKRGIPINALTFSMLGGVLALLTSVIAPDTVFVALSAISGFAVVVVWLSICASHFAFRRHYVRSGQPIS
GLKYRAPGYPLTPIVGFTLCLLACVGLAFDPEQRIALYCGLPFVALCYIAYYLTRRAGQKTSLGENHVG
>Mature_469_residues
MHSAVPAEGQFKRTMKARHLVMLSLGGVIGTGLFFNTGYIISTTGALGTLLAYLIGALVVYLVMLCLGELSVAMPETGAF
HVYASRYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQYWFPQSPVWLWCLIFCAAIFLLNVVTTRFFAESEFWFSLI
KVVTILAFIILGGAAMFGLLPMKDGTPAPFLHNLTASGWLPNGTLPILMTMVAVNFAFSGTELIGIAAGETENPEKVVPW
AIRTTVIRLMLFFIGTVFILAALIPMDQAGIVKSPFVLVFERIGVPYAADIFNFVILTAILSAANSGLYASGRMLWSLAN
QRTLPAYFSRVNKRGIPINALTFSMLGGVLALLTSVIAPDTVFVALSAISGFAVVVVWLSICASHFAFRRHYVRSGQPIS
GLKYRAPGYPLTPIVGFTLCLLACVGLAFDPEQRIALYCGLPFVALCYIAYYLTRRAGQKTSLGENHVG

Specific function: Transporter for the intake of S-methylmethionine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=352, Percent_Identity=24.1477272727273, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI115648022, Length=352, Percent_Identity=24.1477272727273, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI258645169, Length=389, Percent_Identity=21.5938303341902, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87081708, Length=451, Percent_Identity=80.9312638580931, Blast_Score=747, Evalue=0.0,
Organism=Escherichia coli, GI1788480, Length=460, Percent_Identity=39.7826086956522, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1786602, Length=465, Percent_Identity=36.1290322580645, Blast_Score=284, Evalue=7e-78,
Organism=Escherichia coli, GI1786302, Length=416, Percent_Identity=36.7788461538462, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI48994972, Length=465, Percent_Identity=35.2688172043011, Blast_Score=264, Evalue=9e-72,
Organism=Escherichia coli, GI1786789, Length=420, Percent_Identity=35.9523809523809, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1790653, Length=395, Percent_Identity=34.4303797468354, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI87081915, Length=452, Percent_Identity=31.4159292035398, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1789017, Length=444, Percent_Identity=33.1081081081081, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI2367353, Length=412, Percent_Identity=25.7281553398058, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081869, Length=328, Percent_Identity=23.4756097560976, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=411, Percent_Identity=23.1143552311436, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320772, Length=470, Percent_Identity=31.9148936170213, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6324061, Length=416, Percent_Identity=32.2115384615385, Blast_Score=219, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6324553, Length=410, Percent_Identity=33.9024390243902, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6324990, Length=474, Percent_Identity=31.4345991561181, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6321629, Length=472, Percent_Identity=29.2372881355932, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6324059, Length=426, Percent_Identity=33.5680751173709, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6321053, Length=454, Percent_Identity=30.1762114537445, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320717, Length=421, Percent_Identity=31.353919239905, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322892, Length=474, Percent_Identity=29.535864978903, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6319824, Length=416, Percent_Identity=30.7692307692308, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6319542, Length=425, Percent_Identity=28.7058823529412, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324924, Length=485, Percent_Identity=28.659793814433, Blast_Score=180, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6319543, Length=414, Percent_Identity=28.9855072463768, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320251, Length=420, Percent_Identity=27.6190476190476, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322967, Length=477, Percent_Identity=27.8825995807128, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324981, Length=481, Percent_Identity=29.7297297297297, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319608, Length=431, Percent_Identity=22.737819025522, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320364, Length=527, Percent_Identity=23.719165085389, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45550968, Length=496, Percent_Identity=22.9838709677419, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19921172, Length=496, Percent_Identity=22.9838709677419, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50854; Mature: 50854

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSAVPAEGQFKRTMKARHLVMLSLGGVIGTGLFFNTGYIISTTGALGTLLAYLIGALVV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
YLVMLCLGELSVAMPETGAFHVYASRYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQ
HHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
YWFPQSPVWLWCLIFCAAIFLLNVVTTRFFAESEFWFSLIKVVTILAFIILGGAAMFGLL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
PMKDGTPAPFLHNLTASGWLPNGTLPILMTMVAVNFAFSGTELIGIAAGETENPEKVVPW
ECCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
AIRTTVIRLMLFFIGTVFILAALIPMDQAGIVKSPFVLVFERIGVPYAADIFNFVILTAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LSAANSGLYASGRMLWSLANQRTLPAYFSRVNKRGIPINALTFSMLGGVLALLTSVIAPD
HHHHCCCCEECCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
TVFVALSAISGFAVVVVWLSICASHFAFRRHYVRSGQPISGLKYRAPGYPLTPIVGFTLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHH
LLACVGLAFDPEQRIALYCGLPFVALCYIAYYLTRRAGQKTSLGENHVG
HHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHSAVPAEGQFKRTMKARHLVMLSLGGVIGTGLFFNTGYIISTTGALGTLLAYLIGALVV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHH
YLVMLCLGELSVAMPETGAFHVYASRYLGPATGYTVAWLYWLTWTVALGSSLTAAGFCMQ
HHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
YWFPQSPVWLWCLIFCAAIFLLNVVTTRFFAESEFWFSLIKVVTILAFIILGGAAMFGLL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
PMKDGTPAPFLHNLTASGWLPNGTLPILMTMVAVNFAFSGTELIGIAAGETENPEKVVPW
ECCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
AIRTTVIRLMLFFIGTVFILAALIPMDQAGIVKSPFVLVFERIGVPYAADIFNFVILTAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
LSAANSGLYASGRMLWSLANQRTLPAYFSRVNKRGIPINALTFSMLGGVLALLTSVIAPD
HHHHCCCCEECCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
TVFVALSAISGFAVVVVWLSICASHFAFRRHYVRSGQPISGLKYRAPGYPLTPIVGFTLC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHH
LLACVGLAFDPEQRIALYCGLPFVALCYIAYYLTRRAGQKTSLGENHVG
HHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9882684 [H]