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The map label for this gene is fadL [H]

Identifier: 157371618

GI number: 157371618

Start: 3742120

End: 3743442

Strand: Direct

Name: fadL [H]

Synonym: Spro_3381

Alternate gene names: 157371618

Gene position: 3742120-3743442 (Clockwise)

Preceding gene: 157371613

Following gene: 157371629

Centisome position: 68.68

GC content: 54.95

Gene sequence:

>1323_bases
ATGAGCCAGAAAAACCTATTTACTAAATCAGCTCTCGCAGCTGCAGTGGCAATTATTTCTTCAAACGTGTCTGCCGCAGG
ATTCCAGCTGAATGAGTTTTCATCAGCTGGTTTAGGACGTTCGTATTCTGGCGAAGGCGCCATGGCAGATACTGCGGCTT
CCGCCAGCCGTAACCCGGCCCTGTTGATGATGTACACCCGCCCGGAACTCTCCCTTGGCGCGGTATTTATCGATCCGGAC
GTGGACATTACCGGCAAGTCACCTTCCGGTGCCAGCCTTGACTCCAAGAACATCGCCCCTACCGCCTGGGTGCCAAACCT
GCATTATGTTCAACCGATTAACGATCAGTTTGCCGTAGGTGGCTCTGTCACCAGCAACTACGGCCTGGCGACCGAATTCA
ACGACGGTTACACCGCCGGGGCTTACGGTGGTAAAACCGACCTGACCACCGTGAACCTGAACCTGAGCGGGGCTTATCGC
CTCAATCAACAATTCAGCTTCGGTCTGGGCTTCGATGCGGTTTACGCCAAAGCCAAGCTCGAGCGTTATGCCGGCGAATT
GCCGAAATTGATCGCAGGCTCTGGCCAGTTGCCTCCGCAATTGGCGGGCCCGGTATCACAGATCCCAGCGGATACCCAAA
TTTCTCACCTGAAGGGTGACAAATGGGGCTTTGGCTGGAACGCCGGCATTCTGTATGAAGTGGATGAAAACAACCGTTAC
GGTTTCACCTACCGTTCCGAAGTCAAAATCAAGTTTGACGGCGACTACAAGAGCAGCCTGCCATCCGCCTATAACCCGCT
GCTGGGCGCTCTCGGTCTGCCTATGGGCACCGACGGCACCACCATCCCCGGTTCTCTGGACTTGAACCTGCCGGAAATGT
GGGAAATCTCGGGTTACAACAAGGTTGCACCGCAGTGGGCCATCCACTACAGCCTGGCTTACACCAGCTGGAGCCAGTTC
CAGGAGCTGAAAGCTACCGGCAACAACGGTCAAACGCTGTTTGAGAAGCATGAAGGCTTTAAAGACGCTTACCGTATCGC
ACTGGGTACCACCTACTTCTATGACGATAACTGGACCTTCCGTACCGGTATCGCCTTCGATGACAGCCCAGTGCCGGCCC
AGAACCGTTCTATCTCTATCCCGGATCAGGACCGCTTCTGGCTGAGCGCAGGTACCAGCTACGCATTCAACAAAGACGCC
TCTGTTGACGTCGGTGTTTCCTACATGCACGGCCAGAAAGTCACCATCAAAGAAGGTCCATACACCTTCGAATCCGTGGG
CAAGGCCTGGCTGTACGGCGCCAACTTCAACTACCGCTTCTAA

Upstream 100 bases:

>100_bases
GGTCTGATTTGTCTGAATGAGATCGGACCCTACAATCGCGCGCTTCCTTGTTACCTTATGTAACATGTTTAAATAATAAA
CACATAATGAGGTTTTGGTC

Downstream 100 bases:

>100_bases
TCCTTTCGACGATGAAGCCAAAGCGCCCTGCGGGGCGCTTTTTTATTGCCTACTATTTGCCGGGCGAAAAAAAACCCGCC
AGTCGACGGGTTGTTTCTGT

Product: long-chain fatty acid outer membrane transporter

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSQKNLFTKSALAAAVAIISSNVSAAGFQLNEFSSAGLGRSYSGEGAMADTAASASRNPALLMMYTRPELSLGAVFIDPD
VDITGKSPSGASLDSKNIAPTAWVPNLHYVQPINDQFAVGGSVTSNYGLATEFNDGYTAGAYGGKTDLTTVNLNLSGAYR
LNQQFSFGLGFDAVYAKAKLERYAGELPKLIAGSGQLPPQLAGPVSQIPADTQISHLKGDKWGFGWNAGILYEVDENNRY
GFTYRSEVKIKFDGDYKSSLPSAYNPLLGALGLPMGTDGTTIPGSLDLNLPEMWEISGYNKVAPQWAIHYSLAYTSWSQF
QELKATGNNGQTLFEKHEGFKDAYRIALGTTYFYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTSYAFNKDA
SVDVGVSYMHGQKVTIKEGPYTFESVGKAWLYGANFNYRF

Sequences:

>Translated_440_residues
MSQKNLFTKSALAAAVAIISSNVSAAGFQLNEFSSAGLGRSYSGEGAMADTAASASRNPALLMMYTRPELSLGAVFIDPD
VDITGKSPSGASLDSKNIAPTAWVPNLHYVQPINDQFAVGGSVTSNYGLATEFNDGYTAGAYGGKTDLTTVNLNLSGAYR
LNQQFSFGLGFDAVYAKAKLERYAGELPKLIAGSGQLPPQLAGPVSQIPADTQISHLKGDKWGFGWNAGILYEVDENNRY
GFTYRSEVKIKFDGDYKSSLPSAYNPLLGALGLPMGTDGTTIPGSLDLNLPEMWEISGYNKVAPQWAIHYSLAYTSWSQF
QELKATGNNGQTLFEKHEGFKDAYRIALGTTYFYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTSYAFNKDA
SVDVGVSYMHGQKVTIKEGPYTFESVGKAWLYGANFNYRF
>Mature_439_residues
SQKNLFTKSALAAAVAIISSNVSAAGFQLNEFSSAGLGRSYSGEGAMADTAASASRNPALLMMYTRPELSLGAVFIDPDV
DITGKSPSGASLDSKNIAPTAWVPNLHYVQPINDQFAVGGSVTSNYGLATEFNDGYTAGAYGGKTDLTTVNLNLSGAYRL
NQQFSFGLGFDAVYAKAKLERYAGELPKLIAGSGQLPPQLAGPVSQIPADTQISHLKGDKWGFGWNAGILYEVDENNRYG
FTYRSEVKIKFDGDYKSSLPSAYNPLLGALGLPMGTDGTTIPGSLDLNLPEMWEISGYNKVAPQWAIHYSLAYTSWSQFQ
ELKATGNNGQTLFEKHEGFKDAYRIALGTTYFYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTSYAFNKDAS
VDVGVSYMHGQKVTIKEGPYTFESVGKAWLYGANFNYRF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=448, Percent_Identity=71.2053571428571, Blast_Score=654, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR001702
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 47707; Mature: 47576

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKNLFTKSALAAAVAIISSNVSAAGFQLNEFSSAGLGRSYSGEGAMADTAASASRNPA
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCE
LLMMYTRPELSLGAVFIDPDVDITGKSPSGASLDSKNIAPTAWVPNLHYVQPINDQFAVG
EEEEEECCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCEEEC
GSVTSNYGLATEFNDGYTAGAYGGKTDLTTVNLNLSGAYRLNQQFSFGLGFDAVYAKAKL
CCCCCCCCEEEECCCCEEECCCCCCCCEEEEEEEECCEEEECCEEECCCCHHHHHHHHHH
ERYAGELPKLIAGSGQLPPQLAGPVSQIPADTQISHLKGDKWGFGWNAGILYEVDENNRY
HHHHHHCCHHHCCCCCCCHHHCCCHHHCCCCCCHHHCCCCCCCCCCCCCEEEEECCCCEE
GFTYRSEVKIKFDGDYKSSLPSAYNPLLGALGLPMGTDGTTIPGSLDLNLPEMWEISGYN
CEEEEEEEEEEECCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEECCCC
KVAPQWAIHYSLAYTSWSQFQELKATGNNGQTLFEKHEGFKDAYRIALGTTYFYDDNWTF
CCCCCEEEEEEEEECCHHHHHHHHHCCCCCCCHHHHHCCHHHHEEEEEEEEEEECCCEEE
RTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTSYAFNKDASVDVGVSYMHGQKVTIKEGP
EECCEECCCCCCCCCCEEECCCCCCEEEECCCCEEECCCCCEEEEEEEECCCEEEEECCC
YTFESVGKAWLYGANFNYRF
CCHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
SQKNLFTKSALAAAVAIISSNVSAAGFQLNEFSSAGLGRSYSGEGAMADTAASASRNPA
CCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCE
LLMMYTRPELSLGAVFIDPDVDITGKSPSGASLDSKNIAPTAWVPNLHYVQPINDQFAVG
EEEEEECCCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCEEEC
GSVTSNYGLATEFNDGYTAGAYGGKTDLTTVNLNLSGAYRLNQQFSFGLGFDAVYAKAKL
CCCCCCCCEEEECCCCEEECCCCCCCCEEEEEEEECCEEEECCEEECCCCHHHHHHHHHH
ERYAGELPKLIAGSGQLPPQLAGPVSQIPADTQISHLKGDKWGFGWNAGILYEVDENNRY
HHHHHHCCHHHCCCCCCCHHHCCCHHHCCCCCCHHHCCCCCCCCCCCCCEEEEECCCCEE
GFTYRSEVKIKFDGDYKSSLPSAYNPLLGALGLPMGTDGTTIPGSLDLNLPEMWEISGYN
CEEEEEEEEEEECCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEECCCC
KVAPQWAIHYSLAYTSWSQFQELKATGNNGQTLFEKHEGFKDAYRIALGTTYFYDDNWTF
CCCCCEEEEEEEEECCHHHHHHHHHCCCCCCCHHHHHCCHHHHEEEEEEEEEEECCCEEE
RTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTSYAFNKDASVDVGVSYMHGQKVTIKEGP
EECCEECCCCCCCCCCEEECCCCCCEEEECCCCEEECCCCCEEEEEEEECCCEEEEECCC
YTFESVGKAWLYGANFNYRF
CCHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]