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The map label for this gene is sbcB [H]

Identifier: 157371451

GI number: 157371451

Start: 3539217

End: 3540644

Strand: Direct

Name: sbcB [H]

Synonym: Spro_3214

Alternate gene names: 157371451

Gene position: 3539217-3540644 (Clockwise)

Preceding gene: 157371450

Following gene: 157371454

Centisome position: 64.95

GC content: 56.93

Gene sequence:

>1428_bases
TTGAGCAGCAAGGCACCGGCCACATTCTACATCCACGACTACGAGACCTTCGGCATAAGCCCATCGATGGACCGCCCGGC
GCAGTTTGCCGGCGTGCGTACCGATATGGATTTCAATATTATCGAAGAGCCGCTGGTCATCTACTGCACCCCGGCCGATG
ATTACCTGCCCGATCCCGAAGCGGTGATGATCACCGGTATTACGCCGCAACTGGCACTGGCCAAGGGCGTTAACGAAGCC
GAGTTTACACGGCAAATTCATCAGGCATTCAGCGTGCCCGGCACCTGTATTCTGGGTTACAACAATATCCGCTTTGATGA
CGAAGTCAGTCGCAATATTTTCTACCGCAACTTCTACGATCCCTATGCTTACAGTTGGCAGAATGGCAACTCACGCTGGG
ATCTGCTCGACGTTATGCGTGCCTGTTATGCACTGCGCCCGGACGGCATCGTCTGGCCGGAGAACGAAGATGGCTTCCCC
AGCTTCCGTCTGGAGCACCTGACCCGCGCCAACGGCGTCGAACATGAACATGCCCATGACGCCATGTCGGACGTTTACGC
CACCATTGCCATGGCCAAACTGGTCAAGCAGGCGCAGCCACGGTTATTTGATTTCCTGTTGCAGCACCGCAACAAACATA
AGCTGAACGCGCTGATCGACATCGCAGAAATGACGCCGTTGGTACACGTTTCCGGCATGTTCGGCGCGGCACGTGGCAAC
ACCAGTTGGGTATCGCCGCTGGCCTGGCACCCGGACAACAAGAACGCGGTGATCATGTGCGATTTGGCCGGTGATATGAC
GCCATTGCTGACGCTGAGCGCCGACGAGCTGCGTGAACGGCTGTATACCCGCCGTGAAGATCTGGCCCCCGGCCAATCGC
CGGTGCCGATCAAACTGGTACATATCAACAAATGTCCGGTGCTGGCACCGGCGAAAACCCTGTTGCCGGAAAATGCCGAG
CGGCTGGGTATCGATCGTCAGGCCTGCCTGCAAAACCTGCAGCTGCTGCGCCAGCATCCGCAAGTGCGCGAAAAAGTGGT
CGCACTGTTCGCCGATGCCGAGCCTTTCAAGGGTTCTGATGATGTCGATGCGCGGCTGTACGACGGTTTCTTCAGCGATG
CCGATAAGGCAACGATGAAAATTATCCAGCAAACCAAGCCGCAGAACCTGCCGGCGCTGGATTTGACCTTCAACGATGGC
CGTCTGAAAGAGCTGCTGTTCCGCTTCCGCGCCCGCAATTACCCCAATACGCTCGATGACACCGAGCAACGCCGCTGGTT
ACAGCATCGTCAGGAAGCCTTAAGCGCCGAGCGGGTGCAGAGCTATGTCCTGCAACTGGAGTCGCTGTATAACCTGCATG
AAGGCGATCAAGAGAAGACCGCGCTGTTGAAAGCGCTGTTTGAATACGGCAAAGAGCTGGTCGGCTGA

Upstream 100 bases:

>100_bases
ATACAGCGCATTTCGGTGATTAACACTAACGACCGCTTGGCATCGTTCATCTCGCCGTTACAATAGGGGCATATTCCCTA
CGCACGCGAGAGATGCGATT

Downstream 100 bases:

>100_bases
CAAAAACAATAAAGGGCGCCCCAAGGCGCCCTTCTTAATACTTACCGAATAAAGCTTAGGCTACGTCTTCGCTAGCCTGT
GGTACCGGCAGGCGGAAGCT

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MSSKAPATFYIHDYETFGISPSMDRPAQFAGVRTDMDFNIIEEPLVIYCTPADDYLPDPEAVMITGITPQLALAKGVNEA
EFTRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQNGNSRWDLLDVMRACYALRPDGIVWPENEDGFP
SFRLEHLTRANGVEHEHAHDAMSDVYATIAMAKLVKQAQPRLFDFLLQHRNKHKLNALIDIAEMTPLVHVSGMFGAARGN
TSWVSPLAWHPDNKNAVIMCDLAGDMTPLLTLSADELRERLYTRREDLAPGQSPVPIKLVHINKCPVLAPAKTLLPENAE
RLGIDRQACLQNLQLLRQHPQVREKVVALFADAEPFKGSDDVDARLYDGFFSDADKATMKIIQQTKPQNLPALDLTFNDG
RLKELLFRFRARNYPNTLDDTEQRRWLQHRQEALSAERVQSYVLQLESLYNLHEGDQEKTALLKALFEYGKELVG

Sequences:

>Translated_475_residues
MSSKAPATFYIHDYETFGISPSMDRPAQFAGVRTDMDFNIIEEPLVIYCTPADDYLPDPEAVMITGITPQLALAKGVNEA
EFTRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQNGNSRWDLLDVMRACYALRPDGIVWPENEDGFP
SFRLEHLTRANGVEHEHAHDAMSDVYATIAMAKLVKQAQPRLFDFLLQHRNKHKLNALIDIAEMTPLVHVSGMFGAARGN
TSWVSPLAWHPDNKNAVIMCDLAGDMTPLLTLSADELRERLYTRREDLAPGQSPVPIKLVHINKCPVLAPAKTLLPENAE
RLGIDRQACLQNLQLLRQHPQVREKVVALFADAEPFKGSDDVDARLYDGFFSDADKATMKIIQQTKPQNLPALDLTFNDG
RLKELLFRFRARNYPNTLDDTEQRRWLQHRQEALSAERVQSYVLQLESLYNLHEGDQEKTALLKALFEYGKELVG
>Mature_474_residues
SSKAPATFYIHDYETFGISPSMDRPAQFAGVRTDMDFNIIEEPLVIYCTPADDYLPDPEAVMITGITPQLALAKGVNEAE
FTRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQNGNSRWDLLDVMRACYALRPDGIVWPENEDGFPS
FRLEHLTRANGVEHEHAHDAMSDVYATIAMAKLVKQAQPRLFDFLLQHRNKHKLNALIDIAEMTPLVHVSGMFGAARGNT
SWVSPLAWHPDNKNAVIMCDLAGDMTPLLTLSADELRERLYTRREDLAPGQSPVPIKLVHINKCPVLAPAKTLLPENAER
LGIDRQACLQNLQLLRQHPQVREKVVALFADAEPFKGSDDVDARLYDGFFSDADKATMKIIQQTKPQNLPALDLTFNDGR
LKELLFRFRARNYPNTLDDTEQRRWLQHRQEALSAERVQSYVLQLESLYNLHEGDQEKTALLKALFEYGKELVG

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=472, Percent_Identity=69.2796610169492, Blast_Score=703, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54085; Mature: 53954

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKAPATFYIHDYETFGISPSMDRPAQFAGVRTDMDFNIIEEPLVIYCTPADDYLPDPE
CCCCCCEEEEEECCEECCCCCCCCCCHHHCCCCCCCCCCEECCCEEEEEECCCCCCCCCC
AVMITGITPQLALAKGVNEAEFTRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYD
EEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCEEEECCCC
PYAYSWQNGNSRWDLLDVMRACYALRPDGIVWPENEDGFPSFRLEHLTRANGVEHEHAHD
CCCEEECCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHCCCCHHHHHH
AMSDVYATIAMAKLVKQAQPRLFDFLLQHRNKHKLNALIDIAEMTPLVHVSGMFGAARGN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCC
TSWVSPLAWHPDNKNAVIMCDLAGDMTPLLTLSADELRERLYTRREDLAPGQSPVPIKLV
CCCCCCEEECCCCCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCEEEE
HINKCPVLAPAKTLLPENAERLGIDRQACLQNLQLLRQHPQVREKVVALFADAEPFKGSD
EECCCCCCCCHHHHCCCCHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCC
DVDARLYDGFFSDADKATMKIIQQTKPQNLPALDLTFNDGRLKELLFRFRARNYPNTLDD
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCH
TEQRRWLQHRQEALSAERVQSYVLQLESLYNLHEGDQEKTALLKALFEYGKELVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSKAPATFYIHDYETFGISPSMDRPAQFAGVRTDMDFNIIEEPLVIYCTPADDYLPDPE
CCCCCEEEEEECCEECCCCCCCCCCHHHCCCCCCCCCCEECCCEEEEEECCCCCCCCCC
AVMITGITPQLALAKGVNEAEFTRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYD
EEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCEEEECCCC
PYAYSWQNGNSRWDLLDVMRACYALRPDGIVWPENEDGFPSFRLEHLTRANGVEHEHAHD
CCCEEECCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHCCCCHHHHHH
AMSDVYATIAMAKLVKQAQPRLFDFLLQHRNKHKLNALIDIAEMTPLVHVSGMFGAARGN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCC
TSWVSPLAWHPDNKNAVIMCDLAGDMTPLLTLSADELRERLYTRREDLAPGQSPVPIKLV
CCCCCCEEECCCCCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCEEEE
HINKCPVLAPAKTLLPENAERLGIDRQACLQNLQLLRQHPQVREKVVALFADAEPFKGSD
EECCCCCCCCHHHHCCCCHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCC
DVDARLYDGFFSDADKATMKIIQQTKPQNLPALDLTFNDGRLKELLFRFRARNYPNTLDD
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCH
TEQRRWLQHRQEALSAERVQSYVLQLESLYNLHEGDQEKTALLKALFEYGKELVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]