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The map label for this gene is dpiA [H]

Identifier: 157371411

GI number: 157371411

Start: 3490437

End: 3491123

Strand: Direct

Name: dpiA [H]

Synonym: Spro_3172

Alternate gene names: 157371411

Gene position: 3490437-3491123 (Clockwise)

Preceding gene: 157371401

Following gene: 157371412

Centisome position: 64.06

GC content: 57.79

Gene sequence:

>687_bases
ATGGAATGGTTGAATATACTGATCGTCGAAGATGAAACGCCGCTGGCGGAGATGCATGCGGAATTTATTCGGCAGAACGG
CGGTTGTCGGCAAATCTGGCTGGCCGGTACCCTGGCGCAAGCCCGTATGATGACTGAGCGCTTCAAACCGGATCTGATCC
TGCTGGATAACTTCCTGCCCGATGGCCAGGGCATTGAGCTGCTGCGTGAGCTGACCCTGAGTGGTTATGCCGGCGGCATC
GTGTTTATCACCGCCGCCAGCGATATGGATACCGTGGCCGAAGCGCTGCGTTACGGGGTGTTCGATTACCTGATCAAACC
CTTGGCTTATGATCGTCTGGCCCACACGCTGCTGCGCTTTAGCCAGCGGCGTCTGGCGCTGAAAGACAAAGCGCGACTTA
GCCAGCACCGCATCGATCAGATGTTCAACACCTACGCACGCGGTGAACAGCAGGCTGCGCTACCAGCGGGCATTGATGAA
CTGACGCTGGTTAAAGTCCGCGCCTTGTTCGAGCACGCTTCCACCAGCCACACCGCTGAAAGCGTTGCGCAAAAGATGGG
GCTAAGCCGGACCACCGCACGCCGCTATCTGGAGTTTTGTACCGCCGCCCAGCAGCTGCGTGCAGAAATCATTTACGGCA
AAGTGGGCCGTCCGCAGCGGATTTATCGCCCCAACCTGCCAGAATAA

Upstream 100 bases:

>100_bases
GTTTATTATTGAGATAATCTTTATTTTACGCGGCAATTAACTTACATTTTATTAGCATGTTGATTGCATATTGAAAGACG
ATGGGGAGACGAGATTCACT

Downstream 100 bases:

>100_bases
GCGGTTATTTGATCGCCCCTGCAAGCTTGAATGTATACCCTATAGCTTTCAAGTCGCAGCTAGGCGCCCAGCTCGCTCAT
CCCCAGGCGCTTACTCGAGT

Product: response regulator receiver/unknown domain-containing protein

Products: NA

Alternate protein names: Destabilizer of plasmid inheritance [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MEWLNILIVEDETPLAEMHAEFIRQNGGCRQIWLAGTLAQARMMTERFKPDLILLDNFLPDGQGIELLRELTLSGYAGGI
VFITAASDMDTVAEALRYGVFDYLIKPLAYDRLAHTLLRFSQRRLALKDKARLSQHRIDQMFNTYARGEQQAALPAGIDE
LTLVKVRALFEHASTSHTAESVAQKMGLSRTTARRYLEFCTAAQQLRAEIIYGKVGRPQRIYRPNLPE

Sequences:

>Translated_228_residues
MEWLNILIVEDETPLAEMHAEFIRQNGGCRQIWLAGTLAQARMMTERFKPDLILLDNFLPDGQGIELLRELTLSGYAGGI
VFITAASDMDTVAEALRYGVFDYLIKPLAYDRLAHTLLRFSQRRLALKDKARLSQHRIDQMFNTYARGEQQAALPAGIDE
LTLVKVRALFEHASTSHTAESVAQKMGLSRTTARRYLEFCTAAQQLRAEIIYGKVGRPQRIYRPNLPE
>Mature_228_residues
MEWLNILIVEDETPLAEMHAEFIRQNGGCRQIWLAGTLAQARMMTERFKPDLILLDNFLPDGQGIELLRELTLSGYAGGI
VFITAASDMDTVAEALRYGVFDYLIKPLAYDRLAHTLLRFSQRRLALKDKARLSQHRIDQMFNTYARGEQQAALPAGIDE
LTLVKVRALFEHASTSHTAESVAQKMGLSRTTARRYLEFCTAAQQLRAEIIYGKVGRPQRIYRPNLPE

Specific function: Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. Could be involved in response to both the presence of citrate and external redox c

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=219, Percent_Identity=64.8401826484018, Blast_Score=288, Evalue=2e-79,
Organism=Escherichia coli, GI1790566, Length=224, Percent_Identity=29.9107142857143, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786911, Length=156, Percent_Identity=33.974358974359, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25884; Mature: 25884

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLNILIVEDETPLAEMHAEFIRQNGGCRQIWLAGTLAQARMMTERFKPDLILLDNFLP
CCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEECCCC
DGQGIELLRELTLSGYAGGIVFITAASDMDTVAEALRYGVFDYLIKPLAYDRLAHTLLRF
CCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQRRLALKDKARLSQHRIDQMFNTYARGEQQAALPAGIDELTLVKVRALFEHASTSHTAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
SVAQKMGLSRTTARRYLEFCTAAQQLRAEIIYGKVGRPQRIYRPNLPE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEWLNILIVEDETPLAEMHAEFIRQNGGCRQIWLAGTLAQARMMTERFKPDLILLDNFLP
CCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEECCCC
DGQGIELLRELTLSGYAGGIVFITAASDMDTVAEALRYGVFDYLIKPLAYDRLAHTLLRF
CCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQRRLALKDKARLSQHRIDQMFNTYARGEQQAALPAGIDELTLVKVRALFEHASTSHTAE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
SVAQKMGLSRTTARRYLEFCTAAQQLRAEIIYGKVGRPQRIYRPNLPE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]