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The map label for this gene is paaE [H]

Identifier: 157371316

GI number: 157371316

Start: 3385556

End: 3386614

Strand: Direct

Name: paaE [H]

Synonym: Spro_3076

Alternate gene names: 157371316

Gene position: 3385556-3386614 (Clockwise)

Preceding gene: 157371315

Following gene: 157371317

Centisome position: 62.13

GC content: 59.11

Gene sequence:

>1059_bases
ATGACGGTCTTCCATCGCCTGAACGTCGCCGCCATCGAGCGCGAAACGCCGGACGCCGTAGCCATCACTCTGCGGGTACC
CGAAGAACTGAAAAGTCACTATTGCTATACGCCCGGCCAGCACCTGACGTTGAAGGCGCTGGTCGACGGCGAAGAGCTGC
GCCGCTGCTACTCCATTTGCAGCTCGCCGCAGGAAGGTTTGCTGCAAATCGGCGTTAAAGCCATTCATCAGGGCCGCTTC
TCTTCGTTCGTTAACCGGCAGCTGTTGGTCGGTGATGCGCTGGAAGTGATGGTGCCGCAAGGGCGATTCGGCTATCAACC
GCAGGCGGAGAACAGCGGTAACTATCTGGCGATTGCGGCCGGTTCCGGCATTACGCCGATGCTGTCGATCATCAAGGCCA
CGTTGCAACTCGAGCCAAACAGCAGCTTCACGCTGATTTACGGCAACCGCAGCAGCCGCTCGGTGATGTTCAAAGAAGCA
CTGTCCGATCTGAAGAACCGCTATCCCCAGCGCTTTCAGCCGCTGTACCTGTTCAGCCAGGAAAATCTTGATAGCCCACT
GCTCAGCGGCCGCATCGACCGTGAGCACCTGCTGGCGATCGGCGATGCATTACTCAATTACCGCGACTATGACCACGCCT
TTATCTGCGGGCCTGAGAGCATGATGGACGACGCCCAGAGCGTACTTGAACAGGCTGGCATGCCCGCCGGGCACATTCAC
AGCGAACGTTTTAACACCAGCGGTATGGTTGCCCGGCCGGTCAATGACGCCAACCGCAACGCCACCCGGGTCGAAATTTT
GCTCGATGGCCGTCGGCTGGATATCGAAGTAGGCGCCCAGGATGACAGCATTCTGGATGCGGCGCTGCGTCAGGGTGCTG
ACCTGCCCTACGCCTGCAAAGGCGGGGTGTGCGCGACCTGCAAGTGCCGGTTAAAGGCCGGTCAGGTGGATATGGCGGTT
AACTACAGCCTGGAGCCGGATCAACTGGCGGCGGGTTACGTATTGAGTTGTCAGTCGTGGCCGCGTGGCGACGGTGTGAT
ATTGGACTTTGACGTATAG

Upstream 100 bases:

>100_bases
AGAAAATCAGCGAATTCGGCTCCACCGCCTGTAAGGCGCTGTACCGCTGTTGCGATTGCCGTGAACCCTTCGACTACTTC
AAATGCATTTAGGAATAACC

Downstream 100 bases:

>100_bases
GAGCCGCCGATGGAAACCCCTTTTGTCCTGCGACAGCAACACCAGCGAGTGGTGACACTGACACTGCATCGCCCAGAGGC
GCGCAACGCCCTGAGCACCC

Product: phenylacetate-CoA oxygenase/reductase subunit PaaK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTVFHRLNVAAIERETPDAVAITLRVPEELKSHYCYTPGQHLTLKALVDGEELRRCYSICSSPQEGLLQIGVKAIHQGRF
SSFVNRQLLVGDALEVMVPQGRFGYQPQAENSGNYLAIAAGSGITPMLSIIKATLQLEPNSSFTLIYGNRSSRSVMFKEA
LSDLKNRYPQRFQPLYLFSQENLDSPLLSGRIDREHLLAIGDALLNYRDYDHAFICGPESMMDDAQSVLEQAGMPAGHIH
SERFNTSGMVARPVNDANRNATRVEILLDGRRLDIEVGAQDDSILDAALRQGADLPYACKGGVCATCKCRLKAGQVDMAV
NYSLEPDQLAAGYVLSCQSWPRGDGVILDFDV

Sequences:

>Translated_352_residues
MTVFHRLNVAAIERETPDAVAITLRVPEELKSHYCYTPGQHLTLKALVDGEELRRCYSICSSPQEGLLQIGVKAIHQGRF
SSFVNRQLLVGDALEVMVPQGRFGYQPQAENSGNYLAIAAGSGITPMLSIIKATLQLEPNSSFTLIYGNRSSRSVMFKEA
LSDLKNRYPQRFQPLYLFSQENLDSPLLSGRIDREHLLAIGDALLNYRDYDHAFICGPESMMDDAQSVLEQAGMPAGHIH
SERFNTSGMVARPVNDANRNATRVEILLDGRRLDIEVGAQDDSILDAALRQGADLPYACKGGVCATCKCRLKAGQVDMAV
NYSLEPDQLAAGYVLSCQSWPRGDGVILDFDV
>Mature_351_residues
TVFHRLNVAAIERETPDAVAITLRVPEELKSHYCYTPGQHLTLKALVDGEELRRCYSICSSPQEGLLQIGVKAIHQGRFS
SFVNRQLLVGDALEVMVPQGRFGYQPQAENSGNYLAIAAGSGITPMLSIIKATLQLEPNSSFTLIYGNRSSRSVMFKEAL
SDLKNRYPQRFQPLYLFSQENLDSPLLSGRIDREHLLAIGDALLNYRDYDHAFICGPESMMDDAQSVLEQAGMPAGHIHS
ERFNTSGMVARPVNDANRNATRVEILLDGRRLDIEVGAQDDSILDAALRQGADLPYACKGGVCATCKCRLKAGQVDMAVN
YSLEPDQLAAGYVLSCQSWPRGDGVILDFDV

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI49574502, Length=217, Percent_Identity=28.110599078341, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI134133308, Length=239, Percent_Identity=27.1966527196653, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787658, Length=352, Percent_Identity=62.5, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1787098, Length=343, Percent_Identity=27.6967930029155, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788104, Length=319, Percent_Identity=26.0188087774295, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790359, Length=209, Percent_Identity=23.9234449760766, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17563928, Length=224, Percent_Identity=26.3392857142857, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323510, Length=206, Percent_Identity=28.1553398058252, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322146, Length=199, Percent_Identity=28.1407035175879, Blast_Score=76, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281366101, Length=221, Percent_Identity=26.2443438914027, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24662934, Length=221, Percent_Identity=26.2443438914027, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24662938, Length=221, Percent_Identity=26.2443438914027, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38772; Mature: 38640

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFHRLNVAAIERETPDAVAITLRVPEELKSHYCYTPGQHLTLKALVDGEELRRCYSIC
CCEEEECCEEEEECCCCCEEEEEEECCHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHHH
SSPQEGLLQIGVKAIHQGRFSSFVNRQLLVGDALEVMVPQGRFGYQPQAENSGNYLAIAA
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEE
GSGITPMLSIIKATLQLEPNSSFTLIYGNRSSRSVMFKEALSDLKNRYPQRFQPLYLFSQ
CCCCHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEC
ENLDSPLLSGRIDREHLLAIGDALLNYRDYDHAFICGPESMMDDAQSVLEQAGMPAGHIH
CCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCC
SERFNTSGMVARPVNDANRNATRVEILLDGRRLDIEVGAQDDSILDAALRQGADLPYACK
CCCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCEECC
GGVCATCKCRLKAGQVDMAVNYSLEPDQLAAGYVLSCQSWPRGDGVILDFDV
CCEEEEEEEEEECCCEEEEEECCCCHHHHCCCEEEEECCCCCCCCEEEEECC
>Mature Secondary Structure 
TVFHRLNVAAIERETPDAVAITLRVPEELKSHYCYTPGQHLTLKALVDGEELRRCYSIC
CEEEECCEEEEECCCCCEEEEEEECCHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHHH
SSPQEGLLQIGVKAIHQGRFSSFVNRQLLVGDALEVMVPQGRFGYQPQAENSGNYLAIAA
CCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEE
GSGITPMLSIIKATLQLEPNSSFTLIYGNRSSRSVMFKEALSDLKNRYPQRFQPLYLFSQ
CCCCHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEC
ENLDSPLLSGRIDREHLLAIGDALLNYRDYDHAFICGPESMMDDAQSVLEQAGMPAGHIH
CCCCCCHHCCCCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCC
SERFNTSGMVARPVNDANRNATRVEILLDGRRLDIEVGAQDDSILDAALRQGADLPYACK
CCCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCEECC
GGVCATCKCRLKAGQVDMAVNYSLEPDQLAAGYVLSCQSWPRGDGVILDFDV
CCEEEEEEEEEECCCEEEEEECCCCHHHHCCCEEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]