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The map label for this gene is spk1 [H]

Identifier: 157371254

GI number: 157371254

Start: 3316896

End: 3318338

Strand: Direct

Name: spk1 [H]

Synonym: Spro_3014

Alternate gene names: 157371254

Gene position: 3316896-3318338 (Clockwise)

Preceding gene: 157371253

Following gene: 157371255

Centisome position: 60.87

GC content: 60.5

Gene sequence:

>1443_bases
ATGTCGGGAACCGGGGTAAGCAAACCGAATTCAAACAGCCTGCCGATCGGCTATAGGTTCAATGAATTCGAGATCAAGGA
AGCTATCGGCGAAGGCGGTTTCGGCATCGTCTACCGCGCCTACGATCATCAGCTGGAACGCACCATCGCCATCAAAGAGT
ACATGCCGACCTCGCTGGCGATGCGCAATGACGATCTGAGCATCGGGCTACGCGGTGAGCGTTTCAGCAAAACCTTCCAG
GCCGGGTTAAACAGCTTTATTCAGGAAGCCCGCCTGCTGGCGCGTTTCTCACACCCAGGGCTTCTGCACGTACTGCGCTT
TTGGGAAGAGAACGGTACCGCCTACATGGGCACCCAGTTTTACAGCGGCACTACCCTGAAGAACCTGCAGGCGCAGCAGC
CGGAGAAAATCGACGAGGCCTGGATCCGCAGACTGTTGCCACCGCTGTTCAGCGCCATCAACACCATCCATCAGGAAGGT
TATCTGCACCGCGACATTTCACTGGATAACATTCAGATCCAGGAAAACCAGTTGCCGGTGCTGCTGGACTTCGGCTCAGC
GCGCAAAGAGATCGGCAACCTGTCCGACGAAACGGAAATCATGCTCAAACCGGGCTTTGCGCCGATTGAGCAATACACCG
AGAACAGCGACGGTGAGCAAGGCCCCTGGACCGACATTTACGCTCTGGGCGCCGTGCTGCATACGCTGATCGTCGGTTCA
CCGCCGCCGGTCAGCGTGGTGCGCAGCATCGAGGACAGCTACCAACCGCTGACCGAACGGCGCCCGGCGGGGTATTCACT
GGAACTGCTGCGCACTATCGACCATGCGCTGGCGTTGAAACCGGAAGACCGGCCACAAACCATCGACGAAATGGCCGAAC
TGCTGCATCTGCCGATTGCCGATGAAAACGAAATCATCAGCACCCCGGCCGCCGCACCGGAAAACCTGCTGGTGGCCACC
AATCCGGCCGCCGGTGCCGCAGCGGCAGGCGCCGTTACCGCGCACGGCATGAAGCTCACACGCCCGATGATGGCAGGTGC
AGGCGTGGCCGCTTTGCTGGTGATCGGCGTCATCGCCTGGCTAAGCGGCGGCGACAGTACCCCTGCCCCGATAGCGGCCA
ATACGCCAGACAGTGCAGCGGTGGATAAACCCATAACGCCGCCACAAAGCGCACCGCAGACGGCCGAACAGCCACCTGCA
GCCCAGACCCCTCCGGCACCACCGCCGGTGGCACTGGTGTATTTCAAACTGCAACCCGGTGAGCAGGTCAGCCTGGACGG
CAAGCCCCAGCAGGTGACCCCAGGTGACAACGGTTTTGCCCGCCTGAATTTGGCACCGGGCAGCTATCAGCTGGAAATCC
GCCATAACGACCAGTTACGCCGCCAACAGCTCAGCATCGAGAACGCCGGCACCTGGCTGGTCAACCCGGTCGTCGCAGGC
TAA

Upstream 100 bases:

>100_bases
ACTGCATATCGCGCTGCAGCAAAACGAGTTTATTTGTCAATTTCAGGCATAACGCCGCGGCCGCCGGTATGGCGGCCATC
GTTCACAGAGAGTCATCATT

Downstream 100 bases:

>100_bases
CCCTCCGCTTTTCCGGCCCGACACCGCGGGCCTTCACCGTATTTTCATGAGATTGACGCATGCGTCATTCACAGAGGACG
TTCTCATGTTGGATCGTATT

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: stoPK-1 [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MSGTGVSKPNSNSLPIGYRFNEFEIKEAIGEGGFGIVYRAYDHQLERTIAIKEYMPTSLAMRNDDLSIGLRGERFSKTFQ
AGLNSFIQEARLLARFSHPGLLHVLRFWEENGTAYMGTQFYSGTTLKNLQAQQPEKIDEAWIRRLLPPLFSAINTIHQEG
YLHRDISLDNIQIQENQLPVLLDFGSARKEIGNLSDETEIMLKPGFAPIEQYTENSDGEQGPWTDIYALGAVLHTLIVGS
PPPVSVVRSIEDSYQPLTERRPAGYSLELLRTIDHALALKPEDRPQTIDEMAELLHLPIADENEIISTPAAAPENLLVAT
NPAAGAAAAGAVTAHGMKLTRPMMAGAGVAALLVIGVIAWLSGGDSTPAPIAANTPDSAAVDKPITPPQSAPQTAEQPPA
AQTPPAPPPVALVYFKLQPGEQVSLDGKPQQVTPGDNGFARLNLAPGSYQLEIRHNDQLRRQQLSIENAGTWLVNPVVAG

Sequences:

>Translated_480_residues
MSGTGVSKPNSNSLPIGYRFNEFEIKEAIGEGGFGIVYRAYDHQLERTIAIKEYMPTSLAMRNDDLSIGLRGERFSKTFQ
AGLNSFIQEARLLARFSHPGLLHVLRFWEENGTAYMGTQFYSGTTLKNLQAQQPEKIDEAWIRRLLPPLFSAINTIHQEG
YLHRDISLDNIQIQENQLPVLLDFGSARKEIGNLSDETEIMLKPGFAPIEQYTENSDGEQGPWTDIYALGAVLHTLIVGS
PPPVSVVRSIEDSYQPLTERRPAGYSLELLRTIDHALALKPEDRPQTIDEMAELLHLPIADENEIISTPAAAPENLLVAT
NPAAGAAAAGAVTAHGMKLTRPMMAGAGVAALLVIGVIAWLSGGDSTPAPIAANTPDSAAVDKPITPPQSAPQTAEQPPA
AQTPPAPPPVALVYFKLQPGEQVSLDGKPQQVTPGDNGFARLNLAPGSYQLEIRHNDQLRRQQLSIENAGTWLVNPVVAG
>Mature_479_residues
SGTGVSKPNSNSLPIGYRFNEFEIKEAIGEGGFGIVYRAYDHQLERTIAIKEYMPTSLAMRNDDLSIGLRGERFSKTFQA
GLNSFIQEARLLARFSHPGLLHVLRFWEENGTAYMGTQFYSGTTLKNLQAQQPEKIDEAWIRRLLPPLFSAINTIHQEGY
LHRDISLDNIQIQENQLPVLLDFGSARKEIGNLSDETEIMLKPGFAPIEQYTENSDGEQGPWTDIYALGAVLHTLIVGSP
PPVSVVRSIEDSYQPLTERRPAGYSLELLRTIDHALALKPEDRPQTIDEMAELLHLPIADENEIISTPAAAPENLLVATN
PAAGAAAAGAVTAHGMKLTRPMMAGAGVAALLVIGVIAWLSGGDSTPAPIAANTPDSAAVDKPITPPQSAPQTAEQPPAA
QTPPAPPPVALVYFKLQPGEQVSLDGKPQQVTPGDNGFARLNLAPGSYQLEIRHNDQLRRQQLSIENAGTWLVNPVVAG

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI121114283, Length=271, Percent_Identity=22.5092250922509, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI7662170, Length=224, Percent_Identity=23.2142857142857, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI41872374, Length=267, Percent_Identity=26.9662921348315, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI38569491, Length=270, Percent_Identity=24.8148148148148, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI37596297, Length=220, Percent_Identity=24.0909090909091, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI225735561, Length=276, Percent_Identity=25.7246376811594, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4885563, Length=223, Percent_Identity=26.0089686098655, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI217330634, Length=226, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI83627721, Length=279, Percent_Identity=24.0143369175627, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI30089962, Length=224, Percent_Identity=27.2321428571429, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI30089960, Length=224, Percent_Identity=27.2321428571429, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI299829215, Length=208, Percent_Identity=21.6346153846154, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI57222269, Length=232, Percent_Identity=22.8448275862069, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI41872673, Length=272, Percent_Identity=25.7352941176471, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71985222, Length=269, Percent_Identity=27.5092936802974, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71985227, Length=269, Percent_Identity=27.5092936802974, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565634, Length=219, Percent_Identity=23.7442922374429, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI86562808, Length=287, Percent_Identity=24.7386759581882, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193208263, Length=246, Percent_Identity=22.7642276422764, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533246, Length=246, Percent_Identity=22.7642276422764, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71997537, Length=246, Percent_Identity=22.7642276422764, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324557, Length=274, Percent_Identity=25.1824817518248, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321126, Length=286, Percent_Identity=25.5244755244755, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321780, Length=273, Percent_Identity=24.9084249084249, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325104, Length=238, Percent_Identity=23.9495798319328, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319328, Length=280, Percent_Identity=23.2142857142857, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45553327, Length=247, Percent_Identity=23.8866396761134, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45551867, Length=247, Percent_Identity=23.8866396761134, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45553329, Length=247, Percent_Identity=23.8866396761134, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550727, Length=247, Percent_Identity=23.8866396761134, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20128911, Length=296, Percent_Identity=25.3378378378378, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281361563, Length=295, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356423, Length=295, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21358073, Length=273, Percent_Identity=24.1758241758242, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161077232, Length=281, Percent_Identity=26.3345195729537, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161077230, Length=281, Percent_Identity=26.3345195729537, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24655167, Length=281, Percent_Identity=26.3345195729537, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076714, Length=253, Percent_Identity=24.5059288537549, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550904, Length=282, Percent_Identity=26.9503546099291, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550091, Length=282, Percent_Identity=26.9503546099291, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17136516, Length=274, Percent_Identity=21.8978102189781, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 52047; Mature: 51915

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTGVSKPNSNSLPIGYRFNEFEIKEAIGEGGFGIVYRAYDHQLERTIAIKEYMPTSLA
CCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHE
MRNDDLSIGLRGERFSKTFQAGLNSFIQEARLLARFSHPGLLHVLRFWEENGTAYMGTQF
ECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEE
YSGTTLKNLQAQQPEKIDEAWIRRLLPPLFSAINTIHQEGYLHRDISLDNIQIQENQLPV
ECCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCE
LLDFGSARKEIGNLSDETEIMLKPGFAPIEQYTENSDGEQGPWTDIYALGAVLHTLIVGS
EEECCHHHHHHCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
PPPVSVVRSIEDSYQPLTERRPAGYSLELLRTIDHALALKPEDRPQTIDEMAELLHLPIA
CCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
DENEIISTPAAAPENLLVATNPAAGAAAAGAVTAHGMKLTRPMMAGAGVAALLVIGVIAW
CCCCEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHH
LSGGDSTPAPIAANTPDSAAVDKPITPPQSAPQTAEQPPAAQTPPAPPPVALVYFKLQPG
HCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
EQVSLDGKPQQVTPGDNGFARLNLAPGSYQLEIRHNDQLRRQQLSIENAGTWLVNPVVAG
CEECCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure 
SGTGVSKPNSNSLPIGYRFNEFEIKEAIGEGGFGIVYRAYDHQLERTIAIKEYMPTSLA
CCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHE
MRNDDLSIGLRGERFSKTFQAGLNSFIQEARLLARFSHPGLLHVLRFWEENGTAYMGTQF
ECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEE
YSGTTLKNLQAQQPEKIDEAWIRRLLPPLFSAINTIHQEGYLHRDISLDNIQIQENQLPV
ECCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCCCE
LLDFGSARKEIGNLSDETEIMLKPGFAPIEQYTENSDGEQGPWTDIYALGAVLHTLIVGS
EEECCHHHHHHCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
PPPVSVVRSIEDSYQPLTERRPAGYSLELLRTIDHALALKPEDRPQTIDEMAELLHLPIA
CCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
DENEIISTPAAAPENLLVATNPAAGAAAAGAVTAHGMKLTRPMMAGAGVAALLVIGVIAW
CCCCEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHH
LSGGDSTPAPIAANTPDSAAVDKPITPPQSAPQTAEQPPAAQTPPAPPPVALVYFKLQPG
HCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCC
EQVSLDGKPQQVTPGDNGFARLNLAPGSYQLEIRHNDQLRRQQLSIENAGTWLVNPVVAG
CEECCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA