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The map label for this gene is pcpR [H]

Identifier: 157371234

GI number: 157371234

Start: 3291978

End: 3292910

Strand: Direct

Name: pcpR [H]

Synonym: Spro_2994

Alternate gene names: 157371234

Gene position: 3291978-3292910 (Clockwise)

Preceding gene: 157371232

Following gene: 157371235

Centisome position: 60.42

GC content: 57.77

Gene sequence:

>933_bases
ATGAATTTATCCAACGTCGATCTTAATCTTCTGGTGGTGTTTGAGGCGTTGTACCAAACGCGTAATGTCACCGTCGCCGG
CCAACGCCTGAACCGCGCTCAACCCTCGGTAAGTAATGCGCTGGCCCGGCTGCGTACCCTGTTTGACGATCCATTGTTCG
TCCGCAGCGGCGGCGGCATGCTGCCCACCGCCCGTGCTCACCAACTGATGCTGCAGATACAACCGGTGTTGGAACAGATC
CATCAGGCATTAACGCCGCCGACCCGTTTCGATCCGGCAACGGCCAGCCAACGCCGTTTTAGGCTGGCAGCCGGTGATTA
TGCGGATATCACACTGTTACCCACCATCATCAGTCGGCTGCGTCAGGCTGCGCCCGGTATTGATATCCGCGTATCACGGC
TGGATCGGCGCACGGTGGTGCAACAGCTTGAACGTGGAGAGATAGATGTCGCCCTGGGCGGGCATCTTGAAGTGCCGGAA
GGCATGCTGGTGCAGCCGTTATTTAACGAGAGTTTCACCTGTATCGCCAGCCGACATCACCCGCAGATAGCGGCCGAAAG
CTGGAATTTGCAGCAATACATTGGCCTGCCCCATGCGCTTTATGCGCCGTCGGACGACGGTTCGGCACGCGGGATCATCG
ATCAGAGGTTGACTGAAATGGGGCTGGAGCGGCGGGTCGCCGCGACGTTTTCACATATTATCGCGCTACCTGCCGTGGTC
GCGGGTAGCGATCTGATAGCCACCCTTGCCACCAGCGTTGCCCGGCAATTTGCCGATCCTTCACGAATTCAGTTCCTGCC
GCTCCCCAGTGAATTGGCTATGCCTGCCTTCCCTATCGAATGTGTCGCCGGCCGGCAGGTTAAACGCGATCCTGCGCTGG
CATGGTTATGCGACACTCTCAGCCAGCTAAATCTTCCTTCTTTTCACCGTTAA

Upstream 100 bases:

>100_bases
CATCGCCACACCTATGTTGTTATTGAATCAGCGTGCTCTCAGCCTAAACAACGCGGTATGATTCTGGAAATGGATTATCT
GTATATAGAGTATTCATAAT

Downstream 100 bases:

>100_bases
TCATCCACTCTGCTGTTTTAACAACCAAGCCAGGCGCCCCAGCGCGAGTGGCTTCGCGTCCAGACAAATAGGAATCCTCC
TAAATTACATTCCGCTTATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNLSNVDLNLLVVFEALYQTRNVTVAGQRLNRAQPSVSNALARLRTLFDDPLFVRSGGGMLPTARAHQLMLQIQPVLEQI
HQALTPPTRFDPATASQRRFRLAAGDYADITLLPTIISRLRQAAPGIDIRVSRLDRRTVVQQLERGEIDVALGGHLEVPE
GMLVQPLFNESFTCIASRHHPQIAAESWNLQQYIGLPHALYAPSDDGSARGIIDQRLTEMGLERRVAATFSHIIALPAVV
AGSDLIATLATSVARQFADPSRIQFLPLPSELAMPAFPIECVAGRQVKRDPALAWLCDTLSQLNLPSFHR

Sequences:

>Translated_310_residues
MNLSNVDLNLLVVFEALYQTRNVTVAGQRLNRAQPSVSNALARLRTLFDDPLFVRSGGGMLPTARAHQLMLQIQPVLEQI
HQALTPPTRFDPATASQRRFRLAAGDYADITLLPTIISRLRQAAPGIDIRVSRLDRRTVVQQLERGEIDVALGGHLEVPE
GMLVQPLFNESFTCIASRHHPQIAAESWNLQQYIGLPHALYAPSDDGSARGIIDQRLTEMGLERRVAATFSHIIALPAVV
AGSDLIATLATSVARQFADPSRIQFLPLPSELAMPAFPIECVAGRQVKRDPALAWLCDTLSQLNLPSFHR
>Mature_310_residues
MNLSNVDLNLLVVFEALYQTRNVTVAGQRLNRAQPSVSNALARLRTLFDDPLFVRSGGGMLPTARAHQLMLQIQPVLEQI
HQALTPPTRFDPATASQRRFRLAAGDYADITLLPTIISRLRQAAPGIDIRVSRLDRRTVVQQLERGEIDVALGGHLEVPE
GMLVQPLFNESFTCIASRHHPQIAAESWNLQQYIGLPHALYAPSDDGSARGIIDQRLTEMGLERRVAATFSHIIALPAVV
AGSDLIATLATSVARQFADPSRIQFLPLPSELAMPAFPIECVAGRQVKRDPALAWLCDTLSQLNLPSFHR

Specific function: Transcriptional activator for the pcpA, pcpB and pcpE genes for pentachlorophenol (PCP) degradation. Essential for PCP degradation [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=273, Percent_Identity=32.2344322344322, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87081766, Length=298, Percent_Identity=26.8456375838926, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790147, Length=307, Percent_Identity=25.7328990228013, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786820, Length=277, Percent_Identity=24.187725631769, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34153; Mature: 34153

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSNVDLNLLVVFEALYQTRNVTVAGQRLNRAQPSVSNALARLRTLFDDPLFVRSGGGM
CCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCC
LPTARAHQLMLQIQPVLEQIHQALTPPTRFDPATASQRRFRLAAGDYADITLLPTIISRL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHHH
RQAAPGIDIRVSRLDRRTVVQQLERGEIDVALGGHLEVPEGMLVQPLFNESFTCIASRHH
HHHCCCCEEEHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCEECHHHCCCEEEEECCCC
PQIAAESWNLQQYIGLPHALYAPSDDGSARGIIDQRLTEMGLERRVAATFSHIIALPAVV
CCCHHCCCCHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSDLIATLATSVARQFADPSRIQFLPLPSELAMPAFPIECVAGRQVKRDPALAWLCDTL
CCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHH
SQLNLPSFHR
HHCCCCCCCC
>Mature Secondary Structure
MNLSNVDLNLLVVFEALYQTRNVTVAGQRLNRAQPSVSNALARLRTLFDDPLFVRSGGGM
CCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCC
LPTARAHQLMLQIQPVLEQIHQALTPPTRFDPATASQRRFRLAAGDYADITLLPTIISRL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEECCCCCHHHHHHHHHHHH
RQAAPGIDIRVSRLDRRTVVQQLERGEIDVALGGHLEVPEGMLVQPLFNESFTCIASRHH
HHHCCCCEEEHHHHHHHHHHHHHHCCCEEEEECCCEECCCCCEECHHHCCCEEEEECCCC
PQIAAESWNLQQYIGLPHALYAPSDDGSARGIIDQRLTEMGLERRVAATFSHIIALPAVV
CCCHHCCCCHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSDLIATLATSVARQFADPSRIQFLPLPSELAMPAFPIECVAGRQVKRDPALAWLCDTL
CCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHH
SQLNLPSFHR
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12169590 [H]